iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062785

UUCD1 version

UUC-MoD-00017

Ensembl Protein ID

ENSMODP00000026469.2

UniProt Accession

H9H7W1; H9H7W1_MONDO

Protein Name

Uncharacterized protein

Gene Name

KLHL4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000021177.3	ENSMODT00000026942.3	ENSMODP00000026469.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	9.10e-19	67.8	43	110
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	2.20e-06	27.0	142	172

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkldene 69
           +Dv l+ g+ +++ah++vL+a+S++F a+f+++  e k ++++++++++p++++al+++ Ytg l+++e
   Q: 43   CDVFLIAGQHKIPAHRLVLSAASDYFAAMFTNDVLEAK-QEEIKMEGIDPDALKALVRYAYTGVLELKE 110
           8************************************9.**************************9986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhF 31
           ++Nclgi++f+d+ +c  L ++a++++  hF
   Q: 142  PSNCLGIRSFGDAQGCLNLLKVAHNYTMEHF 172
           89************************98888 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

LPVNNYSALE MSAGRSEEYF HSTNHAEQTI RKMENYLQHK QLCDVFLIAG QHKIPAHRLV 60
LSAASDYFAA MFTNDVLEAK QEEIKMEGID PDALKALVRY AYTGVLELKE DTIENLLSAA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGGCTATCGC ATGAGCTCGT GCACACCTCT TCCTCCTCCA CCCTCGACGG CCATTTTCTG 60
AAAGGACTCT CCTGAGGAAA AATTAGTGAT TTAAGTTCAC TATCTGCCAG AATATTCCAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015916--Gal_Oxidase_b-propeller
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005815--C:microtubule organizing center
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001422	Ailuropoda melanoleuca	84.75	0.00e+00	944.00
IUUC-Apl-004156	Anas platyrhynchos	90.66	0.00e+00	1048.00
IUUC-Aca-004238	Anolis carolinensis	89.01	0.00e+00	1028.00
IUUC-Afu-008999	Aspergillus fumigatus	26.36	5.00e-05	41.60
IUUC-Ame-011287	Astyanax mexicanus	76.28	0.00e+00	779.00
IUUC-Cja-018916	Callithrix jacchus	85.12	0.00e+00	948.00
IUUC-Cfa-020972	Canis familiaris	83.83	0.00e+00	970.00
IUUC-Csa-023849	Chlorocebus sabaeus	85.61	0.00e+00	984.00
IUUC-Dor-030708	Dipodomys ordii	80.00	0.00e+00	897.00
IUUC-Eca-033542	Equus caballus	83.86	0.00e+00	940.00
IUUC-Fal-036999	Ficedula albicollis	91.65	0.00e+00	1038.00
IUUC-Gmo-039532	Gadus morhua	85.04	0.00e+00	968.00
IUUC-Gga-040215	Gallus gallus	90.50	0.00e+00	1053.00
IUUC-Gac-041582	Gasterosteus aculeatus	84.86	0.00e+00	976.00
IUUC-Ggo-045074	Gorilla gorilla	85.79	0.00e+00	989.00
IUUC-Hsa-046486	Homo sapiens	85.35	0.00e+00	954.00
IUUC-Lch-050265	Latimeria chalumnae	84.80	0.00e+00	996.00
IUUC-Loc-052015	Lepisosteus oculatus	86.26	0.00e+00	996.00
IUUC-Laf-053627	Loxodonta africana	84.56	0.00e+00	982.00
IUUC-Mcc-055418	Macaca mulatta	85.79	0.00e+00	989.00
IUUC-Meu-056859	Macropus eugenii	92.02	2.00e-107	383.00
IUUC-Mga-059582	Meleagris gallopavo	90.67	0.00e+00	1055.00
IUUC-Mmr-061648	Microcebus murinus	84.74	0.00e+00	974.00
IUUC-Mmu-063807	Mus musculus	82.25	0.00e+00	964.00
IUUC-Mpu-066279	Mustela putorius furo	82.32	0.00e+00	963.00
IUUC-Mlu-067981	Myotis lucifugus	82.81	0.00e+00	953.00
IUUC-Ncr-068856	Neurospora crassa	40.74	1.00e-05	43.90
IUUC-Nle-070033	Nomascus leucogenys	85.66	0.00e+00	956.00
IUUC-Ont-071932	Oreochromis niloticus	86.29	0.00e+00	999.00
IUUC-Ola-087436	Oryzias latipes	84.44	0.00e+00	978.00
IUUC-Oar-089952	Ovis aries	84.44	0.00e+00	978.00
IUUC-Pan-091798	Papio anubis	85.96	0.00e+00	990.00
IUUC-Psi-093728	Pelodiscus sinensis	89.98	0.00e+00	1034.00
IUUC-Pfo-096954	Poecilia formosa	85.76	0.00e+00	990.00
IUUC-Pab-098461	Pongo abelii	85.61	0.00e+00	976.00
IUUC-Rno-105865	Rattus norvegicus	83.13	0.00e+00	960.00
IUUC-Sha-107322	Sarcophilus harrisii	92.06	0.00e+00	1081.00
IUUC-Ssc-116001	Sus scrofa	85.69	0.00e+00	980.00
IUUC-Tgu-116994	Taeniopygia guttata	92.36	0.00e+00	1045.00
IUUC-Tru-117780	Takifugu rubripes	85.59	0.00e+00	978.00
IUUC-Tni-120794	Tetraodon nigroviridis	82.47	0.00e+00	951.00
IUUC-Tbe-128118	Tupaia belangeri	64.71	2.00e-176	612.00
IUUC-Xtr-132358	Xenopus tropicalis	86.47	0.00e+00	1000.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence