iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tgu-116655

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABQF01028890

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTGUG00000006699.1	ENSTGUT00000007008.1	ENSTGUP00000006939.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	6.70e-80	268.8	2639	3000

Active Site

Position(s)	Description	Evidence
2974	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 4    dlkkrlevefvgEegldl.gGvtreflallskelqnpdlglf.......lysendketlqpnpdsglknpehlklFeflGrllgkal 82
           d ++ ++++f+gEeg+++ +G++r+fl++++kelq+++l+l+       ++++++k+ l+p+p ++     +++lF+f+G+llg+a+
   Q: 2639 DPTYAFNIRFTGEEGHGTvSGSFRHFLWQVCKELQSSSLSLLllcpssaVNKNKGKYILTPSPITY----AEEQLFHFFGQLLGIAI 2721
           5667788********99658*********************9999999888888***********9....689************** PP
   S: 83   qdgrlldlplsksfyklllgkklsl.edleevdpelykslkeikena.esdieelgldltfs.vseei...............lget 151
           + + +l+l+l +sf+k+l+g++l+   dl+e d  +y+++k+ ++   e+++e+l+++++++     +                 + 
   Q: 2722 RADVPLPLDLLPSFWKTLVGEPLDPdVDLQEADILTYNYVKKFENISdETELEALCAEIASQhL-AMEspdcpnkpcckftylSLTG 2807
           *************************99************7777755436788888888888742.2224688999999999764555 PP
   S: 152  keeeLkpgGenipVtneNkeeYvklvveyrlke.gikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykg 237
           +e+eL+p+G++ipV +eNk+ Y  ++ ++r++e +  e+++a+r+G+ ++ipl+ll+ +t+ e+el +cG ++i++e lk++t+y+ 
   Q: 2808 EEVELCPRGRHIPVGWENKDVYAAAIRSLRMRElQTPECMTAVRAGLGSIIPLQLLTTLTPLEMELRTCGLPYINLEFLKAHTMYQV 2894
           6677*****************************99**************************************************** PP
   S: 238  gytedspaiqwFwevleefsseerkafLqFvTgssrlPl......gGfaelk....prlfvirk...dasddrlPssnTCfnyLkLP 311
           g++e++++i++Fw++le+f++ee ++f++F+++++r+P+      gG ++ +    p+++  ++    + d+r+++++TC++++kLP
   Q: 2895 GLMETDQHIEFFWSALEMFTQEELCKFIKFACNQERIPFtcpckdGGPDTAHvppyPMKIAPPDgaaGSPDSRYIRVETCMFMIKLP 2981
           *********************************************9999999998888888888*955555**************** PP
   S: 312  eYsskeilkekLlyAieet 330
           +Yss +i+ ekL+yAi+++
   Q: 2982 QYSSLDIMLEKLRYAIHYR 3000
           ****************986 PP

Organism

Taeniopygia guttata

Protein Sequence
(Fasta)

KMKELELLCS MKEVSFDGSD LENVVLALRE KFYQEVNSLI QKTSHPLAKT KTLVKSLMNR 60
AELLLHVTIA AQSGITRSIS GTPAETPACK SATETKVISH AVRQPVFLRS MSAPSDLEMI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAGATGAAGG AGCTGGAGCT TCTGTGTTCA ATGAAGGAAG TTTCTTTTGA TGGGAGTGAT 60
CTTGAGAACG TGGTCCTGGC ACTAAGGTCA GTATTAGTGA AGTTTTAGGC CTCAAAGGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002256	Ailuropoda melanoleuca	92.22	0.00e+00	5051.00
IUUC-Apl-004161	Anas platyrhynchos	97.48	0.00e+00	5418.00
IUUC-Aca-005341	Anolis carolinensis	93.22	0.00e+00	5175.00
IUUC-Ame-011574	Astyanax mexicanus	84.11	0.00e+00	3015.00
IUUC-Bta-012514	Bos taurus	89.94	0.00e+00	1781.00
IUUC-Cja-019148	Callithrix jacchus	91.21	0.00e+00	4996.00
IUUC-Cfa-020499	Canis familiaris	92.19	0.00e+00	5073.00
IUUC-Cpo-021894	Cavia porcellus	94.44	0.00e+00	2696.00
IUUC-Csa-023079	Chlorocebus sabaeus	92.45	0.00e+00	5064.00
IUUC-Cho-024415	Choloepus hoffmanni	91.03	0.00e+00	3193.00
IUUC-Dre-027452	Danio rerio	82.28	0.00e+00	3033.00
IUUC-Dno-029595	Dasypus novemcinctus	91.91	0.00e+00	5090.00
IUUC-Dor-030849	Dipodomys ordii	88.30	0.00e+00	1464.00
IUUC-Ete-032563	Echinops telfairi	84.62	0.00e+00	1536.00
IUUC-Eca-034202	Equus caballus	92.49	0.00e+00	5021.00
IUUC-Eeu-035175	Erinaceus europaeus	91.52	0.00e+00	999.00
IUUC-Fca-036295	Felis catus	92.22	0.00e+00	5104.00
IUUC-Fal-037003	Ficedula albicollis	98.99	0.00e+00	4645.00
IUUC-Gmo-038579	Gadus morhua	84.43	0.00e+00	2846.00
IUUC-Gga-040961	Gallus gallus	97.64	0.00e+00	5403.00
IUUC-Gac-041899	Gasterosteus aculeatus	84.61	0.00e+00	2894.00
IUUC-Ggo-045099	Gorilla gorilla	92.35	0.00e+00	5123.00
IUUC-Hsa-046331	Homo sapiens	92.35	0.00e+00	5098.00
IUUC-Itr-048190	Ictidomys tridecemlineatus	89.39	0.00e+00	1993.00
IUUC-Lch-049923	Latimeria chalumnae	91.10	0.00e+00	1154.00
IUUC-Loc-052630	Lepisosteus oculatus	84.79	0.00e+00	4068.00
IUUC-Laf-053394	Loxodonta africana	92.12	0.00e+00	5130.00
IUUC-Mcc-055763	Macaca mulatta	92.45	0.00e+00	5065.00
IUUC-Meu-056039	Macropus eugenii	87.86	0.00e+00	4807.00
IUUC-Mga-059500	Meleagris gallopavo	97.44	0.00e+00	5385.00
IUUC-Mmr-060868	Microcebus murinus	87.85	0.00e+00	4818.00
IUUC-Mdo-062772	Monodelphis domestica	92.99	0.00e+00	5143.00
IUUC-Mmu-063606	Mus musculus	92.48	0.00e+00	3549.00
IUUC-Mpu-065860	Mustela putorius furo	91.33	0.00e+00	4975.00
IUUC-Mlu-067376	Myotis lucifugus	93.56	0.00e+00	3341.00
IUUC-Nle-069693	Nomascus leucogenys	90.57	0.00e+00	4981.00
IUUC-Ont-072470	Oreochromis niloticus	84.94	0.00e+00	3064.00
IUUC-Oan-073693	Ornithorhynchus anatinus	91.97	0.00e+00	5177.00
IUUC-Ocu-074032	Oryctolagus cuniculus	91.26	0.00e+00	5037.00
IUUC-Ola-087433	Oryzias latipes	83.59	0.00e+00	1436.00
IUUC-Oga-088546	Otolemur garnettii	92.22	0.00e+00	5076.00
IUUC-Oar-089643	Ovis aries	86.03	0.00e+00	696.00
IUUC-Ptr-090504	Pan troglodytes	92.42	0.00e+00	5108.00
IUUC-Pan-092543	Papio anubis	92.36	0.00e+00	5056.00
IUUC-Psi-093952	Pelodiscus sinensis	92.16	0.00e+00	5165.00
IUUC-Pfo-096356	Poecilia formosa	81.35	0.00e+00	4678.00
IUUC-Pab-098240	Pongo abelii	92.39	0.00e+00	5054.00
IUUC-Pca-100994	Procavia capensis	95.92	0.00e+00	1648.00
IUUC-Pva-102263	Pteropus vampyrus	91.23	0.00e+00	4982.00
IUUC-Rno-104888	Rattus norvegicus	92.57	0.00e+00	3562.00
IUUC-Sha-106944	Sarcophilus harrisii	92.47	0.00e+00	5169.00
IUUC-Sar-113556	Sorex araneus	83.03	0.00e+00	902.00
IUUC-Ssc-116187	Sus scrofa	92.37	0.00e+00	4905.00
IUUC-Tru-118093	Takifugu rubripes	83.10	0.00e+00	3000.00
IUUC-Tni-119739	Tetraodon nigroviridis	83.39	0.00e+00	1462.00
IUUC-Tbe-127962	Tupaia belangeri	84.79	0.00e+00	1120.00
IUUC-Ttr-128819	Tursiops truncatus	86.82	0.00e+00	2663.00
IUUC-Vpa-130482	Vicugna pacos	94.17	0.00e+00	2578.00
IUUC-Xtr-132222	Xenopus tropicalis	88.53	0.00e+00	5064.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence