iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-005204

UUCD1 version

UUC-AnC-00592

Ensembl Protein ID

ENSACAP00000006362.3

UniProt Accession

G1KFF7; G1KFF7_ANOCA

Protein Name

Uncharacterized protein

Gene Name

CBLB

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000006453.3	ENSACAT00000006504.3	ENSACAP00000006362.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	7.40e-08	32.7	373	412

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C iC e  kd +++ pCgH+++++Cl +w    ++s ++  CP Cr
   Q: 373  CKICAENDKD-VKIEPCGHLMCTSCLTAW----QESDGQ-GCPFCR 412
           99********.******************....555555.5****8 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MANSLNGRNP GGRGGNPRKG RILGFIDAIQ DAVGPPKQAA ADRRTVEKTW KLMDKVVRLC 60
QNPKLQLKNS PPYILDILPD TYQHLRLILS KYDDNQKLAQ LSENEYFKIY IDSLMKKSKR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCCAGAACC AACAAACACA AACAAAAAAA ACCTACCGAA AGAGGAGGCG GGAACAGCGA 60
CCAATCCCAC CTCACTCTCT CTCCCCCTCC TCCCCCCCCC CCCCCGCTTT TTCAGTCGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR024162--Adaptor_Cbl
IPR014741--Adaptor_Cbl_EF_hand-like
IPR003153--Adaptor_Cbl_N_hlx
IPR014742--Adaptor_Cbl_SH2-like
IPR024159--Cbl_PTB
IPR011992--EF-hand-dom_pair
IPR000980--SH2
IPR015940--UBA
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51506--CBL_PTB
PS50030--UBA
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF02262--Cbl_N
PF02761--Cbl_N2
PF02762--Cbl_N3

SMART

SM00184--RING
SM00165--UBA

Gene Ontology

GO:0005829--C:cytosol
GO:0045121--C:membrane raft
GO:0005654--C:nucleoplasm
GO:0005886--C:plasma membrane
GO:0005509--F:calcium ion binding
GO:0030971--F:receptor tyrosine kinase binding
GO:0017124--F:SH3 domain binding
GO:0004871--F:signal transducer activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0007173--P:epidermal growth factor receptor signaling pathway
GO:0007175--P:negative regulation of epidermal growth factor-activated receptor activity
GO:0006508--P:proteolysis

KEGG

acs:100561034

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001412	Ailuropoda melanoleuca	82.88	0.00e+00	1403.00
IUUC-Apl-004148	Anas platyrhynchos	84.01	0.00e+00	1456.00
IUUC-Ame-011919	Astyanax mexicanus	63.66	0.00e+00	993.00
IUUC-Bta-013044	Bos taurus	83.08	0.00e+00	1401.00
IUUC-Cel-018674	Caenorhabditis elegans	56.92	8.00e-134	470.00
IUUC-Cja-018813	Callithrix jacchus	75.33	0.00e+00	1289.00
IUUC-Cfa-021054	Canis familiaris	82.78	0.00e+00	1443.00
IUUC-Cpo-022514	Cavia porcellus	78.72	0.00e+00	1394.00
IUUC-Csa-024110	Chlorocebus sabaeus	82.78	0.00e+00	1417.00
IUUC-Cho-024886	Choloepus hoffmanni	67.75	0.00e+00	957.00
IUUC-Cin-025574	Ciona intestinalis	68.63	5.00e-174	603.00
IUUC-Dre-027480	Danio rerio	65.38	0.00e+00	1049.00
IUUC-Dno-028923	Dasypus novemcinctus	82.17	0.00e+00	1409.00
IUUC-Dor-031040	Dipodomys ordii	87.21	0.00e+00	790.00
IUUC-Dme-032213	Drosophila melanogaster	72.68	0.00e+00	638.00
IUUC-Ete-032406	Echinops telfairi	78.84	0.00e+00	1282.00
IUUC-Eca-033849	Equus caballus	81.97	0.00e+00	1418.00
IUUC-Fca-036224	Felis catus	82.69	0.00e+00	1418.00
IUUC-Fal-036860	Ficedula albicollis	97.43	0.00e+00	992.00
IUUC-Gga-040159	Gallus gallus	81.10	0.00e+00	1401.00
IUUC-Gac-042312	Gasterosteus aculeatus	84.16	0.00e+00	862.00
IUUC-Ggo-045175	Gorilla gorilla	75.58	0.00e+00	1285.00
IUUC-Hsa-046306	Homo sapiens	82.67	0.00e+00	1416.00
IUUC-Lch-049931	Latimeria chalumnae	59.02	0.00e+00	839.00
IUUC-Loc-052524	Lepisosteus oculatus	68.43	0.00e+00	1090.00
IUUC-Laf-053635	Loxodonta africana	79.94	0.00e+00	1355.00
IUUC-Mcc-055536	Macaca mulatta	82.67	0.00e+00	1415.00
IUUC-Meu-056045	Macropus eugenii	70.60	0.00e+00	1135.00
IUUC-Mga-060177	Meleagris gallopavo	92.48	0.00e+00	1085.00
IUUC-Mmr-061088	Microcebus murinus	83.08	0.00e+00	1425.00
IUUC-Mdo-062020	Monodelphis domestica	83.95	0.00e+00	1420.00
IUUC-Mmu-063114	Mus musculus	80.12	0.00e+00	1383.00
IUUC-Mpu-066632	Mustela putorius furo	83.38	0.00e+00	1450.00
IUUC-Mlu-067145	Myotis lucifugus	82.78	0.00e+00	1421.00
IUUC-Ont-072323	Oreochromis niloticus	73.27	0.00e+00	868.00
IUUC-Oan-073165	Ornithorhynchus anatinus	83.11	0.00e+00	1475.00
IUUC-Ocu-074723	Oryctolagus cuniculus	83.28	0.00e+00	1438.00
IUUC-Oga-088021	Otolemur garnettii	82.17	0.00e+00	1413.00
IUUC-Oar-089809	Ovis aries	83.28	0.00e+00	1407.00
IUUC-Ptr-090834	Pan troglodytes	82.57	0.00e+00	1413.00
IUUC-Pan-092225	Papio anubis	82.88	0.00e+00	1421.00
IUUC-Psi-093317	Pelodiscus sinensis	85.73	0.00e+00	1534.00
IUUC-Pma-094249	Petromyzon marinus	77.61	8.00e-127	446.00
IUUC-Pab-097595	Pongo abelii	82.67	0.00e+00	1415.00
IUUC-Pca-100844	Procavia capensis	69.71	0.00e+00	1100.00
IUUC-Pva-103216	Pteropus vampyrus	77.13	0.00e+00	1351.00
IUUC-Rno-105381	Rattus norvegicus	82.07	0.00e+00	1431.00
IUUC-Sha-107574	Sarcophilus harrisii	83.49	0.00e+00	1413.00
IUUC-Sar-113500	Sorex araneus	71.85	0.00e+00	1145.00
IUUC-Ssc-115856	Sus scrofa	80.26	0.00e+00	1189.00
IUUC-Tgu-116866	Taeniopygia guttata	83.07	0.00e+00	1428.00
IUUC-Tru-118579	Takifugu rubripes	85.14	0.00e+00	879.00
IUUC-Tsy-119167	Tarsius syrichta	81.58	0.00e+00	990.00
IUUC-Tni-120788	Tetraodon nigroviridis	85.33	0.00e+00	874.00
IUUC-Tbe-127830	Tupaia belangeri	88.01	0.00e+00	1071.00
IUUC-Ttr-128631	Tursiops truncatus	83.18	0.00e+00	1427.00
IUUC-Vpa-130713	Vicugna pacos	83.53	0.00e+00	1253.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence