iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Csv-026014

UUCD1 version

UUC-CiS-00209

Ensembl Protein ID

ENSCSAVP00000008839.1

UniProt Accession

H2YU29; H2YU29_CIOSA

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCSAVG00000005245.1	ENSCSAVT00000008953.1	ENSCSAVP00000008839.1
ENSCSAVG00000005245.1	ENSCSAVT00000008954.1	ENSCSAVP00000008840.1
ENSCSAVG00000005245.1	ENSCSAVT00000008955.1	ENSCSAVP00000008841.1
ENSCSAVG00000005245.1	ENSCSAVT00000008956.1	ENSCSAVP00000008842.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.70e-51	169.9	236	265
UBD/Beta-Prp	2.50e-108	361.8	59	365

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sdtllvsGsdDgtikvWDlr 31
           H+++v+ l+  +d++ ++Gs+Dg +k+WD++
   Q: 236  HNGGVFTLHKsTDGY-ATGSRDGCVKLWDTS 265
           899999987667799.*************76 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatgs..rdgtikvwdvttgkllrsl.sgheaevtavkfspdgkilvtgseD..rtikvwdlstgkcvht 89
           gh+++ i+ ++ +p+++l+atg   +   i vw+++t+ +++ l  +h+ +v+++ fs++g+ l++++ D  +t  vw+ ++g ++ t
   Q: 59   GHNDDIIS-LALHPHEQLVATGQvgKEPYICVWNAKTMETVSILkDQHTHGVASLMFSHSGERLASVGLDgnNTFVVWEWRKGRMIAT 145
           78888888.9999********96115567***************889***********************999*************** PP
   S: 90   lkghedsvlslsfspsg.dklvsGshdrtirvwdletgqclee..tlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllr 173
            kgh+d+v ++s++p++ ++lv+ + ++ i+ w l  ++   +  ++ +  +  ++++v++ +  l  sG+l++ v +W  + ++l r
   Q: 146  AKGHTDRVFDISWDPTSeQRLVTCG-VKHIKFWALCGNSLTAKrgVFGKVADQQTVLCVSCADgHLTYSGTLNGDVYIW--RDNNLER 230
           ***************7747777776.*********999999889955555555555555555559999***********..8899999 PP
   S: 174  tltgghtdsvyslsfdsngkelvsgsldgtvklwdlq..........tgecvrtlnght............................. 222
             +++h++ v  l  + +g   ++gs+dg vklwd +                +  g++                             
   Q: 231  VVSSAHNGGVFTLHKSTDG--YATGSRDGCVKLWDTSfnplttinfkD-----SSYGYKgvsirsvcwssdriligtqnsevfeilvr 311
           99999*9999999999976..899***********9986655333220.....22222211122222222222222222222333333 PP
   S: 223  ..............dnvksvrfspnderlvsgssDgsiriWdlrsgdllktlql 262
                            + + ++p++ + +++s+D s+r+W l    ll++ +l
   Q: 312  drenptpltqghseGELWGLSVHPRKPIAATASDDCSVRLWSLVDHALLTCCNL 365
           333333333333345556666666666666666666666665555555555555 PP

Organism

Ciona savignyi

Protein Sequence
(Fasta)

MSDKTAPRSQ LRLEWVYGYR GHQCRNNLFY ISNDEIVYFV AGVGIVCNRR KQTQNFFLGH 60
NDDIISLALH PHEQLVATGQ VGKEPYICVW NAKTMETVSI LKDQHTHGVA SLMFSHSGER 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGCGACA AAACTGCACC AAGGTCGCAG CTGCGATTAG AATGGGTTTA TGGTTACAGG 60
TATGTGTATT GTGTAGTCTA TTAATATGGG GTACTGCTCA AAATCCGTGG TGTTTTATTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR005108--HELP
IPR027295--Quinoprotein_ADH-like_fam
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF03451--HELP
PF00400--WD40

SMART

SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001387	Ailuropoda melanoleuca	63.39	0.00e+00	2566.00
IUUC-Apl-003604	Anas platyrhynchos	63.08	0.00e+00	2524.00
IUUC-Aca-004572	Anolis carolinensis	61.45	0.00e+00	2457.00
IUUC-Ame-010713	Astyanax mexicanus	60.41	0.00e+00	2430.00
IUUC-Bta-012812	Bos taurus	63.59	0.00e+00	2566.00
IUUC-Cja-019191	Callithrix jacchus	63.03	0.00e+00	2531.00
IUUC-Cfa-020041	Canis familiaris	63.35	0.00e+00	2385.00
IUUC-Cpo-022304	Cavia porcellus	56.86	0.00e+00	2229.00
IUUC-Cre-022931	Chlamydomonas reinhardtii	34.27	4.00e-96	346.00
IUUC-Csa-023689	Chlorocebus sabaeus	62.57	0.00e+00	2467.00
IUUC-Cho-025038	Choloepus hoffmanni	64.29	0.00e+00	989.00
IUUC-Cin-025205	Ciona intestinalis	88.57	0.00e+00	3597.00
IUUC-Dre-028772	Danio rerio	58.13	0.00e+00	2402.00
IUUC-Dno-029982	Dasypus novemcinctus	62.45	0.00e+00	2448.00
IUUC-Dor-030980	Dipodomys ordii	55.35	0.00e+00	1031.00
IUUC-Ete-032554	Echinops telfairi	56.18	0.00e+00	632.00
IUUC-Eca-034161	Equus caballus	61.86	0.00e+00	2422.00
IUUC-Eeu-035180	Erinaceus europaeus	51.08	0.00e+00	913.00
IUUC-Fca-036307	Felis catus	63.39	0.00e+00	2564.00
IUUC-Fal-037332	Ficedula albicollis	62.72	0.00e+00	2485.00
IUUC-Gmo-039146	Gadus morhua	56.49	0.00e+00	2307.00
IUUC-Gga-041095	Gallus gallus	59.35	0.00e+00	1759.00
IUUC-Gac-042555	Gasterosteus aculeatus	60.27	0.00e+00	2413.00
IUUC-Ggo-045107	Gorilla gorilla	63.54	0.00e+00	2571.00
IUUC-Hsa-046482	Homo sapiens	63.59	0.00e+00	2574.00
IUUC-Itr-049023	Ictidomys tridecemlineatus	61.97	0.00e+00	2463.00
IUUC-Lch-050306	Latimeria chalumnae	57.94	0.00e+00	2160.00
IUUC-Loc-052642	Lepisosteus oculatus	63.57	0.00e+00	2534.00
IUUC-Laf-053649	Loxodonta africana	61.80	0.00e+00	2487.00
IUUC-Mcc-054733	Macaca mulatta	58.87	0.00e+00	2395.00
IUUC-Meu-056618	Macropus eugenii	52.14	0.00e+00	1194.00
IUUC-Mga-059202	Meleagris gallopavo	62.14	0.00e+00	2419.00
IUUC-Mmr-060729	Microcebus murinus	61.99	0.00e+00	2544.00
IUUC-Mdo-062462	Monodelphis domestica	63.12	0.00e+00	2481.00
IUUC-Mmu-063865	Mus musculus	63.03	0.00e+00	2569.00
IUUC-Mpu-066724	Mustela putorius furo	63.44	0.00e+00	2566.00
IUUC-Mlu-067816	Myotis lucifugus	63.12	0.00e+00	2555.00
IUUC-Nle-069911	Nomascus leucogenys	58.85	0.00e+00	2395.00
IUUC-Opr-070213	Ochotona princeps	60.17	0.00e+00	1330.00
IUUC-Ont-071928	Oreochromis niloticus	60.81	0.00e+00	2458.00
IUUC-Oan-073563	Ornithorhynchus anatinus	63.76	0.00e+00	2566.00
IUUC-Ocu-074531	Oryctolagus cuniculus	63.59	0.00e+00	2568.00
IUUC-Ola-086738	Oryzias latipes	58.18	0.00e+00	2399.00
IUUC-Olu-087860	Ostreococcus lucimarinus	38.28	1.00e-114	405.00
IUUC-Oga-088665	Otolemur garnettii	63.07	0.00e+00	2459.00
IUUC-Oar-090429	Ovis aries	63.65	0.00e+00	2570.00
IUUC-Ptr-091008	Pan troglodytes	58.33	0.00e+00	2380.00
IUUC-Pan-092404	Papio anubis	59.08	0.00e+00	2401.00
IUUC-Psi-093281	Pelodiscus sinensis	62.49	0.00e+00	2524.00
IUUC-Pma-094424	Petromyzon marinus	60.14	5.00e-98	348.00
IUUC-Pfo-096073	Poecilia formosa	58.05	0.00e+00	2410.00
IUUC-Pab-097900	Pongo abelii	58.87	0.00e+00	2392.00
IUUC-Pca-100177	Procavia capensis	59.47	0.00e+00	1048.00
IUUC-Pva-102880	Pteropus vampyrus	56.52	0.00e+00	2177.00
IUUC-Rno-105002	Rattus norvegicus	63.03	0.00e+00	2559.00
IUUC-Sha-107105	Sarcophilus harrisii	61.47	0.00e+00	2382.00
IUUC-Sar-113401	Sorex araneus	53.45	3.00e-171	595.00
IUUC-Ssc-116282	Sus scrofa	63.07	0.00e+00	2482.00
IUUC-Tgu-116807	Taeniopygia guttata	63.34	0.00e+00	2538.00
IUUC-Tru-118040	Takifugu rubripes	60.19	0.00e+00	2395.00
IUUC-Tsy-118941	Tarsius syrichta	51.53	0.00e+00	1715.00
IUUC-Tni-120118	Tetraodon nigroviridis	59.40	0.00e+00	2413.00
IUUC-Tbe-127467	Tupaia belangeri	53.83	0.00e+00	1095.00
IUUC-Ttr-129138	Tursiops truncatus	56.72	0.00e+00	2204.00
IUUC-Vpa-130083	Vicugna pacos	54.69	0.00e+00	2091.00
IUUC-Xtr-131835	Xenopus tropicalis	58.70	0.00e+00	2419.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence