iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ont-072440

Ensembl Protein ID

ENSONIP00000002471.1

UniProt Accession

I3J0T1; I3J0T1_ORENI

Genbank Protein ID

ENSONIP00000002471

Protein Name

Tyrosine-protein kinase

Genbank Nucleotide ID

AERX01004070

Gene Name

abl2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000001974.1	ENSONIT00000002472.1	ENSONIP00000002471.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	2.90e-12	46.8	107	164

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
            +++ +lyd+ a+ d++L+++kG++++v+  ++q+++W +     ++ +G +P+n+++ ++
   Q: 107  PNLFVALYDFVASGDNTLSITKGEKLRVL-GYNQNGEWSEV--RSKNGQGWVPSNYITPVN 164
           67899************************.*********98..788899*********997 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

MGQQVGRVGE GTSTGLQPPQ PHAPQPHQGK GNRGSGVGRR PREPGSSTGT PPGRTAPVNV 60
PDPGINIFTQ HSVVQRIYAC PFVPEALTEA VRWSSKENLL GAAESDPNLF VALYDFVASG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGACAGC AGGTTGGCCG AGTCGGTGAG GGTACATCGA CCGGGCTCCA GCCACCACAG 60
CCCCACGCGC CCCAACCACA CCAAGGGAAG GGGAACCGGG GGAGCGGCGT CGGGAGGAGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR015015--F-actin_binding
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS50001--SH2
PS50002--SH3

Pfam

PF08919--F_actin_bind
PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00109--TYRKINASE

SMART

SM00808--FABD
SM00252--SH2
SM00326--SH3

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002263	Ailuropoda melanoleuca	66.78	0.00e+00	1363.00
IUUC-Apl-003389	Anas platyrhynchos	66.06	0.00e+00	1310.00
IUUC-Ame-010629	Astyanax mexicanus	65.01	0.00e+00	1197.00
IUUC-Bta-013370	Bos taurus	63.59	0.00e+00	1356.00
IUUC-Cja-018894	Callithrix jacchus	65.94	0.00e+00	1376.00
IUUC-Cfa-020398	Canis familiaris	85.14	0.00e+00	1060.00
IUUC-Cpo-022367	Cavia porcellus	75.99	0.00e+00	1194.00
IUUC-Csa-023386	Chlorocebus sabaeus	66.61	0.00e+00	1359.00
IUUC-Cho-024714	Choloepus hoffmanni	77.76	0.00e+00	1131.00
IUUC-Dre-027741	Danio rerio	76.32	0.00e+00	1591.00
IUUC-Dno-029246	Dasypus novemcinctus	66.50	0.00e+00	1343.00
IUUC-Ete-032899	Echinops telfairi	84.36	1.00e-126	447.00
IUUC-Eca-033387	Equus caballus	66.44	0.00e+00	1346.00
IUUC-Eeu-035058	Erinaceus europaeus	59.65	0.00e+00	1270.00
IUUC-Fca-036578	Felis catus	70.75	0.00e+00	1134.00
IUUC-Fal-037491	Ficedula albicollis	66.52	0.00e+00	1386.00
IUUC-Gmo-038509	Gadus morhua	85.42	0.00e+00	1285.00
IUUC-Gga-040638	Gallus gallus	66.04	0.00e+00	1349.00
IUUC-Gac-042550	Gasterosteus aculeatus	85.14	0.00e+00	1754.00
IUUC-Ggo-044487	Gorilla gorilla	65.27	0.00e+00	1361.00
IUUC-Hsa-046636	Homo sapiens	65.44	0.00e+00	1361.00
IUUC-Itr-048685	Ictidomys tridecemlineatus	66.44	0.00e+00	1355.00
IUUC-Lch-049530	Latimeria chalumnae	73.42	0.00e+00	1295.00
IUUC-Loc-051933	Lepisosteus oculatus	75.97	0.00e+00	1520.00
IUUC-Laf-053802	Loxodonta africana	63.69	0.00e+00	1391.00
IUUC-Mcc-054836	Macaca mulatta	65.50	0.00e+00	1363.00
IUUC-Mga-059277	Meleagris gallopavo	66.52	0.00e+00	1352.00
IUUC-Mmr-061206	Microcebus murinus	63.75	0.00e+00	1316.00
IUUC-Mdo-062281	Monodelphis domestica	84.88	0.00e+00	1067.00
IUUC-Mmu-063847	Mus musculus	65.47	0.00e+00	1337.00
IUUC-Mpu-066309	Mustela putorius furo	78.44	0.00e+00	1073.00
IUUC-Mlu-068070	Myotis lucifugus	66.52	0.00e+00	1353.00
IUUC-Nle-070062	Nomascus leucogenys	82.62	0.00e+00	1063.00
IUUC-Oan-073526	Ornithorhynchus anatinus	72.30	0.00e+00	1257.00
IUUC-Ocu-074051	Oryctolagus cuniculus	66.44	0.00e+00	1319.00
IUUC-Ola-086752	Oryzias latipes	97.01	0.00e+00	922.00
IUUC-Oga-088767	Otolemur garnettii	60.84	0.00e+00	1164.00
IUUC-Oar-089800	Ovis aries	66.35	0.00e+00	1352.00
IUUC-Ptr-090857	Pan troglodytes	82.47	0.00e+00	1062.00
IUUC-Pan-092279	Papio anubis	66.70	0.00e+00	1372.00
IUUC-Psi-093573	Pelodiscus sinensis	72.07	0.00e+00	1209.00
IUUC-Pfo-096543	Poecilia formosa	85.19	0.00e+00	1715.00
IUUC-Pab-097949	Pongo abelii	66.44	0.00e+00	1347.00
IUUC-Pca-100370	Procavia capensis	59.61	0.00e+00	905.00
IUUC-Rno-105924	Rattus norvegicus	63.84	0.00e+00	1338.00
IUUC-Sha-107114	Sarcophilus harrisii	75.06	0.00e+00	1118.00
IUUC-Ssc-115968	Sus scrofa	63.25	0.00e+00	1365.00
IUUC-Tgu-117301	Taeniopygia guttata	73.06	0.00e+00	1271.00
IUUC-Tru-118410	Takifugu rubripes	87.53	0.00e+00	1927.00
IUUC-Tni-119991	Tetraodon nigroviridis	86.14	0.00e+00	1913.00
IUUC-Tbe-127362	Tupaia belangeri	74.82	0.00e+00	1183.00
IUUC-Ttr-129291	Tursiops truncatus	66.55	0.00e+00	1351.00
IUUC-Vpa-130800	Vicugna pacos	76.81	0.00e+00	1186.00
IUUC-Xtr-132965	Xenopus tropicalis	64.24	0.00e+00	1130.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence