iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ocu-074161

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAGW02028941

Gene Name

RNF146

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000006545.3	ENSOCUT00000006544.3	ENSOCUP00000005656.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	93.61	8.00e-163	570.00	IUUC-Hsa-045790

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MMAGCGEIDH SINMLPTNKK ANESCSNTAP SLTVPECAIC LQTCVHPVSL PCKHVFCYLC 60
VKGASWLGKR CALCRQEIPE DFLDKPTLLS PEELKAASRG NGEYAWYYEG RNGWWQYDER 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTAAGTGA ACATGGTTTT TCCAAAGCTA TGGTAAATTA AATGGGTTGG TATAAAGGGA 60
TCACATAAAC AAAACTAGTG TCTGCTAATA CTAACTGATA GAATTAAAAA GGAGAGAATG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR033509--RNF146
IPR004170--WWE-dom
IPR018123--WWE-dom_subgr
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50918--WWE
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF02825--WWE

SMART

SM00184--RING
SM00678--WWE

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0005886--C:plasma membrane
GO:0072572--F:poly-ADP-D-ribose binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0090263--P:positive regulation of canonical Wnt signaling pathway
GO:0051865--P:protein autoubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0016055--P:Wnt signaling pathway

KEGG

ocu:100339240

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002237	Ailuropoda melanoleuca	90.53	6.00e-149	520.00
IUUC-Apl-004143	Anas platyrhynchos	79.26	5.00e-131	460.00
IUUC-Aca-004557	Anolis carolinensis	77.34	3.00e-128	451.00
IUUC-Ame-011088	Astyanax mexicanus	62.69	2.00e-83	302.00
IUUC-Bta-012639	Bos taurus	93.43	1.00e-150	525.00
IUUC-Cel-018462	Caenorhabditis elegans	28.35	6.00e-19	87.00
IUUC-Cja-019397	Callithrix jacchus	92.50	1.00e-153	535.00
IUUC-Cfa-021140	Canis familiaris	89.72	1.00e-156	545.00
IUUC-Cpo-021387	Cavia porcellus	89.55	1.00e-165	575.00
IUUC-Csa-023503	Chlorocebus sabaeus	91.02	3.00e-150	524.00
IUUC-Cho-024895	Choloepus hoffmanni	88.49	1.00e-133	469.00
IUUC-Cin-025455	Ciona intestinalis	52.63	8.00e-43	166.00
IUUC-Dre-028824	Danio rerio	47.27	2.00e-82	298.00
IUUC-Dno-029269	Dasypus novemcinctus	89.69	8.00e-154	536.00
IUUC-Dor-030592	Dipodomys ordii	90.50	1.00e-163	568.00
IUUC-Dme-031618	Drosophila melanogaster	57.33	1.00e-55	210.00
IUUC-Ete-032478	Echinops telfairi	90.96	6.00e-160	556.00
IUUC-Eca-033389	Equus caballus	94.07	3.00e-174	603.00
IUUC-Fca-035488	Felis catus	91.29	3.00e-155	540.00
IUUC-Fal-037087	Ficedula albicollis	79.26	3.00e-151	527.00
IUUC-Gga-040401	Gallus gallus	86.08	2.00e-135	475.00
IUUC-Gac-042412	Gasterosteus aculeatus	65.66	3.00e-88	318.00
IUUC-Ggo-045417	Gorilla gorilla	95.36	2.00e-150	525.00
IUUC-Hsa-045790	Homo sapiens	92.22	4.00e-153	533.00
IUUC-Itr-048820	Ictidomys tridecemlineatus	93.50	1.00e-165	575.00
IUUC-Lch-049493	Latimeria chalumnae	71.71	3.00e-116	411.00
IUUC-Loc-052927	Lepisosteus oculatus	67.48	2.00e-103	369.00
IUUC-Laf-053904	Loxodonta africana	88.89	1.00e-154	538.00
IUUC-Mcc-055427	Macaca mulatta	87.81	1.00e-153	535.00
IUUC-Mmr-060580	Microcebus murinus	92.16	3.00e-152	530.00
IUUC-Mdo-062094	Monodelphis domestica	97.73	7.00e-79	285.00
IUUC-Mmu-063363	Mus musculus	91.32	4.00e-161	560.00
IUUC-Mpu-066816	Mustela putorius furo	91.06	1.00e-147	515.00
IUUC-Mlu-067433	Myotis lucifugus	90.81	6.00e-170	589.00
IUUC-Nle-068986	Nomascus leucogenys	91.67	3.00e-166	577.00
IUUC-Ont-072670	Oreochromis niloticus	59.64	9.00e-82	296.00
IUUC-Oan-073330	Ornithorhynchus anatinus	86.57	9.00e-107	379.00
IUUC-Oga-089159	Otolemur garnettii	92.96	2.00e-175	607.00
IUUC-Oar-089586	Ovis aries	91.83	1.00e-140	492.00
IUUC-Ptr-090987	Pan troglodytes	92.22	4.00e-153	533.00
IUUC-Pan-091867	Papio anubis	87.78	1.00e-152	532.00
IUUC-Psi-094024	Pelodiscus sinensis	84.66	2.00e-138	484.00
IUUC-Pma-094453	Petromyzon marinus	63.91	4.00e-65	241.00
IUUC-Pfo-097108	Poecilia formosa	53.46	1.00e-85	309.00
IUUC-Pab-097997	Pongo abelii	92.72	3.00e-159	553.00
IUUC-Pca-100260	Procavia capensis	89.83	4.00e-156	543.00
IUUC-Pva-103140	Pteropus vampyrus	90.56	2.00e-159	554.00
IUUC-Rno-105795	Rattus norvegicus	90.65	2.00e-162	564.00
IUUC-Sha-107033	Sarcophilus harrisii	88.92	8.00e-155	539.00
IUUC-Ssc-116395	Sus scrofa	91.92	5.00e-173	600.00
IUUC-Tgu-116685	Taeniopygia guttata	77.43	1.00e-132	466.00
IUUC-Tru-118014	Takifugu rubripes	74.88	2.00e-83	301.00
IUUC-Tsy-119326	Tarsius syrichta	87.71	3.00e-171	594.00
IUUC-Tni-120322	Tetraodon nigroviridis	69.95	1.00e-81	296.00
IUUC-Tbe-128067	Tupaia belangeri	91.94	4.00e-161	560.00
IUUC-Ttr-128530	Tursiops truncatus	91.11	1.00e-157	549.00
IUUC-Vpa-130322	Vicugna pacos	93.33	2.00e-162	565.00
IUUC-Xtr-132606	Xenopus tropicalis	67.05	2.00e-116	411.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence