iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Dre-027693

Ensembl Protein ID

ENSDARP00000068125.3

UniProt Accession

F1QZ06; F1QZ06_DANRE

Genbank Protein ID

ENSDARP00000068125

Protein Name

Neutral sphingomyelinase (N-SMase) activation-associated factor

Genbank Nucleotide ID

CR354563

Gene Name

nsmaf

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000051920.4	ENSDART00000073635.4	ENSDARP00000068125.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.20e-24	86.3	705	734

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclafsdtllvsGsdDgtikvWDl 30
           gH d v+++++ d+ l ++s+D t+kvW+ 
   Q: 705  GHDDAVSDICWRDDKLYTASWDSTVKVWEC 734
           8**********77999************96 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MAFITKKDRS KERFSLLLLD LEEQYFEQHI AYNLTNRGPE TNRRTNGSLK ICSKSVIFEP 60
DDAVKPILKI PLKDCSEIAA VEETAHNPFI ESKPACIVIK TKQIYQIKEE NVVAPYKYDR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTATTTCCGT GTTTACATGT CTGTCTGCTG CAGCAGCTGA GCCCTCATGG CTTTCATCAC 60
GAAGAAGGAT CGCAGCAAAG AACGGTATAG TACTTACACA TTTCTTTTGC GTTGCGGTAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR000409--BEACH_dom
IPR004182--GRAM
IPR023362--PH-BEACH_dom
IPR011993--PH_dom-like
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50197--BEACH
PS51783--PH_BEACH
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF02138--Beach
PF02893--GRAM
PF00400--WD40

SMART

SM01026--Beach
SM00568--GRAM
SM00320--WD40

Gene Ontology

GO:0002233--P:leukocyte chemotaxis involved in immune response
GO:0002232--P:leukocyte chemotaxis involved in inflammatory response
GO:0030593--P:neutrophil chemotaxis

KEGG

dre:550506

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001408	Ailuropoda melanoleuca	69.69	0.00e+00	1308.00
IUUC-Apl-004000	Anas platyrhynchos	69.10	0.00e+00	1289.00
IUUC-Aca-005253	Anolis carolinensis	68.36	0.00e+00	1254.00
IUUC-Ame-011654	Astyanax mexicanus	81.66	0.00e+00	1462.00
IUUC-Bta-013201	Bos taurus	68.99	0.00e+00	1288.00
IUUC-Cja-019039	Callithrix jacchus	70.11	0.00e+00	1298.00
IUUC-Cfa-020722	Canis familiaris	69.84	0.00e+00	1307.00
IUUC-Cpo-022247	Cavia porcellus	70.28	0.00e+00	1282.00
IUUC-Csa-023753	Chlorocebus sabaeus	70.73	0.00e+00	1314.00
IUUC-Cho-024757	Choloepus hoffmanni	73.16	0.00e+00	1110.00
IUUC-Dno-028878	Dasypus novemcinctus	70.55	0.00e+00	1284.00
IUUC-Dor-030632	Dipodomys ordii	60.26	0.00e+00	1077.00
IUUC-Ete-032305	Echinops telfairi	63.05	0.00e+00	738.00
IUUC-Eca-034177	Equus caballus	70.40	0.00e+00	1304.00
IUUC-Eeu-034512	Erinaceus europaeus	62.83	1.00e-147	517.00
IUUC-Fca-036028	Felis catus	69.58	0.00e+00	1301.00
IUUC-Fal-036685	Ficedula albicollis	68.92	0.00e+00	1246.00
IUUC-Gmo-038959	Gadus morhua	73.23	0.00e+00	1201.00
IUUC-Gga-040819	Gallus gallus	68.63	0.00e+00	1274.00
IUUC-Gac-041843	Gasterosteus aculeatus	71.94	0.00e+00	1342.00
IUUC-Ggo-045488	Gorilla gorilla	64.94	0.00e+00	1185.00
IUUC-Hsa-046714	Homo sapiens	70.67	0.00e+00	1313.00
IUUC-Itr-048950	Ictidomys tridecemlineatus	74.01	0.00e+00	1118.00
IUUC-Lch-050024	Latimeria chalumnae	59.44	0.00e+00	1041.00
IUUC-Loc-052831	Lepisosteus oculatus	75.19	0.00e+00	1399.00
IUUC-Laf-053693	Loxodonta africana	69.40	0.00e+00	1281.00
IUUC-Mcc-054769	Macaca mulatta	69.58	0.00e+00	1285.00
IUUC-Mga-059891	Meleagris gallopavo	69.37	0.00e+00	1259.00
IUUC-Mmr-060948	Microcebus murinus	70.47	0.00e+00	1302.00
IUUC-Mdo-062721	Monodelphis domestica	67.57	0.00e+00	1286.00
IUUC-Mmu-064167	Mus musculus	70.36	0.00e+00	1318.00
IUUC-Mpu-066243	Mustela putorius furo	69.60	0.00e+00	1314.00
IUUC-Mlu-068009	Myotis lucifugus	70.01	0.00e+00	1263.00
IUUC-Nle-069459	Nomascus leucogenys	70.44	0.00e+00	1309.00
IUUC-Opr-071145	Ochotona princeps	64.91	0.00e+00	1066.00
IUUC-Ont-071781	Oreochromis niloticus	70.79	0.00e+00	1340.00
IUUC-Oan-073456	Ornithorhynchus anatinus	69.36	0.00e+00	1281.00
IUUC-Ocu-073989	Oryctolagus cuniculus	69.16	0.00e+00	1312.00
IUUC-Ola-087535	Oryzias latipes	68.72	0.00e+00	1283.00
IUUC-Oga-089183	Otolemur garnettii	67.67	0.00e+00	1221.00
IUUC-Oar-090420	Ovis aries	69.14	0.00e+00	1258.00
IUUC-Ptr-091559	Pan troglodytes	70.22	0.00e+00	1328.00
IUUC-Pan-092213	Papio anubis	70.80	0.00e+00	1316.00
IUUC-Psi-093142	Pelodiscus sinensis	69.72	0.00e+00	1282.00
IUUC-Ppa-095631	Physcomitrella patens	39.57	1.00e-121	431.00
IUUC-Pfo-096451	Poecilia formosa	71.23	0.00e+00	1325.00
IUUC-Pab-098016	Pongo abelii	68.88	0.00e+00	1297.00
IUUC-Pca-100416	Procavia capensis	62.00	0.00e+00	1108.00
IUUC-Pva-102630	Pteropus vampyrus	68.00	0.00e+00	1252.00
IUUC-Rno-105516	Rattus norvegicus	70.03	0.00e+00	1315.00
IUUC-Sha-107116	Sarcophilus harrisii	67.57	0.00e+00	1287.00
IUUC-Smo-108747	Selaginella moellendorffii	40.40	2.00e-115	410.00
IUUC-Sar-113361	Sorex araneus	65.02	0.00e+00	1053.00
IUUC-Ssc-115516	Sus scrofa	68.57	0.00e+00	1281.00
IUUC-Tgu-117386	Taeniopygia guttata	67.14	0.00e+00	1249.00
IUUC-Tru-117680	Takifugu rubripes	68.80	0.00e+00	1285.00
IUUC-Tsy-119137	Tarsius syrichta	68.33	0.00e+00	1265.00
IUUC-Tni-120537	Tetraodon nigroviridis	67.57	0.00e+00	1283.00
IUUC-Tbe-127862	Tupaia belangeri	59.67	0.00e+00	1033.00
IUUC-Ttr-128350	Tursiops truncatus	65.70	0.00e+00	1193.00
IUUC-Xtr-131946	Xenopus tropicalis	66.09	0.00e+00	1205.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence