iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
dbPAF	PHOSIDA
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.70e-07	30.2	877	905

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtcla.f.sdtllvsGsdDgtikvWDl 30
           H+ +v+ +a + s   l+++s D +ik+W++
   Q: 877  HQKPVCRIAiWkS--QLITSSFDRSIKMWNW 905
           9999****97775..7**************7 PP

Organism

Caenorhabditis elegans

Protein Sequence
(Fasta)

MNDRVKIRWK EAKERIGNAY HDYGRLCAAH PKACLSMSLL TMIVLSYPTI TRLRLPVSTP 60
IDVFWSEHLH VNDKIAPFWI NENPASYIQQ FIVSTTISPW NATEMGPEHA VRAAIATAFR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATCTACATGA GAAAATAATT TTGAAAAAAT CGATAAAAAA TGAACGATCG AGTGAAAATT 60
CGATGGAAGG AGGCTAAGGA GAGAATTGGA AACGCATATC ACGATTATGG ACGGTAAATA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0853--WD repeat

Interpro

IPR030225--SCAP
IPR000731--SSD
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50156--SSD
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12349--Sterol-sensing

SMART

SM00320--WD40

Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0000139--C:Golgi membrane
GO:0016021--C:integral component of membrane
GO:0015485--F:cholesterol binding
GO:0008203--P:cholesterol metabolic process
GO:0032933--P:SREBP signaling pathway

KEGG

cel:CELE_D2013.8

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001802	Ailuropoda melanoleuca	29.59	5.00e-60	225.00
IUUC-Apl-003294	Anas platyrhynchos	26.14	1.00e-67	250.00
IUUC-Aca-004424	Anolis carolinensis	25.14	1.00e-57	217.00
IUUC-Bta-013478	Bos taurus	29.08	3.00e-60	226.00
IUUC-Cja-019123	Callithrix jacchus	27.93	7.00e-53	201.00
IUUC-Cfa-021082	Canis familiaris	29.59	2.00e-60	227.00
IUUC-Cpo-022477	Cavia porcellus	27.17	5.00e-62	231.00
IUUC-Csa-023176	Chlorocebus sabaeus	28.70	6.00e-67	248.00
IUUC-Cin-025490	Ciona intestinalis	27.54	5.00e-45	175.00
IUUC-Csv-026115	Ciona savignyi	28.19	9.00e-58	218.00
IUUC-Dre-028008	Danio rerio	25.64	7.00e-67	248.00
IUUC-Dno-028887	Dasypus novemcinctus	29.51	5.00e-61	228.00
IUUC-Dor-030467	Dipodomys ordii	30.96	4.00e-53	202.00
IUUC-Dme-032087	Drosophila melanogaster	22.18	7.00e-65	241.00
IUUC-Ete-032372	Echinops telfairi	29.01	8.00e-24	105.00
IUUC-Eca-033896	Equus caballus	29.93	7.00e-62	231.00
IUUC-Eeu-035099	Erinaceus europaeus	28.54	3.00e-40	159.00
IUUC-Fca-035616	Felis catus	29.76	9.00e-61	228.00
IUUC-Fal-037231	Ficedula albicollis	31.56	1.00e-54	207.00
IUUC-Gmo-039439	Gadus morhua	30.96	4.00e-56	212.00
IUUC-Gac-041516	Gasterosteus aculeatus	29.02	3.00e-58	219.00
IUUC-Hsa-046674	Homo sapiens	29.25	2.00e-60	226.00
IUUC-Itr-048879	Ictidomys tridecemlineatus	29.18	2.00e-62	233.00
IUUC-Lch-049689	Latimeria chalumnae	25.15	6.00e-59	221.00
IUUC-Loc-052417	Lepisosteus oculatus	24.16	3.00e-06	45.80
IUUC-Laf-053795	Loxodonta africana	29.44	2.00e-62	233.00
IUUC-Mcc-055502	Macaca mulatta	29.42	6.00e-61	228.00
IUUC-Mga-059805	Meleagris gallopavo	29.05	1.00e-58	220.00
IUUC-Mmr-060997	Microcebus murinus	29.27	3.00e-62	232.00
IUUC-Mdo-062940	Monodelphis domestica	28.69	4.00e-61	229.00
IUUC-Mmu-063255	Mus musculus	29.71	3.00e-63	236.00
IUUC-Mpu-066158	Mustela putorius furo	29.76	1.00e-61	230.00
IUUC-Mlu-067201	Myotis lucifugus	29.00	6.00e-55	208.00
IUUC-Nle-069145	Nomascus leucogenys	29.25	6.00e-59	221.00
IUUC-Opr-070797	Ochotona princeps	32.86	5.00e-28	119.00
IUUC-Ont-071553	Oreochromis niloticus	28.30	6.00e-59	221.00
IUUC-Ocu-074598	Oryctolagus cuniculus	29.37	1.00e-61	230.00
IUUC-Oar-089287	Ovis aries	27.99	3.00e-61	229.00
IUUC-Pan-092004	Papio anubis	29.42	7.00e-61	228.00
IUUC-Psi-093028	Pelodiscus sinensis	29.29	5.00e-60	225.00
IUUC-Pma-094145	Petromyzon marinus	30.52	3.00e-69	256.00
IUUC-Pfo-096320	Poecilia formosa	31.29	2.00e-57	217.00
IUUC-Pab-097862	Pongo abelii	29.25	2.00e-60	226.00
IUUC-Pca-100862	Procavia capensis	29.65	3.00e-32	132.00
IUUC-Pva-103050	Pteropus vampyrus	29.93	3.00e-58	219.00
IUUC-Rno-105852	Rattus norvegicus	29.54	5.00e-63	235.00
IUUC-Sha-107312	Sarcophilus harrisii	27.37	4.00e-61	229.00
IUUC-Sar-113311	Sorex araneus	25.71	1.00e-14	74.30
IUUC-Ssc-116356	Sus scrofa	28.76	9.00e-62	231.00
IUUC-Tgu-116896	Taeniopygia guttata	26.19	3.00e-09	56.60
IUUC-Tru-118197	Takifugu rubripes	30.79	7.00e-55	208.00
IUUC-Tni-119823	Tetraodon nigroviridis	26.88	3.00e-67	249.00
IUUC-Ttr-129164	Tursiops truncatus	26.68	2.00e-62	233.00
IUUC-Xtr-132819	Xenopus tropicalis	32.14	4.00e-60	225.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence