iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMUSG00000041506.15	ENSMUST00000047721.9	ENSMUSP00000038580.8
ENSMUSG00000041506.15	ENSMUST00000185336.1	ENSMUSP00000140949.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	GXD
DNA & RNA Element
AREsite	microRNA	TRANSFAC	RepTar
miRNAMap	RAID2
Protein-protein Interaction
IID	iRefIndex	PINA	HINT
Mentha
Post-translational Modifications (PTMs)
dbPAF	PhosphositePlus	dbPTM	Phospho.ELM
UniProt	PHOSIDA
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.20e-29	102.1	322	356
UBD/Beta-Prp	9.90e-42	144.2	145	406

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sdtllvsGsdDgtikvWDlrtgv 34
           gH++s+ c+++ ++ ++vsG+dDg++ +W l++ +
   Q: 322  GHQGSIDCIHLiNEEHMVSGADDGSVALWGLSKKR 356
           8*********9999***************987665 PP

UBD/Beta-Prp

   S: 9    hksvitcvkfspdksllatgsrdgtikvwdvttgkl...........lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkc 86
           h+  itc+ ++pd+  ++++ +d ti+ w+v+tg +             +  gh++ v ++ +s+dgk+l++g + ++i +w+ ++++ 
   Q: 145  HQLSITCLVITPDDLAIFSAAKDCTIIKWSVETGRKlhviprakkgaQGQPAGHSSHVLCMAISSDGKYLASGDRSKLILIWEAQSCQH 233
           66789999999***********************99999999999988889999999******************************** PP
   S: 87   vhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl 175
           ++t++gh d v  l+f + ++ l s+shdr ++vw+  +++ +e tl gh+++v  +   + ++++ +G+ D+tvr+W+++ ++ l   
   Q: 234  LYTFTGHRDAVSGLAFRKGTHQLYSTSHDRSVKVWNAAENSYVE-TLFGHQDAVAALDALSRECCVTAGGRDGTVRVWKIPEESQLVFY 321
           ******************99***********************9.***********************************999988755 PP
   S: 176  tgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnght...........dnvksvrfspnderlvsgssDgsiriWdlr 252
            g h++s+ ++ +  + +++vsg++dg+v lw l++++ +  +++              +v+sv+++ n++++++gs+   +r+W + 
   Q: 322  -G-HQGSIDCIHLINE-EHMVSGADDGSVALWGLSKKRPLALQREAHglhgepgleqpFWVSSVAALLNTDLVATGSHNARVRLWQCG 406
           .6.*********8886.7*****************999977777655588999999999**************************875 PP

Organism

Mus musculus

Functional Description
(View)

Component of a nucleolar small nuclear ribonucleoprotein particle (snoRNP) thought to participate in the processing and modification of pre-ribosomal RNA.

Protein Sequence
(Fasta)

MSTAVATRKR AKPAPGPGAA PVAGKRRRKV DSAADRGKSK GGGKMNEEIS SDSESESLAP 60
RKTEEEEEEE LEETAQEKKL RLAKLYLEQL RQQEEEKAEA RAFEEDQVAG RLKEDVLEQR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTTTTGGAGC CATGGTTCTC CTGGGGCAAG AGGTAGGGAG CGTTCAGATT TGCCCTTTAG 60
GAGGCTGGCC TCCTACTCCT TGGTTTACAT ATCCCCATCT CCAAACCTGC ACTTTGTACC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0488--Methylation
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0687--Ribonucleoprotein
KW-0694--RNA-binding
KW-0698--rRNA processing
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0031428--C:box C/D snoRNP complex
GO:0005730--C:nucleolus
GO:0032040--C:small-subunit processome
GO:0003723--F:RNA binding
GO:0030515--F:snoRNA binding
GO:0034511--F:U3 snoRNA binding
GO:0006364--P:rRNA processing

KEGG

mmu:27966

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000586	Aegilops tauschii	34.29	3.00e-57	216.00
IUUC-Aml-002072	Ailuropoda melanoleuca	92.13	0.00e+00	749.00
IUUC-Atr-002824	Amborella trichopoda	37.76	4.00e-72	265.00
IUUC-Apl-003264	Anas platyrhynchos	75.34	1.00e-167	582.00
IUUC-Aca-004898	Anolis carolinensis	72.41	0.00e+00	637.00
IUUC-Aly-005535	Arabidopsis lyrata	37.96	7.00e-66	244.00
IUUC-Ath-007119	Arabidopsis thaliana	36.39	1.00e-71	264.00
IUUC-Ago-007710	Ashbya gossypii	28.34	2.00e-57	216.00
IUUC-Acl-008345	Aspergillus clavatus	32.93	8.00e-57	214.00
IUUC-Afl-008718	Aspergillus flavus	32.27	4.00e-55	209.00
IUUC-Afu-008966	Aspergillus fumigatus	29.37	2.00e-54	207.00
IUUC-Ani-009214	Aspergillus nidulans	31.60	2.00e-57	216.00
IUUC-Ang-009774	Aspergillus niger	32.84	3.00e-58	219.00
IUUC-Aor-009956	Aspergillus oryzae	32.27	4.00e-55	209.00
IUUC-Ate-010449	Aspergillus terreus	29.87	2.00e-55	210.00
IUUC-Ame-011860	Astyanax mexicanus	70.23	1.00e-167	582.00
IUUC-Bgr-012213	Blumeria graminis	30.67	2.00e-62	233.00
IUUC-Bta-012698	Bos taurus	90.95	0.00e+00	739.00
IUUC-Bci-013973	Botrytis cinerea	27.85	5.00e-59	222.00
IUUC-Bdi-014790	Brachypodium distachyon	36.65	8.00e-64	238.00
IUUC-Bol-016068	Brassica oleracea	37.83	9.00e-67	247.00
IUUC-Bra-017410	Brassica rapa	35.98	3.00e-62	233.00
IUUC-Cel-018616	Caenorhabditis elegans	37.01	7.00e-74	271.00
IUUC-Cja-019532	Callithrix jacchus	89.68	0.00e+00	738.00
IUUC-Cfa-020961	Canis familiaris	88.89	0.00e+00	741.00
IUUC-Cpo-021527	Cavia porcellus	89.29	0.00e+00	747.00
IUUC-Csa-023106	Chlorocebus sabaeus	94.78	0.00e+00	761.00
IUUC-Cin-025670	Ciona intestinalis	52.17	2.00e-124	439.00
IUUC-Csv-026172	Ciona savignyi	51.92	4.00e-117	414.00
IUUC-Cgl-026619	Colletotrichum gloeosporioides	32.06	2.00e-62	233.00
IUUC-Cne-027070	Cryptococcus neoformans	30.13	2.00e-47	183.00
IUUC-Cme-027125	Cyanidioschyzon merolae	26.58	3.00e-32	133.00
IUUC-Dre-027919	Danio rerio	66.67	1.00e-157	549.00
IUUC-Dno-029684	Dasypus novemcinctus	94.65	6.00e-170	590.00
IUUC-Dor-030363	Dipodomys ordii	86.70	7.00e-106	377.00
IUUC-Dse-031503	Dothistroma septosporum	31.20	6.00e-59	221.00
IUUC-Dme-031979	Drosophila melanogaster	44.56	2.00e-97	349.00
IUUC-Eca-033735	Equus caballus	93.75	0.00e+00	725.00
IUUC-Fca-036193	Felis catus	92.17	0.00e+00	737.00
IUUC-Fal-037058	Ficedula albicollis	70.57	1.00e-168	586.00
IUUC-Fox-038036	Fusarium oxysporum	31.41	4.00e-62	232.00
IUUC-Fso-038298	Fusarium solani	32.46	1.00e-61	231.00
IUUC-Gmo-038796	Gadus morhua	64.99	8.00e-143	500.00
IUUC-Ggr-040074	Gaeumannomyces graminis	31.73	2.00e-51	197.00
IUUC-Gga-040743	Gallus gallus	79.26	1.00e-136	479.00
IUUC-Gac-042583	Gasterosteus aculeatus	64.07	7.00e-166	577.00
IUUC-Gma-042659	Glycine max	39.55	7.00e-81	294.00
IUUC-Ggo-045543	Gorilla gorilla	92.42	0.00e+00	760.00
IUUC-Hsa-047017	Homo sapiens	94.78	0.00e+00	761.00
IUUC-Hvu-047173	Hordeum vulgare	38.22	4.00e-70	258.00
IUUC-Itr-048062	Ictidomys tridecemlineatus	86.95	0.00e+00	752.00
IUUC-Kpa-049262	Komagataella pastoris	32.23	8.00e-58	218.00
IUUC-Lch-050566	Latimeria chalumnae	72.58	3.00e-157	548.00
IUUC-Lpe-051651	Leersia perrieri	36.58	2.00e-68	253.00
IUUC-Loc-051997	Lepisosteus oculatus	70.64	2.00e-165	575.00
IUUC-Lma-053182	Leptosphaeria maculans	29.90	8.00e-60	224.00
IUUC-Laf-054105	Loxodonta africana	93.40	0.00e+00	718.00
IUUC-Mcc-055215	Macaca mulatta	94.56	0.00e+00	761.00
IUUC-Meu-055943	Macropus eugenii	80.34	0.00e+00	651.00
IUUC-Mor-057069	Magnaporthe oryzae	32.40	2.00e-61	230.00
IUUC-Mpo-057358	Magnaporthe poae	30.25	6.00e-50	192.00
IUUC-Mtr-058209	Medicago truncatula	39.10	3.00e-80	292.00
IUUC-Mla-059043	Melampsora laricipopulina	26.60	4.00e-47	182.00
IUUC-Mga-060024	Meleagris gallopavo	74.77	1.00e-153	535.00
IUUC-Mvi-060371	Microbotryum violaceum	32.02	1.00e-67	251.00
IUUC-Mmr-061403	Microcebus murinus	94.62	0.00e+00	744.00
IUUC-Mdo-063026	Monodelphis domestica	77.45	0.00e+00	666.00
IUUC-Mac-064801	Musa acuminata	37.78	6.00e-77	281.00
IUUC-Mpu-065760	Mustela putorius furo	90.11	0.00e+00	755.00
IUUC-Mlu-067963	Myotis lucifugus	93.72	0.00e+00	737.00
IUUC-Nfi-068288	Neosartorya fischeri	31.45	3.00e-58	219.00
IUUC-Ncr-068679	Neurospora crassa	32.85	1.00e-55	211.00
IUUC-Nle-069766	Nomascus leucogenys	84.03	0.00e+00	678.00
IUUC-Opr-070906	Ochotona princeps	93.03	0.00e+00	757.00
IUUC-Ont-071661	Oreochromis niloticus	62.08	1.00e-167	582.00
IUUC-Oan-073465	Ornithorhynchus anatinus	65.70	3.00e-148	518.00
IUUC-Ocu-074263	Oryctolagus cuniculus	93.05	0.00e+00	747.00
IUUC-Oba-075607	Oryza barthii	38.44	2.00e-63	236.00
IUUC-Ogl-077387	Oryza glaberrima	37.83	4.00e-67	248.00
IUUC-Ogu-078323	Oryza glumaepatula	38.67	2.00e-67	249.00
IUUC-Oin-079977	Oryza indica	32.73	2.00e-45	176.00
IUUC-Olo-080857	Oryza longistaminata	38.54	2.00e-67	249.00
IUUC-Ome-081568	Oryza meridionalis	38.54	1.00e-66	247.00
IUUC-Oni-082685	Oryza nivara	38.67	1.00e-70	260.00
IUUC-Opu-084049	Oryza punctata	38.67	4.00e-67	248.00
IUUC-Oru-084348	Oryza rufipogon	38.67	1.00e-70	260.00
IUUC-Osa-086076	Oryza sativa	38.67	1.00e-70	260.00
IUUC-Ola-086991	Oryzias latipes	69.27	5.00e-163	567.00
IUUC-Olu-087891	Ostreococcus lucimarinus	36.01	3.00e-65	242.00
IUUC-Oga-088991	Otolemur garnettii	92.60	0.00e+00	758.00
IUUC-Oar-090430	Ovis aries	92.81	0.00e+00	726.00
IUUC-Ptr-091359	Pan troglodytes	95.01	0.00e+00	762.00
IUUC-Pan-092499	Papio anubis	94.33	0.00e+00	758.00
IUUC-Pma-094447	Petromyzon marinus	61.78	4.00e-130	457.00
IUUC-Pno-095008	Phaeosphaeria nodorum	30.20	1.00e-63	237.00
IUUC-Ppa-095680	Physcomitrella patens	40.00	8.00e-79	287.00
IUUC-Pfo-096430	Poecilia formosa	68.84	2.00e-164	572.00
IUUC-Pab-097649	Pongo abelii	94.78	0.00e+00	759.00
IUUC-Pop-100055	Populus trichocarpa	39.79	1.00e-77	284.00
IUUC-Pca-100317	Procavia capensis	73.84	2.00e-129	455.00
IUUC-Ppe-101999	Prunus persica	38.16	1.00e-80	293.00
IUUC-Pva-103046	Pteropus vampyrus	92.54	0.00e+00	740.00
IUUC-Pgr-103655	Puccinia graminis	29.51	1.00e-52	201.00
IUUC-Ptt-103812	Puccinia triticina	31.54	8.00e-47	181.00
IUUC-Pte-104243	Pyrenophora teres	29.92	2.00e-57	216.00
IUUC-Pyt-104512	Pyrenophora triticirepentis	30.10	4.00e-60	226.00
IUUC-Rno-104973	Rattus norvegicus	97.68	0.00e+00	792.00
IUUC-Sce-106329	Saccharomyces cerevisiae	25.45	2.00e-49	190.00
IUUC-Sha-106941	Sarcophilus harrisii	83.33	0.00e+00	664.00
IUUC-Sja-107821	Schizosaccharomyces japonicus	32.74	7.00e-64	238.00
IUUC-Spo-108329	Schizosaccharomyces pombe	36.34	9.00e-74	271.00
IUUC-Ssl-108552	Sclerotinia sclerotiorum	28.88	1.00e-59	224.00
IUUC-Smo-109198	Selaginella moellendorffii	38.69	3.00e-65	242.00
IUUC-Sit-109694	Setaria italica	37.68	4.00e-74	272.00
IUUC-Sly-111294	Solanum lycopersicum	38.64	3.00e-80	292.00
IUUC-Stu-112747	Solanum tuberosum	39.14	2.00e-81	296.00
IUUC-Sar-113315	Sorex araneus	72.65	2.00e-75	276.00
IUUC-Sbi-114694	Sorghum bicolor	36.88	9.00e-73	267.00
IUUC-Sre-114937	Sporisorium reilianum	28.70	7.00e-63	235.00
IUUC-Ssc-116127	Sus scrofa	94.00	0.00e+00	736.00
IUUC-Tgu-117242	Taeniopygia guttata	69.84	6.00e-107	380.00
IUUC-Tru-118285	Takifugu rubripes	62.87	2.00e-169	588.00
IUUC-Tni-120368	Tetraodon nigroviridis	62.24	7.00e-162	563.00
IUUC-Tca-121724	Theobroma cacao	37.37	2.00e-73	269.00
IUUC-Tre-122106	Trichoderma reesei	32.41	9.00e-66	244.00
IUUC-Tvi-122526	Trichoderma virens	32.01	4.00e-66	245.00
IUUC-Tae-122939	Triticum aestivum	37.70	8.00e-69	254.00
IUUC-Tur-126548	Triticum urartu	37.70	1.00e-68	254.00
IUUC-Tme-126985	Tuber melanosporum	34.63	4.00e-64	239.00
IUUC-Tbe-127923	Tupaia belangeri	94.47	0.00e+00	724.00
IUUC-Ttr-129308	Tursiops truncatus	88.38	0.00e+00	670.00
IUUC-Uma-129472	Ustilago maydis	30.41	1.00e-58	220.00
IUUC-Vda-129910	Verticillium dahliae	31.36	3.00e-64	239.00
IUUC-Vvi-131683	Vitis vinifera	39.68	3.00e-87	315.00
IUUC-Xtr-132118	Xenopus tropicalis	67.68	8.00e-159	553.00
IUUC-Xma-133804	Xiphophorus maculatus	68.34	1.00e-162	565.00
IUUC-Yli-134639	Yarrowia lipolytica	32.07	3.00e-60	226.00
IUUC-Zma-135884	Zea mays	37.53	2.00e-73	270.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence