iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

mRNA Expression
GEO	FFGED
Protein-protein Interaction
IID	iRefIndex	HINT	Mentha
Post-translational Modifications (PTMs)
CPLM	dbPAF	dbPTM	UniProt
BioGRID
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	4.20e-17	60.3	55	109

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           +e+v++lyd+eaq+d++L+lk Gd+++v+  e+ + +W +g  + ++k G+fP+n+v+ 
   Q: 55   EEYVEALYDFEAQQDGDLSLKTGDKIQVL--EKISPDWYRG--KSNNKIGIFPANYVKP 109
           689**************************..99********..89************96 PP

Organism

Saccharomyces cerevisiae

Functional Description
(View)

Involved in resistance to EDTA.

Protein Sequence
(Fasta)

MSASLVNRSL KNIRNELEFL KESNVISGDI FELINSKLPE KWDGNQRSPQ NADTEEYVEA 60
LYDFEAQQDG DLSLKTGDKI QVLEKISPDW YRGKSNNKIG IFPANYVKPA FTRSASPKSA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCTGCGT CACTAGTGAA TCGATCATTG AAAAATATAA GGAATGAATT AGAATTTTTG 60
AAGGAATCAA ACGTCATATC AGGCGACATT TTCGAATTAA TCAATAGCAA GTTACCTGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0007--Acetylation
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-1017--Isopeptide bond
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0832--Ubl conjugation

Interpro

IPR001452--SH3_domain

PROSITE

PS50002--SH3

Pfam

PF00018--SH3_1

PRINTS

PR00452--SH3DOMAIN

SMART

SM00326--SH3

Gene Ontology

GO:0030479--C:actin cortical patch
GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0032587--C:ruffle membrane
GO:0051015--F:actin filament binding
GO:0035091--F:phosphatidylinositol binding
GO:0051666--P:actin cortical patch localization
GO:0051017--P:actin filament bundle assembly
GO:0034316--P:negative regulation of Arp2/3 complex-mediated actin nucleation
GO:1900027--P:regulation of ruffle assembly

KEGG

sce:YGR136W

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001150	Aegilops tauschii	23.08	6.80e-01	26.20
IUUC-Aml-001834	Ailuropoda melanoleuca	57.69	2.00e-14	72.80
IUUC-Apl-003344	Anas platyrhynchos	46.03	1.00e-13	70.10
IUUC-Bta-012502	Bos taurus	45.95	5.00e-14	70.90
IUUC-Cja-019613	Callithrix jacchus	45.00	1.00e-13	67.00
IUUC-Cfa-020664	Canis familiaris	53.85	3.00e-13	68.60
IUUC-Cpo-022534	Cavia porcellus	48.33	3.00e-13	67.00
IUUC-Csa-024210	Chlorocebus sabaeus	40.74	3.00e-14	72.40
IUUC-Cho-024868	Choloepus hoffmanni	36.78	6.00e-14	70.90
IUUC-Dor-030493	Dipodomys ordii	45.00	7.00e-13	65.90
IUUC-Eca-033653	Equus caballus	38.30	1.00e-13	69.70
IUUC-Fca-036080	Felis catus	55.77	3.00e-13	68.90
IUUC-Fal-037649	Ficedula albicollis	51.72	1.00e-13	69.70
IUUC-Gga-040572	Gallus gallus	50.77	5.00e-14	70.90
IUUC-Ggo-044910	Gorilla gorilla	40.74	1.00e-14	73.20
IUUC-Hsa-046590	Homo sapiens	40.74	5.00e-14	71.20
IUUC-Itr-047880	Ictidomys tridecemlineatus	37.00	6.00e-14	70.90
IUUC-Laf-053588	Loxodonta africana	41.98	3.00e-15	75.10
IUUC-Mcc-055832	Macaca mulatta	40.74	3.00e-14	72.40
IUUC-Mga-059651	Meleagris gallopavo	46.38	6.00e-14	70.90
IUUC-Mmr-061755	Microcebus murinus	45.00	7.00e-13	65.90
IUUC-Mdo-061881	Monodelphis domestica	50.00	4.00e-14	72.00
IUUC-Mmu-063550	Mus musculus	49.23	1.00e-13	69.70
IUUC-Mpu-066280	Mustela putorius furo	53.85	5.00e-14	70.90
IUUC-Mlu-067585	Myotis lucifugus	58.33	1.00e-13	69.70
IUUC-Nle-069589	Nomascus leucogenys	40.74	2.00e-14	72.40
IUUC-Oan-073575	Ornithorhynchus anatinus	59.18	1.00e-13	68.90
IUUC-Ocu-074487	Oryctolagus cuniculus	37.37	7.00e-15	74.30
IUUC-Oba-075752	Oryza barthii	32.73	2.90e-02	33.50
IUUC-Oga-088091	Otolemur garnettii	53.85	3.00e-13	68.20
IUUC-Oar-090100	Ovis aries	45.95	5.00e-14	71.20
IUUC-Ptr-090777	Pan troglodytes	40.74	3.00e-14	72.00
IUUC-Pan-092179	Papio anubis	40.74	2.00e-14	72.40
IUUC-Pab-098395	Pongo abelii	40.74	2.00e-14	71.60
IUUC-Pca-100838	Procavia capensis	45.00	2.00e-13	68.20
IUUC-Pgr-103578	Puccinia graminis	53.57	2.00e-12	63.90
IUUC-Sha-107633	Sarcophilus harrisii	55.77	1.00e-13	70.50
IUUC-Ssc-116331	Sus scrofa	40.74	1.00e-13	69.70
IUUC-Tgu-117385	Taeniopygia guttata	51.72	2.00e-13	68.90
IUUC-Tsy-119158	Tarsius syrichta	50.77	8.00e-14	70.10
IUUC-Ttr-128961	Tursiops truncatus	38.16	5.00e-13	66.20
IUUC-Vpa-130409	Vicugna pacos	40.24	2.00e-15	75.50

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence