iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	GXD
DNA & RNA Element
AREsite	microRNA	TRANSFAC	RepTar
RAID2
Protein-protein Interaction
IID	Mentha
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/SCF/F-box	27.78	2.00e-14	75.90	IUUC-Spo-108376

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Mus musculus

Functional Description
(View)

Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.

Protein Sequence
(Fasta)

MASLRSATPR LRSYFRDKYI PQICEALLCG LLVTCPEDPL KYLEHMILAI IKRGLENLLW 60
DTCIHPSLKS RVRRLSETYL DELFGLDDQL VTPELMIKAC TFYTGHLVKT HFSGWKKVAI 120

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Nucleotide Sequence
(Fasta)

CCTCCTTTGT GGTTGCTAGG CAACGCTCCG GCGCGTCTCT CCTCCTCAAC GTGAACAGCA 60
GTAACCTATG AAACGCATTC TGAGTCCTGC TTCTGACCAT GGCTTCACTA CGCAGTGCCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0433--Leucine-rich repeat
KW-1185--Reference proteome
KW-0677--Repeat
KW-0833--Ubl conjugation pathway

Interpro

IPR003117--cAMP_dep_PK_reg_su_I/II_a/b
IPR001810--F-box_dom
IPR032675--L_dom-like
IPR001611--Leu-rich_rpt
IPR006553--Leu-rich_rpt_Cys-con_subtyp

PROSITE

Pfam

PF12937--F-box-like
PF13516--LRR_6

SMART

SM00256--FBOX
SM00367--LRR_CC

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

KEGG

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Cja-019300	Callithrix jacchus	61.63	0.00e+00	886.00
IUUC-Cfa-021192	Canis familiaris	65.66	0.00e+00	1078.00
IUUC-Cpo-022482	Cavia porcellus	63.05	0.00e+00	867.00
IUUC-Cre-022794	Chlamydomonas reinhardtii	25.62	1.00e-05	44.30
IUUC-Cin-025793	Ciona intestinalis	39.20	1.00e-157	550.00
IUUC-Csv-026303	Ciona savignyi	40.31	6.00e-164	571.00
IUUC-Eeu-035252	Erinaceus europaeus	49.77	2.00e-107	383.00
IUUC-Fca-035625	Felis catus	62.04	0.00e+00	982.00
IUUC-Gga-040609	Gallus gallus	44.56	0.00e+00	661.00
IUUC-Loc-052402	Lepisosteus oculatus	46.49	4.00e-143	501.00
IUUC-Mmr-061592	Microcebus murinus	59.70	0.00e+00	852.00
IUUC-Mlu-067940	Myotis lucifugus	60.72	0.00e+00	891.00
IUUC-Ocu-073848	Oryctolagus cuniculus	62.50	0.00e+00	1048.00
IUUC-Oga-089110	Otolemur garnettii	69.12	0.00e+00	746.00
IUUC-Oar-089635	Ovis aries	64.68	0.00e+00	1044.00
IUUC-Pab-098377	Pongo abelii	62.99	0.00e+00	944.00
IUUC-Pva-102941	Pteropus vampyrus	63.96	0.00e+00	1080.00
IUUC-Pte-104086	Pyrenophora teres	27.16	2.00e-33	137.00
IUUC-Pyt-104451	Pyrenophora triticirepentis	26.94	4.00e-33	136.00
IUUC-Sha-107390	Sarcophilus harrisii	52.15	9.00e-149	520.00
IUUC-Spo-108376	Schizosaccharomyces pombe	25.66	5.00e-15	75.90
IUUC-Tsy-119620	Tarsius syrichta	65.96	0.00e+00	737.00

Created Date

25-Jun-2017

Functional Description