iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cin-025550

Ensembl Protein ID

ENSCINP00000006320.3

UniProt Accession

F6RCR9; F6RCR9_CIOIN

Protein Name

Non-specific serine/threonine protein kinase

Gene Name

LOC100184788

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCING00000003124.3	ENSCINT00000006320.3	ENSCINP00000006320.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UBA	50.60	6.00e-127	451.00	IUUC-Ath-007014
UBD/Alpha-Helix/UBA	42.44	2.00e-107	384.00	IUUC-Spo-108202

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ciona intestinalis

Protein Sequence
(Fasta)

MASHSNEGRY VNIGGIKIGH YILGRTLGVG TFGKVKIATH QITGYQVAVK ILNRQKLKSL 60
DVVGKLKREI QNLKLFRHPH IIKLYQVICT PTDIFMVMEY VPGGELFDYI VKHGKLHENE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTATGGCTTC TCACAGTAAT GAAGGTCGTT ATGTAAACAT TGGTGGAATT AAAATCGGTC 60
ACTATATTCT TGGCCGTACG CTTGGGGTGG GAACTTTCGG CAAAGTGAAA ATTGCCACAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase

Interpro

IPR032270--AMPK_C
IPR028375--KA1/Ssp2_C
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST

Pfam

PF16579--AdenylateSensor
PF00069--Pkinase

SMART

SM00220--S_TKc

Gene Ontology

GO:0005737--C:cytoplasm
GO:0031588--C:nucleotide-activated protein kinase complex
GO:0005634--C:nucleus
GO:0004679--F:AMP-activated protein kinase activity
GO:0005524--F:ATP binding
GO:0035174--F:histone serine kinase activity
GO:0042149--P:cellular response to glucose starvation
GO:0035404--P:histone-serine phosphorylation
GO:0035556--P:intracellular signal transduction
GO:0032007--P:negative regulation of TOR signaling

KEGG

cin:100184788

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000134	Aegilops tauschii	45.66	2.00e-115	407.00
IUUC-Aml-001907	Ailuropoda melanoleuca	59.89	5.00e-177	612.00
IUUC-Atr-002770	Amborella trichopoda	48.99	5.00e-125	439.00
IUUC-Apl-003395	Anas platyrhynchos	57.57	0.00e+00	629.00
IUUC-Aca-004480	Anolis carolinensis	64.73	0.00e+00	655.00
IUUC-Aly-006289	Arabidopsis lyrata	50.60	6.00e-128	449.00
IUUC-Ath-007014	Arabidopsis thaliana	50.60	7.00e-129	452.00
IUUC-Ago-007957	Ashbya gossypii	46.50	2.00e-121	428.00
IUUC-Acl-008103	Aspergillus clavatus	53.76	3.00e-106	378.00
IUUC-Afl-008555	Aspergillus flavus	52.42	1.00e-107	382.00
IUUC-Afu-008949	Aspergillus fumigatus	53.15	1.00e-105	376.00
IUUC-Ani-009408	Aspergillus nidulans	54.84	7.00e-107	379.00
IUUC-Ang-009551	Aspergillus niger	54.49	2.00e-105	375.00
IUUC-Aor-010176	Aspergillus oryzae	52.42	1.00e-107	382.00
IUUC-Ate-010287	Aspergillus terreus	55.07	2.00e-106	378.00
IUUC-Ame-011019	Astyanax mexicanus	61.36	0.00e+00	670.00
IUUC-Bgr-012045	Blumeria graminis	45.24	2.00e-112	398.00
IUUC-Bta-012786	Bos taurus	59.89	4.00e-178	616.00
IUUC-Bci-013774	Botrytis cinerea	53.68	6.00e-110	390.00
IUUC-Bdi-014319	Brachypodium distachyon	48.00	1.00e-122	431.00
IUUC-Bol-016242	Brassica oleracea	49.80	9.00e-131	458.00
IUUC-Bra-016750	Brassica rapa	49.20	5.00e-130	456.00
IUUC-Cel-018518	Caenorhabditis elegans	55.04	3.00e-170	590.00
IUUC-Cja-019386	Callithrix jacchus	61.16	0.00e+00	676.00
IUUC-Cfa-020177	Canis familiaris	58.59	3.00e-172	596.00
IUUC-Cpo-021805	Cavia porcellus	61.16	0.00e+00	676.00
IUUC-Cre-022915	Chlamydomonas reinhardtii	53.89	4.00e-93	333.00
IUUC-Csa-024267	Chlorocebus sabaeus	61.43	0.00e+00	674.00
IUUC-Cho-024859	Choloepus hoffmanni	57.38	1.00e-168	585.00
IUUC-Csv-026139	Ciona savignyi	89.19	0.00e+00	1040.00
IUUC-Cgl-026480	Colletotrichum gloeosporioides	43.45	1.00e-65	243.00
IUUC-Cne-027044	Cryptococcus neoformans	50.00	2.00e-108	385.00
IUUC-Cme-027289	Cyanidioschyzon merolae	44.58	2.00e-111	394.00
IUUC-Dre-027749	Danio rerio	58.66	0.00e+00	641.00
IUUC-Dno-030006	Dasypus novemcinctus	59.89	4.00e-177	613.00
IUUC-Dor-030578	Dipodomys ordii	60.80	0.00e+00	672.00
IUUC-Dse-031507	Dothistroma septosporum	52.45	6.00e-112	397.00
IUUC-Dme-031704	Drosophila melanogaster	58.26	0.00e+00	631.00
IUUC-Ete-033055	Echinops telfairi	57.93	0.00e+00	627.00
IUUC-Eca-034016	Equus caballus	59.85	0.00e+00	633.00
IUUC-Fca-035754	Felis catus	57.86	7.00e-174	602.00
IUUC-Fal-037363	Ficedula albicollis	58.94	2.00e-176	610.00
IUUC-Fox-038073	Fusarium oxysporum	55.36	1.00e-107	382.00
IUUC-Fso-038236	Fusarium solani	54.37	6.00e-105	373.00
IUUC-Gmo-039633	Gadus morhua	57.67	0.00e+00	641.00
IUUC-Ggr-039987	Gaeumannomyces graminis	52.60	1.00e-105	375.00
IUUC-Gga-040546	Gallus gallus	60.00	0.00e+00	669.00
IUUC-Gac-041822	Gasterosteus aculeatus	59.24	0.00e+00	645.00
IUUC-Gma-042712	Glycine max	48.48	1.00e-127	448.00
IUUC-Ggo-045303	Gorilla gorilla	61.16	0.00e+00	676.00
IUUC-Hsa-045746	Homo sapiens	61.16	0.00e+00	676.00
IUUC-Hvu-047406	Hordeum vulgare	48.88	9.00e-125	438.00
IUUC-Itr-048134	Ictidomys tridecemlineatus	61.08	0.00e+00	677.00
IUUC-Kpa-049190	Komagataella pastoris	45.56	3.00e-119	420.00
IUUC-Lch-049623	Latimeria chalumnae	58.59	6.00e-175	605.00
IUUC-Lpe-051392	Leersia perrieri	46.93	2.00e-125	441.00
IUUC-Loc-052928	Lepisosteus oculatus	62.02	0.00e+00	681.00
IUUC-Lma-053054	Leptosphaeria maculans	44.80	4.00e-118	417.00
IUUC-Laf-053459	Loxodonta africana	60.54	0.00e+00	672.00
IUUC-Mcc-055862	Macaca mulatta	61.16	0.00e+00	676.00
IUUC-Mor-057170	Magnaporthe oryzae	50.64	2.00e-104	372.00
IUUC-Mpo-057302	Magnaporthe poae	53.02	6.00e-106	377.00
IUUC-Mtr-058309	Medicago truncatula	48.86	5.00e-125	439.00
IUUC-Mla-059058	Melampsora laricipopulina	59.09	8.00e-98	349.00
IUUC-Mga-059206	Meleagris gallopavo	59.00	0.00e+00	627.00
IUUC-Mvi-060337	Microbotryum violaceum	61.25	8.00e-101	360.00
IUUC-Mmr-061619	Microcebus murinus	61.24	0.00e+00	672.00
IUUC-Mdo-062160	Monodelphis domestica	61.19	0.00e+00	679.00
IUUC-Mmu-063406	Mus musculus	61.44	0.00e+00	679.00
IUUC-Mac-064518	Musa acuminata	45.49	5.00e-120	423.00
IUUC-Mpu-066326	Mustela putorius furo	59.77	0.00e+00	632.00
IUUC-Mlu-067968	Myotis lucifugus	60.15	3.00e-179	619.00
IUUC-Nfi-068493	Neosartorya fischeri	53.15	2.00e-105	375.00
IUUC-Ncr-068665	Neurospora crassa	44.66	2.00e-112	398.00
IUUC-Nle-070158	Nomascus leucogenys	61.16	0.00e+00	676.00
IUUC-Opr-070272	Ochotona princeps	57.47	7.00e-174	602.00
IUUC-Ont-071395	Oreochromis niloticus	60.75	0.00e+00	664.00
IUUC-Oan-073322	Ornithorhynchus anatinus	55.92	5.00e-168	582.00
IUUC-Ocu-074188	Oryctolagus cuniculus	58.39	2.00e-174	603.00
IUUC-Oba-075436	Oryza barthii	46.69	2.00e-125	441.00
IUUC-Obr-076507	Oryza brachyantha	48.10	2.00e-126	444.00
IUUC-Ogl-077718	Oryza glaberrima	51.28	2.00e-124	437.00
IUUC-Ogu-078349	Oryza glumaepatula	46.69	2.00e-125	441.00
IUUC-Oin-079889	Oryza indica	47.37	2.00e-125	441.00
IUUC-Olo-080521	Oryza longistaminata	46.69	2.00e-125	441.00
IUUC-Ome-081630	Oryza meridionalis	46.50	5.00e-125	439.00
IUUC-Oni-082211	Oryza nivara	46.69	7.00e-126	442.00
IUUC-Opu-083617	Oryza punctata	47.02	1.00e-125	441.00
IUUC-Oru-084252	Oryza rufipogon	46.69	1.00e-125	441.00
IUUC-Osa-085548	Oryza sativa	46.69	1.00e-125	441.00
IUUC-Ola-087169	Oryzias latipes	59.64	0.00e+00	659.00
IUUC-Olu-087861	Ostreococcus lucimarinus	49.43	6.00e-116	409.00
IUUC-Oga-088003	Otolemur garnettii	59.89	2.00e-177	613.00
IUUC-Oar-089933	Ovis aries	59.89	4.00e-178	616.00
IUUC-Ptr-090741	Pan troglodytes	61.16	0.00e+00	676.00
IUUC-Pan-092526	Papio anubis	59.89	1.00e-177	614.00
IUUC-Psi-094034	Pelodiscus sinensis	59.57	1.00e-175	608.00
IUUC-Pno-095030	Phaeosphaeria nodorum	52.15	3.00e-110	390.00
IUUC-Ppa-095615	Physcomitrella patens	49.78	3.00e-121	427.00
IUUC-Pfo-096295	Poecilia formosa	60.36	0.00e+00	661.00
IUUC-Pab-098023	Pongo abelii	61.16	0.00e+00	676.00
IUUC-Pop-100042	Populus trichocarpa	51.83	7.00e-128	449.00
IUUC-Pca-101104	Procavia capensis	66.93	5.00e-138	483.00
IUUC-Ppe-101642	Prunus persica	52.47	3.00e-125	440.00
IUUC-Pva-102470	Pteropus vampyrus	60.80	0.00e+00	665.00
IUUC-Pgr-103406	Puccinia graminis	61.74	6.00e-92	330.00
IUUC-Ptt-103713	Puccinia triticina	50.35	4.00e-73	267.00
IUUC-Pte-104259	Pyrenophora teres	51.51	6.00e-113	400.00
IUUC-Pyt-104752	Pyrenophora triticirepentis	52.01	8.00e-114	403.00
IUUC-Rno-104960	Rattus norvegicus	61.44	0.00e+00	681.00
IUUC-Sce-106290	Saccharomyces cerevisiae	43.31	4.00e-124	437.00
IUUC-Sha-107603	Sarcophilus harrisii	58.97	4.00e-177	612.00
IUUC-Sja-107772	Schizosaccharomyces japonicus	55.39	3.00e-108	384.00
IUUC-Spo-108202	Schizosaccharomyces pombe	42.44	2.00e-108	384.00
IUUC-Ssl-108535	Sclerotinia sclerotiorum	53.66	6.00e-110	390.00
IUUC-Smo-109309	Selaginella moellendorffii	47.19	3.00e-122	430.00
IUUC-Sit-109745	Setaria italica	52.57	2.00e-126	444.00
IUUC-Sly-110890	Solanum lycopersicum	49.10	3.00e-129	453.00
IUUC-Stu-112144	Solanum tuberosum	47.61	2.00e-122	431.00
IUUC-Sar-113521	Sorex araneus	50.96	4.00e-137	480.00
IUUC-Sbi-114764	Sorghum bicolor	48.28	3.00e-127	447.00
IUUC-Sre-115141	Sporisorium reilianum	66.79	1.00e-113	402.00
IUUC-Ssc-115732	Sus scrofa	58.89	4.00e-172	596.00
IUUC-Tgu-117190	Taeniopygia guttata	58.94	5.00e-176	609.00
IUUC-Tru-118735	Takifugu rubripes	60.36	0.00e+00	668.00
IUUC-Tsy-119503	Tarsius syrichta	59.46	1.00e-172	597.00
IUUC-Tni-119880	Tetraodon nigroviridis	59.64	0.00e+00	660.00
IUUC-Tca-121386	Theobroma cacao	49.09	3.00e-127	447.00
IUUC-Tre-122070	Trichoderma reesei	53.42	1.00e-107	382.00
IUUC-Tvi-122305	Trichoderma virens	50.37	3.00e-108	384.00
IUUC-Tae-123515	Triticum aestivum	48.98	6.00e-127	446.00
IUUC-Tur-126416	Triticum urartu	48.98	1.00e-123	435.00
IUUC-Tme-127174	Tuber melanosporum	41.67	2.00e-70	258.00
IUUC-Tbe-127791	Tupaia belangeri	68.42	2.00e-92	331.00
IUUC-Ttr-129224	Tursiops truncatus	58.01	1.00e-174	604.00
IUUC-Uma-129372	Ustilago maydis	66.79	3.00e-113	401.00
IUUC-Vda-129819	Verticillium dahliae	48.99	2.00e-88	318.00
IUUC-Vpa-130220	Vicugna pacos	59.92	0.00e+00	632.00
IUUC-Vvi-131649	Vitis vinifera	48.19	7.00e-128	449.00
IUUC-Xtr-132954	Xenopus tropicalis	62.09	0.00e+00	674.00
IUUC-Xma-134119	Xiphophorus maculatus	60.76	0.00e+00	661.00
IUUC-Yli-134422	Yarrowia lipolytica	46.98	2.00e-118	418.00
IUUC-Zma-135621	Zea mays	61.80	2.00e-119	421.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence