iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

mRNA Expression
GEO	FFGED
Protein-protein Interaction
IID	iRefIndex	HINT	Mentha
Post-translational Modifications (PTMs)
CPLM	dbPAF	BioGRID
Protein Expression/Proteomics
GPMDB

Status

Reviewed

Details

Family	Domain	References (PMIDs)
UBD/ZnF/UBZ	UBZ	17550899; 21911365

Classification

Family	E-value	Score	Start	End
UBD/ZnF/UBZ	5.70e-07	28.2	12	33

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/ZnF/UBZ

   S: 2    lvCPvCqkmvdqtdfeeHlDeC 23
            +CP+C+  v  +++++HlD C
   Q: 12   ISCPICSRKVFFSLINSHLDIC 33
           69******************** PP

Organism

Saccharomyces cerevisiae

Functional Description
(View)

Involved in the maintenance of proper DNA topology and chromosome integrity via annealing of single-stranded DNA breaks. Modulates DNA polymerase delta during replication or replication-associated repair. May function as a modulator for SGS1 when DNA is damaged.

Protein Sequence
(Fasta)

MSNKRTSVEQ LISCPICSRK VFFSLINSHL DICGKEKSKP SSRPQTVSSL LAGPKKRKQA 60
NSEKFIDLEN KDHEIKPGLK SESDDIEIVE NESKRFKAAP STDFAKSIVE PASSRDQLHN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGTAACA AGAGGACATC TGTAGAACAG CTCATATCAT GCCCAATTTG CTCTAGAAAA 60
GTCTTTTTTT CCTTAATCAA CTCTCATCTT GACATATGTG GCAAGGAAAA GTCAAAGCCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0460--Magnesium
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR003593--AAA+_ATPase
IPR032423--AAA_assoc_2
IPR003959--ATPase_AAA_core
IPR008921--DNA_pol3_clamp-load_cplx_C
IPR021886--MgsA_C
IPR027417--P-loop_NTPase
IPR006642--Znf_Rad18_put

Pfam

PF00004--AAA
PF16193--AAA_assoc_2
PF12002--MgsA_C

SMART

SM00382--AAA
SM00734--ZnF_Rad18

Gene Ontology

GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0003677--F:DNA binding
GO:0008047--F:enzyme activator activity
GO:0046872--F:metal ion binding
GO:0043142--F:single-stranded DNA-dependent ATPase activity
GO:0006281--P:DNA repair
GO:0033567--P:DNA replication, Okazaki fragment processing
GO:0000733--P:DNA strand renaturation
GO:0006282--P:regulation of DNA repair

KEGG

sce:YNL218W

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002134	Ailuropoda melanoleuca	46.02	8.00e-103	365.00
IUUC-Atr-002635	Amborella trichopoda	34.47	3.00e-72	263.00
IUUC-Apl-003962	Anas platyrhynchos	45.43	1.00e-106	377.00
IUUC-Aca-005219	Anolis carolinensis	48.70	4.00e-87	312.00
IUUC-Aly-005664	Arabidopsis lyrata	43.33	4.00e-99	353.00
IUUC-Ath-007605	Arabidopsis thaliana	41.70	8.00e-97	345.00
IUUC-Ago-007747	Ashbya gossypii	59.16	0.00e+00	687.00
IUUC-Acl-008260	Aspergillus clavatus	44.40	8.00e-105	372.00
IUUC-Afl-008493	Aspergillus flavus	39.07	9.00e-107	378.00
IUUC-Afu-008892	Aspergillus fumigatus	40.24	2.00e-111	394.00
IUUC-Ani-009289	Aspergillus nidulans	40.59	1.00e-108	384.00
IUUC-Ang-009599	Aspergillus niger	40.31	5.00e-108	382.00
IUUC-Aor-009987	Aspergillus oryzae	39.07	8.00e-107	378.00
IUUC-Ate-010577	Aspergillus terreus	38.90	1.00e-105	374.00
IUUC-Ame-010756	Astyanax mexicanus	34.61	2.00e-55	207.00
IUUC-Bgr-012158	Blumeria graminis	40.14	2.00e-107	380.00
IUUC-Bta-013537	Bos taurus	44.07	1.00e-99	355.00
IUUC-Bci-013965	Botrytis cinerea	38.37	6.00e-107	379.00
IUUC-Bol-015473	Brassica oleracea	43.18	3.00e-94	337.00
IUUC-Bra-017208	Brassica rapa	41.82	7.00e-89	318.00
IUUC-Cja-019193	Callithrix jacchus	45.64	6.00e-104	369.00
IUUC-Cfa-020149	Canis familiaris	46.58	2.00e-103	367.00
IUUC-Cpo-021486	Cavia porcellus	45.80	7.00e-103	365.00
IUUC-Csa-024006	Chlorocebus sabaeus	45.86	2.00e-103	367.00
IUUC-Cho-024632	Choloepus hoffmanni	41.90	3.00e-69	253.00
IUUC-Cne-026982	Cryptococcus neoformans	41.64	1.00e-71	261.00
IUUC-Dre-027822	Danio rerio	40.04	8.00e-106	375.00
IUUC-Dno-029727	Dasypus novemcinctus	46.50	3.00e-103	367.00
IUUC-Dor-030227	Dipodomys ordii	45.24	3.00e-81	294.00
IUUC-Dse-031247	Dothistroma septosporum	38.22	2.00e-101	360.00
IUUC-Ete-033089	Echinops telfairi	45.41	2.00e-99	354.00
IUUC-Eca-033998	Equus caballus	46.79	1.00e-87	314.00
IUUC-Eeu-035147	Erinaceus europaeus	46.53	4.00e-103	366.00
IUUC-Fca-036247	Felis catus	46.12	7.00e-88	316.00
IUUC-Fal-037605	Ficedula albicollis	45.92	8.00e-87	311.00
IUUC-Fox-038016	Fusarium oxysporum	37.63	1.00e-94	338.00
IUUC-Fso-038200	Fusarium solani	37.73	2.00e-95	341.00
IUUC-Gmo-039155	Gadus morhua	36.41	1.00e-89	322.00
IUUC-Ggr-040037	Gaeumannomyces graminis	37.36	1.00e-100	358.00
IUUC-Gga-041277	Gallus gallus	39.90	2.00e-108	384.00
IUUC-Gac-042576	Gasterosteus aculeatus	38.33	3.00e-110	390.00
IUUC-Gma-043574	Glycine max	39.29	3.00e-88	317.00
IUUC-Ggo-045359	Gorilla gorilla	45.64	1.00e-103	368.00
IUUC-Hsa-045689	Homo sapiens	45.64	4.00e-104	370.00
IUUC-Itr-048239	Ictidomys tridecemlineatus	46.02	3.00e-103	367.00
IUUC-Kpa-049277	Komagataella pastoris	44.70	9.00e-127	444.00
IUUC-Lch-049430	Latimeria chalumnae	37.19	2.00e-50	190.00
IUUC-Loc-052461	Lepisosteus oculatus	46.00	8.00e-106	375.00
IUUC-Lma-053060	Leptosphaeria maculans	37.13	4.00e-98	349.00
IUUC-Laf-053418	Loxodonta africana	46.31	3.00e-104	370.00
IUUC-Mcc-055094	Macaca mulatta	45.86	7.00e-104	369.00
IUUC-Meu-056838	Macropus eugenii	40.31	5.00e-58	216.00
IUUC-Mor-057036	Magnaporthe oryzae	37.69	2.00e-100	357.00
IUUC-Mtr-057969	Medicago truncatula	40.22	8.00e-92	328.00
IUUC-Mla-059065	Melampsora laricipopulina	37.67	4.00e-76	276.00
IUUC-Mga-059360	Meleagris gallopavo	46.81	9.00e-98	348.00
IUUC-Mmr-060962	Microcebus murinus	45.76	6.00e-105	372.00
IUUC-Mdo-062007	Monodelphis domestica	45.51	1.00e-102	365.00
IUUC-Mmu-063806	Mus musculus	46.24	1.00e-104	371.00
IUUC-Mac-064594	Musa acuminata	35.27	3.00e-31	127.00
IUUC-Mpu-066476	Mustela putorius furo	46.02	1.00e-103	368.00
IUUC-Mlu-067439	Myotis lucifugus	45.07	5.00e-93	333.00
IUUC-Nfi-068391	Neosartorya fischeri	41.48	4.00e-112	396.00
IUUC-Ncr-068746	Neurospora crassa	44.02	3.00e-91	327.00
IUUC-Nle-069387	Nomascus leucogenys	45.86	5.00e-104	369.00
IUUC-Opr-070903	Ochotona princeps	50.00	3.00e-31	127.00
IUUC-Ont-071546	Oreochromis niloticus	39.38	2.00e-107	380.00
IUUC-Oan-073696	Ornithorhynchus anatinus	47.84	1.00e-84	304.00
IUUC-Ocu-074768	Oryctolagus cuniculus	46.09	2.00e-102	364.00
IUUC-Oin-079459	Oryza indica	40.51	8.00e-70	256.00
IUUC-Ola-087403	Oryzias latipes	39.11	2.00e-109	387.00
IUUC-Oga-088904	Otolemur garnettii	46.36	2.00e-104	370.00
IUUC-Oar-089703	Ovis aries	44.22	7.00e-39	151.00
IUUC-Ptr-090666	Pan troglodytes	45.64	5.00e-104	369.00
IUUC-Pan-092020	Papio anubis	46.88	3.00e-89	319.00
IUUC-Psi-092949	Pelodiscus sinensis	46.22	8.00e-110	388.00
IUUC-Pma-094432	Petromyzon marinus	34.95	2.00e-51	194.00
IUUC-Pno-095095	Phaeosphaeria nodorum	38.05	5.00e-104	369.00
IUUC-Ppa-095376	Physcomitrella patens	36.76	2.00e-40	159.00
IUUC-Pfo-096882	Poecilia formosa	39.13	4.00e-110	389.00
IUUC-Pab-098159	Pongo abelii	45.86	8.00e-104	369.00
IUUC-Pop-098867	Populus trichocarpa	41.31	1.00e-92	331.00
IUUC-Pca-100549	Procavia capensis	45.80	3.00e-103	367.00
IUUC-Pva-102427	Pteropus vampyrus	45.80	2.00e-101	361.00
IUUC-Pgr-103584	Puccinia graminis	38.99	3.00e-82	297.00
IUUC-Ptt-103965	Puccinia triticina	40.55	6.00e-46	176.00
IUUC-Pte-104110	Pyrenophora teres	44.24	1.00e-99	354.00
IUUC-Pyt-104578	Pyrenophora triticirepentis	37.33	1.00e-99	354.00
IUUC-Rno-106096	Rattus norvegicus	46.24	8.00e-105	372.00
IUUC-Sha-106678	Sarcophilus harrisii	44.54	7.00e-104	369.00
IUUC-Sja-107709	Schizosaccharomyces japonicus	43.22	3.00e-112	396.00
IUUC-Spo-108286	Schizosaccharomyces pombe	42.75	1.00e-115	407.00
IUUC-Smo-109453	Selaginella moellendorffii	41.59	9.00e-88	315.00
IUUC-Sly-111329	Solanum lycopersicum	41.18	7.00e-94	335.00
IUUC-Stu-112498	Solanum tuberosum	40.52	8.00e-94	335.00
IUUC-Sre-115000	Sporisorium reilianum	39.97	1.00e-100	358.00
IUUC-Ssc-115336	Sus scrofa	43.58	7.00e-100	355.00
IUUC-Tgu-116596	Taeniopygia guttata	39.51	7.00e-109	385.00
IUUC-Tru-117850	Takifugu rubripes	40.71	6.00e-113	399.00
IUUC-Tsy-118903	Tarsius syrichta	45.99	4.00e-72	263.00
IUUC-Tni-120817	Tetraodon nigroviridis	39.76	5.00e-108	382.00
IUUC-Tca-121843	Theobroma cacao	38.63	4.00e-87	313.00
IUUC-Tre-121913	Trichoderma reesei	45.06	2.00e-97	347.00
IUUC-Tvi-122613	Trichoderma virens	39.06	1.00e-98	352.00
IUUC-Tme-127063	Tuber melanosporum	45.31	6.00e-99	352.00
IUUC-Tbe-127342	Tupaia belangeri	36.25	2.00e-50	191.00
IUUC-Ttr-128381	Tursiops truncatus	45.31	4.00e-86	309.00
IUUC-Uma-129504	Ustilago maydis	38.57	8.00e-102	362.00
IUUC-Vda-129930	Verticillium dahliae	42.41	1.00e-95	341.00
IUUC-Vvi-130851	Vitis vinifera	40.30	3.00e-91	327.00
IUUC-Xtr-131772	Xenopus tropicalis	36.41	6.00e-56	209.00
IUUC-Xma-133802	Xiphophorus maculatus	38.72	3.00e-111	393.00
IUUC-Yli-134331	Yarrowia lipolytica	51.71	1.00e-60	225.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence