iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fca-036494

Ensembl Protein ID

ENSFCAP00000003134.3

UniProt Accession

M3W0A0; M3W0A0_FELCA

Genbank Protein ID

ENSFCAP00000003134

Protein Name

Coronin

Genbank Nucleotide ID

AANG02012233

Gene Name

CORO1B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000003396.3	ENSFCAT00000003396.3	ENSFCAP00000003134.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.90e-15	54.6	80	111

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtllvsGsdDgtikvWD 29
           gHt++v ++++   +d  ++sGs D+t++vW 
   Q: 80   GHTGPVLDIDWcphNDEVIASGSEDCTVMVWQ 111
           8***********977799*************7 PP

Organism

Felis catus

Protein Sequence
(Fasta)

MSFRKVVRQS KFRHVFGQPV KNDQCYEDIR VSRVTWDSTF CAVNPKFLAV IVEASGGGAF 60
LVLPLSKTGR IDKAYPTVCG HTGPVLDIDW CPHNDEVIAS GSEDCTVMVW QIPENGLASP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

NNCCCCCCGC CCCCTGCCCC CGGCTCCTCT GTCACTTCCT GATTCCCGCT TCCTGCTTCC 60
CAGAGGCCGG GATCCGGAGC CGCCCGAGGC CGGTGCCGCA GTCCCCGGCG TCCCCGGTGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR015505--Coronin
IPR015048--DUF1899
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08953--DUF1899
PF00400--WD40

SMART

SM01166--DUF1899
SM00320--WD40

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0005884--C:actin filament
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0005925--C:focal adhesion
GO:0030027--C:lamellipodium
GO:0048471--C:perinuclear region of cytoplasm
GO:0005886--C:plasma membrane
GO:0001725--C:stress fiber
GO:0051015--F:actin filament binding
GO:0030036--P:actin cytoskeleton organization
GO:0090135--P:actin filament branching
GO:0051017--P:actin filament bundle assembly
GO:0036120--P:cellular response to platelet-derived growth factor stimulus
GO:0035767--P:endothelial cell chemotaxis
GO:0034316--P:negative regulation of Arp2/3 complex-mediated actin nucleation
GO:0071672--P:negative regulation of smooth muscle cell chemotaxis
GO:2000394--P:positive regulation of lamellipodium morphogenesis
GO:1902463--P:protein localization to cell leading edge
GO:0031529--P:ruffle organization
GO:0042060--P:wound healing

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002423	Ailuropoda melanoleuca	95.91	0.00e+00	948.00
IUUC-Aca-005056	Anolis carolinensis	80.82	0.00e+00	815.00
IUUC-Bta-012984	Bos taurus	93.43	0.00e+00	926.00
IUUC-Cja-019498	Callithrix jacchus	93.88	0.00e+00	918.00
IUUC-Cfa-020937	Canis familiaris	96.37	0.00e+00	881.00
IUUC-Cpo-021866	Cavia porcellus	88.14	0.00e+00	880.00
IUUC-Csa-023561	Chlorocebus sabaeus	93.05	0.00e+00	923.00
IUUC-Dno-029770	Dasypus novemcinctus	87.35	0.00e+00	863.00
IUUC-Dor-030989	Dipodomys ordii	92.84	0.00e+00	893.00
IUUC-Eca-033901	Equus caballus	95.09	0.00e+00	919.00
IUUC-Fal-036737	Ficedula albicollis	82.79	0.00e+00	832.00
IUUC-Ggo-045035	Gorilla gorilla	94.48	0.00e+00	929.00
IUUC-Hsa-046154	Homo sapiens	93.87	0.00e+00	922.00
IUUC-Itr-048847	Ictidomys tridecemlineatus	93.46	0.00e+00	889.00
IUUC-Laf-054566	Loxodonta africana	92.84	0.00e+00	895.00
IUUC-Mcc-054879	Macaca mulatta	93.25	0.00e+00	923.00
IUUC-Mmr-060910	Microcebus murinus	93.66	0.00e+00	920.00
IUUC-Mmu-063455	Mus musculus	94.06	0.00e+00	923.00
IUUC-Mpu-066350	Mustela putorius furo	95.30	0.00e+00	918.00
IUUC-Mlu-067353	Myotis lucifugus	94.86	0.00e+00	912.00
IUUC-Nle-069161	Nomascus leucogenys	94.07	0.00e+00	920.00
IUUC-Opr-071106	Ochotona princeps	91.41	0.00e+00	888.00
IUUC-Oga-088805	Otolemur garnettii	92.64	0.00e+00	924.00
IUUC-Ptr-091484	Pan troglodytes	93.87	0.00e+00	923.00
IUUC-Pan-091843	Papio anubis	93.05	0.00e+00	915.00
IUUC-Pab-097835	Pongo abelii	94.27	0.00e+00	926.00
IUUC-Pca-100411	Procavia capensis	81.60	0.00e+00	787.00
IUUC-Pva-102659	Pteropus vampyrus	96.52	0.00e+00	928.00
IUUC-Rno-106070	Rattus norvegicus	92.21	0.00e+00	910.00
IUUC-Sha-106609	Sarcophilus harrisii	94.08	0.00e+00	710.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence