iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMUSG00000033285.15	ENSMUST00000052120.13	ENSMUSP00000060613.7
ENSMUSG00000033285.15	ENSMUST00000125059.5	ENSMUSP00000135731.1
ENSMUSG00000033285.15	ENSMUST00000197602.1	ENSMUSP00000143010.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	GXD
DNA & RNA Element
AREsite	microRNA	TRANSFAC	RepTar
miRNAMap	RAID2
Protein-protein Interaction
IID	iRefIndex	PINA	HINT
Post-translational Modifications (PTMs)
dbPAF	PhosphositePlus	dbPTM	UniProt
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.00e-41	138.7	588	626
UBD/Beta-Prp	9.80e-97	324.8	36	274

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gH+ +v c++  +d  l+++Gs D ++k+W l+ g++ +
   Q: 588  GHKLPVLCMDIsHDgALIATGSADRNVKIWGLDFGDCHR 626
           79999******977799*******************977 PP

UBD/Beta-Prp

   S: 22   ksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklv 110
           ++++a+    + + +wd+++g ++  l+g+++evt+++ spdg  l+ g eD++i++++l +g+  +t++gh++ v+sl++++ g +l+
   Q: 36   GRYVAVPA-CEHVFIWDLRKGEKILILQGNKQEVTCLCPSPDGLHLAVGYEDGAIRIFSLLSGEGNITFNGHKAAVTSLKYDQLGGRLA 123
           55555553.577889****************************9********************************************* PP
   S: 111  sGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgs 199
           sGs+d  + +wd+ +++ l+  l+gh+++v+ + +  + nllv++++D++v++Wdl ++ + +t+ g h   v  l + s+ k+l++g+
   Q: 124  SGSKDTDVIIWDVINESGLY-RLKGHKDAVTQALFLRERNLLVTSGKDTMVKWWDLDNQHCFKTMVG-HRTEVWGLVLVSEEKRLITGA 210
           *******************9.9***************9***************************99.*********9999******** PP
   S: 200  ldgtvklwdlq...........tgecvrtlnghtdnvksvrfs......pnderlvsgssDgsi 246
            d+ ++ wd+            + + ++++ g +d++ s + +      + ++r++s+s+ gsi
   Q: 211  ADSELRAWDIDylqeiddpeepEPKKIKECPGIQDTPESEDSTleaddeKSEDRILSCSKAGSI 274
           **********999999998888777788888888777776666555555666777777777766 PP

Organism

Mus musculus

Protein Sequence
(Fasta)

MGLTKQYLRY VASAVFGLIG SQKGNIVFVT LRGEKGRYVA VPACEHVFIW DLRKGEKILI 60
LQGNKQEVTC LCPSPDGLHL AVGYEDGAIR IFSLLSGEGN ITFNGHKAAV TSLKYDQLGG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AATCGGACCG GAAGTGGCGG GTCTCGTAGG CAGCGCTGTC TGCTGGAGCC TCGTGGAGAG 60
TGAGGTGAGT GTTGCTGGCT CTTTAGGGAT CGCGGGGCGC GGTTCCCCGC ACAGTGGTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR011047--Quinoprotein_ADH-like_supfam
IPR007148--SSU_processome_Utp12
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04003--Utp12
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0031965--C:nuclear membrane
GO:0005730--C:nucleolus
GO:0005634--C:nucleus
GO:0034388--C:Pwp2p-containing subcomplex of 90S preribosome
GO:0032040--C:small-subunit processome
GO:0003723--F:RNA binding
GO:0030515--F:snoRNA binding
GO:0000462--P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

KEGG

mmu:269470

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000784	Aegilops tauschii	37.77	2.00e-151	530.00
IUUC-Aml-001245	Ailuropoda melanoleuca	89.94	0.00e+00	1612.00
IUUC-Atr-002700	Amborella trichopoda	38.20	1.00e-168	587.00
IUUC-Apl-004164	Anas platyrhynchos	77.27	0.00e+00	1067.00
IUUC-Aca-004765	Anolis carolinensis	72.79	0.00e+00	1362.00
IUUC-Aly-006503	Arabidopsis lyrata	40.02	2.00e-177	616.00
IUUC-Ath-006848	Arabidopsis thaliana	39.51	9.00e-180	624.00
IUUC-Ago-007909	Ashbya gossypii	35.01	2.00e-147	516.00
IUUC-Acl-008238	Aspergillus clavatus	39.36	0.00e+00	633.00
IUUC-Afl-008544	Aspergillus flavus	39.39	9.00e-179	620.00
IUUC-Afu-008868	Aspergillus fumigatus	38.96	6.00e-180	624.00
IUUC-Ani-009367	Aspergillus nidulans	39.09	4.00e-175	608.00
IUUC-Ang-009732	Aspergillus niger	39.12	0.00e+00	629.00
IUUC-Aor-010140	Aspergillus oryzae	39.46	2.00e-179	623.00
IUUC-Ate-010572	Aspergillus terreus	39.02	8.00e-179	621.00
IUUC-Ame-010956	Astyanax mexicanus	72.37	0.00e+00	806.00
IUUC-Bgr-012296	Blumeria graminis	37.56	2.00e-174	606.00
IUUC-Bta-012716	Bos taurus	91.10	0.00e+00	1660.00
IUUC-Bci-013699	Botrytis cinerea	37.17	5.00e-164	572.00
IUUC-Bdi-014525	Brachypodium distachyon	37.63	4.00e-161	561.00
IUUC-Bol-015117	Brassica oleracea	39.48	5.00e-175	608.00
IUUC-Bra-016869	Brassica rapa	39.16	2.00e-175	609.00
IUUC-Cel-018570	Caenorhabditis elegans	34.13	3.00e-130	459.00
IUUC-Cja-019425	Callithrix jacchus	89.64	0.00e+00	1607.00
IUUC-Cfa-020787	Canis familiaris	89.62	0.00e+00	1620.00
IUUC-Cpo-021729	Cavia porcellus	91.47	0.00e+00	1159.00
IUUC-Cre-022678	Chlamydomonas reinhardtii	42.64	1.00e-106	380.00
IUUC-Csa-024098	Chlorocebus sabaeus	90.89	0.00e+00	1626.00
IUUC-Cho-024495	Choloepus hoffmanni	76.04	0.00e+00	903.00
IUUC-Cin-025245	Ciona intestinalis	49.23	3.00e-170	591.00
IUUC-Cgl-026708	Colletotrichum gloeosporioides	38.73	6.00e-168	585.00
IUUC-Cne-026835	Cryptococcus neoformans	45.38	6.00e-125	442.00
IUUC-Cme-027162	Cyanidioschyzon merolae	29.49	3.00e-41	164.00
IUUC-Dre-027874	Danio rerio	69.52	0.00e+00	1274.00
IUUC-Dno-028905	Dasypus novemcinctus	89.30	0.00e+00	1613.00
IUUC-Dor-030383	Dipodomys ordii	87.00	0.00e+00	806.00
IUUC-Dse-031297	Dothistroma septosporum	36.81	2.00e-165	576.00
IUUC-Dme-031956	Drosophila melanogaster	42.66	0.00e+00	676.00
IUUC-Ete-032608	Echinops telfairi	81.03	0.00e+00	894.00
IUUC-Eca-034181	Equus caballus	89.94	0.00e+00	1592.00
IUUC-Eeu-034495	Erinaceus europaeus	89.47	0.00e+00	1543.00
IUUC-Fca-035994	Felis catus	90.25	0.00e+00	1514.00
IUUC-Fal-036611	Ficedula albicollis	75.90	0.00e+00	1322.00
IUUC-Fox-037807	Fusarium oxysporum	37.62	1.00e-169	590.00
IUUC-Fso-038090	Fusarium solani	37.62	3.00e-166	579.00
IUUC-Gmo-039018	Gadus morhua	63.50	0.00e+00	693.00
IUUC-Ggr-039748	Gaeumannomyces graminis	37.84	2.00e-171	596.00
IUUC-Gga-040707	Gallus gallus	76.33	0.00e+00	1346.00
IUUC-Gac-042334	Gasterosteus aculeatus	63.54	0.00e+00	685.00
IUUC-Gma-043860	Glycine max	38.16	2.00e-169	589.00
IUUC-Ggo-045334	Gorilla gorilla	89.32	0.00e+00	1585.00
IUUC-Hsa-046996	Homo sapiens	90.89	0.00e+00	1588.00
IUUC-Hvu-047381	Hordeum vulgare	34.50	7.00e-88	318.00
IUUC-Itr-047938	Ictidomys tridecemlineatus	90.47	0.00e+00	1603.00
IUUC-Kpa-049185	Komagataella pastoris	34.73	2.00e-151	530.00
IUUC-Lch-050098	Latimeria chalumnae	66.81	0.00e+00	1130.00
IUUC-Lpe-050710	Leersia perrieri	37.16	2.00e-166	580.00
IUUC-Loc-052745	Lepisosteus oculatus	68.64	0.00e+00	1191.00
IUUC-Lma-053104	Leptosphaeria maculans	38.73	4.00e-176	613.00
IUUC-Laf-054395	Loxodonta africana	88.77	0.00e+00	1580.00
IUUC-Mcc-055077	Macaca mulatta	90.89	0.00e+00	1620.00
IUUC-Meu-056418	Macropus eugenii	79.53	0.00e+00	723.00
IUUC-Mor-057031	Magnaporthe oryzae	37.87	3.00e-156	546.00
IUUC-Mpo-057420	Magnaporthe poae	37.61	3.00e-168	585.00
IUUC-Mtr-057838	Medicago truncatula	38.23	0.00e+00	628.00
IUUC-Mla-058854	Melampsora laricipopulina	37.21	1.00e-156	547.00
IUUC-Mga-060120	Meleagris gallopavo	72.19	0.00e+00	1241.00
IUUC-Mvi-060407	Microbotryum violaceum	45.62	4.00e-137	482.00
IUUC-Mmr-060635	Microcebus murinus	89.19	0.00e+00	1590.00
IUUC-Mdo-063023	Monodelphis domestica	84.31	0.00e+00	1547.00
IUUC-Mac-065569	Musa acuminata	38.67	1.00e-170	593.00
IUUC-Mpu-066462	Mustela putorius furo	89.94	0.00e+00	1624.00
IUUC-Mlu-067894	Myotis lucifugus	89.83	0.00e+00	1627.00
IUUC-Nfi-068321	Neosartorya fischeri	39.05	6.00e-179	621.00
IUUC-Ncr-068661	Neurospora crassa	37.75	2.00e-167	583.00
IUUC-Nle-069409	Nomascus leucogenys	90.36	0.00e+00	1590.00
IUUC-Opr-070445	Ochotona princeps	86.48	0.00e+00	985.00
IUUC-Ont-072339	Oreochromis niloticus	69.16	0.00e+00	1235.00
IUUC-Oan-073688	Ornithorhynchus anatinus	75.92	0.00e+00	1349.00
IUUC-Ocu-074227	Oryctolagus cuniculus	90.57	0.00e+00	1643.00
IUUC-Oba-075635	Oryza barthii	36.53	4.00e-157	548.00
IUUC-Obr-076897	Oryza brachyantha	37.85	4.00e-169	588.00
IUUC-Ogl-077555	Oryza glaberrima	36.42	9.00e-157	547.00
IUUC-Ogu-078724	Oryza glumaepatula	36.53	5.00e-158	551.00
IUUC-Oin-080030	Oryza indica	36.53	4.00e-157	548.00
IUUC-Olo-080687	Oryza longistaminata	34.68	8.00e-146	511.00
IUUC-Ome-081867	Oryza meridionalis	36.95	3.00e-159	556.00
IUUC-Oni-082559	Oryza nivara	36.53	4.00e-157	548.00
IUUC-Opu-083332	Oryza punctata	38.12	2.00e-147	516.00
IUUC-Oru-084455	Oryza rufipogon	36.53	4.00e-157	549.00
IUUC-Osa-085793	Oryza sativa	36.53	4.00e-157	549.00
IUUC-Ola-087395	Oryzias latipes	68.25	0.00e+00	1144.00
IUUC-Olu-087768	Ostreococcus lucimarinus	37.25	5.00e-155	541.00
IUUC-Oga-088574	Otolemur garnettii	90.04	0.00e+00	1625.00
IUUC-Oar-089453	Ovis aries	89.32	0.00e+00	1647.00
IUUC-Ptr-090694	Pan troglodytes	90.68	0.00e+00	1583.00
IUUC-Pan-092420	Papio anubis	90.59	0.00e+00	1613.00
IUUC-Psi-093683	Pelodiscus sinensis	80.66	0.00e+00	1464.00
IUUC-Pma-094197	Petromyzon marinus	56.58	8.00e-72	263.00
IUUC-Pno-094783	Phaeosphaeria nodorum	38.22	8.00e-174	604.00
IUUC-Ppa-095208	Physcomitrella patens	39.57	4.00e-172	598.00
IUUC-Pfo-096299	Poecilia formosa	68.36	0.00e+00	1238.00
IUUC-Pab-098706	Pongo abelii	90.88	0.00e+00	1597.00
IUUC-Pop-099275	Populus trichocarpa	38.47	5.00e-172	598.00
IUUC-Pca-100796	Procavia capensis	75.00	0.00e+00	1201.00
IUUC-Ppe-101861	Prunus persica	40.23	1.00e-179	623.00
IUUC-Pva-103241	Pteropus vampyrus	83.77	0.00e+00	1441.00
IUUC-Pgr-103432	Puccinia graminis	36.14	8.00e-151	528.00
IUUC-Ptt-103742	Puccinia triticina	39.18	1.00e-100	361.00
IUUC-Pte-104069	Pyrenophora teres	38.09	3.00e-165	576.00
IUUC-Pyt-104650	Pyrenophora triticirepentis	37.98	5.00e-173	602.00
IUUC-Rno-105219	Rattus norvegicus	96.07	0.00e+00	1694.00
IUUC-Sce-106271	Saccharomyces cerevisiae	36.02	3.00e-158	552.00
IUUC-Sha-107550	Sarcophilus harrisii	84.40	0.00e+00	1541.00
IUUC-Sja-107664	Schizosaccharomyces japonicus	38.32	2.00e-163	570.00
IUUC-Spo-108239	Schizosaccharomyces pombe	38.36	2.00e-171	596.00
IUUC-Ssl-108626	Sclerotinia sclerotiorum	38.24	2.00e-170	592.00
IUUC-Smo-109477	Selaginella moellendorffii	38.85	2.00e-169	590.00
IUUC-Sit-110000	Setaria italica	38.44	7.00e-159	554.00
IUUC-Sly-111595	Solanum lycopersicum	38.62	4.00e-177	615.00
IUUC-Stu-112516	Solanum tuberosum	38.92	2.00e-177	616.00
IUUC-Sar-113195	Sorex araneus	80.83	0.00e+00	1282.00
IUUC-Sbi-114465	Sorghum bicolor	36.81	1.00e-165	577.00
IUUC-Sre-115006	Sporisorium reilianum	34.83	4.00e-149	522.00
IUUC-Ssc-115929	Sus scrofa	89.09	0.00e+00	1576.00
IUUC-Tgu-117282	Taeniopygia guttata	76.11	0.00e+00	1322.00
IUUC-Tru-118406	Takifugu rubripes	68.11	0.00e+00	1189.00
IUUC-Tsy-119170	Tarsius syrichta	88.36	0.00e+00	1604.00
IUUC-Tni-119721	Tetraodon nigroviridis	66.88	0.00e+00	1162.00
IUUC-Tca-121761	Theobroma cacao	39.32	0.00e+00	628.00
IUUC-Tre-121908	Trichoderma reesei	36.42	7.00e-164	571.00
IUUC-Tvi-122547	Trichoderma virens	37.27	5.00e-168	585.00
IUUC-Tae-125496	Triticum aestivum	38.53	1.00e-163	570.00
IUUC-Tur-126811	Triticum urartu	40.05	1.00e-163	570.00
IUUC-Tme-126987	Tuber melanosporum	39.04	1.00e-178	620.00
IUUC-Tbe-127315	Tupaia belangeri	91.00	0.00e+00	856.00
IUUC-Ttr-129165	Tursiops truncatus	80.72	0.00e+00	1383.00
IUUC-Uma-129651	Ustilago maydis	35.29	2.00e-150	527.00
IUUC-Vda-129973	Verticillium dahliae	38.36	1.00e-162	567.00
IUUC-Vpa-130163	Vicugna pacos	78.10	0.00e+00	684.00
IUUC-Vvi-131402	Vitis vinifera	37.29	1.00e-175	610.00
IUUC-Xtr-132296	Xenopus tropicalis	72.71	0.00e+00	1306.00
IUUC-Xma-133028	Xiphophorus maculatus	68.43	0.00e+00	1241.00
IUUC-Yli-134484	Yarrowia lipolytica	38.16	8.00e-155	541.00
IUUC-Zma-135938	Zea mays	34.96	3.00e-148	519.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence