iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aca-004865

Ensembl Protein ID

ENSACAP00000012011.3

UniProt Accession

G1KM12; G1KM12_ANOCA

Protein Name

Uncharacterized protein

Gene Name

ARIH2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000012184.3	ENSACAT00000012256.3	ENSACAP00000012011.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RBR	2.60e-54	184.7	136	323

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RBR

   S: 1    CkvCllelsveeltvlleCehtfCkeClkqylelkikegqvteiscpaaecpekleeseikellveeelykryekllleevveadaalkw 90
           C+vC+ ++  +e++ +l+C+h+fC++C++q++++ +k+g  + +sc+a++c  +++e+ +  ll++eel+++y+++l+++++e++ +l++
   Q: 136  CAVCM-QFVRKENLLSLTCQHQFCRSCWEQHCTVLVKDGVGVGVSCMAQDCLLRTPEDFVFPLLPSEELKDKYRRYLFRDYIESHFQLQL 224
           9***9.77777888899************************************************************************* PP
   S: 91   cpapdCslvvllekeaeklevecekcgkefCveCkeewHeglsCkelkeklakteeekeeaeskelleanskkCpkCkvyieknegCnhm 180
           cp +dC +v+++++  ++ +v+c++c+++fC++C++++H++++C +++++l+k++   +++e++++++a++k+CpkC+++iekn+gCnhm
   Q: 225  CPGADCPMVIQVQEP-KARRVQCNRCNEVFCFKCRQMYHAPTDCATIRKWLTKCA---DDSETANYISAHTKDCPKCNICIEKNGGCNHM 310
           **************7.999************************************...99****************************** PP
   S: 181  tCakCkaefCwlC 193
           +C+kCk++fCw+C
   Q: 311  QCSKCKHDFCWMC 323
           ************* PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MSVDMNSQGS DSNEEDYDPN CDEEEEDEDP GDIEDYYVGV ANDVEQQGAD AFDPEEYQFT 60
CLTYKESEST LNEHMVSLAS ALKVSHAVAK LILVSFHWQI SEILERHKSN SVQLLVEARV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGGCAGACC AGTCAAATGA AGTCAAAAGA ACAATAAAGT GGTGGAGAAC GAAGGAGACA 60
TTGTATCGCT GCTCTGCAGT TTGGCGGGGC ACTAAGATGT CTGTGGACAT GAACAGCCAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR016150--Casein_kin_II_reg-sub_b-sht
IPR031127--E3_UB_ligase_RBR
IPR002867--IBR_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF01485--IBR

SMART

SM00647--IBR
SM00184--RING

Gene Ontology

GO:0031466--C:Cul5-RING ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0005654--C:nucleoplasm
GO:0000151--C:ubiquitin ligase complex
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0048588--P:developmental cell growth
GO:0071425--P:hematopoietic stem cell proliferation
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:1903955--P:positive regulation of protein targeting to mitochondrion
GO:0070936--P:protein K48-linked ubiquitination
GO:0070534--P:protein K63-linked ubiquitination
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

KEGG

acs:100558007

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001557	Ailuropoda melanoleuca	92.87	0.00e+00	887.00
IUUC-Apl-003878	Anas platyrhynchos	96.94	0.00e+00	912.00
IUUC-Bta-012901	Bos taurus	93.08	0.00e+00	885.00
IUUC-Cel-018334	Caenorhabditis elegans	49.09	3.00e-126	444.00
IUUC-Cja-019728	Callithrix jacchus	91.06	0.00e+00	880.00
IUUC-Cfa-020953	Canis familiaris	93.08	0.00e+00	887.00
IUUC-Cpo-021445	Cavia porcellus	90.85	0.00e+00	879.00
IUUC-Csa-023769	Chlorocebus sabaeus	91.08	0.00e+00	878.00
IUUC-Cho-024650	Choloepus hoffmanni	82.35	0.00e+00	752.00
IUUC-Cin-025577	Ciona intestinalis	54.42	7.00e-144	503.00
IUUC-Csv-025849	Ciona savignyi	54.55	9.00e-119	419.00
IUUC-Dre-028490	Danio rerio	80.56	0.00e+00	785.00
IUUC-Dno-029942	Dasypus novemcinctus	91.08	0.00e+00	879.00
IUUC-Dor-030134	Dipodomys ordii	82.11	6.00e-147	513.00
IUUC-Dme-031853	Drosophila melanogaster	55.06	8.00e-149	520.00
IUUC-Ete-032355	Echinops telfairi	84.21	0.00e+00	787.00
IUUC-Eca-033440	Equus caballus	92.87	0.00e+00	884.00
IUUC-Eeu-035230	Erinaceus europaeus	88.09	8.00e-114	403.00
IUUC-Fca-036308	Felis catus	86.99	0.00e+00	814.00
IUUC-Fal-036974	Ficedula albicollis	96.94	0.00e+00	912.00
IUUC-Gmo-038642	Gadus morhua	80.72	0.00e+00	778.00
IUUC-Gga-041019	Gallus gallus	96.94	0.00e+00	912.00
IUUC-Gac-042014	Gasterosteus aculeatus	79.88	0.00e+00	798.00
IUUC-Ggo-045329	Gorilla gorilla	91.28	0.00e+00	879.00
IUUC-Hsa-046712	Homo sapiens	91.08	0.00e+00	879.00
IUUC-Itr-048370	Ictidomys tridecemlineatus	93.29	0.00e+00	792.00
IUUC-Lch-049584	Latimeria chalumnae	86.06	0.00e+00	824.00
IUUC-Loc-051826	Lepisosteus oculatus	80.65	2.00e-164	571.00
IUUC-Laf-054567	Loxodonta africana	90.84	0.00e+00	882.00
IUUC-Mcc-054919	Macaca mulatta	91.08	0.00e+00	878.00
IUUC-Meu-056332	Macropus eugenii	88.82	0.00e+00	846.00
IUUC-Mga-060132	Meleagris gallopavo	96.35	0.00e+00	905.00
IUUC-Mmr-061599	Microcebus murinus	88.46	0.00e+00	842.00
IUUC-Mdo-062186	Monodelphis domestica	96.07	0.00e+00	805.00
IUUC-Mmu-064271	Mus musculus	90.65	0.00e+00	876.00
IUUC-Mpu-066827	Mustela putorius furo	93.14	0.00e+00	780.00
IUUC-Mlu-067528	Myotis lucifugus	91.45	0.00e+00	860.00
IUUC-Nle-068995	Nomascus leucogenys	91.28	0.00e+00	879.00
IUUC-Opr-070518	Ochotona princeps	91.28	0.00e+00	862.00
IUUC-Ont-071650	Oreochromis niloticus	82.07	0.00e+00	816.00
IUUC-Oan-073676	Ornithorhynchus anatinus	95.09	0.00e+00	766.00
IUUC-Ocu-073761	Oryctolagus cuniculus	91.48	0.00e+00	881.00
IUUC-Obr-076705	Oryza brachyantha	29.89	2.00e-56	213.00
IUUC-Ola-087204	Oryzias latipes	79.57	0.00e+00	794.00
IUUC-Oga-088098	Otolemur garnettii	91.89	0.00e+00	886.00
IUUC-Oar-089205	Ovis aries	93.08	0.00e+00	885.00
IUUC-Ptr-091514	Pan troglodytes	91.28	0.00e+00	879.00
IUUC-Pan-092493	Papio anubis	86.48	0.00e+00	831.00
IUUC-Psi-093024	Pelodiscus sinensis	91.30	2.00e-124	437.00
IUUC-Pfo-097256	Poecilia formosa	81.44	0.00e+00	805.00
IUUC-Pab-098504	Pongo abelii	83.98	0.00e+00	781.00
IUUC-Pca-100700	Procavia capensis	84.38	0.00e+00	783.00
IUUC-Pva-103105	Pteropus vampyrus	92.26	0.00e+00	871.00
IUUC-Rno-105289	Rattus norvegicus	91.26	0.00e+00	881.00
IUUC-Sha-107417	Sarcophilus harrisii	91.28	0.00e+00	864.00
IUUC-Sar-113042	Sorex araneus	91.15	0.00e+00	882.00
IUUC-Ssc-115362	Sus scrofa	92.87	0.00e+00	882.00
IUUC-Tgu-117469	Taeniopygia guttata	96.79	0.00e+00	863.00
IUUC-Tru-117976	Takifugu rubripes	80.59	0.00e+00	815.00
IUUC-Tsy-118876	Tarsius syrichta	74.43	1.00e-79	290.00
IUUC-Tni-119831	Tetraodon nigroviridis	80.20	0.00e+00	796.00
IUUC-Tca-121326	Theobroma cacao	29.48	3.00e-57	216.00
IUUC-Tbe-127386	Tupaia belangeri	82.19	2.00e-147	515.00
IUUC-Ttr-128315	Tursiops truncatus	92.67	0.00e+00	881.00
IUUC-Vpa-130383	Vicugna pacos	85.95	0.00e+00	788.00
IUUC-Xtr-132945	Xenopus tropicalis	90.02	0.00e+00	885.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence