iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Eca-033591

Ensembl Protein ID

ENSECAP00000009434.1

UniProt Accession

F7BGP4; F7BGP4_HORSE

Protein Name

Histone-lysine N-methyltransferase

Gene Name

NSD1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000011291.1	ENSECAT00000012000.1	ENSECAP00000009434.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.30e-14	54.3	1400	1440

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           +C vC egg+    l++C+ C  +fH +Cl++      p+ + w+C++C+
   Q: 1400 WCFVCSEGGS----LLCCDSCPAAFHRECLNID----IPEGN-WYCNDCK 1440
           8*********....*******************....99996.******8 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

CQPKKKSTPL KYEVGDLIWA KFKRRPWWPC RICSDPLINT HSKMKVSNRR PYRQYYVEAF 60
GDPSERAWVA GKAIVMFEGR HQFEELPVLR RRGKQKEKGY RHKVPQKILS KWEASVGLAE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGTCAACCCA AGAAAAAGTC TACGCCGCTG AAGTACGAAG TTGGAGATCT CATCTGGGCA 60
AAATTCAAGA GACGCCCATG GTGGCCCTGC AGGATTTGTT CTGATCCATT GATTAACACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR006560--AWS_dom
IPR003616--Post-SET_dom
IPR000313--PWWP_dom
IPR001214--SET_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51215--AWS
PS50868--POST_SET
PS50812--PWWP
PS50280--SET
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF00855--PWWP
PF00856--SET

SMART

SM00570--AWS
SM00249--PHD
SM00508--PostSET
SM00293--PWWP
SM00317--SET

Gene Ontology

GO:0005634--C:nucleus
GO:0018024--F:histone-lysine N-methyltransferase activity
GO:0008270--F:zinc ion binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001795	Ailuropoda melanoleuca	93.02	0.00e+00	4346.00
IUUC-Apl-003953	Anas platyrhynchos	57.91	0.00e+00	2282.00
IUUC-Aca-005339	Anolis carolinensis	51.05	0.00e+00	1795.00
IUUC-Bta-012966	Bos taurus	92.85	0.00e+00	4378.00
IUUC-Bdi-014781	Brachypodium distachyon	28.64	4.00e-12	66.60
IUUC-Bol-016001	Brassica oleracea	28.42	1.00e-15	79.30
IUUC-Bra-017864	Brassica rapa	27.87	2.00e-14	75.50
IUUC-Cja-018780	Callithrix jacchus	89.66	0.00e+00	3895.00
IUUC-Cfa-020975	Canis familiaris	92.47	0.00e+00	4323.00
IUUC-Cpo-021331	Cavia porcellus	87.55	0.00e+00	2685.00
IUUC-Csa-024226	Chlorocebus sabaeus	90.41	0.00e+00	4154.00
IUUC-Cho-024464	Choloepus hoffmanni	77.43	0.00e+00	1426.00
IUUC-Dre-028152	Danio rerio	62.96	0.00e+00	1256.00
IUUC-Dno-029230	Dasypus novemcinctus	87.69	0.00e+00	4031.00
IUUC-Dor-031016	Dipodomys ordii	81.06	0.00e+00	1321.00
IUUC-Dme-032193	Drosophila melanogaster	35.36	1.00e-123	437.00
IUUC-Fca-035791	Felis catus	92.93	0.00e+00	4467.00
IUUC-Fal-037378	Ficedula albicollis	58.52	0.00e+00	2092.00
IUUC-Gmo-038919	Gadus morhua	71.36	0.00e+00	946.00
IUUC-Gga-040881	Gallus gallus	57.06	0.00e+00	2195.00
IUUC-Gac-041378	Gasterosteus aculeatus	77.54	0.00e+00	1071.00
IUUC-Hsa-046436	Homo sapiens	90.62	0.00e+00	4186.00
IUUC-Itr-048194	Ictidomys tridecemlineatus	88.94	0.00e+00	4211.00
IUUC-Lch-049684	Latimeria chalumnae	50.57	0.00e+00	1597.00
IUUC-Lpe-051661	Leersia perrieri	28.72	5.00e-12	67.00
IUUC-Laf-054046	Loxodonta africana	89.79	0.00e+00	4146.00
IUUC-Mcc-055593	Macaca mulatta	90.29	0.00e+00	4153.00
IUUC-Mga-059756	Meleagris gallopavo	57.35	0.00e+00	2270.00
IUUC-Mmr-061182	Microcebus murinus	89.74	0.00e+00	4236.00
IUUC-Mdo-061984	Monodelphis domestica	68.18	0.00e+00	2996.00
IUUC-Mmu-063605	Mus musculus	82.74	0.00e+00	3860.00
IUUC-Mpu-066446	Mustela putorius furo	92.89	0.00e+00	4403.00
IUUC-Mlu-067261	Myotis lucifugus	90.90	0.00e+00	4231.00
IUUC-Nle-069818	Nomascus leucogenys	90.33	0.00e+00	4189.00
IUUC-Opr-070842	Ochotona princeps	83.93	0.00e+00	2368.00
IUUC-Ont-072448	Oreochromis niloticus	66.29	0.00e+00	1157.00
IUUC-Oan-073496	Ornithorhynchus anatinus	71.55	0.00e+00	1659.00
IUUC-Ocu-074918	Oryctolagus cuniculus	89.89	0.00e+00	4276.00
IUUC-Obr-076753	Oryza brachyantha	54.84	9.00e-08	53.50
IUUC-Ola-087518	Oryzias latipes	76.54	0.00e+00	1063.00
IUUC-Oga-088743	Otolemur garnettii	88.80	0.00e+00	4095.00
IUUC-Oar-090265	Ovis aries	92.35	0.00e+00	4356.00
IUUC-Ptr-090521	Pan troglodytes	90.67	0.00e+00	4202.00
IUUC-Psi-093245	Pelodiscus sinensis	59.53	0.00e+00	2064.00
IUUC-Pfo-096066	Poecilia formosa	62.49	0.00e+00	1227.00
IUUC-Pab-098644	Pongo abelii	90.12	0.00e+00	4159.00
IUUC-Pva-103094	Pteropus vampyrus	89.95	0.00e+00	2232.00
IUUC-Rno-105803	Rattus norvegicus	83.05	0.00e+00	3856.00
IUUC-Sha-107278	Sarcophilus harrisii	69.30	0.00e+00	3047.00
IUUC-Sar-113402	Sorex araneus	79.33	0.00e+00	2588.00
IUUC-Sbi-114400	Sorghum bicolor	36.54	4.00e-13	66.60
IUUC-Ssc-116193	Sus scrofa	92.36	0.00e+00	4242.00
IUUC-Tgu-116532	Taeniopygia guttata	89.55	0.00e+00	1257.00
IUUC-Tru-117988	Takifugu rubripes	78.19	0.00e+00	1202.00
IUUC-Tsy-118830	Tarsius syrichta	89.59	0.00e+00	3667.00
IUUC-Tca-121456	Theobroma cacao	30.33	1.00e-19	91.70
IUUC-Xma-133606	Xiphophorus maculatus	76.95	0.00e+00	1145.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence