iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-004161

Ensembl Protein ID

ENSAPLP00000015918.1

UniProt Accession

U3J8U0; U3J8U0_ANAPL

Genbank Protein ID

ENSAPLP00000015918

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADON01025840

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000015991.1	ENSAPLT00000016725.1	ENSAPLP00000015918.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.00e-81	274.7	2645	3005

Active Site

Position(s)	Description	Evidence
2979	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 4    dlkkrlevefvgEegldlgGvtreflallskelqnpdlglf.......lysendketlqpnpdsglknpehlklFeflGrllgkalq 83
           d ++ ++++f+gEe+++++G++r+fl++++kelq+++l+l+       ++++++k+ l+p+p ++     +++lF+f+G+llg+a++
   Q: 2645 DPTYAFNIRFTGEEVHGTSGSFRHFLWQVCKELQSSSLSLLllcpssaVNKNKGKYILTPSPITY----AEEQLFHFFGQLLGIAIR 2727
           5667788*********************************9999999888888***********9....689*************** PP
   S: 84   dgrlldlplsksfyklllgkklsl.edleevdpelyks.lkeikenaesdieelgldltfs..vseei...............lget 151
            + +l+l+l +sf+k+l+g++l+   dl+e d  +y++ +k+ + n+e+++e+l+++++++  +  ++                 + 
   Q: 2728 ADVPLPLDLLPSFWKTLVGEPLDPdVDLQEADILTYNYvKKFENINDETELEALCAEIASQhlA--TEspdcpnkpcckftylTMTG 2812
           ************************99************44555566688999999999998532..334699********9655555 PP
   S: 152  keeeLkpgGenipVtneNkeeYvklvveyrlke.gikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykg 237
           +e+eL+p+G+++pV +eNk+ Y  ++ ++r++e +  e+++a+r+G+ ++ipl+ll+ +t+ e+el +cG ++i++e lk++t+y+ 
   Q: 2813 EEVELCPRGRHVPVGWENKDVYATAIRSLRMRElQTPECMTAVRAGLGSIIPLQLLTTLTPLEMELRTCGLPYINLEFLKAHTMYQV 2899
           6667*****************************99**************************************************** PP
   S: 238  gytedspaiqwFwevleefsseerkafLqFvTgssrlPl......gGfaelk....prlfvirk...dasddrlPssnTCfnyLkLP 311
           g++e++++i++Fw++le+f++ee ++f++F+++++r+P+      gG ++ +    p+++  ++    + d+r+++++TC++++kLP
   Q: 2900 GLMETDQHIEFFWSALEMFTQEELCKFIKFACNQERIPFtcpckdGGPDTAHvppyPMKIAPPDgaaGSPDSRYIRVETCMFMIKLP 2986
           *********************************************9999999998888888888*955555**************** PP
   S: 312  eYsskeilkekLlyAieet 330
           +Yss +i+ ekL+yAi+++
   Q: 2987 QYSSLDIMLEKLRYAIHYR 3005
           ****************986 PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

PINPSKMKEL ELLCSMKEVS FDGSDLENVV LALSLREKFF QEVNSLIQRT YHPLAKTKTL 60
VKSLMNRAEL LLHVTIAAQS GITRSISGTP AETPACKSAS ETKVISHAVR QPVFLRSMSA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCTATTAACC CTAGGGAAGT GATTCAGCCT GAAGTAATGG AGGAGATGGT AGTTTCATGT 60
GTGATTAAAC ACTTGAATTT GGTTGATGCA CTCCAGTCCC TGATAAACTT CCAGTATCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002256	Ailuropoda melanoleuca	92.46	0.00e+00	5087.00
IUUC-Aca-005341	Anolis carolinensis	93.26	0.00e+00	5195.00
IUUC-Ame-011574	Astyanax mexicanus	84.02	0.00e+00	3037.00
IUUC-Bta-012514	Bos taurus	90.35	0.00e+00	1796.00
IUUC-Cja-019148	Callithrix jacchus	91.71	0.00e+00	5012.00
IUUC-Cfa-020499	Canis familiaris	92.59	0.00e+00	5113.00
IUUC-Cpo-021894	Cavia porcellus	93.92	0.00e+00	2697.00
IUUC-Csa-023079	Chlorocebus sabaeus	92.63	0.00e+00	5084.00
IUUC-Cho-024415	Choloepus hoffmanni	90.52	0.00e+00	3210.00
IUUC-Dre-027452	Danio rerio	81.82	0.00e+00	3050.00
IUUC-Dno-029595	Dasypus novemcinctus	92.21	0.00e+00	5127.00
IUUC-Dor-030849	Dipodomys ordii	88.15	0.00e+00	1477.00
IUUC-Ete-032563	Echinops telfairi	85.45	0.00e+00	1548.00
IUUC-Eca-034202	Equus caballus	92.70	0.00e+00	5050.00
IUUC-Eeu-035175	Erinaceus europaeus	92.77	0.00e+00	1018.00
IUUC-Fca-036295	Felis catus	92.59	0.00e+00	5138.00
IUUC-Fal-037003	Ficedula albicollis	97.78	0.00e+00	4600.00
IUUC-Gmo-038579	Gadus morhua	84.65	0.00e+00	2858.00
IUUC-Gga-040961	Gallus gallus	98.60	0.00e+00	5481.00
IUUC-Gac-041899	Gasterosteus aculeatus	84.83	0.00e+00	2907.00
IUUC-Ggo-045099	Gorilla gorilla	92.53	0.00e+00	5143.00
IUUC-Hsa-046331	Homo sapiens	92.53	0.00e+00	5118.00
IUUC-Itr-048190	Ictidomys tridecemlineatus	89.99	0.00e+00	1999.00
IUUC-Lch-049923	Latimeria chalumnae	89.70	0.00e+00	1147.00
IUUC-Loc-052630	Lepisosteus oculatus	84.91	0.00e+00	4109.00
IUUC-Laf-053394	Loxodonta africana	92.20	0.00e+00	5161.00
IUUC-Mcc-055763	Macaca mulatta	92.59	0.00e+00	5082.00
IUUC-Meu-056039	Macropus eugenii	88.34	0.00e+00	4861.00
IUUC-Mga-059500	Meleagris gallopavo	98.31	0.00e+00	5458.00
IUUC-Mmr-060868	Microcebus murinus	87.78	0.00e+00	4839.00
IUUC-Mdo-062772	Monodelphis domestica	92.99	0.00e+00	5198.00
IUUC-Mmu-063606	Mus musculus	91.66	0.00e+00	5102.00
IUUC-Mpu-065860	Mustela putorius furo	91.18	0.00e+00	5002.00
IUUC-Mlu-067376	Myotis lucifugus	93.31	0.00e+00	3358.00
IUUC-Nle-069693	Nomascus leucogenys	90.85	0.00e+00	4987.00
IUUC-Ont-072470	Oreochromis niloticus	84.31	0.00e+00	3080.00
IUUC-Oan-073693	Ornithorhynchus anatinus	92.63	0.00e+00	5221.00
IUUC-Ocu-074032	Oryctolagus cuniculus	91.33	0.00e+00	5061.00
IUUC-Ola-087433	Oryzias latipes	82.37	0.00e+00	1430.00
IUUC-Oga-088546	Otolemur garnettii	92.53	0.00e+00	5101.00
IUUC-Oar-089643	Ovis aries	87.71	0.00e+00	713.00
IUUC-Ptr-090504	Pan troglodytes	92.59	0.00e+00	5121.00
IUUC-Pan-092543	Papio anubis	92.60	0.00e+00	5074.00
IUUC-Psi-093952	Pelodiscus sinensis	93.10	0.00e+00	5225.00
IUUC-Pfo-096356	Poecilia formosa	84.49	0.00e+00	3061.00
IUUC-Pab-098240	Pongo abelii	92.73	0.00e+00	5070.00
IUUC-Pca-100994	Procavia capensis	95.08	0.00e+00	1644.00
IUUC-Pva-102263	Pteropus vampyrus	91.57	0.00e+00	5024.00
IUUC-Rno-104888	Rattus norvegicus	91.53	0.00e+00	5061.00
IUUC-Sha-106944	Sarcophilus harrisii	92.54	0.00e+00	5225.00
IUUC-Sar-113556	Sorex araneus	83.36	0.00e+00	912.00
IUUC-Ssc-116187	Sus scrofa	92.67	0.00e+00	4940.00
IUUC-Tgu-116655	Taeniopygia guttata	97.28	0.00e+00	5402.00
IUUC-Tru-118093	Takifugu rubripes	83.07	0.00e+00	3012.00
IUUC-Tni-119739	Tetraodon nigroviridis	83.33	0.00e+00	1467.00
IUUC-Tbe-127962	Tupaia belangeri	84.77	0.00e+00	1105.00
IUUC-Ttr-128819	Tursiops truncatus	86.96	0.00e+00	2692.00
IUUC-Vpa-130482	Vicugna pacos	92.89	0.00e+00	2578.00
IUUC-Xtr-132222	Xenopus tropicalis	89.03	0.00e+00	5102.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence