iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Component of TORC2, which regulates multiple cellular processes to control cell growth in response to environmental signals. TORC2 is required for cell survival under various stress conditions. TORC2 positively controls G1 cell-cycle arrest, sexual development and amino acid uptake. Positively regulates amino acid uptake through the control of expression of amino acid permeases.

Protein Sequence
(Fasta)

MKPVRRGQTD TALDISSHAK TNGDFIKKMN TTDSKRLKLL EDLKGKLEVE CKIRDGAETL 60
LQVFDTNFKK ETKERKEMLK KKCTDELESS KKKIEELVSS IESFQGENGE AKTGSTSLTR 120

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Nucleotide Sequence
(Fasta)

CGTTGGGGTA TCCATGAGCA TACGAGCATA GTTCGCAAGC ATTATCATTT TAGGACTCTT 60
CACAATCTTA AGTTATTATT TAAGTGTTAA TATCTTTAAT TTTACTAGAT TGCTTAAAAA 120

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Sequence Source

Ensembl

Keyword

KW-0131--Cell cycle
KW-0181--Complete proteome
KW-0469--Meiosis
KW-0472--Membrane
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR011072--HR1_rho-bd
IPR028268--Pianissimo_fam
IPR028267--Pianissimo_N
IPR029453--Rictor_IV
IPR029451--RICTOR_M
IPR029452--RICTOR_V

Pfam

PF02185--HR1
PF14663--RasGEF_N_2
PF14666--RICTOR_M
PF14664--RICTOR_N
PF14668--RICTOR_V

SMART

SM00742--Hr1
SM01307--RICTOR_M
SM01308--RICTOR_N
SM01310--RICTOR_V

Gene Ontology

GO:0032153--C:cell division site
GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0016021--C:integral component of membrane
GO:0005634--C:nucleus
GO:0031932--C:TORC2 complex
GO:0008047--F:enzyme activator activity
GO:0031532--P:actin cytoskeleton reorganization
GO:0030010--P:establishment of cell polarity
GO:0030950--P:establishment or maintenance of actin cytoskeleton polarity
GO:0051321--P:meiotic cell cycle
GO:0051897--P:positive regulation of protein kinase B signaling
GO:0032956--P:regulation of actin cytoskeleton organization
GO:0042325--P:regulation of phosphorylation
GO:0038203--P:TORC2 signaling

KEGG

spo:SPBC12C2.02c

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-004111	Anas platyrhynchos	26.16	2.00e-76	280.00
IUUC-Aca-004885	Anolis carolinensis	27.47	2.00e-85	309.00
IUUC-Ago-007975	Ashbya gossypii	36.36	2.00e-84	305.00
IUUC-Afu-008889	Aspergillus fumigatus	35.73	0.00e+00	671.00
IUUC-Ang-009838	Aspergillus niger	35.90	0.00e+00	669.00
IUUC-Ate-010586	Aspergillus terreus	35.23	0.00e+00	668.00
IUUC-Bgr-012287	Blumeria graminis	34.92	0.00e+00	635.00
IUUC-Bta-013347	Bos taurus	27.59	8.00e-86	310.00
IUUC-Bci-013718	Botrytis cinerea	37.21	0.00e+00	677.00
IUUC-Cja-019360	Callithrix jacchus	27.67	3.00e-85	308.00
IUUC-Cpo-022258	Cavia porcellus	21.37	5.00e-09	52.80
IUUC-Csa-023568	Chlorocebus sabaeus	23.91	2.30e-01	29.30
IUUC-Cho-024748	Choloepus hoffmanni	23.25	1.00e-43	170.00
IUUC-Cin-025491	Ciona intestinalis	29.90	6.00e-49	187.00
IUUC-Csv-025990	Ciona savignyi	30.45	4.00e-27	114.00
IUUC-Cgl-026666	Colletotrichum gloeosporioides	34.39	0.00e+00	643.00
IUUC-Cne-026882	Cryptococcus neoformans	37.88	1.00e-156	545.00
IUUC-Dre-027391	Danio rerio	28.50	2.00e-92	332.00
IUUC-Dno-029612	Dasypus novemcinctus	27.28	5.00e-84	304.00
IUUC-Dor-030974	Dipodomys ordii	36.53	1.00e-36	147.00
IUUC-Ete-032905	Echinops telfairi	27.95	1.00e-82	300.00
IUUC-Eca-033490	Equus caballus	26.98	2.00e-78	285.00
IUUC-Eeu-035218	Erinaceus europaeus	23.17	6.00e-24	105.00
IUUC-Fca-035568	Felis catus	26.58	3.00e-78	285.00
IUUC-Fal-037265	Ficedula albicollis	27.74	4.00e-85	308.00
IUUC-Fox-037847	Fusarium oxysporum	33.48	1.00e-176	612.00
IUUC-Fso-038392	Fusarium solani	32.79	2.00e-180	624.00
IUUC-Gmo-039569	Gadus morhua	27.52	4.00e-79	288.00
IUUC-Ggr-039786	Gaeumannomyces graminis	34.41	3.00e-178	617.00
IUUC-Gga-040814	Gallus gallus	27.87	3.00e-85	308.00
IUUC-Gac-042152	Gasterosteus aculeatus	27.85	1.00e-82	300.00
IUUC-Hsa-046897	Homo sapiens	27.90	7.00e-85	307.00
IUUC-Itr-047870	Ictidomys tridecemlineatus	27.59	4.00e-83	301.00
IUUC-Kpa-049264	Komagataella pastoris	28.79	6.00e-68	250.00
IUUC-Lch-049566	Latimeria chalumnae	27.67	5.00e-84	304.00
IUUC-Loc-052514	Lepisosteus oculatus	28.04	1.00e-81	296.00
IUUC-Lma-053045	Leptosphaeria maculans	36.57	4.00e-177	613.00
IUUC-Laf-053388	Loxodonta africana	27.59	2.00e-84	306.00
IUUC-Mcc-055195	Macaca mulatta	26.90	3.00e-78	285.00
IUUC-Meu-056687	Macropus eugenii	33.12	8.00e-16	78.20
IUUC-Mor-056999	Magnaporthe oryzae	35.61	0.00e+00	636.00
IUUC-Mpo-057301	Magnaporthe poae	34.61	1.00e-177	615.00
IUUC-Mla-058853	Melampsora laricipopulina	36.25	6.00e-161	559.00
IUUC-Mga-059725	Meleagris gallopavo	26.62	1.00e-62	233.00
IUUC-Mmr-060679	Microcebus murinus	27.39	4.00e-85	308.00
IUUC-Mmu-063859	Mus musculus	27.89	3.00e-85	308.00
IUUC-Mlu-067734	Myotis lucifugus	27.59	2.00e-85	309.00
IUUC-Nfi-068380	Neosartorya fischeri	35.97	0.00e+00	667.00
IUUC-Ncr-068779	Neurospora crassa	34.92	2.00e-177	615.00
IUUC-Opr-071025	Ochotona princeps	30.15	8.00e-50	191.00
IUUC-Ont-072104	Oreochromis niloticus	27.63	3.00e-90	325.00
IUUC-Ocu-074388	Oryctolagus cuniculus	27.39	3.00e-85	308.00
IUUC-Ola-087503	Oryzias latipes	28.24	6.00e-92	331.00
IUUC-Oar-089642	Ovis aries	27.59	7.00e-86	310.00
IUUC-Ptr-090779	Pan troglodytes	27.67	2.00e-85	309.00
IUUC-Pan-092099	Papio anubis	27.67	2.00e-85	309.00
IUUC-Psi-093606	Pelodiscus sinensis	27.76	2.00e-84	306.00
IUUC-Pno-094990	Phaeosphaeria nodorum	32.34	0.00e+00	627.00
IUUC-Pab-098429	Pongo abelii	27.75	9.00e-84	303.00
IUUC-Pca-101045	Procavia capensis	26.63	4.00e-79	288.00
IUUC-Pva-102675	Pteropus vampyrus	28.42	9.00e-33	134.00
IUUC-Pgr-103341	Puccinia graminis	37.40	5.00e-108	384.00
IUUC-Ptt-103999	Puccinia triticina	37.42	1.00e-107	382.00
IUUC-Rno-104957	Rattus norvegicus	27.89	5.00e-86	311.00
IUUC-Sce-106173	Saccharomyces cerevisiae	34.43	3.00e-78	285.00
IUUC-Sha-107121	Sarcophilus harrisii	27.28	8.00e-85	307.00
IUUC-Sja-107806	Schizosaccharomyces japonicus	47.82	0.00e+00	961.00
IUUC-Ssl-108665	Sclerotinia sclerotiorum	39.35	3.00e-111	394.00
IUUC-Sit-110774	Setaria italica	28.17	2.40e-01	28.10
IUUC-Sar-113499	Sorex araneus	31.23	1.00e-67	250.00
IUUC-Sre-114992	Sporisorium reilianum	34.09	0.00e+00	626.00
IUUC-Ssc-115246	Sus scrofa	27.59	2.00e-85	309.00
IUUC-Tgu-116455	Taeniopygia guttata	27.74	1.00e-84	306.00
IUUC-Tru-118605	Takifugu rubripes	27.78	1.00e-79	290.00
IUUC-Tsy-119061	Tarsius syrichta	27.84	3.00e-74	272.00
IUUC-Tni-119726	Tetraodon nigroviridis	27.55	9.00e-78	283.00
IUUC-Tre-121918	Trichoderma reesei	33.33	0.00e+00	632.00
IUUC-Tvi-122587	Trichoderma virens	32.65	8.00e-176	609.00
IUUC-Tbe-127960	Tupaia belangeri	25.97	1.00e-70	260.00
IUUC-Ttr-128848	Tursiops truncatus	27.49	4.00e-77	281.00
IUUC-Uma-129394	Ustilago maydis	33.60	1.00e-177	615.00
IUUC-Vda-129772	Verticillium dahliae	31.49	4.00e-171	593.00
IUUC-Vpa-130325	Vicugna pacos	27.00	7.00e-67	248.00
IUUC-Xtr-132777	Xenopus tropicalis	28.12	7.00e-83	301.00
IUUC-Xma-133798	Xiphophorus maculatus	27.22	2.00e-85	309.00
IUUC-Yli-134450	Yarrowia lipolytica	34.53	3.00e-165	574.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence