iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
RAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
CPLM	dbPAF
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	7.10e-10	39.5	34	112

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmelees..............ksklmveikdvqpevfrallkFlYtgkld 66
           +D ++  +g e+++h++vLaa+S++F++lf+ +   +                 +  e++ v pe++ all+F Yt +l+
   Q: 34   CDLTIRTQGLEYRTHRAVLAACSHYFKKLFTEGGGGTvmgtggggtaaggaG-AGVCELDFVGPEALGALLEFAYTATLT 112
           89****************************77776557899*******9954.88888888***************9986 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MGSPEDDLIG IPFPDHSSEL LSCLNEQRQL GHLCDLTIRT QGLEYRTHRA VLAACSHYFK 60
KLFTEGGGGT VMGTGGGGTA AGGAGAGVCE LDFVGPEALG ALLEFAYTAT LTTSSANMPA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGAGTGGGAG CCAGGTGAAT GTACGGCTCT CCGCGGCCAA GGGGGGGCGG GCAGCAGGAG 60
GAGGCAAAGG GTGGCGGAGG AGGAGCCCCC CAGCAACGAG CAGCGAGCCA CTGACCGCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000210--BTB/POZ_dom
IPR023413--GFP-like
IPR011333--SKP1/BTB/POZ
IPR013087--Znf_C2H2_type

PROSITE

PS50097--BTB
PS00028--ZINC_FINGER_C2H2_1
PS50157--ZINC_FINGER_C2H2_2

Pfam

PF00651--BTB

SMART

SM00225--BTB
SM00355--ZnF_C2H2

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0046872--F:metal ion binding
GO:0000978--F:RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077--F:transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0010628--P:positive regulation of gene expression
GO:0043370--P:regulation of CD4-positive, alpha-beta T cell differentiation
GO:0043376--P:regulation of CD8-positive, alpha-beta T cell differentiation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aca-005247	Anolis carolinensis	55.75	9.00e-50	190.00
IUUC-Ame-010706	Astyanax mexicanus	85.25	1.00e-61	229.00
IUUC-Bta-013174	Bos taurus	89.32	0.00e+00	756.00
IUUC-Cja-019527	Callithrix jacchus	91.34	0.00e+00	735.00
IUUC-Cfa-021183	Canis familiaris	91.36	0.00e+00	809.00
IUUC-Cpo-021564	Cavia porcellus	92.86	0.00e+00	754.00
IUUC-Csa-024245	Chlorocebus sabaeus	91.71	0.00e+00	735.00
IUUC-Dre-028292	Danio rerio	84.17	9.00e-61	227.00
IUUC-Dno-028864	Dasypus novemcinctus	89.32	0.00e+00	710.00
IUUC-Dor-031131	Dipodomys ordii	89.89	0.00e+00	753.00
IUUC-Eca-033561	Equus caballus	80.85	0.00e+00	665.00
IUUC-Eeu-035040	Erinaceus europaeus	75.34	5.00e-97	347.00
IUUC-Fal-036849	Ficedula albicollis	80.98	8.00e-92	330.00
IUUC-Gmo-038776	Gadus morhua	81.30	1.00e-58	220.00
IUUC-Gga-040853	Gallus gallus	89.73	3.00e-77	282.00
IUUC-Gac-041877	Gasterosteus aculeatus	83.46	1.00e-63	236.00
IUUC-Ggo-044434	Gorilla gorilla	91.53	0.00e+00	728.00
IUUC-Hsa-046812	Homo sapiens	91.34	0.00e+00	726.00
IUUC-Itr-048180	Ictidomys tridecemlineatus	91.71	0.00e+00	781.00
IUUC-Lch-049665	Latimeria chalumnae	52.61	2.00e-120	426.00
IUUC-Mcc-055723	Macaca mulatta	91.53	0.00e+00	721.00
IUUC-Meu-056152	Macropus eugenii	77.06	8.00e-140	489.00
IUUC-Mmr-061549	Microcebus murinus	91.76	0.00e+00	795.00
IUUC-Mdo-061946	Monodelphis domestica	79.92	0.00e+00	696.00
IUUC-Mmu-064201	Mus musculus	97.45	0.00e+00	793.00
IUUC-Mpu-066752	Mustela putorius furo	85.29	0.00e+00	767.00
IUUC-Nle-069749	Nomascus leucogenys	91.71	0.00e+00	734.00
IUUC-Ocu-074243	Oryctolagus cuniculus	90.42	2.00e-123	435.00
IUUC-Ola-087497	Oryzias latipes	70.30	2.00e-64	239.00
IUUC-Oga-088753	Otolemur garnettii	87.36	0.00e+00	758.00
IUUC-Ptr-091391	Pan troglodytes	91.34	0.00e+00	726.00
IUUC-Pan-092553	Papio anubis	91.34	0.00e+00	730.00
IUUC-Pfo-096585	Poecilia formosa	82.68	3.00e-63	236.00
IUUC-Pab-097962	Pongo abelii	91.71	0.00e+00	731.00
IUUC-Pva-102850	Pteropus vampyrus	85.66	0.00e+00	640.00
IUUC-Sha-107232	Sarcophilus harrisii	79.60	0.00e+00	702.00
IUUC-Ssc-116341	Sus scrofa	86.55	2.00e-89	322.00
IUUC-Tni-120444	Tetraodon nigroviridis	81.34	5.00e-64	238.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence