iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mcc-055450

UUCD1 version

UUC-MaM-00356

Ensembl Protein ID

ENSMMUP00000012435.2

UniProt Accession

F6YMW6; F6YMW6_MACMU

Genbank Protein ID

AFE77750.1; AFH31985.1

Protein Name

TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L isoform a

Genbank Nucleotide ID

JSUE03003554; JU475181

Gene Name

TAF5L

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000009508.3	ENSMMUT00000013268.3	ENSMMUP00000012435.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.30e-41	139.1	508	540
UBD/Beta-Prp	6.40e-67	226.9	271	569

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlr 31
           gHtd +t+l f +d +l++s+s D++++vWD+r
   Q: 508  GHTDNITSLTFsPDsGLIASASMDNSVRVWDIR 540
           8***********999****************75 PP

UBD/Beta-Prp

   S: 13   itcvkfspdksllatgsrdgtikvwdvttgkl................................lrslsgheaevtavkfspdgkilvt 69
           ++   +spd++lla+g+++++ik+w+++++kl                                ++ l gh ++v++++f  d++ l++
   Q: 271  LNTAEISPDSKLLAAGFDNSCIKLWSLRSKKLksephqvdvsrihlacdileeeddeddnagteMKILRGHCGPVYSTRFLADSSGLLS 359
           5667889********************************************************************************** PP
   S: 70   gseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslD 158
           +seD+ i+ wdl +++ ++ ++gh + v++l++sp++ +++sGshdrt+r+w  +  + l+ + +gh + v cv++hp++n+l++Gs+D
   Q: 360  CSEDMSIRYWDLGSFTNTVLYQGHAYPVWDLDISPYSLYFASGSHDRTARLWSFDRTYPLR-IYAGHLADVDCVKFHPNSNYLATGSTD 447
           *************************************************************.*************************** PP
   S: 159  rtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsir 247
           +tvrlW+ ++g+ +r +tg h ++v sl+f++ngk+l+s+++d+++klwdl +g+  ++l+ghtdn++s+ fsp++ +++s+s+D+s+r
   Q: 448  KTVRLWSAQQGNSVRLFTG-HRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASGTLYKELRGHTDNITSLTFSPDSGLIASASMDNSVR 535
           ******************9.********************************************************************* PP
   S: 248  iW...........dlrsgdllktlqlhnssvisv 270
           +W           d  s++l+++++++ s+v sv
   Q: 536  VWdirntygsapaDGSSSELVGVYTGQMSNVLSV 569
           **44444444444444444444444444555555 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MKRVRTEQIQ MAVSCYLKRR QYVDSDGPLK QGLRLSQTAE EMAANLTVQS ESGCANIVSA 60
APCQAEPQQY EVQFGRLRNF LTDSDSQHSH EVMPLLYPLF VYLHLNLVQN SPKSTVESFY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAAACGAG TGCGTACCGA GCAGATTCAG ATGGCAGTGT CCTGCTACCT CAAACGCCGG 60
CAGTACGTGG ACTCAGACGG CCCCCTGAAG CAAGGACTGC GGCTGTCACA GACTGCTGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR027295--Quinoprotein_ADH-like_fam
IPR007582--TFIID_NTD2
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04494--TFIID_NTD2
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0016607--C:nuclear speck
GO:0000932--C:P-body
GO:0030914--C:STAGA complex
GO:0033276--C:transcription factor TFTC complex
GO:0004402--F:histone acetyltransferase activity
GO:0003713--F:transcription coactivator activity
GO:0043966--P:histone H3 acetylation

KEGG

mcc:693770

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002016	Ailuropoda melanoleuca	98.30	0.00e+00	1111.00
IUUC-Apl-003636	Anas platyrhynchos	92.55	0.00e+00	1129.00
IUUC-Aca-004229	Anolis carolinensis	91.68	0.00e+00	1098.00
IUUC-Ame-010599	Astyanax mexicanus	66.89	0.00e+00	823.00
IUUC-Bta-013404	Bos taurus	93.04	0.00e+00	1053.00
IUUC-Cja-019643	Callithrix jacchus	99.66	0.00e+00	1147.00
IUUC-Cfa-020913	Canis familiaris	98.81	0.00e+00	1135.00
IUUC-Cpo-021777	Cavia porcellus	95.08	0.00e+00	1083.00
IUUC-Csa-024184	Chlorocebus sabaeus	99.66	0.00e+00	1149.00
IUUC-Cho-024638	Choloepus hoffmanni	97.96	0.00e+00	1103.00
IUUC-Cin-025618	Ciona intestinalis	35.13	2.00e-91	329.00
IUUC-Csv-025874	Ciona savignyi	33.96	2.00e-90	327.00
IUUC-Dre-028817	Danio rerio	67.11	0.00e+00	816.00
IUUC-Dno-029969	Dasypus novemcinctus	88.79	0.00e+00	1055.00
IUUC-Dor-031117	Dipodomys ordii	95.93	0.00e+00	1119.00
IUUC-Ete-032712	Echinops telfairi	89.64	0.00e+00	991.00
IUUC-Eca-033742	Equus caballus	98.81	0.00e+00	1135.00
IUUC-Eeu-035096	Erinaceus europaeus	95.76	0.00e+00	1132.00
IUUC-Fca-035769	Felis catus	97.80	0.00e+00	1151.00
IUUC-Fal-036645	Ficedula albicollis	92.09	0.00e+00	1064.00
IUUC-Gmo-038636	Gadus morhua	64.00	0.00e+00	778.00
IUUC-Gga-040144	Gallus gallus	92.36	0.00e+00	1099.00
IUUC-Gac-041716	Gasterosteus aculeatus	68.23	0.00e+00	819.00
IUUC-Ggo-044568	Gorilla gorilla	99.83	0.00e+00	1148.00
IUUC-Hsa-046178	Homo sapiens	99.83	0.00e+00	1148.00
IUUC-Itr-048967	Ictidomys tridecemlineatus	90.66	0.00e+00	1100.00
IUUC-Lch-050501	Latimeria chalumnae	78.01	0.00e+00	874.00
IUUC-Loc-052895	Lepisosteus oculatus	82.21	0.00e+00	643.00
IUUC-Laf-053950	Loxodonta africana	93.55	0.00e+00	1076.00
IUUC-Meu-056182	Macropus eugenii	89.30	0.00e+00	1024.00
IUUC-Mga-059619	Meleagris gallopavo	92.53	0.00e+00	1102.00
IUUC-Mmr-061074	Microcebus murinus	97.63	0.00e+00	1150.00
IUUC-Mdo-062307	Monodelphis domestica	94.38	0.00e+00	904.00
IUUC-Mmu-063226	Mus musculus	93.21	0.00e+00	1071.00
IUUC-Mpu-066016	Mustela putorius furo	98.13	0.00e+00	1107.00
IUUC-Mlu-067257	Myotis lucifugus	88.15	0.00e+00	1082.00
IUUC-Nle-070139	Nomascus leucogenys	99.66	0.00e+00	1146.00
IUUC-Opr-070243	Ochotona princeps	93.04	0.00e+00	1089.00
IUUC-Ont-072686	Oreochromis niloticus	69.17	0.00e+00	839.00
IUUC-Oan-073670	Ornithorhynchus anatinus	82.49	0.00e+00	841.00
IUUC-Ocu-074525	Oryctolagus cuniculus	98.47	0.00e+00	1145.00
IUUC-Ola-086524	Oryzias latipes	68.50	0.00e+00	856.00
IUUC-Oga-088540	Otolemur garnettii	98.13	0.00e+00	1129.00
IUUC-Oar-089793	Ovis aries	89.98	0.00e+00	987.00
IUUC-Ptr-091154	Pan troglodytes	99.83	0.00e+00	1148.00
IUUC-Pan-092759	Papio anubis	100.00	0.00e+00	1152.00
IUUC-Psi-094008	Pelodiscus sinensis	89.64	0.00e+00	1093.00
IUUC-Pma-094593	Petromyzon marinus	46.23	6.00e-134	471.00
IUUC-Pfo-097409	Poecilia formosa	67.55	0.00e+00	815.00
IUUC-Pab-097946	Pongo abelii	87.61	0.00e+00	989.00
IUUC-Pca-100727	Procavia capensis	90.15	0.00e+00	1000.00
IUUC-Pva-103211	Pteropus vampyrus	84.38	0.00e+00	1011.00
IUUC-Ptt-103995	Puccinia triticina	43.83	3.00e-70	260.00
IUUC-Rno-105236	Rattus norvegicus	93.38	0.00e+00	1056.00
IUUC-Sha-106833	Sarcophilus harrisii	94.09	0.00e+00	1097.00
IUUC-Sar-113381	Sorex araneus	98.64	0.00e+00	1162.00
IUUC-Ssc-116421	Sus scrofa	95.08	0.00e+00	1136.00
IUUC-Tgu-117143	Taeniopygia guttata	93.04	0.00e+00	1134.00
IUUC-Tru-118680	Takifugu rubripes	68.17	0.00e+00	840.00
IUUC-Tsy-119622	Tarsius syrichta	82.85	0.00e+00	863.00
IUUC-Tni-120131	Tetraodon nigroviridis	67.67	0.00e+00	843.00
IUUC-Tbe-127656	Tupaia belangeri	95.45	3.00e-89	322.00
IUUC-Ttr-129171	Tursiops truncatus	94.57	0.00e+00	1075.00
IUUC-Xtr-132241	Xenopus tropicalis	81.19	0.00e+00	964.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence