iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tgu-117469

Ensembl Protein ID

ENSTGUP00000009376.1

UniProt Accession

H0ZFL4; H0ZFL4_TAEGU

Genbank Protein ID

ENSTGUP00000009376

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABQF01037872

Gene Name

ARIH2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTGUG00000009080.1	ENSTGUT00000009475.1	ENSTGUP00000009376.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RBR	5.00e-55	187.1	136	323

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RBR

   S: 1    CkvCllelsveeltvlleCehtfCkeClkqylelkikegqvteiscpaaecpekleeseikellveeelykryekllleevveadaalkw 90
           C+vC+ ++  +e++ +l+C+h+fC++C++q++++ +k+g  + +sc+a++c  +++e+ +  ll++eel+++y+++l++++ve++++l++
   Q: 136  CAVCM-QFVRKENLLSLACQHQFCRSCWEQHCTVLVKDGVGVGVSCMAQDCLLRTPEDFVFPLLPSEELKDKYRRYLFRDYVESHYQLQL 224
           9***9.77777888899************************************************************************* PP
   S: 91   cpapdCslvvllekeaeklevecekcgkefCveCkeewHeglsCkelkeklakteeekeeaeskelleanskkCpkCkvyieknegCnhm 180
           cp +dC +v+++++  ++ +v+c++c+++fC++C++++H++++C +++++l+k++   +++e++++++a++k+CpkC+++iekn+gCnhm
   Q: 225  CPGADCPMVIQVQEP-KARRVQCNRCNEVFCFKCRQMYHAPTDCATIRKWLTKCA---DDSETANYISAHTKDCPKCNICIEKNGGCNHM 310
           **************7.999************************************...99****************************** PP
   S: 181  tCakCkaefCwlC 193
           +C+kCk++fCw+C
   Q: 311  QCSKCKHDFCWMC 323
           ************* PP

Organism

Taeniopygia guttata

Protein Sequence
(Fasta)

MSVDMNSQGS DSNEEDYDPN CEEEEEDEDP GDIEDYYDGV ANDVEQQGAD AFDPEEYQFT 60
CLTYKESEST LNEHMASLAA TLKVSHAVAK LVLVSFHWQI SEILERHKSN AAQLLVEARV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCCGTGG ACATGAACAG CCAGGGCTCT GACAGCAATG AAGAGGATTA TGACCCTAAT 60
TGCGAGGAGG AGGAAGAGGA TGAGGATCCT GGGGATATTG AGGATTATTA TGATGGGGTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR016150--Casein_kin_II_reg-sub_b-sht
IPR031127--E3_UB_ligase_RBR
IPR002867--IBR_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF01485--IBR

SMART

SM00647--IBR
SM00184--RING

Gene Ontology

GO:0031466--C:Cul5-RING ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0005654--C:nucleoplasm
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0048588--P:developmental cell growth
GO:0071425--P:hematopoietic stem cell proliferation
GO:1903955--P:positive regulation of protein targeting to mitochondrion
GO:0070936--P:protein K48-linked ubiquitination
GO:0070534--P:protein K63-linked ubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001557	Ailuropoda melanoleuca	93.38	0.00e+00	843.00
IUUC-Apl-003878	Anas platyrhynchos	100.00	0.00e+00	882.00
IUUC-Aca-004865	Anolis carolinensis	96.79	0.00e+00	874.00
IUUC-Bta-012901	Bos taurus	93.59	0.00e+00	843.00
IUUC-Cel-018334	Caenorhabditis elegans	48.33	4.00e-119	421.00
IUUC-Cja-019728	Callithrix jacchus	91.47	0.00e+00	838.00
IUUC-Cfa-020953	Canis familiaris	93.59	0.00e+00	843.00
IUUC-Cpo-021445	Cavia porcellus	91.26	0.00e+00	837.00
IUUC-Csa-023769	Chlorocebus sabaeus	91.49	0.00e+00	835.00
IUUC-Cho-024650	Choloepus hoffmanni	81.91	0.00e+00	707.00
IUUC-Cin-025577	Ciona intestinalis	55.00	2.00e-136	478.00
IUUC-Csv-025849	Ciona savignyi	55.07	1.00e-111	395.00
IUUC-Dre-028490	Danio rerio	81.62	0.00e+00	750.00
IUUC-Dno-029942	Dasypus novemcinctus	91.49	0.00e+00	836.00
IUUC-Dor-030134	Dipodomys ordii	82.07	2.00e-134	471.00
IUUC-Dme-031853	Drosophila melanogaster	53.96	3.00e-140	491.00
IUUC-Ete-032355	Echinops telfairi	83.86	0.00e+00	742.00
IUUC-Eca-033440	Equus caballus	93.38	0.00e+00	841.00
IUUC-Eeu-035230	Erinaceus europaeus	87.79	2.00e-101	361.00
IUUC-Fca-036308	Felis catus	86.99	0.00e+00	772.00
IUUC-Fal-036974	Ficedula albicollis	100.00	0.00e+00	882.00
IUUC-Gmo-038642	Gadus morhua	80.62	0.00e+00	735.00
IUUC-Gga-041019	Gallus gallus	100.00	0.00e+00	882.00
IUUC-Gac-042014	Gasterosteus aculeatus	80.58	0.00e+00	766.00
IUUC-Ggo-045329	Gorilla gorilla	91.70	0.00e+00	837.00
IUUC-Hsa-046712	Homo sapiens	91.49	0.00e+00	837.00
IUUC-Itr-048370	Ictidomys tridecemlineatus	93.65	0.00e+00	753.00
IUUC-Lch-049584	Latimeria chalumnae	87.08	0.00e+00	788.00
IUUC-Loc-051826	Lepisosteus oculatus	80.38	2.00e-164	570.00
IUUC-Laf-054567	Loxodonta africana	90.81	0.00e+00	838.00
IUUC-Mcc-054919	Macaca mulatta	91.49	0.00e+00	835.00
IUUC-Meu-056332	Macropus eugenii	90.19	0.00e+00	810.00
IUUC-Mga-060132	Meleagris gallopavo	99.36	0.00e+00	877.00
IUUC-Mmr-061599	Microcebus murinus	88.54	0.00e+00	798.00
IUUC-Mdo-062186	Monodelphis domestica	97.66	0.00e+00	768.00
IUUC-Mmu-064271	Mus musculus	90.62	0.00e+00	831.00
IUUC-Mpu-066827	Mustela putorius furo	94.03	0.00e+00	741.00
IUUC-Mlu-067528	Myotis lucifugus	91.67	0.00e+00	815.00
IUUC-Nle-068995	Nomascus leucogenys	91.70	0.00e+00	837.00
IUUC-Opr-070518	Ochotona princeps	91.49	0.00e+00	816.00
IUUC-Ont-071650	Oreochromis niloticus	82.01	0.00e+00	778.00
IUUC-Oan-073676	Ornithorhynchus anatinus	95.83	0.00e+00	725.00
IUUC-Ocu-073761	Oryctolagus cuniculus	91.91	0.00e+00	839.00
IUUC-Obr-076705	Oryza brachyantha	30.34	5.00e-58	218.00
IUUC-Ola-087204	Oryzias latipes	80.72	0.00e+00	757.00
IUUC-Oga-088098	Otolemur garnettii	92.34	0.00e+00	845.00
IUUC-Oar-089205	Ovis aries	93.59	0.00e+00	843.00
IUUC-Ptr-091514	Pan troglodytes	91.70	0.00e+00	837.00
IUUC-Pan-092493	Papio anubis	86.67	0.00e+00	789.00
IUUC-Psi-093024	Pelodiscus sinensis	94.07	6.00e-127	446.00
IUUC-Pfo-097256	Poecilia formosa	81.34	0.00e+00	768.00
IUUC-Pab-098504	Pongo abelii	84.04	0.00e+00	740.00
IUUC-Pop-099547	Populus trichocarpa	30.85	4.00e-54	205.00
IUUC-Pca-100700	Procavia capensis	84.26	0.00e+00	739.00
IUUC-Pva-103105	Pteropus vampyrus	92.74	0.00e+00	829.00
IUUC-Rno-105289	Rattus norvegicus	91.04	0.00e+00	833.00
IUUC-Sha-107417	Sarcophilus harrisii	92.55	0.00e+00	825.00
IUUC-Sar-113042	Sorex araneus	91.56	0.00e+00	840.00
IUUC-Ssc-115362	Sus scrofa	93.38	0.00e+00	840.00
IUUC-Tru-117976	Takifugu rubripes	82.03	0.00e+00	779.00
IUUC-Tsy-118876	Tarsius syrichta	75.34	3.00e-80	291.00
IUUC-Tni-119831	Tetraodon nigroviridis	81.18	0.00e+00	758.00
IUUC-Tca-121326	Theobroma cacao	28.44	3.00e-58	219.00
IUUC-Tbe-127386	Tupaia belangeri	82.81	7.00e-148	516.00
IUUC-Ttr-128315	Tursiops truncatus	93.38	0.00e+00	840.00
IUUC-Vpa-130383	Vicugna pacos	85.90	0.00e+00	745.00
IUUC-Xtr-132945	Xenopus tropicalis	90.60	0.00e+00	848.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence