iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSNLEG00000011671.2	ENSNLET00000014910.2	ENSNLEP00000014215.1
ENSNLEG00000011671.2	ENSNLET00000014911.2	ENSNLEP00000014216.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.70e-25	88.0	153	190
UBD/Beta-Prp	2.70e-52	177.8	495	753

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGs..dDgtikvWDlrtgv 34
           gH+ +v c+af ++ +++vs +  +D ++ vWD++++ 
   Q: 153  GHKYGVACVAFsPNmKYIVSMGyqHDMVLNVWDWKKDI 190
           89**********888*****9989*********98765 PP

UBD/Beta-Prp

   S: 13   itcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgk...ilvtgseDrtikvwdls.tgkcvhtlkghedsv 97
           ++++++spd+++la+g r+g ++ + ++ ++ l +++ h+aev ++++s+ +    +l+++s+Dr+i+v +++ ++   +tl  h++s+
   Q: 495  VRVMQVSPDGQHLASGDRSGNLRQHCLHFMDELVKVEAHDAEVLCLEYSKPETgltLLASASRDRLIHVLNVEkNYNLEQTLDDHSSSI 583
           67899*******************************************99887899***************997888999********* PP
   S: 98   lslsfspsg.dklvsGshdrtirvwdletgqclee....tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl...ktgkllrtltgg 178
           ++++f  ++   ++s ++d+ i     ++g+   +        ++ +   + ++ ++++++ ++ Dr vr+++    k++k+ +  +g 
   Q: 584  TAIKFAGNRdIQMISCGADKSIYFRSAQQGSDGLHfvrtHHVAEKTTLYDMDIDITQKYVAVACQDRNVRVYNTvngKQKKCYKGSQG- 671
           *******885789********998666666655545332112222233446677778****************988888888888898. PP
   S: 179  htdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriW.......dlrs 253
           +++s  ++ +d++g++l++   d+++ + d+ +gec+ ++ gh++ ++s++f+ + ++l+++s D  ++iW       ++ +
   Q: 672  DEGSLLKVHVDPSGTFLATSCSDKSISVIDFYSGECIAKMFGHSEIITSMKFTYDCHHLITVSGDSCVFIWhlgpeitNCMK 753
           999999999**************************************************************66554444443 PP

Organism

Nomascus leucogenys

Protein Sequence
(Fasta)

MAAVGSGGYA RNDAGEKLPS VMAGVPARRG QSSPPPAPPL CLRRRTRLST ASEETVQNRV 60
SLEKVLGITA QNSSGLTCDP GTGHVAYLAG CVVVILDPKE NKQQHIFNTA RKSLSALAFS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGTCATGTGA CGAATGGGCC ATAGCGAGTA CTGTGCGCCT GCGCAAAGCC GGCCCTTGGC 60
CACCCCGATT TTCATCACGT GTTGGGGGAA GGGCGGTGTC AGGCGTTTCT GAGCCTGCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
IPR030545--WDR62

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005813--C:centrosome
GO:0005634--C:nucleus
GO:0000922--C:spindle pole
GO:0007099--P:centriole replication
GO:0021987--P:cerebral cortex development
GO:0007052--P:mitotic spindle organization
GO:0022008--P:neurogenesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001371	Ailuropoda melanoleuca	84.49	0.00e+00	1939.00
IUUC-Aca-004935	Anolis carolinensis	70.85	0.00e+00	1000.00
IUUC-Afu-008757	Aspergillus fumigatus	21.72	8.00e-30	125.00
IUUC-Bta-013336	Bos taurus	84.93	0.00e+00	1901.00
IUUC-Cel-018592	Caenorhabditis elegans	28.78	6.00e-73	270.00
IUUC-Cja-019094	Callithrix jacchus	92.21	0.00e+00	2074.00
IUUC-Cfa-020529	Canis familiaris	87.04	0.00e+00	1971.00
IUUC-Cpo-021970	Cavia porcellus	86.46	0.00e+00	1642.00
IUUC-Cre-022999	Chlamydomonas reinhardtii	27.70	4.00e-13	70.10
IUUC-Csa-024161	Chlorocebus sabaeus	92.24	0.00e+00	2112.00
IUUC-Cho-024310	Choloepus hoffmanni	84.08	0.00e+00	1149.00
IUUC-Cgl-026454	Colletotrichum gloeosporioides	22.71	1.00e-22	102.00
IUUC-Dno-029933	Dasypus novemcinctus	77.16	0.00e+00	1729.00
IUUC-Dor-031147	Dipodomys ordii	79.38	0.00e+00	1826.00
IUUC-Dse-031501	Dothistroma septosporum	30.71	4.00e-22	100.00
IUUC-Eca-033675	Equus caballus	85.58	0.00e+00	1934.00
IUUC-Fca-035826	Felis catus	83.65	0.00e+00	1975.00
IUUC-Ggo-045152	Gorilla gorilla	97.75	0.00e+00	2137.00
IUUC-Hsa-045891	Homo sapiens	97.84	0.00e+00	2162.00
IUUC-Itr-048019	Ictidomys tridecemlineatus	91.70	0.00e+00	1545.00
IUUC-Lch-049669	Latimeria chalumnae	52.49	0.00e+00	1025.00
IUUC-Loc-052488	Lepisosteus oculatus	55.70	0.00e+00	1018.00
IUUC-Laf-053992	Loxodonta africana	82.06	0.00e+00	1924.00
IUUC-Mcc-054994	Macaca mulatta	96.97	0.00e+00	2104.00
IUUC-Meu-056815	Macropus eugenii	78.37	0.00e+00	1401.00
IUUC-Mmr-060693	Microcebus murinus	79.23	0.00e+00	1862.00
IUUC-Mdo-063007	Monodelphis domestica	72.24	0.00e+00	1611.00
IUUC-Mmu-064067	Mus musculus	81.09	0.00e+00	1876.00
IUUC-Mpu-066532	Mustela putorius furo	85.16	0.00e+00	1981.00
IUUC-Mlu-066982	Myotis lucifugus	82.60	0.00e+00	1821.00
IUUC-Opr-070397	Ochotona princeps	84.02	0.00e+00	1873.00
IUUC-Ocu-074274	Oryctolagus cuniculus	85.00	0.00e+00	1894.00
IUUC-Oga-088577	Otolemur garnettii	83.89	0.00e+00	1915.00
IUUC-Oar-090117	Ovis aries	83.09	0.00e+00	1820.00
IUUC-Ptr-090553	Pan troglodytes	96.60	0.00e+00	2189.00
IUUC-Pan-092559	Papio anubis	95.21	0.00e+00	915.00
IUUC-Psi-093710	Pelodiscus sinensis	63.49	0.00e+00	1366.00
IUUC-Pab-098510	Pongo abelii	94.41	0.00e+00	2130.00
IUUC-Pca-100323	Procavia capensis	71.12	0.00e+00	1319.00
IUUC-Pva-102895	Pteropus vampyrus	84.96	0.00e+00	1959.00
IUUC-Rno-105598	Rattus norvegicus	82.15	0.00e+00	1884.00
IUUC-Sha-107013	Sarcophilus harrisii	75.04	0.00e+00	1634.00
IUUC-Sar-113261	Sorex araneus	81.66	0.00e+00	1816.00
IUUC-Ssc-115317	Sus scrofa	84.93	0.00e+00	1869.00
IUUC-Tsy-118799	Tarsius syrichta	91.25	0.00e+00	858.00
IUUC-Tme-127128	Tuber melanosporum	23.65	9.00e-32	132.00
IUUC-Tbe-127555	Tupaia belangeri	92.87	0.00e+00	1008.00
IUUC-Ttr-128722	Tursiops truncatus	82.81	0.00e+00	1866.00
IUUC-Vpa-130392	Vicugna pacos	68.14	5.00e-107	382.00
IUUC-Xtr-131789	Xenopus tropicalis	59.39	0.00e+00	979.00
IUUC-Yli-134437	Yarrowia lipolytica	25.97	1.00e-15	78.60

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence