iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Bta-013481

UUCD1 version

UUC-BoT-00106

Ensembl Protein ID

ENSBTAP00000008633.5

UniProt Accession

A7MBJ7; F1MEZ7; A7MBJ7_BOVIN

Genbank Protein ID

AAI51598.1

Protein Name

KLHL18 protein

Genbank Nucleotide ID

DAAA02054452

Gene Name

KLHL18

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000006573.5	ENSBTAT00000008633.5	ENSBTAP00000008633.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	1.50e-20	73.4	38	103
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	5.70e-09	35.2	137	167

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           +Dv+l++g+ +f+ah+ivLaas ++F+a+f++++ e k ++++++++++p++++al++F Y g l +
   Q: 38   CDVTLKIGDHKFSAHRIVLAASIPYFHAMFTNDMMECK-QDEIVMQGMDPSALEALINFAYNGHLAI 103
           9*************************************.************************9875 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhF 31
           + Nclg+++fA+++ c  L+daa++fi++hF
   Q: 137  PKNCLGVRQFAETMMCALLYDAANSFIHQHF 167
           68***************************** PP

Organism

Bos taurus

Protein Sequence
(Fasta)

MVEDGAEELE DLVHFSVSEL PSRGYGVMEE IRRQGKLCDV TLKIGDHKFS AHRIVLAASI 60
PYFHAMFTND MMECKQDEIV MQGMDPSALE ALINFAYNGH LAIDQQNVQS LLMGASFLQL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGTCTCGGCG GCCGAGGAAG ATGGTGGAGG ACGGCGCGGA GGAGCTGGAG GACCTGGTGC 60
ACTTCTCCGT GTCCGAGTTG CCTAGTCGCG GCTACGGCGT CATGGAGGAG ATCCGGCGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR011043--Gal_Oxase/kelch_b-propeller
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0016567--P:protein ubiquitination

KEGG

bta:517831

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001536	Ailuropoda melanoleuca	96.55	0.00e+00	1165.00
IUUC-Apl-003270	Anas platyrhynchos	88.43	0.00e+00	988.00
IUUC-Aca-005395	Anolis carolinensis	89.82	0.00e+00	1072.00
IUUC-Cel-018622	Caenorhabditis elegans	43.92	7.00e-139	487.00
IUUC-Cja-019847	Callithrix jacchus	96.20	0.00e+00	1157.00
IUUC-Cfa-020341	Canis familiaris	96.89	0.00e+00	1173.00
IUUC-Cpo-021613	Cavia porcellus	93.73	0.00e+00	1058.00
IUUC-Csa-023611	Chlorocebus sabaeus	96.20	0.00e+00	1158.00
IUUC-Cho-024605	Choloepus hoffmanni	81.27	8.00e-137	480.00
IUUC-Cin-025289	Ciona intestinalis	53.40	0.00e+00	631.00
IUUC-Dre-028248	Danio rerio	82.98	0.00e+00	1009.00
IUUC-Dno-029609	Dasypus novemcinctus	94.47	0.00e+00	1144.00
IUUC-Dor-030541	Dipodomys ordii	95.31	3.00e-148	517.00
IUUC-Dme-032107	Drosophila melanogaster	54.64	0.00e+00	650.00
IUUC-Eca-033507	Equus caballus	96.09	0.00e+00	1080.00
IUUC-Eeu-034750	Erinaceus europaeus	87.31	0.00e+00	960.00
IUUC-Fca-035731	Felis catus	96.37	0.00e+00	1165.00
IUUC-Fal-036959	Ficedula albicollis	89.10	0.00e+00	1040.00
IUUC-Gga-040166	Gallus gallus	93.12	0.00e+00	1117.00
IUUC-Ggo-044853	Gorilla gorilla	96.20	0.00e+00	1157.00
IUUC-Hsa-046437	Homo sapiens	95.85	0.00e+00	1149.00
IUUC-Itr-048529	Ictidomys tridecemlineatus	96.09	0.00e+00	1063.00
IUUC-Lch-050195	Latimeria chalumnae	77.49	0.00e+00	902.00
IUUC-Loc-051787	Lepisosteus oculatus	85.11	0.00e+00	979.00
IUUC-Laf-053489	Loxodonta africana	95.51	0.00e+00	1155.00
IUUC-Mcc-055250	Macaca mulatta	97.06	0.00e+00	1176.00
IUUC-Meu-056871	Macropus eugenii	86.75	0.00e+00	1019.00
IUUC-Mga-059425	Meleagris gallopavo	92.77	0.00e+00	1108.00
IUUC-Mmr-061394	Microcebus murinus	97.06	0.00e+00	1179.00
IUUC-Mdo-062285	Monodelphis domestica	93.29	0.00e+00	1108.00
IUUC-Mmu-063975	Mus musculus	97.24	0.00e+00	1181.00
IUUC-Mpu-066369	Mustela putorius furo	96.89	0.00e+00	1169.00
IUUC-Mlu-067832	Myotis lucifugus	92.78	0.00e+00	1050.00
IUUC-Nle-069338	Nomascus leucogenys	89.33	0.00e+00	1041.00
IUUC-Opr-071035	Ochotona princeps	82.84	0.00e+00	902.00
IUUC-Ont-071440	Oreochromis niloticus	82.11	0.00e+00	966.00
IUUC-Ola-087275	Oryzias latipes	81.25	0.00e+00	963.00
IUUC-Oga-087921	Otolemur garnettii	96.55	0.00e+00	1165.00
IUUC-Oar-089968	Ovis aries	92.07	0.00e+00	1073.00
IUUC-Ptr-091272	Pan troglodytes	96.20	0.00e+00	1157.00
IUUC-Pan-092629	Papio anubis	96.03	0.00e+00	1154.00
IUUC-Psi-093456	Pelodiscus sinensis	92.34	0.00e+00	983.00
IUUC-Pma-094509	Petromyzon marinus	68.60	0.00e+00	790.00
IUUC-Pfo-096450	Poecilia formosa	78.77	0.00e+00	954.00
IUUC-Pab-097917	Pongo abelii	96.03	0.00e+00	1155.00
IUUC-Pca-100330	Procavia capensis	96.66	6.00e-175	607.00
IUUC-Pva-103189	Pteropus vampyrus	96.55	0.00e+00	1165.00
IUUC-Pyt-104758	Pyrenophora triticirepentis	34.94	6.00e-07	47.80
IUUC-Sha-107283	Sarcophilus harrisii	93.07	0.00e+00	1073.00
IUUC-Sar-112989	Sorex araneus	95.15	0.00e+00	1062.00
IUUC-Tgu-117146	Taeniopygia guttata	80.53	0.00e+00	904.00
IUUC-Tru-118132	Takifugu rubripes	81.83	0.00e+00	945.00
IUUC-Tsy-119058	Tarsius syrichta	80.60	9.00e-137	479.00
IUUC-Tni-120892	Tetraodon nigroviridis	79.47	0.00e+00	949.00
IUUC-Tbe-127347	Tupaia belangeri	93.61	0.00e+00	1124.00
IUUC-Ttr-128343	Tursiops truncatus	74.44	0.00e+00	774.00
IUUC-Vpa-130796	Vicugna pacos	84.46	0.00e+00	978.00
IUUC-Xtr-132077	Xenopus tropicalis	81.40	0.00e+00	932.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence