iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Xtr-132607

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Kelch-like family member 5

Genbank Nucleotide ID

AAMC01083380

Gene Name

klhl5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000018507.3	ENSXETT00000040081.3	ENSXETP00000040081.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	2.00e-17	63.5	221	289
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	8.50e-09	34.6	321	351

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffah.kivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkldene 69
           +Dvil+ g+++++ah ++vL++ S++F a+f+++ +e k ++++++++v+p ++ al++++Ytg+l+++e
   Q: 221  CDVILIAGDRRIPAHsRLVLSSVSDYFAAMFTSDVREAK-QEEIKMEGVEPNALWALVQYSYTGRLELKE 289
           9**************889********************9.**************************9986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhF 31
           ++Nclgi++fAd+ +c+dL+++a++++  hF
   Q: 321  PSNCLGIRSFADAQGCTDLHKVAHNYTMEHF 351
           89************************98777 PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

VKVAYLNINI YVFKNFCTSL NMFKNPFAVL DFGYCLQISE PVLNISRMSG SRKDFDVKQI 60
LKVRWRWFGH QTAPASSMDV HHQEELLDRD QGIISAERKF LHPSELPLPL LGYRRPSNQD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTAAAAGTAG CATATTTGAA TATAAATATA TATGTTTTCA AGAATTTCTG TACCTCCTTA 60
AATATGTTTA AGAACCCATT TGCAGTGCTG GACTTTGGGT ACTGTCTCCA AATCAGTGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000220	Aegilops tauschii	32.79	4.00e-39	156.00
IUUC-Aml-001239	Ailuropoda melanoleuca	80.91	0.00e+00	1195.00
IUUC-Atr-002726	Amborella trichopoda	33.06	2.00e-42	167.00
IUUC-Apl-003930	Anas platyrhynchos	85.22	0.00e+00	1089.00
IUUC-Aca-004826	Anolis carolinensis	84.85	0.00e+00	1221.00
IUUC-Ame-011037	Astyanax mexicanus	81.45	0.00e+00	838.00
IUUC-Bta-013448	Bos taurus	82.41	0.00e+00	1232.00
IUUC-Bdi-014143	Brachypodium distachyon	35.02	2.00e-42	167.00
IUUC-Cja-019953	Callithrix jacchus	82.28	0.00e+00	1235.00
IUUC-Cfa-020335	Canis familiaris	86.26	0.00e+00	1238.00
IUUC-Cpo-021385	Cavia porcellus	85.83	0.00e+00	1234.00
IUUC-Csa-023109	Chlorocebus sabaeus	85.96	0.00e+00	1235.00
IUUC-Cho-024402	Choloepus hoffmanni	85.49	0.00e+00	1194.00
IUUC-Csv-026377	Ciona savignyi	64.30	0.00e+00	754.00
IUUC-Dre-028618	Danio rerio	82.60	0.00e+00	991.00
IUUC-Dme-032222	Drosophila melanogaster	56.44	0.00e+00	676.00
IUUC-Eca-034002	Equus caballus	86.26	0.00e+00	1239.00
IUUC-Fca-035953	Felis catus	77.53	0.00e+00	1135.00
IUUC-Fal-037331	Ficedula albicollis	93.57	0.00e+00	1142.00
IUUC-Gmo-039309	Gadus morhua	67.80	0.00e+00	932.00
IUUC-Gga-041137	Gallus gallus	94.38	0.00e+00	1142.00
IUUC-Gac-042162	Gasterosteus aculeatus	77.95	0.00e+00	892.00
IUUC-Gma-043533	Glycine max	30.71	3.00e-36	146.00
IUUC-Ggo-044697	Gorilla gorilla	80.95	0.00e+00	1208.00
IUUC-Hsa-047037	Homo sapiens	82.00	0.00e+00	1210.00
IUUC-Hvu-047224	Hordeum vulgare	31.80	2.00e-38	154.00
IUUC-Lch-050568	Latimeria chalumnae	85.43	0.00e+00	1209.00
IUUC-Lpe-051276	Leersia perrieri	27.53	4.00e-41	163.00
IUUC-Loc-052139	Lepisosteus oculatus	77.08	0.00e+00	1124.00
IUUC-Laf-054213	Loxodonta africana	86.24	0.00e+00	1239.00
IUUC-Mcc-054988	Macaca mulatta	82.63	0.00e+00	1239.00
IUUC-Mga-059394	Meleagris gallopavo	81.46	0.00e+00	1165.00
IUUC-Mmr-061186	Microcebus murinus	95.12	0.00e+00	1039.00
IUUC-Mdo-062687	Monodelphis domestica	85.83	0.00e+00	1230.00
IUUC-Mmu-063695	Mus musculus	85.67	0.00e+00	1233.00
IUUC-Mac-064682	Musa acuminata	32.35	1.00e-39	157.00
IUUC-Mpu-065886	Mustela putorius furo	82.55	0.00e+00	1245.00
IUUC-Mlu-067820	Myotis lucifugus	82.50	0.00e+00	1239.00
IUUC-Nle-069647	Nomascus leucogenys	82.55	0.00e+00	1242.00
IUUC-Opr-070814	Ochotona princeps	82.66	0.00e+00	1204.00
IUUC-Ont-071631	Oreochromis niloticus	67.68	0.00e+00	948.00
IUUC-Oan-073455	Ornithorhynchus anatinus	87.60	0.00e+00	1137.00
IUUC-Ogl-077595	Oryza glaberrima	32.54	1.00e-35	144.00
IUUC-Olo-080536	Oryza longistaminata	33.33	7.00e-37	149.00
IUUC-Osa-085891	Oryza sativa	32.94	6.00e-37	149.00
IUUC-Olu-087696	Ostreococcus lucimarinus	35.54	5.00e-31	127.00
IUUC-Oga-088236	Otolemur garnettii	81.21	0.00e+00	1231.00
IUUC-Oar-089243	Ovis aries	82.68	0.00e+00	1239.00
IUUC-Ptr-090722	Pan troglodytes	82.55	0.00e+00	1240.00
IUUC-Pan-092727	Papio anubis	85.81	0.00e+00	1233.00
IUUC-Psi-093068	Pelodiscus sinensis	86.08	0.00e+00	1233.00
IUUC-Pma-094371	Petromyzon marinus	78.43	0.00e+00	978.00
IUUC-Ppa-095209	Physcomitrella patens	29.67	9.00e-20	91.30
IUUC-Pfo-096355	Poecilia formosa	73.94	0.00e+00	897.00
IUUC-Pab-097795	Pongo abelii	95.19	0.00e+00	1054.00
IUUC-Ppe-101154	Prunus persica	33.33	2.00e-37	150.00
IUUC-Pva-103111	Pteropus vampyrus	82.44	0.00e+00	1199.00
IUUC-Rno-105085	Rattus norvegicus	85.67	0.00e+00	1228.00
IUUC-Sha-107240	Sarcophilus harrisii	85.81	0.00e+00	1228.00
IUUC-Sit-109883	Setaria italica	23.61	7.00e-16	79.00
IUUC-Sar-113739	Sorex araneus	78.92	0.00e+00	953.00
IUUC-Sbi-114612	Sorghum bicolor	30.51	4.00e-34	139.00
IUUC-Ssc-115880	Sus scrofa	75.09	0.00e+00	895.00
IUUC-Tgu-116703	Taeniopygia guttata	85.65	0.00e+00	1236.00
IUUC-Tru-117551	Takifugu rubripes	65.37	0.00e+00	902.00
IUUC-Tsy-118944	Tarsius syrichta	80.34	0.00e+00	1122.00
IUUC-Tni-120665	Tetraodon nigroviridis	77.22	0.00e+00	869.00
IUUC-Tur-126089	Triticum urartu	32.35	1.00e-38	155.00
IUUC-Ttr-128501	Tursiops truncatus	81.97	0.00e+00	1205.00
IUUC-Vpa-130295	Vicugna pacos	73.96	0.00e+00	1053.00
IUUC-Xma-133447	Xiphophorus maculatus	76.38	0.00e+00	909.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence