iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089558

Ensembl Protein ID

ENSOARP00000019007.1

UniProt Accession

W5Q8G5; W5Q8G5_SHEEP

Genbank Protein ID

ENSOARP00000019007

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01067960

Gene Name

TRAF7

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000017713.1	ENSOART00000019275.1	ENSOARP00000019007.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.40e-27	94.0	397	428
UBD/Beta-Prp	6.60e-46	157.0	465	674

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDl 30
           gH+++v+cl+  s  +ll sGs D+tikvWD+
   Q: 397  GHQGPVWCLCVySMgDLLFSGSSDKTIKVWDT 428
           8*********778889***************6 PP

UBD/Beta-Prp

   S: 76   ikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdl.etgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrl 163
           + vwd+++ + v t+++h++ v++l +s   + l sGs  + i+vwd+  t+ +l++ l+g +++v+ +v  +  ++l sGs+ +t+++
   Q: 465  LVVWDIQNLQKVNTIRAHDNPVCTLVSSH--NMLFSGS-LKAIKVWDIvGTELKLKKELTGLNHWVRALVAAQ--SYLYSGSY-QTIKI 547
           67**********************99999..9******.9*******7368888888**************99..*******9.79*** PP
   S: 164  Wdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfs..pnderlvsgssDgsiriWd 250
           Wd++t ++++ l+    +svys++++    ++v g + + + +wd++++e vrtl+gh  +v+ +++   p+++ + s+s D+s+r+W 
   Q: 548  WDIRTLDCIHVLQT-SGGSVYSIAVTN--HHIVCGTYENLIHVWDIESKEQVRTLTGHVGTVYALAVIstPDQTKVFSASYDRSLRVWS 633
           ************99.***********9..8***********************************99888******************* PP
   S: 251  lrsgdllktlqlhnssvisvavlsfgdnvlvlgsedskvniwkl 294
           +++  +++tl +h+ sv++ av   ++  l++g+ ds+v++w +
   Q: 634  MDNMICTQTLLRHQGSVTALAV---SRGRLFSGAVDSTVKVWTC 674
           *********************9...*****************86 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MSSGKGARYN RFSGGPSNLP TPDTAGTRME TTFGPAFSAV TTITKADGTS TYKQHRRTPS 60
SSSSLAYSPR DEEDSMDTPR PRCSRPRRAA RLAGPGAGCP QPQGPSPRPA WSQEPLVFAE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGCTCGG GCAAGGGCGC CCGCTACAAC CGCTTCTCCG GGGGGCCGAG CAACCTTCCC 60
ACCCCAGACA CCGCGGGGGT GAGGGCCAGG CCCCGGGGAG GGTCGCCTCT GGGCACGCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR008974--TRAF-like
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0043231--C:intracellular membrane-bounded organelle
GO:0005886--C:plasma membrane
GO:0000151--C:ubiquitin ligase complex
GO:0004842--F:ubiquitin-protein transferase activity
GO:0000185--P:activation of MAPKKK activity
GO:0006915--P:apoptotic process
GO:2001235--P:positive regulation of apoptotic signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001971	Ailuropoda melanoleuca	80.85	0.00e+00	1002.00
IUUC-Apl-004098	Anas platyrhynchos	77.64	0.00e+00	922.00
IUUC-Aca-004852	Anolis carolinensis	68.39	0.00e+00	723.00
IUUC-Ame-011275	Astyanax mexicanus	64.25	0.00e+00	687.00
IUUC-Bta-013153	Bos taurus	82.53	0.00e+00	1037.00
IUUC-Cja-019243	Callithrix jacchus	79.58	0.00e+00	971.00
IUUC-Cfa-020036	Canis familiaris	81.67	0.00e+00	1026.00
IUUC-Cpo-022194	Cavia porcellus	80.71	0.00e+00	1011.00
IUUC-Csa-023363	Chlorocebus sabaeus	81.52	0.00e+00	1026.00
IUUC-Cin-025279	Ciona intestinalis	53.03	0.00e+00	662.00
IUUC-Csv-026163	Ciona savignyi	57.52	0.00e+00	637.00
IUUC-Dre-027998	Danio rerio	79.68	0.00e+00	870.00
IUUC-Dno-029356	Dasypus novemcinctus	70.43	2.00e-82	297.00
IUUC-Dor-030750	Dipodomys ordii	79.03	0.00e+00	977.00
IUUC-Eca-033671	Equus caballus	71.65	0.00e+00	862.00
IUUC-Eeu-034765	Erinaceus europaeus	95.74	1.00e-161	563.00
IUUC-Fca-035843	Felis catus	81.38	0.00e+00	1023.00
IUUC-Fal-037237	Ficedula albicollis	76.98	0.00e+00	960.00
IUUC-Gmo-038779	Gadus morhua	69.43	0.00e+00	805.00
IUUC-Gga-040579	Gallus gallus	76.54	0.00e+00	952.00
IUUC-Gac-042233	Gasterosteus aculeatus	73.83	0.00e+00	903.00
IUUC-Ggo-045147	Gorilla gorilla	81.23	0.00e+00	1020.00
IUUC-Hsa-046117	Homo sapiens	81.09	0.00e+00	1019.00
IUUC-Itr-048899	Ictidomys tridecemlineatus	81.23	0.00e+00	1025.00
IUUC-Lch-050593	Latimeria chalumnae	74.93	0.00e+00	941.00
IUUC-Loc-052444	Lepisosteus oculatus	74.96	0.00e+00	946.00
IUUC-Laf-053499	Loxodonta africana	80.34	0.00e+00	979.00
IUUC-Mcc-055038	Macaca mulatta	81.52	0.00e+00	1025.00
IUUC-Meu-056610	Macropus eugenii	72.32	0.00e+00	680.00
IUUC-Mga-060183	Meleagris gallopavo	76.28	0.00e+00	950.00
IUUC-Mmr-061133	Microcebus murinus	78.94	0.00e+00	948.00
IUUC-Mdo-062312	Monodelphis domestica	78.77	0.00e+00	997.00
IUUC-Mmu-063844	Mus musculus	80.32	0.00e+00	988.00
IUUC-Mpu-066552	Mustela putorius furo	81.09	0.00e+00	999.00
IUUC-Mlu-067719	Myotis lucifugus	80.35	0.00e+00	1014.00
IUUC-Nle-070045	Nomascus leucogenys	80.06	0.00e+00	937.00
IUUC-Opr-070927	Ochotona princeps	79.03	0.00e+00	978.00
IUUC-Ont-072680	Oreochromis niloticus	71.10	0.00e+00	877.00
IUUC-Oan-073521	Ornithorhynchus anatinus	94.00	4.00e-54	201.00
IUUC-Ogu-077987	Oryza glumaepatula	25.54	1.00e-16	81.30
IUUC-Ola-087454	Oryzias latipes	73.31	0.00e+00	907.00
IUUC-Oga-088380	Otolemur garnettii	80.79	0.00e+00	1018.00
IUUC-Ptr-091606	Pan troglodytes	81.23	0.00e+00	1020.00
IUUC-Pan-092227	Papio anubis	81.52	0.00e+00	1025.00
IUUC-Psi-093853	Pelodiscus sinensis	68.59	0.00e+00	763.00
IUUC-Pma-094541	Petromyzon marinus	64.06	3.00e-105	374.00
IUUC-Pfo-096237	Poecilia formosa	72.86	0.00e+00	865.00
IUUC-Pab-097589	Pongo abelii	81.38	0.00e+00	1023.00
IUUC-Pca-100375	Procavia capensis	78.14	0.00e+00	967.00
IUUC-Pva-102434	Pteropus vampyrus	81.38	0.00e+00	1023.00
IUUC-Rno-105443	Rattus norvegicus	80.76	0.00e+00	993.00
IUUC-Sha-106517	Sarcophilus harrisii	78.48	0.00e+00	998.00
IUUC-Stu-112646	Solanum tuberosum	25.67	3.00e-19	89.70
IUUC-Ssc-115990	Sus scrofa	81.09	0.00e+00	1019.00
IUUC-Tgu-117222	Taeniopygia guttata	76.58	0.00e+00	946.00
IUUC-Tru-118392	Takifugu rubripes	72.94	0.00e+00	874.00
IUUC-Tni-120220	Tetraodon nigroviridis	72.34	0.00e+00	863.00
IUUC-Tca-121793	Theobroma cacao	32.48	3.00e-18	86.30
IUUC-Tbe-128045	Tupaia belangeri	97.23	5.00e-157	548.00
IUUC-Ttr-128203	Tursiops truncatus	78.45	0.00e+00	967.00
IUUC-Xtr-132043	Xenopus tropicalis	75.22	0.00e+00	989.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence