iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMUSG00000038299.15	ENSMUST00000166214.7	ENSMUSP00000132189.1
ENSMUSG00000038299.15	ENSMUST00000053663.9	ENSMUSP00000052465.9

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	GXD
DNA & RNA Element
microRNA	TRANSFAC	RepTar	RAID2
Protein-protein Interaction
IID	HINT
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.90e-21	75.4	568	604
UBD/Beta-Prp	2.20e-49	169.4	439	608

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           gH + ++++ f +d + l+s++ D++++ WDl +g l
   Q: 568  GHHGQINDMTFsPDgRWLISAAMDCSVRTWDLPSGCL 604
           7999********99999***************99976 PP

UBD/Beta-Prp

   S: 89   tlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee..tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl 175
           t +  + +++++++   g++ ++G +   + v+++++g    +   ++ h+g+v++v+v++ ++l+v+++  r +++W+ k++ l++ l
   Q: 439  TNS--NLTATAVDITSCGNFAIIGLSSGAVDVYNMQSGIHRGNfgDDKAHTGSVRGVAVDGLNQLVVTAGSERLLKFWNFKSKVLIHSL 525
           333..3344445555566999****************9988878899****************************************** PP
   S: 176  tgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktl 260
            g  ++s + + +++++  l  + +d ++ + d++t ++vr++ gh  +++++ fsp++ +l+s+++D s+r Wdl sg l+ ++
   Q: 526  -G-LDSSPNMMLLHRDSGILGLAMDDFSIAVLDIETRKIVREFSGHHGQINDMTFSPDGRWLISAAMDCSVRTWDLPSGCLIDCF 608
           .4.799999999****************************************************************999777766 PP

Organism

Mus musculus

Protein Sequence
(Fasta)

MAEMESAVEG RTASVLFAGF RALGLFSNEV PHVVRYSALK RRFYVTTCVG KSFHTYDVQK 60
LSLVAVSNSV PQDICCMAAD GRLVFAAYGN VFSAFARNKE IVHTFKGHKA EIHLLQPFGD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCGTTTTGTG TTACACCGAA GGCGGTCCGT TCCTGTACCA TCGGCTCCGG ATCCCGGAAG 60
CACGCCTCGC TCTCCTGCTC CGGCACGGGC TCTTCCTGGG GCGTGTTGCG GCTCTCCTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR011047--Quinoprotein_ADH-like_supfam
IPR007319--SSU_processome_Utp21
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF04192--Utp21
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005730--C:nucleolus
GO:0034388--C:Pwp2p-containing subcomplex of 90S preribosome
GO:0032040--C:small-subunit processome
GO:0003723--F:RNA binding
GO:0030516--P:regulation of axon extension
GO:0001895--P:retina homeostasis
GO:0006364--P:rRNA processing

KEGG

mmu:225348

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001096	Aegilops tauschii	36.73	3.00e-150	525.00
IUUC-Aml-002289	Ailuropoda melanoleuca	88.74	0.00e+00	1612.00
IUUC-Atr-002859	Amborella trichopoda	33.68	1.00e-128	454.00
IUUC-Apl-003505	Anas platyrhynchos	72.19	0.00e+00	1186.00
IUUC-Aca-004339	Anolis carolinensis	70.52	0.00e+00	1273.00
IUUC-Aly-005913	Arabidopsis lyrata	36.43	8.00e-155	541.00
IUUC-Ath-006767	Arabidopsis thaliana	36.58	7.00e-158	551.00
IUUC-Ago-007763	Ashbya gossypii	32.67	3.00e-119	423.00
IUUC-Acl-008275	Aspergillus clavatus	33.66	8.00e-94	338.00
IUUC-Afl-008457	Aspergillus flavus	33.43	2.00e-93	337.00
IUUC-Afu-008914	Aspergillus fumigatus	33.58	1.00e-103	371.00
IUUC-Ani-009225	Aspergillus nidulans	32.28	2.00e-102	367.00
IUUC-Aor-010046	Aspergillus oryzae	32.17	2.00e-117	417.00
IUUC-Ate-010337	Aspergillus terreus	32.21	2.00e-116	414.00
IUUC-Ame-010963	Astyanax mexicanus	65.81	0.00e+00	1199.00
IUUC-Bgr-011973	Blumeria graminis	30.12	6.00e-112	399.00
IUUC-Bta-012462	Bos taurus	88.32	0.00e+00	1584.00
IUUC-Bci-013940	Botrytis cinerea	30.49	8.00e-113	402.00
IUUC-Bdi-014725	Brachypodium distachyon	36.31	2.00e-153	536.00
IUUC-Bol-016534	Brassica oleracea	35.99	1.00e-152	533.00
IUUC-Bra-016781	Brassica rapa	35.67	2.00e-150	526.00
IUUC-Cel-018581	Caenorhabditis elegans	27.92	6.00e-90	325.00
IUUC-Cja-019675	Callithrix jacchus	88.62	0.00e+00	1621.00
IUUC-Cfa-020118	Canis familiaris	87.44	0.00e+00	1561.00
IUUC-Cpo-021798	Cavia porcellus	88.69	0.00e+00	1573.00
IUUC-Cre-022566	Chlamydomonas reinhardtii	29.00	5.00e-26	112.00
IUUC-Csa-023547	Chlorocebus sabaeus	88.86	0.00e+00	1597.00
IUUC-Cho-024518	Choloepus hoffmanni	77.53	0.00e+00	1240.00
IUUC-Cin-025339	Ciona intestinalis	46.68	0.00e+00	795.00
IUUC-Cgl-026476	Colletotrichum gloeosporioides	30.47	1.00e-113	404.00
IUUC-Cne-026859	Cryptococcus neoformans	34.59	1.00e-140	493.00
IUUC-Cme-027173	Cyanidioschyzon merolae	32.03	5.00e-79	289.00
IUUC-Dre-027733	Danio rerio	64.81	0.00e+00	1196.00
IUUC-Dno-029439	Dasypus novemcinctus	88.84	0.00e+00	1590.00
IUUC-Dor-030329	Dipodomys ordii	77.42	0.00e+00	1336.00
IUUC-Dse-031511	Dothistroma septosporum	29.89	8.00e-105	375.00
IUUC-Dme-031694	Drosophila melanogaster	40.20	0.00e+00	679.00
IUUC-Ete-032930	Echinops telfairi	82.19	0.00e+00	1310.00
IUUC-Eca-033302	Equus caballus	89.42	0.00e+00	1607.00
IUUC-Eeu-034516	Erinaceus europaeus	87.40	0.00e+00	1631.00
IUUC-Fca-036064	Felis catus	87.95	0.00e+00	1580.00
IUUC-Fal-037024	Ficedula albicollis	70.66	0.00e+00	1277.00
IUUC-Fox-037787	Fusarium oxysporum	29.25	1.00e-95	344.00
IUUC-Fso-038378	Fusarium solani	29.39	2.00e-96	347.00
IUUC-Gmo-039637	Gadus morhua	53.52	3.00e-154	538.00
IUUC-Ggr-040108	Gaeumannomyces graminis	29.98	2.00e-105	377.00
IUUC-Gga-040982	Gallus gallus	71.62	0.00e+00	1300.00
IUUC-Gac-041565	Gasterosteus aculeatus	56.98	0.00e+00	957.00
IUUC-Gma-043414	Glycine max	36.07	4.00e-155	542.00
IUUC-Ggo-045463	Gorilla gorilla	88.78	0.00e+00	1625.00
IUUC-Hsa-045675	Homo sapiens	88.75	0.00e+00	1626.00
IUUC-Hvu-047352	Hordeum vulgare	36.07	1.00e-137	483.00
IUUC-Itr-048088	Ictidomys tridecemlineatus	88.88	0.00e+00	1634.00
IUUC-Kpa-049164	Komagataella pastoris	32.98	2.00e-108	387.00
IUUC-Lch-050476	Latimeria chalumnae	68.80	0.00e+00	1261.00
IUUC-Lpe-051556	Leersia perrieri	33.80	1.00e-91	331.00
IUUC-Loc-052820	Lepisosteus oculatus	67.56	0.00e+00	1228.00
IUUC-Lma-052961	Leptosphaeria maculans	32.68	5.00e-109	389.00
IUUC-Laf-054006	Loxodonta africana	86.39	0.00e+00	1561.00
IUUC-Mcc-055037	Macaca mulatta	88.75	0.00e+00	1626.00
IUUC-Mor-057280	Magnaporthe oryzae	29.51	5.00e-107	382.00
IUUC-Mpo-057408	Magnaporthe poae	29.05	4.00e-101	363.00
IUUC-Mtr-058473	Medicago truncatula	35.13	3.00e-151	529.00
IUUC-Mla-058892	Melampsora laricipopulina	34.45	3.00e-115	409.00
IUUC-Mga-059598	Meleagris gallopavo	60.84	0.00e+00	1015.00
IUUC-Mvi-060334	Microbotryum violaceum	34.83	4.00e-119	422.00
IUUC-Mmr-061239	Microcebus murinus	87.75	0.00e+00	1577.00
IUUC-Mdo-062471	Monodelphis domestica	78.99	0.00e+00	1383.00
IUUC-Mac-064631	Musa acuminata	35.87	7.00e-137	481.00
IUUC-Mpu-066039	Mustela putorius furo	89.29	0.00e+00	1637.00
IUUC-Mlu-067485	Myotis lucifugus	87.89	0.00e+00	1607.00
IUUC-Nfi-068319	Neosartorya fischeri	30.32	9.00e-103	368.00
IUUC-Ncr-068725	Neurospora crassa	30.24	3.00e-103	370.00
IUUC-Nle-069050	Nomascus leucogenys	88.75	0.00e+00	1628.00
IUUC-Opr-070437	Ochotona princeps	78.04	1.00e-136	480.00
IUUC-Ont-071574	Oreochromis niloticus	58.61	0.00e+00	1034.00
IUUC-Oan-072826	Ornithorhynchus anatinus	74.92	0.00e+00	1334.00
IUUC-Ocu-073995	Oryctolagus cuniculus	88.73	0.00e+00	1559.00
IUUC-Oba-075407	Oryza barthii	33.08	2.00e-124	440.00
IUUC-Obr-076451	Oryza brachyantha	36.11	1.00e-156	547.00
IUUC-Ogl-077535	Oryza glaberrima	35.93	4.00e-152	532.00
IUUC-Ogu-077995	Oryza glumaepatula	32.44	6.00e-120	425.00
IUUC-Oin-079431	Oryza indica	36.24	2.00e-154	539.00
IUUC-Olo-080495	Oryza longistaminata	32.54	8.00e-119	421.00
IUUC-Oni-082336	Oryza nivara	34.79	4.00e-142	498.00
IUUC-Opu-084028	Oryza punctata	34.35	6.00e-128	451.00
IUUC-Oru-084500	Oryza rufipogon	32.47	5.00e-120	425.00
IUUC-Osa-086242	Oryza sativa	36.13	4.00e-154	538.00
IUUC-Ola-086612	Oryzias latipes	56.15	0.00e+00	817.00
IUUC-Olu-087703	Ostreococcus lucimarinus	30.61	6.00e-107	382.00
IUUC-Oga-088572	Otolemur garnettii	87.65	0.00e+00	1578.00
IUUC-Oar-090363	Ovis aries	88.62	0.00e+00	1622.00
IUUC-Ptr-090477	Pan troglodytes	88.42	0.00e+00	1610.00
IUUC-Pan-092914	Papio anubis	88.95	0.00e+00	1629.00
IUUC-Psi-093019	Pelodiscus sinensis	71.99	0.00e+00	1298.00
IUUC-Pma-094303	Petromyzon marinus	50.77	0.00e+00	795.00
IUUC-Pno-094938	Phaeosphaeria nodorum	32.55	6.00e-99	355.00
IUUC-Ppa-095720	Physcomitrella patens	34.38	4.00e-151	528.00
IUUC-Pfo-097034	Poecilia formosa	56.95	0.00e+00	983.00
IUUC-Pab-097669	Pongo abelii	88.84	0.00e+00	1625.00
IUUC-Pop-098835	Populus trichocarpa	36.74	5.00e-153	535.00
IUUC-Pca-101097	Procavia capensis	85.01	6.00e-176	611.00
IUUC-Ppe-101430	Prunus persica	36.32	3.00e-157	549.00
IUUC-Pva-103152	Pteropus vampyrus	88.86	0.00e+00	1630.00
IUUC-Pgr-103517	Puccinia graminis	31.58	1.00e-123	437.00
IUUC-Ptt-103697	Puccinia triticina	32.33	3.00e-101	363.00
IUUC-Pte-104121	Pyrenophora teres	31.25	5.00e-107	382.00
IUUC-Pyt-104672	Pyrenophora triticirepentis	31.55	4.00e-109	389.00
IUUC-Rno-105435	Rattus norvegicus	94.99	0.00e+00	1706.00
IUUC-Sce-106202	Saccharomyces cerevisiae	31.45	6.00e-111	395.00
IUUC-Sha-107272	Sarcophilus harrisii	78.93	0.00e+00	1330.00
IUUC-Sja-107744	Schizosaccharomyces japonicus	35.80	3.00e-150	526.00
IUUC-Spo-108256	Schizosaccharomyces pombe	37.21	6.00e-152	531.00
IUUC-Ssl-108618	Sclerotinia sclerotiorum	30.49	3.00e-113	403.00
IUUC-Smo-108762	Selaginella moellendorffii	36.72	3.00e-157	549.00
IUUC-Sit-110051	Setaria italica	36.33	6.00e-153	535.00
IUUC-Sly-111181	Solanum lycopersicum	35.15	1.00e-152	533.00
IUUC-Stu-112018	Solanum tuberosum	35.21	4.00e-152	532.00
IUUC-Sar-113348	Sorex araneus	86.35	0.00e+00	1122.00
IUUC-Sbi-114282	Sorghum bicolor	36.42	1.00e-153	537.00
IUUC-Sre-114946	Sporisorium reilianum	31.69	5.00e-94	339.00
IUUC-Ssc-115287	Sus scrofa	88.29	0.00e+00	1610.00
IUUC-Tgu-117138	Taeniopygia guttata	67.78	0.00e+00	1076.00
IUUC-Tru-118232	Takifugu rubripes	57.91	0.00e+00	999.00
IUUC-Tsy-119502	Tarsius syrichta	74.44	0.00e+00	1297.00
IUUC-Tni-120378	Tetraodon nigroviridis	57.70	0.00e+00	982.00
IUUC-Tca-121506	Theobroma cacao	35.01	3.00e-146	512.00
IUUC-Tre-122166	Trichoderma reesei	30.08	1.00e-105	378.00
IUUC-Tvi-122385	Trichoderma virens	30.07	2.00e-107	383.00
IUUC-Tae-122836	Triticum aestivum	36.08	4.00e-157	548.00
IUUC-Tur-126490	Triticum urartu	32.45	2.00e-114	406.00
IUUC-Tme-127157	Tuber melanosporum	33.37	6.00e-111	395.00
IUUC-Tbe-127981	Tupaia belangeri	80.65	0.00e+00	1358.00
IUUC-Ttr-128886	Tursiops truncatus	86.83	0.00e+00	1572.00
IUUC-Uma-129439	Ustilago maydis	31.91	2.00e-101	364.00
IUUC-Vda-129760	Verticillium dahliae	30.02	2.00e-104	374.00
IUUC-Vpa-130456	Vicugna pacos	87.75	0.00e+00	1597.00
IUUC-Vvi-131086	Vitis vinifera	35.56	1.00e-151	530.00
IUUC-Xtr-131829	Xenopus tropicalis	67.11	0.00e+00	1229.00
IUUC-Xma-133588	Xiphophorus maculatus	57.51	0.00e+00	970.00
IUUC-Yli-134328	Yarrowia lipolytica	31.05	7.00e-112	398.00
IUUC-Zma-135808	Zea mays	36.26	2.00e-152	533.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence