iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	GXD
DNA & RNA Element
AREsite	microRNA	TRANSFAC	RepTar
RAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
dbPAF	PhosphositePlus	dbPTM
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.60e-07	31.0	639	673

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 3    tdsvtclaf..sd.tllvsGsdDgtikvWDlrtgv 34
           +++vtc++f      ll +G+  g++ vWDlr++ 
   Q: 639  ESKVTCCCFspLKaFLLFAGTVHGSVVVWDLREDS 673
           589******7622346999************9875 PP

Organism

Mus musculus

Functional Description
(View)

May play a role in ciliogenesis.

Protein Sequence
(Fasta)

MEPGKRRTKD DTWKADDLRK HLKVQSGSPK EEKKLREKKA HKDSESAAPE YREHKSRDPD 60
REARHKEKTA ERDLYTSTEH PRGERDRERH KERRKDAKDR EKDKLKERHR DQEAEKAHSR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTCGGCCCGT TGCTAGGAGG CGGGGACGCC GGCCCTCCTG GGACCCAAGT CGCAGCAGGC 60
CTGGCTGGCT GGTAGAGCTG AGCGACGGCG GGTTTATCTT CCTCCGGTGG CCCGCGCCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0966--Cell projection
KW-0969--Cilium
KW-0970--Cilium biogenesis/degradation
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0097546--C:ciliary base
GO:0005929--C:cilium
GO:0005868--C:cytoplasmic dynein complex
GO:0070062--C:extracellular exosome
GO:0005615--C:extracellular space
GO:0031021--C:interphase microtubule organizing center
GO:0000242--C:pericentriolar material
GO:0000922--C:spindle pole
GO:0060271--P:cilium assembly
GO:0048704--P:embryonic skeletal system morphogenesis

KEGG

mmu:217935

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001741	Ailuropoda melanoleuca	66.26	0.00e+00	1214.00
IUUC-Apl-003689	Anas platyrhynchos	58.26	0.00e+00	798.00
IUUC-Aca-004966	Anolis carolinensis	58.07	0.00e+00	752.00
IUUC-Ame-011562	Astyanax mexicanus	41.91	3.00e-74	273.00
IUUC-Bta-013100	Bos taurus	62.61	0.00e+00	1126.00
IUUC-Cja-019521	Callithrix jacchus	64.21	0.00e+00	1143.00
IUUC-Cfa-020943	Canis familiaris	63.87	0.00e+00	1102.00
IUUC-Cho-024500	Choloepus hoffmanni	73.17	0.00e+00	829.00
IUUC-Dre-028530	Danio rerio	46.96	2.00e-176	613.00
IUUC-Dno-029442	Dasypus novemcinctus	75.06	0.00e+00	1105.00
IUUC-Eca-033951	Equus caballus	78.81	0.00e+00	1104.00
IUUC-Fca-036542	Felis catus	65.18	0.00e+00	1115.00
IUUC-Fal-037079	Ficedula albicollis	56.60	0.00e+00	736.00
IUUC-Gac-041396	Gasterosteus aculeatus	47.17	2.00e-159	556.00
IUUC-Ggo-045638	Gorilla gorilla	77.49	0.00e+00	1046.00
IUUC-Hsa-046371	Homo sapiens	80.36	0.00e+00	1102.00
IUUC-Itr-049031	Ictidomys tridecemlineatus	77.16	0.00e+00	1031.00
IUUC-Lch-049862	Latimeria chalumnae	51.29	0.00e+00	695.00
IUUC-Loc-052637	Lepisosteus oculatus	49.10	1.00e-164	573.00
IUUC-Laf-053470	Loxodonta africana	70.47	0.00e+00	1232.00
IUUC-Mcc-055753	Macaca mulatta	79.91	0.00e+00	1130.00
IUUC-Mga-059230	Meleagris gallopavo	51.40	0.00e+00	718.00
IUUC-Mmr-061703	Microcebus murinus	69.22	0.00e+00	959.00
IUUC-Mpu-066650	Mustela putorius furo	66.80	0.00e+00	1071.00
IUUC-Nle-069413	Nomascus leucogenys	78.43	0.00e+00	1073.00
IUUC-Opr-071033	Ochotona princeps	74.93	0.00e+00	1055.00
IUUC-Ont-071388	Oreochromis niloticus	46.61	1.00e-169	590.00
IUUC-Oan-072714	Ornithorhynchus anatinus	49.68	0.00e+00	906.00
IUUC-Ocu-074557	Oryctolagus cuniculus	69.38	0.00e+00	1112.00
IUUC-Oga-088938	Otolemur garnettii	68.74	0.00e+00	1195.00
IUUC-Oar-090053	Ovis aries	60.16	0.00e+00	817.00
IUUC-Pan-091852	Papio anubis	80.76	0.00e+00	1033.00
IUUC-Psi-093781	Pelodiscus sinensis	59.94	0.00e+00	780.00
IUUC-Pfo-096078	Poecilia formosa	42.79	9.00e-147	514.00
IUUC-Pab-097947	Pongo abelii	80.21	0.00e+00	1102.00
IUUC-Rno-105970	Rattus norvegicus	93.61	0.00e+00	1600.00
IUUC-Tgu-117448	Taeniopygia guttata	56.02	0.00e+00	717.00
IUUC-Tni-120297	Tetraodon nigroviridis	44.84	2.00e-154	539.00
IUUC-Xtr-132946	Xenopus tropicalis	51.48	0.00e+00	647.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence