iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

mRNA Expression
GEO
DNA & RNA Element
TRANSFAC
Protein-protein Interaction
iRefIndex	HINT	Mentha
Post-translational Modifications (PTMs)
dbPAF	dbPTM
Protein Expression/Proteomics

Status

Reviewed

Details

Family	Domain	References (PMIDs)
DUB/JAMM	JAMM	16056266

Classification

Family	E-value	Score	Start	End
DUB/JAMM	1.50e-08	32.5	112	125

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/JAMM

   S: 1    HSHPgftcwlSsVD 14
           HSHPgf+cwlSsVD
   Q: 112  HSHPGFGCWLSSVD 125
           *************9 PP

Organism

Schizosaccharomyces pombe

Functional Description
(View)

Transcription factor pap1 is controlled by the functional interaction between the positive regulator pad1 and negative regulator crm1. Both these proteins are also essential for cell viability and for the maintenance of chromosome structure. Pad1 is also responsible for resistance to staurosporine, and other drugs such as cycloheximide and caffeine.

Protein Sequence
(Fasta)

MESLQRLLQG ARMGTGMMGD QPLVDNSECV YISSLALLKM LRHGRHGTPM EVMGLMLGEF 60
VDDFTVRVVD VFAMPQSGTG VSVEAVDPVF QKNMMDMLKQ TGRPEMVVGW YHSHPGFGCW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCTAGAAAAA ACCTGTTTAT AGCCAACTAC CACGTAAACG TATACTAGCT GCCTAAGTGA 60
GACCAAAGAC ATAGAATCTT GTATATTCGT TTTGTATAGT GGTTGAAACA TATAGAAAGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0046--Antibiotic resistance
KW-0181--Complete proteome
KW-0196--Cycloheximide resistance
KW-0647--Proteasome
KW-1185--Reference proteome

Interpro

IPR000555--JAMM/MPN+_dom
IPR024969--Rpn11/EIF3F_C

Pfam

PF01398--JAB
PF13012--MitMem_reg

SMART

SM00232--JAB_MPN

Gene Ontology

GO:0005737--C:cytoplasm
GO:0034399--C:nuclear periphery
GO:0031595--C:nuclear proteasome complex
GO:0005634--C:nucleus
GO:0008541--C:proteasome regulatory particle, lid subcomplex
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0016579--P:protein deubiquitination
GO:0046677--P:response to antibiotic
GO:0046898--P:response to cycloheximide

KEGG

spo:SPAC31G5.13

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000544	Aegilops tauschii	71.52	2.00e-122	429.00
IUUC-Aml-001416	Ailuropoda melanoleuca	70.59	2.00e-124	436.00
IUUC-Atr-002629	Amborella trichopoda	70.45	1.00e-115	407.00
IUUC-Apl-004046	Anas platyrhynchos	69.59	3.00e-124	435.00
IUUC-Aca-005228	Anolis carolinensis	70.59	4.00e-124	435.00
IUUC-Aly-005457	Arabidopsis lyrata	70.87	1.00e-118	417.00
IUUC-Ath-007290	Arabidopsis thaliana	70.87	5.00e-119	418.00
IUUC-Ago-007866	Ashbya gossypii	63.14	3.00e-113	399.00
IUUC-Acl-008338	Aspergillus clavatus	70.54	4.00e-110	388.00
IUUC-Afl-008431	Aspergillus flavus	73.01	8.00e-126	441.00
IUUC-Afu-008909	Aspergillus fumigatus	71.97	9.00e-120	421.00
IUUC-Ani-009174	Aspergillus nidulans	68.69	5.00e-126	441.00
IUUC-Ang-009854	Aspergillus niger	70.65	4.00e-128	448.00
IUUC-Aor-009942	Aspergillus oryzae	73.01	2.00e-125	439.00
IUUC-Ate-010377	Aspergillus terreus	69.23	4.00e-126	442.00
IUUC-Ame-011628	Astyanax mexicanus	72.80	8.00e-115	404.00
IUUC-Bgr-012263	Blumeria graminis	67.73	5.00e-114	401.00
IUUC-Bta-012375	Bos taurus	70.59	2.00e-124	436.00
IUUC-Bci-013850	Botrytis cinerea	73.70	4.00e-117	412.00
IUUC-Bdi-014488	Brachypodium distachyon	71.10	1.00e-117	413.00
IUUC-Bol-016172	Brassica oleracea	70.87	5.00e-119	418.00
IUUC-Bra-017926	Brassica rapa	70.87	5.00e-119	418.00
IUUC-Cel-018247	Caenorhabditis elegans	65.74	7.00e-115	404.00
IUUC-Cja-019210	Callithrix jacchus	69.83	3.00e-124	436.00
IUUC-Cfa-020926	Canis familiaris	69.55	1.00e-120	423.00
IUUC-Cpo-021572	Cavia porcellus	70.59	2.00e-124	436.00
IUUC-Cre-022925	Chlamydomonas reinhardtii	70.93	1.00e-115	406.00
IUUC-Csa-023496	Chlorocebus sabaeus	70.59	2.00e-124	436.00
IUUC-Cho-024525	Choloepus hoffmanni	65.88	6.00e-116	407.00
IUUC-Cin-025492	Ciona intestinalis	70.00	6.00e-125	437.00
IUUC-Cgl-026493	Colletotrichum gloeosporioides	72.28	3.00e-108	382.00
IUUC-Cne-026785	Cryptococcus neoformans	67.63	1.00e-115	407.00
IUUC-Cme-027105	Cyanidioschyzon merolae	56.44	8.00e-96	341.00
IUUC-Dre-028788	Danio rerio	70.59	1.00e-123	433.00
IUUC-Dno-029058	Dasypus novemcinctus	69.13	1.00e-124	437.00
IUUC-Dor-031015	Dipodomys ordii	63.32	2.00e-105	373.00
IUUC-Dse-031242	Dothistroma septosporum	73.26	1.00e-128	450.00
IUUC-Dme-031668	Drosophila melanogaster	67.86	3.00e-125	439.00
IUUC-Ete-033146	Echinops telfairi	64.15	9.00e-100	353.00
IUUC-Eca-033734	Equus caballus	70.59	2.00e-124	436.00
IUUC-Eeu-035168	Erinaceus europaeus	86.67	9.00e-78	281.00
IUUC-Fca-036426	Felis catus	70.59	2.00e-124	436.00
IUUC-Fal-036954	Ficedula albicollis	70.59	4.00e-124	435.00
IUUC-Fox-037838	Fusarium oxysporum	72.63	2.00e-124	436.00
IUUC-Fso-038374	Fusarium solani	72.63	1.00e-124	437.00
IUUC-Gmo-038918	Gadus morhua	70.59	2.00e-123	433.00
IUUC-Ggr-039954	Gaeumannomyces graminis	69.26	1.00e-128	450.00
IUUC-Gga-040377	Gallus gallus	70.59	4.00e-124	435.00
IUUC-Gac-042386	Gasterosteus aculeatus	67.95	5.00e-125	438.00
IUUC-Gma-042811	Glycine max	70.87	4.00e-118	415.00
IUUC-Ggo-044916	Gorilla gorilla	69.13	1.00e-124	437.00
IUUC-Hsa-045865	Homo sapiens	70.59	2.00e-124	436.00
IUUC-Hvu-047188	Hordeum vulgare	71.20	4.00e-122	429.00
IUUC-Itr-048154	Ictidomys tridecemlineatus	82.12	6.00e-87	310.00
IUUC-Kpa-049128	Komagataella pastoris	72.73	2.00e-114	403.00
IUUC-Lch-050167	Latimeria chalumnae	64.60	8.00e-111	390.00
IUUC-Lpe-051086	Leersia perrieri	70.45	1.00e-120	424.00
IUUC-Loc-052888	Lepisosteus oculatus	70.59	5.00e-124	434.00
IUUC-Lma-052962	Leptosphaeria maculans	71.06	1.00e-128	450.00
IUUC-Laf-053949	Loxodonta africana	70.59	2.00e-124	436.00
IUUC-Mcc-055279	Macaca mulatta	71.38	2.00e-120	423.00
IUUC-Meu-055956	Macropus eugenii	64.36	6.00e-109	384.00
IUUC-Mor-057166	Magnaporthe oryzae	70.29	6.00e-120	421.00
IUUC-Mpo-057344	Magnaporthe poae	69.26	4.00e-128	448.00
IUUC-Mtr-057857	Medicago truncatula	70.55	4.00e-118	415.00
IUUC-Mla-058938	Melampsora laricipopulina	70.53	4.00e-129	451.00
IUUC-Mga-060093	Meleagris gallopavo	70.59	4.00e-124	435.00
IUUC-Mvi-060565	Microbotryum violaceum	70.77	2.00e-123	433.00
IUUC-Mmr-060899	Microcebus murinus	71.38	1.00e-120	423.00
IUUC-Mdo-062175	Monodelphis domestica	70.59	3.00e-124	435.00
IUUC-Mmu-063416	Mus musculus	70.59	2.00e-124	436.00
IUUC-Mac-064901	Musa acuminata	69.23	6.00e-118	414.00
IUUC-Mpu-065946	Mustela putorius furo	70.59	2.00e-124	436.00
IUUC-Mlu-067835	Myotis lucifugus	68.90	5.00e-124	435.00
IUUC-Nfi-068279	Neosartorya fischeri	71.97	1.00e-119	420.00
IUUC-Ncr-068821	Neurospora crassa	73.33	4.00e-117	412.00
IUUC-Nle-069212	Nomascus leucogenys	70.59	2.00e-124	436.00
IUUC-Opr-070928	Ochotona princeps	46.84	9.00e-56	207.00
IUUC-Ont-072135	Oreochromis niloticus	70.59	5.00e-124	434.00
IUUC-Oan-072755	Ornithorhynchus anatinus	70.59	3.00e-124	435.00
IUUC-Ocu-074433	Oryctolagus cuniculus	73.48	8.00e-119	417.00
IUUC-Oba-075351	Oryza barthii	70.45	1.00e-116	410.00
IUUC-Obr-076756	Oryza brachyantha	70.45	1.00e-120	424.00
IUUC-Ogl-077831	Oryza glaberrima	70.45	1.00e-116	410.00
IUUC-Ogu-078028	Oryza glumaepatula	70.45	1.00e-116	410.00
IUUC-Oin-080184	Oryza indica	70.45	9.00e-121	424.00
IUUC-Olo-080580	Oryza longistaminata	72.95	2.00e-115	406.00
IUUC-Ome-081739	Oryza meridionalis	68.45	3.00e-114	402.00
IUUC-Oni-082861	Oryza nivara	70.45	1.00e-116	410.00
IUUC-Opu-083352	Oryza punctata	70.45	1.00e-116	410.00
IUUC-Oru-084210	Oryza rufipogon	70.45	1.00e-116	410.00
IUUC-Osa-086114	Oryza sativa	70.45	1.00e-116	410.00
IUUC-Ola-087317	Oryzias latipes	70.59	5.00e-124	434.00
IUUC-Olu-087889	Ostreococcus lucimarinus	66.12	4.00e-119	418.00
IUUC-Oga-088032	Otolemur garnettii	69.59	9.00e-125	437.00
IUUC-Oar-090237	Ovis aries	70.59	3.00e-124	435.00
IUUC-Ptr-090881	Pan troglodytes	70.59	2.00e-124	436.00
IUUC-Pan-092658	Papio anubis	69.46	4.00e-125	438.00
IUUC-Psi-093672	Pelodiscus sinensis	70.59	3.00e-124	435.00
IUUC-Pma-094213	Petromyzon marinus	70.93	5.00e-124	434.00
IUUC-Pno-095038	Phaeosphaeria nodorum	71.38	3.00e-129	452.00
IUUC-Ppa-095637	Physcomitrella patens	73.01	7.00e-118	414.00
IUUC-Pfo-096322	Poecilia formosa	70.59	5.00e-124	434.00
IUUC-Pab-098484	Pongo abelii	70.59	2.00e-124	436.00
IUUC-Pop-099564	Populus trichocarpa	70.55	2.00e-117	413.00
IUUC-Pca-100785	Procavia capensis	66.42	3.00e-103	365.00
IUUC-Ppe-101727	Prunus persica	72.66	2.00e-117	413.00
IUUC-Pva-102569	Pteropus vampyrus	70.59	5.00e-124	434.00
IUUC-Pgr-103351	Puccinia graminis	70.20	2.00e-129	452.00
IUUC-Ptt-103763	Puccinia triticina	67.33	2.00e-119	420.00
IUUC-Pte-104088	Pyrenophora teres	70.42	2.00e-128	449.00
IUUC-Pyt-104597	Pyrenophora triticirepentis	73.13	2.00e-118	416.00
IUUC-Rno-105115	Rattus norvegicus	70.59	2.00e-124	436.00
IUUC-Sce-106353	Saccharomyces cerevisiae	64.29	4.00e-114	402.00
IUUC-Sha-107476	Sarcophilus harrisii	70.59	3.00e-124	435.00
IUUC-Sja-107807	Schizosaccharomyces japonicus	88.96	1.00e-167	579.00
IUUC-Ssl-108392	Sclerotinia sclerotiorum	74.39	5.00e-118	415.00
IUUC-Smo-108824	Selaginella moellendorffii	71.79	1.00e-129	453.00
IUUC-Sit-110287	Setaria italica	70.45	1.00e-120	424.00
IUUC-Sly-111656	Solanum lycopersicum	69.90	4.00e-117	412.00
IUUC-Stu-112827	Solanum tuberosum	70.23	1.00e-117	413.00
IUUC-Sar-112979	Sorex araneus	62.50	4.00e-105	372.00
IUUC-Sbi-113841	Sorghum bicolor	70.45	1.00e-120	424.00
IUUC-Sre-114930	Sporisorium reilianum	73.48	3.00e-126	442.00
IUUC-Ssc-116058	Sus scrofa	69.36	2.00e-124	436.00
IUUC-Tgu-116499	Taeniopygia guttata	70.59	4.00e-124	435.00
IUUC-Tru-117576	Takifugu rubripes	70.59	5.00e-124	434.00
IUUC-Tsy-119371	Tarsius syrichta	61.82	2.00e-105	373.00
IUUC-Tni-120868	Tetraodon nigroviridis	70.24	5.00e-122	428.00
IUUC-Tca-121292	Theobroma cacao	70.23	4.00e-117	412.00
IUUC-Tre-122183	Trichoderma reesei	73.68	2.00e-122	429.00
IUUC-Tvi-122566	Trichoderma virens	73.68	2.00e-122	430.00
IUUC-Tae-125156	Triticum aestivum	71.52	4.00e-122	428.00
IUUC-Tur-126034	Triticum urartu	74.02	3.00e-117	412.00
IUUC-Tme-126903	Tuber melanosporum	69.13	5.00e-128	448.00
IUUC-Tbe-127525	Tupaia belangeri	62.45	7.00e-100	354.00
IUUC-Ttr-129072	Tursiops truncatus	70.59	4.00e-124	435.00
IUUC-Uma-129471	Ustilago maydis	70.16	1.00e-126	444.00
IUUC-Vda-129956	Verticillium dahliae	74.04	3.00e-116	409.00
IUUC-Vpa-130490	Vicugna pacos	70.59	4.00e-124	435.00
IUUC-Vvi-131302	Vitis vinifera	70.55	1.00e-117	413.00
IUUC-Xtr-132059	Xenopus tropicalis	70.93	1.00e-124	437.00
IUUC-Xma-133101	Xiphophorus maculatus	70.59	5.00e-124	434.00
IUUC-Yli-134638	Yarrowia lipolytica	66.77	3.00e-120	422.00
IUUC-Zma-135910	Zea mays	70.45	1.00e-120	424.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence