iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSRNOG00000001769.7	ENSRNOT00000084768.1	ENSRNOP00000070836.1
ENSRNOG00000001769.7	ENSRNOT00000002411.7	ENSRNOP00000002411.4

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	TRANSFAC	RAID2
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UBA	97.82	0.00e+00	1842.00	IUUC-Mmu-063861

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MQPEEGTGWL LELLSEVQLQ QYFLRLRDDL NITRLSHFEY VKNEDLEKIG MGRPGQRRLW 60
EAVKRRKAMC KRKSWMSKVF SGKRQEAEFP SHHSQSTFRK PSPTPGGLAG EGTLQSLTCL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTCCCCAGCG GGAGAGGGAT TCCAAGAGGG ACACAGAACC CGCAGGCGCA GACGACGAAG 60
GAGGTGGTAA TCTGCAAGCT GCCTTACTGG CATCGGGGTT GCTCTAGTGC CAAGAGGAAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR015116--Cdc42_binding_dom-like
IPR011009--Kinase-like_dom
IPR021619--Mig-6
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50002--SH3

Pfam

PF09027--GTPase_binding
PF11555--Inhibitor_Mig-6
PF07714--Pkinase_Tyr
PF14604--SH3_9

PRINTS

PR00109--TYRKINASE

SMART

SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005905--C:clathrin-coated pit
GO:0030136--C:clathrin-coated vesicle
GO:0070436--C:Grb2-EGFR complex
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0004712--F:protein serine/threonine/tyrosine kinase activity
GO:0004713--F:protein tyrosine kinase activity
GO:0050731--P:positive regulation of peptidyl-tyrosine phosphorylation
GO:2000369--P:regulation of clathrin-dependent endocytosis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002166	Ailuropoda melanoleuca	91.96	0.00e+00	1667.00
IUUC-Aca-004315	Anolis carolinensis	88.97	1.00e-73	268.00
IUUC-Ame-011350	Astyanax mexicanus	54.87	0.00e+00	1033.00
IUUC-Bta-012325	Bos taurus	92.51	0.00e+00	1729.00
IUUC-Cel-018130	Caenorhabditis elegans	36.67	2.00e-89	324.00
IUUC-Cja-019545	Callithrix jacchus	86.84	0.00e+00	1568.00
IUUC-Cfa-020706	Canis familiaris	92.90	0.00e+00	1744.00
IUUC-Cpo-022032	Cavia porcellus	89.94	0.00e+00	1690.00
IUUC-Csa-023936	Chlorocebus sabaeus	94.31	0.00e+00	1736.00
IUUC-Csv-026328	Ciona savignyi	59.24	1.00e-173	602.00
IUUC-Dre-028714	Danio rerio	63.86	0.00e+00	1215.00
IUUC-Dno-029525	Dasypus novemcinctus	92.23	0.00e+00	1730.00
IUUC-Dme-031778	Drosophila melanogaster	56.57	1.00e-144	508.00
IUUC-Ete-032225	Echinops telfairi	89.76	0.00e+00	850.00
IUUC-Fca-035664	Felis catus	92.90	0.00e+00	1790.00
IUUC-Gmo-039543	Gadus morhua	58.54	0.00e+00	922.00
IUUC-Gga-040241	Gallus gallus	67.63	0.00e+00	1302.00
IUUC-Gac-041457	Gasterosteus aculeatus	62.98	0.00e+00	1123.00
IUUC-Ggo-045333	Gorilla gorilla	91.75	0.00e+00	1705.00
IUUC-Hsa-046670	Homo sapiens	92.51	0.00e+00	1675.00
IUUC-Itr-048054	Ictidomys tridecemlineatus	94.59	0.00e+00	1788.00
IUUC-Lch-049670	Latimeria chalumnae	63.07	0.00e+00	1192.00
IUUC-Loc-052870	Lepisosteus oculatus	64.34	0.00e+00	1259.00
IUUC-Laf-053782	Loxodonta africana	91.27	0.00e+00	1686.00
IUUC-Mcc-055874	Macaca mulatta	94.31	0.00e+00	1724.00
IUUC-Mga-059717	Meleagris gallopavo	70.60	0.00e+00	1368.00
IUUC-Mdo-062270	Monodelphis domestica	85.63	0.00e+00	1614.00
IUUC-Mmu-063861	Mus musculus	97.82	0.00e+00	1873.00
IUUC-Mpu-066127	Mustela putorius furo	95.64	0.00e+00	1367.00
IUUC-Mlu-067937	Myotis lucifugus	90.27	0.00e+00	1330.00
IUUC-Nle-069298	Nomascus leucogenys	91.36	0.00e+00	1392.00
IUUC-Ont-072437	Oreochromis niloticus	58.09	0.00e+00	1155.00
IUUC-Oan-073708	Ornithorhynchus anatinus	75.00	3.00e-115	409.00
IUUC-Ola-087023	Oryzias latipes	62.00	0.00e+00	1151.00
IUUC-Pan-091857	Papio anubis	91.15	3.00e-93	334.00
IUUC-Psi-093401	Pelodiscus sinensis	54.95	9.00e-149	520.00
IUUC-Pfo-097455	Poecilia formosa	59.62	0.00e+00	1192.00
IUUC-Sha-106868	Sarcophilus harrisii	88.09	0.00e+00	1291.00
IUUC-Ssc-116250	Sus scrofa	91.86	0.00e+00	1659.00
IUUC-Tgu-116592	Taeniopygia guttata	70.14	0.00e+00	1299.00
IUUC-Tru-117852	Takifugu rubripes	70.25	1.00e-180	627.00
IUUC-Tsy-119087	Tarsius syrichta	98.51	1.00e-158	554.00
IUUC-Tni-120826	Tetraodon nigroviridis	63.32	0.00e+00	1223.00
IUUC-Xtr-132069	Xenopus tropicalis	65.41	0.00e+00	1184.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence