iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Gac-041471

UUCD1 version

UUC-GaA-00781

Ensembl Protein ID

ENSGACP00000020047.1

UniProt Accession

G3PR12; G3PR12_GASAC

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGACG00000015200.1	ENSGACT00000020086.1	ENSGACP00000020047.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.10e-34	117.3	278	313
E3 activity/RING/U-box	4.00e-24	84.9	401	470
UBD/Beta-Prp	8.20e-56	189.8	5	221

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           H+  vt+++f ++ +l+++Gs D+t+ +W+l +g  
   Q: 278  HKRYVTACCFsPTsPLIATGSMDKTVNIWRLEDGCT 313
           999********777*****************99976 PP

E3 activity/RING/U-box

   S: 2    vpeeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqawcee 71
           +p+eflCpI+ elMr+Pv++++G++y+r++I  w+ ++++++P+t+ pl  + l+Pn+tl+  i +w   
   Q: 401  IPDEFLCPITRELMREPVIAADGYSYEREAIDSWIGTKNRSSPMTNLPLMTTLLTPNHTLKMAIGRWKTN 470
           8******************************************************************865 PP

UBD/Beta-Prp

   S: 2    iktlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkl..lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvh 88
           i+tl++h+++v    +f  +++l+at s d+t+++++ ++ +   ++ lsgh  +v +++fs  g++l+++s+D+t  vw+  tg++  
   Q: 5    ICTLQDHRDDVNW-CAF--SGKLFATCSGDKTLRIYSSRDFSElpFSPLSGHGYGVHCCCFSTCGQFLASCSTDATTMVWSTATGEIEA 90
           89*******9887.688..9********************777899******************************************* PP
   S: 89   tlk.ghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtlt 176
           +l+    + v+ +++sp++ +lvsG +d t+ +wd ++++  + t +++d +    +++p ++++vsGs+ + +rlWdl +++l  +  
   Q: 91   VLEhPGRSPVRICALSPDSAHLVSGASDGTLALWDFPSKKLRR-TGAVNDTTMVACSFSPCSQVFVSGSTYGDMRLWDLDMNQLHAEKN 178
           **9334678*******************************999.******999999****99**********************99998 PP
   S: 177  gghtdsvyslsfdsng........kelvsgsldgtvklwdlqtg 212
             h+  v++ +f ++         ++l+s+++d+ +k+w + ++
   Q: 179  A-HDLGVTCCTFAPSIlsgsqvvqFRLASCGQDSLLKIWAVDNS 221
           7.*********9997788899999***************98765 PP

Organism

Gasterosteus aculeatus

Protein Sequence
(Fasta)

MTSLICTLQD HRDDVNWCAF SGKLFATCSG DKTLRIYSSR DFSELPFSPL SGHGYGVHCC 60
CFSTCGQFLA SCSTDATTMV WSTATGEIEA VLEHPGRSPV RICALSPDSA HLVSGASDGT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGTTGGAGGA GGAAGTAAAC AACGCCGAAT TGAAGGGACA AAACGTCAGG AGAAAGGTAA 60
AGTACGCTGC CGCGGTCAGA CGTAACGTCA GCTTACGTTT CAGTCAGATT CATTAACCGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001660--SAM
IPR013761--SAM/pointed
IPR003613--Ubox_domain
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50105--SAM_DOMAIN
PS51698--U_BOX
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00536--SAM_1
PF04564--U-box
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00454--SAM
SM00504--Ubox
SM00320--WD40

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001614	Ailuropoda melanoleuca	57.98	1.00e-157	549.00
IUUC-Apl-003529	Anas platyrhynchos	58.44	2.00e-155	542.00
IUUC-Aca-004257	Anolis carolinensis	55.65	5.00e-153	534.00
IUUC-Ame-011357	Astyanax mexicanus	61.89	1.00e-150	526.00
IUUC-Bta-013032	Bos taurus	56.78	3.00e-154	538.00
IUUC-Cja-018743	Callithrix jacchus	57.98	2.00e-156	545.00
IUUC-Cfa-021197	Canis familiaris	58.40	5.00e-158	550.00
IUUC-Cpo-022279	Cavia porcellus	57.35	2.00e-155	542.00
IUUC-Csa-023954	Chlorocebus sabaeus	58.19	2.00e-157	548.00
IUUC-Cho-025083	Choloepus hoffmanni	44.39	7.00e-84	303.00
IUUC-Cin-025786	Ciona intestinalis	35.83	1.00e-85	310.00
IUUC-Dre-028087	Danio rerio	71.72	0.00e+00	670.00
IUUC-Dno-028919	Dasypus novemcinctus	58.19	2.00e-157	548.00
IUUC-Dor-031112	Dipodomys ordii	58.19	2.00e-157	549.00
IUUC-Ete-032405	Echinops telfairi	55.56	3.00e-105	375.00
IUUC-Eca-033254	Equus caballus	57.05	8.00e-157	546.00
IUUC-Eeu-034545	Erinaceus europaeus	57.14	8.00e-151	526.00
IUUC-Fca-035482	Felis catus	58.19	3.00e-157	548.00
IUUC-Fal-036976	Ficedula albicollis	46.96	2.00e-110	392.00
IUUC-Gmo-039213	Gadus morhua	75.00	0.00e+00	691.00
IUUC-Gga-040561	Gallus gallus	56.03	6.00e-149	520.00
IUUC-Ggo-045503	Gorilla gorilla	57.77	9.00e-157	546.00
IUUC-Hsa-045910	Homo sapiens	57.77	1.00e-156	546.00
IUUC-Itr-048214	Ictidomys tridecemlineatus	55.56	1.00e-115	409.00
IUUC-Loc-052307	Lepisosteus oculatus	66.47	0.00e+00	678.00
IUUC-Laf-053587	Loxodonta africana	58.82	7.00e-159	553.00
IUUC-Mcc-055679	Macaca mulatta	57.98	1.00e-156	546.00
IUUC-Meu-055962	Macropus eugenii	50.00	2.00e-122	432.00
IUUC-Mga-059652	Meleagris gallopavo	56.24	9.00e-151	526.00
IUUC-Mmr-060943	Microcebus murinus	57.32	4.00e-150	524.00
IUUC-Mdo-062592	Monodelphis domestica	57.59	6.00e-155	540.00
IUUC-Mmu-063577	Mus musculus	58.28	1.00e-156	546.00
IUUC-Mpu-066422	Mustela putorius furo	58.19	4.00e-157	547.00
IUUC-Mlu-067250	Myotis lucifugus	57.35	4.00e-154	537.00
IUUC-Nle-069517	Nomascus leucogenys	57.77	5.00e-157	547.00
IUUC-Opr-070776	Ochotona princeps	58.81	3.00e-159	554.00
IUUC-Ont-071821	Oreochromis niloticus	85.05	0.00e+00	805.00
IUUC-Oan-073706	Ornithorhynchus anatinus	57.42	5.00e-155	540.00
IUUC-Ocu-074766	Oryctolagus cuniculus	53.35	6.00e-140	490.00
IUUC-Ola-086531	Oryzias latipes	83.90	0.00e+00	776.00
IUUC-Oga-088388	Otolemur garnettii	58.19	5.00e-158	550.00
IUUC-Oar-089748	Ovis aries	57.42	6.00e-155	540.00
IUUC-Ptr-090616	Pan troglodytes	57.51	6.00e-155	540.00
IUUC-Pan-091769	Papio anubis	56.85	4.00e-106	377.00
IUUC-Psi-093334	Pelodiscus sinensis	57.77	2.00e-142	499.00
IUUC-Pma-094383	Petromyzon marinus	44.47	9.00e-119	420.00
IUUC-Pfo-096801	Poecilia formosa	78.33	0.00e+00	731.00
IUUC-Pab-098139	Pongo abelii	56.07	2.00e-122	431.00
IUUC-Pca-100523	Procavia capensis	54.49	2.00e-94	339.00
IUUC-Pva-102286	Pteropus vampyrus	58.05	1.00e-150	526.00
IUUC-Rno-104831	Rattus norvegicus	57.11	1.00e-154	539.00
IUUC-Sha-107499	Sarcophilus harrisii	57.98	7.00e-157	546.00
IUUC-Sar-113389	Sorex araneus	56.93	1.00e-151	529.00
IUUC-Tgu-116769	Taeniopygia guttata	55.53	5.00e-151	527.00
IUUC-Tru-118774	Takifugu rubripes	81.03	0.00e+00	748.00
IUUC-Tsy-119595	Tarsius syrichta	49.02	5.00e-101	360.00
IUUC-Tni-119850	Tetraodon nigroviridis	82.38	0.00e+00	773.00
IUUC-Tbe-127938	Tupaia belangeri	50.65	3.00e-83	301.00
IUUC-Ttr-128193	Tursiops truncatus	56.91	4.00e-126	444.00
IUUC-Vpa-130275	Vicugna pacos	57.56	8.00e-157	546.00
IUUC-Xtr-131982	Xenopus tropicalis	51.06	4.00e-131	461.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence