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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Mmu-064075
Ensembl Protein ID ENSMUSP00000117066.1
UniProt Accession E9Q2N1; E9Q2N1_MOUSE
Genbank Protein ID ENSMUSP00000117066
Protein Name Bromodomain and WD repeat-containing protein 1
Genbank Nucleotide ID AC144797
Gene Name Brwd1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000022914.15 ENSMUST00000023631.14 ENSMUSP00000023631.8
ENSMUSG00000022914.15 ENSMUST00000113829.7 ENSMUSP00000109460.1
ENSMUSG00000022914.15 ENSMUST00000153398.7 ENSMUSP00000117066.1
ENSMUSG00000022914.15 ENSMUST00000131322.7 ENSMUSP00000118327.1
ENSMUSG00000022914.15 ENSMUST00000152197.2 ENSMUSP00000122457.1
ENSMUSG00000022914.15 ENSMUST00000124370.7 ENSMUSP00000118423.1
ENSMUSG00000022914.15 ENSMUST00000139566.1 ENSMUSP00000121141.1
ENSMUSG00000022914.15 ENSMUST00000113827.1 ENSMUSP00000109458.1
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
AREsitemiRTarBasemicroRNATRANSFAC
RepTarRAID2
Post-translational Modifications (PTMs)
PHOSIDA
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 3.10e-34 116.6 184 221
UBD/Beta-Prp 1.40e-53 183.1 329 543
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           gH + v+c+af  + +++ +GsdD+ +k+W+++ g+ll
   Q: 184  GHLSAVYCVAFdRTgHRIFTGSDDCLVKIWSTHNGRLL 221
           8**********955599***************999987 PP
   

   UBD/Beta-Prp
   S: 57   avkfspdgkilvtgseDrtikvw..dlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee............ 131
           + +fs  g +l+tgs+D++i+ +   +++++ +  l+ h+d+v s++f+ +gd+++sGs+d t+r+w  e+ ++ +             
   Q: 329  CSSFSVGGMFLATGSTDHVIRMYflGFDAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSIlldmsarisgdt 417
           667888999**************99999*******************************************999988999********8 PP
   S: 132  ...tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvysls...fdsngkelvsgsldgtvklwdlqtgec 214
               ++  +  v+++++++d++ +v++ +D ++++W++ tg+ll+ l g h d v  l+   fds  + ++s+++dg++ +wd+ +g  
   Q: 418  sseEERFMKPKVTMIAWNQDDSTVVTAVNDHVLKVWSSYTGQLLHNLLG-HADEVFVLEthpFDS--RIMLSAGHDGSIFIWDITKGIK 503
           777666667789************************************9.*********555555..99****************8877 PP
   S: 215  vrtlnght.....dnvksvrfspnderlvsgssDgsiriW 249
           ++ + +         v + +fs+++++++++ s+g + i+
   Q: 504  MKHYFNMIegqghGAVFDCKFSQDGQHFACTDSHGHLLIF 543
           5555443333334667778999999999999999998876 PP
   
Organism Mus musculus
Protein Sequence
(Fasta)
MAEPSPARRP VPLIESELYF LIARYLSAGP CRRAAQVLVQ ELEQYQLLPK RLDWEGNEHN 60
RSYEELVLSN KHVAPDHLLQ ICQRIGPMLD KEVPPSISRV TSLLGAGRQS LLRTAKDCRH 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-064075|E3,WD_repeat;UBD,Beta-Prp|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GCGTCGTGCC ACGCCGCCGG CTCCCCGCGG GGGGACTACT TCGCTCCCCG CCCCTCGGTC 60
CCGCGCGACT TCCTGCCGCG GACGCGTCGG TGCGCGGCGC GCACGGCATG GCGGCGGCGG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-064075|E3,WD_repeat;UBD,Beta-Prp|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0853--WD repeat
Interpro

IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF00439--Bromodomain
PF00400--WD40
PRINTS

PR00503--BROMODOMAIN
SMART

SM00297--BROMO
SM00320--WD40
Gene Ontology

GO:0005634--C:nucleus
GO:0006357--P:regulation of transcription from RNA polymerase II promoter
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002332 Ailuropoda melanoleuca 81.11 0.00e+00 2759.00
IUUC-Apl-004083 Anas platyrhynchos 67.55 0.00e+00 1931.00
IUUC-Aca-004348 Anolis carolinensis 70.32 0.00e+00 1894.00
IUUC-Aly-006517 Arabidopsis lyrata 30.58 7.00e-73 270.00
IUUC-Bta-013217 Bos taurus 80.69 0.00e+00 2853.00
IUUC-Bol-015737 Brassica oleracea 29.91 6.00e-74 273.00
IUUC-Bra-017961 Brassica rapa 30.01 5.00e-74 273.00
IUUC-Cja-019966 Callithrix jacchus 82.35 0.00e+00 2956.00
IUUC-Cfa-021037 Canis familiaris 81.23 0.00e+00 2874.00
IUUC-Cpo-021934 Cavia porcellus 89.00 0.00e+00 2691.00
IUUC-Cre-023003 Chlamydomonas reinhardtii 35.56 2.00e-34 141.00
IUUC-Csa-023352 Chlorocebus sabaeus 81.49 0.00e+00 2676.00
IUUC-Cho-024690 Choloepus hoffmanni 95.73 0.00e+00 748.00
IUUC-Dno-028938 Dasypus novemcinctus 77.97 0.00e+00 2788.00
IUUC-Dme-031752 Drosophila melanogaster 49.59 0.00e+00 672.00
IUUC-Eca-034349 Equus caballus 85.14 0.00e+00 2713.00
IUUC-Fca-035485 Felis catus 80.09 0.00e+00 2790.00
IUUC-Fal-037307 Ficedula albicollis 68.30 0.00e+00 2322.00
IUUC-Gga-040865 Gallus gallus 75.45 0.00e+00 2279.00
IUUC-Gma-044324 Glycine max 30.76 4.00e-70 260.00
IUUC-Ggo-045500 Gorilla gorilla 82.53 0.00e+00 2914.00
IUUC-Hsa-046350 Homo sapiens 82.32 0.00e+00 2935.00
IUUC-Itr-047962 Ictidomys tridecemlineatus 88.73 0.00e+00 1094.00
IUUC-Lch-049662 Latimeria chalumnae 65.19 0.00e+00 2070.00
IUUC-Lpe-051619 Leersia perrieri 31.31 6.00e-70 260.00
IUUC-Loc-052853 Lepisosteus oculatus 66.93 0.00e+00 1846.00
IUUC-Laf-053848 Loxodonta africana 80.47 0.00e+00 2836.00
IUUC-Mcc-054638 Macaca mulatta 82.68 0.00e+00 2931.00
IUUC-Meu-056739 Macropus eugenii 78.63 0.00e+00 1100.00
IUUC-Mga-060165 Meleagris gallopavo 75.90 0.00e+00 2268.00
IUUC-Mmr-061227 Microcebus murinus 82.93 0.00e+00 2966.00
IUUC-Mac-065343 Musa acuminata 30.53 8.00e-76 279.00
IUUC-Mpu-066643 Mustela putorius furo 82.30 0.00e+00 2697.00
IUUC-Mlu-067735 Myotis lucifugus 79.63 0.00e+00 2773.00
IUUC-Nle-069402 Nomascus leucogenys 88.41 0.00e+00 2774.00
IUUC-Ont-072298 Oreochromis niloticus 63.66 0.00e+00 1847.00
IUUC-Oan-072954 Ornithorhynchus anatinus 72.75 0.00e+00 2600.00
IUUC-Ocu-074456 Oryctolagus cuniculus 81.89 0.00e+00 2964.00
IUUC-Oba-075709 Oryza barthii 30.68 1.00e-60 229.00
IUUC-Oru-085195 Oryza rufipogon 30.68 2.00e-60 228.00
IUUC-Olu-087745 Ostreococcus lucimarinus 28.44 2.00e-56 214.00
IUUC-Oga-087938 Otolemur garnettii 75.48 0.00e+00 2670.00
IUUC-Oar-090214 Ovis aries 79.85 0.00e+00 2717.00
IUUC-Ptr-091213 Pan troglodytes 82.63 0.00e+00 2934.00
IUUC-Pan-092444 Papio anubis 82.23 0.00e+00 2913.00
IUUC-Psi-093271 Pelodiscus sinensis 63.58 0.00e+00 2086.00
IUUC-Pma-094427 Petromyzon marinus 66.98 6.00e-131 460.00
IUUC-Ppa-095793 Physcomitrella patens 29.53 3.00e-73 271.00
IUUC-Pfo-097318 Poecilia formosa 63.15 0.00e+00 1794.00
IUUC-Pab-097573 Pongo abelii 80.49 0.00e+00 2831.00
IUUC-Ppe-101849 Prunus persica 30.98 7.00e-76 280.00
IUUC-Pva-102782 Pteropus vampyrus 81.67 0.00e+00 2828.00
IUUC-Rno-105687 Rattus norvegicus 94.02 0.00e+00 3442.00
IUUC-Sly-111348 Solanum lycopersicum 30.85 2.00e-75 278.00
IUUC-Sar-113519 Sorex araneus 78.21 0.00e+00 1716.00
IUUC-Tgu-116513 Taeniopygia guttata 75.47 0.00e+00 2258.00
IUUC-Tru-117824 Takifugu rubripes 56.36 0.00e+00 1693.00
IUUC-Tsy-118921 Tarsius syrichta 85.51 0.00e+00 1966.00
IUUC-Tni-120656 Tetraodon nigroviridis 57.62 0.00e+00 1631.00
IUUC-Tca-121615 Theobroma cacao 30.86 3.00e-68 254.00
IUUC-Tbe-127663 Tupaia belangeri 81.73 0.00e+00 1168.00
IUUC-Ttr-128561 Tursiops truncatus 79.12 0.00e+00 2686.00
IUUC-Vpa-130444 Vicugna pacos 77.09 0.00e+00 2527.00
Created Date 25-Jun-2017

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