iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	GXD
DNA & RNA Element
AREsite	microRNA	TRANSFAC	RepTar
miRNAMap	RAID2
Protein-protein Interaction
IID	PINA	HINT
Post-translational Modifications (PTMs)
CPLM	dbPAF	PhosphositePlus	dbPTM
Phospho.ELM	UniProt	PHOSIDA	mUbiSiDa
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.30e-07	32.8	385	412

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 10   af.sd.tllvsGsdDgtikvWDlrtgvl 35
            f sd +++ + s +g ++vWD+ + ++
   Q: 385  TFsSDsKRIYTYSENGEVYVWDVNSRKC 412
           47778899**************987666 PP

Organism

Mus musculus

Functional Description
(View)

Involved in nucleolar processing of pre-18S ribosomal RNA.

Protein Sequence
(Fasta)

MPPERKSRTR RDRRAGATPG RKARPGSGST PAKAARSSQR TQPAEPRAAP SAGSAAAAAE 60
EEESRLRQRN RLTLEDDKPA AERCLEQLVF GDVEDDEDAL LQRLRSSRGQ LHGSSDESEV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGACTCCTTC CGGCTCCCCG GGGCCGGGCC GAGGAGAAGA GCGAGCCGCC CCGGCACATG 60
CGCAGTGGTA CTCCACGTGA ACGTCGGCGT TTTCCCCTCA GCCCTGAGGA TGCCGCCCGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0698--rRNA processing
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

SMART

SM00320--WD40

Gene Ontology

GO:0031965--C:nuclear membrane
GO:0005730--C:nucleolus
GO:0005634--C:nucleus
GO:0034388--C:Pwp2p-containing subcomplex of 90S preribosome
GO:0032040--C:small-subunit processome
GO:0003723--F:RNA binding
GO:0000462--P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

KEGG

mmu:217109

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000184	Aegilops tauschii	37.41	1.00e-76	280.00
IUUC-Aml-002252	Ailuropoda melanoleuca	83.85	0.00e+00	795.00
IUUC-Atr-002575	Amborella trichopoda	41.03	2.00e-73	270.00
IUUC-Aly-006512	Arabidopsis lyrata	36.73	6.00e-75	275.00
IUUC-Ath-007244	Arabidopsis thaliana	35.25	1.00e-71	264.00
IUUC-Ago-007895	Ashbya gossypii	24.78	2.00e-33	136.00
IUUC-Acl-008343	Aspergillus clavatus	25.38	1.00e-32	134.00
IUUC-Afl-008445	Aspergillus flavus	25.27	1.00e-41	164.00
IUUC-Aor-009986	Aspergillus oryzae	25.64	3.00e-40	160.00
IUUC-Ame-011338	Astyanax mexicanus	53.50	2.00e-145	509.00
IUUC-Bgr-012201	Blumeria graminis	28.34	3.00e-41	163.00
IUUC-Bta-013058	Bos taurus	77.54	0.00e+00	776.00
IUUC-Bci-013619	Botrytis cinerea	24.10	2.00e-34	140.00
IUUC-Bdi-014771	Brachypodium distachyon	36.68	7.00e-73	268.00
IUUC-Bol-015230	Brassica oleracea	39.11	3.00e-71	263.00
IUUC-Bra-017041	Brassica rapa	39.45	2.00e-69	256.00
IUUC-Cel-018293	Caenorhabditis elegans	28.72	8.00e-51	194.00
IUUC-Cja-019503	Callithrix jacchus	84.70	0.00e+00	744.00
IUUC-Cfa-020743	Canis familiaris	82.98	0.00e+00	773.00
IUUC-Cpo-021488	Cavia porcellus	83.57	0.00e+00	766.00
IUUC-Cre-022926	Chlamydomonas reinhardtii	34.17	5.00e-61	228.00
IUUC-Csa-023110	Chlorocebus sabaeus	84.89	0.00e+00	798.00
IUUC-Cin-025208	Ciona intestinalis	41.30	2.00e-73	269.00
IUUC-Cme-027351	Cyanidioschyzon merolae	28.08	2.00e-44	173.00
IUUC-Dre-027524	Danio rerio	47.26	1.00e-111	396.00
IUUC-Dno-029243	Dasypus novemcinctus	82.56	0.00e+00	764.00
IUUC-Dor-030110	Dipodomys ordii	68.75	0.00e+00	707.00
IUUC-Dse-031217	Dothistroma septosporum	28.38	5.00e-30	125.00
IUUC-Dme-031999	Drosophila melanogaster	31.99	5.00e-53	202.00
IUUC-Eca-034350	Equus caballus	82.92	0.00e+00	784.00
IUUC-Eeu-034991	Erinaceus europaeus	75.89	0.00e+00	716.00
IUUC-Fal-036614	Ficedula albicollis	59.01	2.00e-150	525.00
IUUC-Gmo-039183	Gadus morhua	49.48	8.00e-123	434.00
IUUC-Gga-040922	Gallus gallus	59.38	2.00e-165	575.00
IUUC-Gac-041475	Gasterosteus aculeatus	53.12	3.00e-127	448.00
IUUC-Gma-043598	Glycine max	34.15	9.00e-72	264.00
IUUC-Ggo-044517	Gorilla gorilla	85.03	0.00e+00	795.00
IUUC-Hsa-045741	Homo sapiens	84.87	0.00e+00	786.00
IUUC-Hvu-047463	Hordeum vulgare	37.85	9.00e-31	125.00
IUUC-Itr-048128	Ictidomys tridecemlineatus	84.45	0.00e+00	789.00
IUUC-Kpa-049335	Komagataella pastoris	31.11	9.00e-47	181.00
IUUC-Lch-049816	Latimeria chalumnae	60.40	2.00e-161	562.00
IUUC-Lpe-051140	Leersia perrieri	35.39	5.00e-73	268.00
IUUC-Loc-051942	Lepisosteus oculatus	54.47	7.00e-147	514.00
IUUC-Laf-054245	Loxodonta africana	84.03	0.00e+00	778.00
IUUC-Meu-056300	Macropus eugenii	66.13	4.00e-142	497.00
IUUC-Mor-057184	Magnaporthe oryzae	24.49	9.00e-31	128.00
IUUC-Mtr-058019	Medicago truncatula	36.30	3.00e-67	249.00
IUUC-Mga-060179	Meleagris gallopavo	62.96	5.00e-155	540.00
IUUC-Mvi-060435	Microbotryum violaceum	32.46	3.00e-51	196.00
IUUC-Mdo-062187	Monodelphis domestica	62.90	3.00e-172	598.00
IUUC-Mpu-066084	Mustela putorius furo	83.78	0.00e+00	793.00
IUUC-Mlu-068130	Myotis lucifugus	78.04	0.00e+00	772.00
IUUC-Nle-069743	Nomascus leucogenys	78.84	0.00e+00	727.00
IUUC-Opr-071111	Ochotona princeps	84.71	8.00e-175	606.00
IUUC-Ont-071979	Oreochromis niloticus	56.31	9.00e-140	490.00
IUUC-Ocu-073754	Oryctolagus cuniculus	79.40	0.00e+00	741.00
IUUC-Oba-075007	Oryza barthii	36.13	3.00e-72	266.00
IUUC-Obr-076447	Oryza brachyantha	35.55	7.00e-74	271.00
IUUC-Ogl-077733	Oryza glaberrima	36.13	2.00e-72	266.00
IUUC-Ogu-078828	Oryza glumaepatula	36.13	3.00e-72	266.00
IUUC-Oin-080152	Oryza indica	35.90	5.00e-72	265.00
IUUC-Olo-080983	Oryza longistaminata	40.38	1.00e-71	264.00
IUUC-Oni-082443	Oryza nivara	35.90	7.00e-72	265.00
IUUC-Opu-083771	Oryza punctata	36.83	4.00e-73	268.00
IUUC-Oru-084272	Oryza rufipogon	35.90	7.00e-72	265.00
IUUC-Osa-085885	Oryza sativa	35.99	6.00e-73	268.00
IUUC-Olu-087644	Ostreococcus lucimarinus	25.71	8.00e-19	88.20
IUUC-Oga-088834	Otolemur garnettii	83.47	0.00e+00	777.00
IUUC-Oar-089712	Ovis aries	84.02	0.00e+00	719.00
IUUC-Pan-092561	Papio anubis	85.30	0.00e+00	800.00
IUUC-Ppa-095397	Physcomitrella patens	42.72	4.00e-73	268.00
IUUC-Pfo-097068	Poecilia formosa	49.80	6.00e-136	477.00
IUUC-Pop-099471	Populus trichocarpa	36.59	2.00e-66	246.00
IUUC-Ppe-101684	Prunus persica	37.22	8.00e-70	258.00
IUUC-Pva-102851	Pteropus vampyrus	80.46	0.00e+00	757.00
IUUC-Pgr-103370	Puccinia graminis	27.33	6.00e-42	165.00
IUUC-Ptt-103838	Puccinia triticina	27.58	2.00e-41	163.00
IUUC-Rno-104910	Rattus norvegicus	90.58	0.00e+00	885.00
IUUC-Sce-106258	Saccharomyces cerevisiae	29.51	2.00e-41	163.00
IUUC-Sja-107746	Schizosaccharomyces japonicus	28.82	1.00e-46	180.00
IUUC-Spo-108268	Schizosaccharomyces pombe	30.09	7.00e-49	188.00
IUUC-Smo-108815	Selaginella moellendorffii	39.76	1.00e-73	270.00
IUUC-Sit-109706	Setaria italica	35.52	8.00e-74	271.00
IUUC-Sly-111533	Solanum lycopersicum	38.41	3.00e-76	279.00
IUUC-Stu-112853	Solanum tuberosum	38.86	4.00e-79	288.00
IUUC-Sbi-114747	Sorghum bicolor	35.45	2.00e-74	273.00
IUUC-Ssc-115916	Sus scrofa	84.24	0.00e+00	749.00
IUUC-Tgu-117291	Taeniopygia guttata	58.74	1.00e-143	503.00
IUUC-Tru-118724	Takifugu rubripes	47.11	2.00e-127	449.00
IUUC-Tsy-118928	Tarsius syrichta	72.07	2.00e-175	608.00
IUUC-Tca-121229	Theobroma cacao	37.34	5.00e-77	281.00
IUUC-Tae-125218	Triticum aestivum	37.41	1.00e-76	280.00
IUUC-Tur-126082	Triticum urartu	32.02	5.00e-46	178.00
IUUC-Ttr-128904	Tursiops truncatus	76.84	0.00e+00	683.00
IUUC-Vpa-130817	Vicugna pacos	82.77	0.00e+00	772.00
IUUC-Vvi-131395	Vitis vinifera	36.33	5.00e-79	288.00
IUUC-Xtr-132971	Xenopus tropicalis	59.00	7.00e-148	517.00
IUUC-Xma-133391	Xiphophorus maculatus	53.07	1.00e-134	473.00
IUUC-Yli-134613	Yarrowia lipolytica	31.71	4.00e-50	192.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence