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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Spo-108249
UUCD1 version UUC-ScP-00141
Ensembl Protein ID SPBC1289.11.1:pep
UniProt Accession O94620; CWF17_SCHPO
Genbank Protein ID CAB38691.2
Protein Name Pre-mRNA-splicing factor cwf17; Complexed with cdc5 protein 17
Genbank Nucleotide ID CU329671
Gene Name spf38; cwf17; SPBC1289.11
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
SPBC1289.11 SPBC1289.11.1 SPBC1289.11.1:pep
Annotation
mRNA Expression
GEO
Protein-protein Interaction
iRefIndexHINTMentha
Protein 3D Structure
PDBMMDB
Protein Expression/Proteomics
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 1.40e-31 105.3 133 173
UBD/Beta-Prp 1.80e-57 192.9 94 335
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf....sdtllvsGsdDgtikvWDlrtgvllks 38
           gH++ v++l+     s  ll s sdD+t+kvWD r+ +++k+
   Q: 133  GHAGVVNALDVlkvgS-ELLTSVSDDCTMKVWDSRSKDCIKT 173
           8********9669633.9******************999875 PP
   

   UBD/Beta-Prp
   S: 11   svitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgk.ilvtgseDrtikvwdlstgkcvhtlkghedsvlsls 101
           + it++++s+d++++  +s d  +  wd+ +g+++r+ +gh + v+a++  + g+ +l ++s+D t kvwd ++ +c+ t++ +++ +++++
   Q: 94   GAITDLQWSRDSRVVYCSSSDTHLMSWDAVSGQKIRKHKGHAGVVNALDVLKVGSeLLTSVSDDCTMKVWDSRSKDCIKTIE-EKYPLTAVA 184
           5799*********************************************999888688999999******************.********* PP
   S: 102  fspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl....ktgkllrtltgghtdsvysls.. 187
           + ++g  + +G+ d  i++wdl+++ c++ +l+gh+++++++++++dg+ l s s D+tvr++d+    + ++ l+ ++g+ +++ + l   
   Q: 185  IAQQGTQVFIGGIDGAIKIWDLRNNHCSH-VLKGHKDIITSLAISKDGSSLLSNSMDNTVRIFDVkpfaSAQRQLQIFEGAIHGQEHNLLgv 275
           *****************************.***********************************966656666666655555555544466 PP
   S: 188  .fdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsir 247
            +++n++++ +gs d+ v +w+  tg+  + l gh+  v+ v+f+p++++++s+ssD++i+
   Q: 276  aWSRNSRFVGAGSSDKNVYVWSA-TGDLRYVLPGHEGSVNHVDFHPHQDIILSCSSDRTIF 335
           6*********************9.9**********************************97 PP
   
Organism Schizosaccharomyces pombe
Functional Description
(View)

Functional Description


     Belongs to the 40S cdc5-associated complex (or cwf complex), a spliceosome sub-complex reminiscent of a late-stage spliceosome composed of the U2, U5 and U6 snRNAs and at least brr2, cdc5, cwf2/prp3, cwf3/syf1, cwf4/syf3, cwf5/ecm2, spp42/cwf6, cwf7/spf27, cwf8, cwf9, cwf10, cwf11, cwf12, prp45/cwf13, cwf14, cwf15, cwf16, cwf17, cwf18, cwf19, cwf20, cwf21, cwf22, cwf23, cwf24, cwf25, cwf26, cyp7/cwf27, cwf28, cwf29/ist3, lea1, msl1, prp5/cwf1, prp10, prp12/sap130, prp17, prp22, sap61, sap62, sap114, sap145, slu7, smb1, smd1, smd3, smf1, smg1 and syf2.
 Belongs to the 40S cdc5-associated complex (or cwf complex), a spliceosome sub-complex reminiscent of a late-stage spliceosome composed of the U2, U5 and U6 snRNAs and at least brr2, cdc5, cwf2/prp3, cwf3/syf1, cwf4/syf3, cwf5/ecm2, spp42/cwf6, cwf7/spf27, cwf8, cwf9, cwf10, cwf11, cwf12, prp45/cwf13, cwf14, cwf15, cwf16, cwf17, cwf18, cwf19, cwf20, cwf21, cwf22, cwf23, cwf24, cwf25, cwf26, cyp7/cwf27, cwf28, cwf29/ist3, lea1, msl1, prp5/cwf1, prp10, prp12/sap130, prp17, prp22, sap61, sap62, sap114, sap145, slu7, smb1, smd1, smd3, smf1, smg1 and syf2.
Protein Sequence
(Fasta)
MDKRKESESA TNGHLVKRIR IQDSSLITEG SVLQRTSDLN VPNLQMFGHT AEVLVARFDP 60
SGSYFASGGM DRQILLWNVF GDVKNYGVLN GCKGAITDLQ WSRDSRVVYC SSSDTHLMSW 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Spo-108249|E3,WD_repeat;UBD,Beta-Prp|Schizosaccharomyces pombe
Please wait for a moment...
Nucleotide Sequence
(Fasta)
AAATTTTTAG GGATTTTGCC TGTAATCAAA ATGTTGTTCA TATAAATTCT ACTTTAAGTC 60
CTGTTTATAG GAATGAGCTC ATCATTCCTC GTTATTTGAA CACCAAAGAA AAGTCCGATT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Spo-108249|E3,WD_repeat;UBD,Beta-Prp|Schizosaccharomyces pombe
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0002--3D-structure
KW-0181--Complete proteome
KW-0507--mRNA processing
KW-0508--mRNA splicing
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat
Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF00400--WD40
PRINTS

PR00320--GPROTEINBRPT
SMART

SM00320--WD40
Gene Ontology

GO:0005634--C:nucleus
GO:0071014--C:post-mRNA release spliceosomal complex
GO:0005681--C:spliceosomal complex
GO:0005682--C:U5 snRNP
GO:0006397--P:mRNA processing
GO:0008380--P:RNA splicing
KEGG spo:SPBC1289.11
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000138 Aegilops tauschii 43.32 4.00e-76 276.00
IUUC-Aml-001428 Ailuropoda melanoleuca 43.64 6.00e-70 255.00
IUUC-Atr-003164 Amborella trichopoda 43.17 7.00e-76 275.00
IUUC-Apl-003447 Anas platyrhynchos 43.86 7.00e-70 254.00
IUUC-Aca-004270 Anolis carolinensis 40.58 5.00e-70 256.00
IUUC-Aly-005659 Arabidopsis lyrata 43.46 1.00e-76 277.00
IUUC-Ath-006764 Arabidopsis thaliana 43.79 8.00e-77 278.00
IUUC-Acl-008324 Aspergillus clavatus 46.47 1.00e-91 327.00
IUUC-Afl-008607 Aspergillus flavus 49.33 4.00e-88 315.00
IUUC-Afu-008998 Aspergillus fumigatus 47.65 4.00e-92 329.00
IUUC-Ani-009363 Aspergillus nidulans 47.35 3.00e-92 329.00
IUUC-Ang-009513 Aspergillus niger 50.00 1.00e-82 297.00
IUUC-Aor-010237 Aspergillus oryzae 47.65 4.00e-93 332.00
IUUC-Ate-010374 Aspergillus terreus 43.70 3.00e-79 286.00
IUUC-Ame-010728 Astyanax mexicanus 40.41 6.00e-72 262.00
IUUC-Bgr-012297 Blumeria graminis 47.79 8.00e-72 261.00
IUUC-Bta-012433 Bos taurus 44.12 2.00e-75 273.00
IUUC-Bci-013763 Botrytis cinerea 49.03 1.00e-91 327.00
IUUC-Bdi-014490 Brachypodium distachyon 43.97 6.00e-77 278.00
IUUC-Bol-016479 Brassica oleracea 43.00 5.00e-77 278.00
IUUC-Bra-017219 Brassica rapa 43.32 2.00e-77 280.00
IUUC-Cel-018467 Caenorhabditis elegans 44.81 8.00e-75 271.00
IUUC-Cja-019308 Callithrix jacchus 43.79 4.00e-75 273.00
IUUC-Cfa-020998 Canis familiaris 44.12 2.00e-75 273.00
IUUC-Cpo-021580 Cavia porcellus 44.12 2.00e-75 274.00
IUUC-Cre-022859 Chlamydomonas reinhardtii 42.86 9.00e-75 271.00
IUUC-Csa-023456 Chlorocebus sabaeus 43.79 4.00e-75 272.00
IUUC-Cho-024644 Choloepus hoffmanni 44.44 6.00e-76 275.00
IUUC-Cin-025463 Ciona intestinalis 45.60 2.00e-78 284.00
IUUC-Cgl-026497 Colletotrichum gloeosporioides 49.84 1.00e-93 334.00
IUUC-Cne-026780 Cryptococcus neoformans 36.86 5.00e-60 222.00
IUUC-Dre-027671 Danio rerio 42.48 1.00e-77 281.00
IUUC-Dno-029769 Dasypus novemcinctus 44.12 2.00e-75 273.00
IUUC-Dse-031316 Dothistroma septosporum 46.15 1.00e-87 314.00
IUUC-Dme-031756 Drosophila melanogaster 42.19 2.00e-78 284.00
IUUC-Ete-032753 Echinops telfairi 41.83 3.00e-65 240.00
IUUC-Eca-033979 Equus caballus 44.12 2.00e-75 273.00
IUUC-Eeu-034862 Erinaceus europaeus 50.00 1.00e-34 138.00
IUUC-Fca-036110 Felis catus 42.41 1.00e-59 221.00
IUUC-Fal-037648 Ficedula albicollis 43.14 1.00e-73 268.00
IUUC-Fox-037861 Fusarium oxysporum 48.86 9.00e-95 338.00
IUUC-Fso-038405 Fusarium solani 47.56 5.00e-92 328.00
IUUC-Gmo-039383 Gadus morhua 41.86 1.00e-73 268.00
IUUC-Ggr-040082 Gaeumannomyces graminis 43.43 1.00e-84 304.00
IUUC-Gga-040785 Gallus gallus 43.46 2.00e-74 270.00
IUUC-Gac-041645 Gasterosteus aculeatus 40.64 6.00e-72 262.00
IUUC-Gma-043672 Glycine max 44.30 1.00e-76 277.00
IUUC-Ggo-044800 Gorilla gorilla 39.04 4.00e-56 209.00
IUUC-Hsa-045918 Homo sapiens 43.79 4.00e-75 272.00
IUUC-Hvu-047342 Hordeum vulgare 43.65 8.00e-77 278.00
IUUC-Itr-048047 Ictidomys tridecemlineatus 39.29 2.00e-35 139.00
IUUC-Kpa-049149 Komagataella pastoris 34.63 5.00e-42 162.00
IUUC-Lch-050395 Latimeria chalumnae 44.12 2.00e-78 283.00
IUUC-Lpe-051275 Leersia perrieri 44.63 1.00e-78 285.00
IUUC-Loc-052666 Lepisosteus oculatus 43.14 1.00e-68 251.00
IUUC-Lma-053129 Leptosphaeria maculans 44.76 3.00e-89 319.00
IUUC-Laf-054512 Loxodonta africana 44.12 2.00e-75 273.00
IUUC-Mcc-055819 Macaca mulatta 43.65 3.00e-75 273.00
IUUC-Meu-056350 Macropus eugenii 39.54 2.00e-61 227.00
IUUC-Mor-057063 Magnaporthe oryzae 44.25 2.00e-88 317.00
IUUC-Mpo-057369 Magnaporthe poae 42.86 8.00e-84 301.00
IUUC-Mtr-058228 Medicago truncatula 44.63 1.00e-76 277.00
IUUC-Mla-059093 Melampsora laricipopulina 40.37 2.00e-61 227.00
IUUC-Mga-059719 Meleagris gallopavo 43.46 1.00e-74 270.00
IUUC-Mvi-060285 Microbotryum violaceum 34.92 5.00e-56 209.00
IUUC-Mmr-061685 Microcebus murinus 41.50 1.00e-66 244.00
IUUC-Mdo-062121 Monodelphis domestica 44.44 2.00e-75 273.00
IUUC-Mmu-063216 Mus musculus 43.79 3.00e-75 273.00
IUUC-Mac-065463 Musa acuminata 40.39 2.00e-67 247.00
IUUC-Mpu-066390 Mustela putorius furo 44.12 2.00e-75 273.00
IUUC-Mlu-067686 Myotis lucifugus 41.38 8.00e-71 258.00
IUUC-Nfi-068509 Neosartorya fischeri 47.35 3.00e-92 329.00
IUUC-Ncr-068870 Neurospora crassa 45.71 2.00e-94 337.00
IUUC-Nle-069539 Nomascus leucogenys 43.79 3.00e-75 273.00
IUUC-Opr-070555 Ochotona princeps 36.81 7.00e-61 225.00
IUUC-Ont-071490 Oreochromis niloticus 42.18 4.00e-72 262.00
IUUC-Oan-073044 Ornithorhynchus anatinus 40.32 1.00e-58 218.00
IUUC-Ocu-073764 Oryctolagus cuniculus 43.97 1.00e-75 274.00
IUUC-Oba-075704 Oryza barthii 43.65 1.00e-77 281.00
IUUC-Obr-076455 Oryza brachyantha 43.97 1.00e-77 281.00
IUUC-Ogl-077382 Oryza glaberrima 43.65 1.00e-77 280.00
IUUC-Ogu-078739 Oryza glumaepatula 43.65 8.00e-78 281.00
IUUC-Oin-079072 Oryza indica 43.65 8.00e-78 281.00
IUUC-Olo-080809 Oryza longistaminata 43.65 8.00e-78 281.00
IUUC-Ome-081677 Oryza meridionalis 43.65 6.00e-78 281.00
IUUC-Oni-082937 Oryza nivara 43.65 8.00e-78 281.00
IUUC-Opu-083510 Oryza punctata 43.65 8.00e-78 281.00
IUUC-Oru-084360 Oryza rufipogon 43.65 8.00e-78 281.00
IUUC-Osa-085640 Oryza sativa 43.65 6.00e-78 281.00
IUUC-Ola-086504 Oryzias latipes 44.44 5.00e-73 265.00
IUUC-Olu-087869 Ostreococcus lucimarinus 36.88 2.00e-48 183.00
IUUC-Oga-088773 Otolemur garnettii 44.44 7.00e-76 275.00
IUUC-Oar-089677 Ovis aries 43.69 7.00e-74 268.00
IUUC-Ptr-090724 Pan troglodytes 43.84 3.00e-70 256.00
IUUC-Pan-092683 Papio anubis 43.79 4.00e-75 272.00
IUUC-Psi-093415 Pelodiscus sinensis 43.79 4.00e-75 272.00
IUUC-Pma-094562 Petromyzon marinus 44.12 1.00e-80 291.00
IUUC-Pno-095014 Phaeosphaeria nodorum 47.47 5.00e-88 316.00
IUUC-Ppa-095822 Physcomitrella patens 45.11 4.00e-79 286.00
IUUC-Pfo-096579 Poecilia formosa 44.44 1.00e-72 264.00
IUUC-Pab-098313 Pongo abelii 43.79 4.00e-75 272.00
IUUC-Pop-099747 Populus trichocarpa 42.67 3.00e-75 273.00
IUUC-Pca-100871 Procavia capensis 39.07 3.00e-55 206.00
IUUC-Ppe-101389 Prunus persica 43.65 5.00e-76 275.00
IUUC-Pva-102468 Pteropus vampyrus 36.27 2.00e-53 200.00
IUUC-Pgr-103523 Puccinia graminis 39.50 1.00e-66 244.00
IUUC-Ptt-103930 Puccinia triticina 41.25 2.00e-66 243.00
IUUC-Pte-104299 Pyrenophora teres 45.20 7.00e-91 325.00
IUUC-Pyt-104564 Pyrenophora triticirepentis 46.05 2.00e-92 330.00
IUUC-Rno-105796 Rattus norvegicus 43.79 8.00e-75 271.00
IUUC-Sha-107191 Sarcophilus harrisii 44.44 2.00e-75 273.00
IUUC-Sja-107952 Schizosaccharomyces japonicus 51.62 2.00e-102 363.00
IUUC-Ssl-108448 Sclerotinia sclerotiorum 48.57 5.00e-91 325.00
IUUC-Sit-110805 Setaria italica 43.32 4.00e-77 279.00
IUUC-Sly-111567 Solanum lycopersicum 42.81 4.00e-75 272.00
IUUC-Stu-112562 Solanum tuberosum 42.81 2.00e-75 273.00
IUUC-Sar-112991 Sorex araneus 42.01 4.00e-49 185.00
IUUC-Sbi-114010 Sorghum bicolor 43.32 4.00e-77 279.00
IUUC-Sre-114947 Sporisorium reilianum 36.42 6.00e-61 226.00
IUUC-Ssc-115371 Sus scrofa 44.12 2.00e-75 273.00
IUUC-Tgu-117429 Taeniopygia guttata 41.29 1.00e-72 264.00
IUUC-Tru-118081 Takifugu rubripes 44.77 9.00e-74 268.00
IUUC-Tsy-119101 Tarsius syrichta 39.22 4.00e-62 229.00
IUUC-Tni-120532 Tetraodon nigroviridis 42.40 3.00e-74 270.00
IUUC-Tca-121373 Theobroma cacao 43.97 8.00e-77 278.00
IUUC-Tre-122050 Trichoderma reesei 51.14 5.00e-96 342.00
IUUC-Tvi-122394 Trichoderma virens 48.32 3.00e-89 319.00
IUUC-Tae-124661 Triticum aestivum 43.18 6.00e-75 271.00
IUUC-Tme-126998 Tuber melanosporum 45.79 4.00e-87 312.00
IUUC-Tbe-128032 Tupaia belangeri 44.12 2.00e-75 273.00
IUUC-Ttr-129102 Tursiops truncatus 42.58 3.00e-59 220.00
IUUC-Uma-129363 Ustilago maydis 37.31 3.00e-62 230.00
IUUC-Vda-129891 Verticillium dahliae 45.45 1.00e-89 320.00
IUUC-Vpa-130827 Vicugna pacos 44.77 3.00e-76 276.00
IUUC-Vvi-131202 Vitis vinifera 44.30 2.00e-77 280.00
IUUC-Xtr-132769 Xenopus tropicalis 42.19 1.00e-69 254.00
IUUC-Xma-133147 Xiphophorus maculatus 43.79 6.00e-72 262.00
IUUC-Yli-134352 Yarrowia lipolytica 33.93 1.00e-31 127.00
IUUC-Zma-135294 Zea mays 43.32 4.00e-77 279.00
Created Date 25-Jun-2017

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