iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Eca-033375

Ensembl Protein ID

ENSECAP00000004064.1

UniProt Accession

F7ASD1; F7ASD1_HORSE

Protein Name

DCN1-like protein; Defective in cullin neddylation protein 1-like protein

Gene Name

DCUN1D2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000005413.1	ENSECAT00000005761.1	ENSECAP00000004064.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/DCUN1	6.40e-79	264.6	59	233

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/DCUN1

   S: 1    vskkkleelferYkdpqed.ligieglekfcedlgvdpediavLvlawkleaatlcefsreefldgltalgcdsieklqeklktlesel 88
           v+kkkle+l++rYkdpq++ +igi+g+++fcedl++dp++++ Lv+awk++aat+cefs++ef+dg+t+lgcds++kl++ l++le+el
   Q: 59   VDKKKLEQLYSRYKDPQDEnKIGIDGIQQFCEDLSLDPASVSALVIAWKFRAATQCEFSKKEFVDGMTELGCDSTDKLKALLPRLEQEL 147
           589**************999********************************************************************* PP
   S: 89   kdeqkfkdiYrfafnfakdkgqksldldtaialwkLllaerefklldawlkfLeeekkksiskDtWnllLefskviakdlsnYdeeg 175
           kd  kfkd+Y+f+f+fak++gqk+ldl++aia+w+L+l++r fk+ld+w++fL e++k+si++DtWnllL+f ++ia+d+snYdeeg
   Q: 148  KDAVKFKDFYQFTFSFAKNPGQKGLDLEMAIAYWNLVLSGR-FKFLDLWNTFLLEHHKRSIPRDTWNLLLDFGNMIADDMSNYDEEG 233
           ****************************************9.*******************************************96 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

HKLKPSQKDK VRQFMAFTQT GERTAIYCLT QNEWKLDLAT DTFFQNPDSF HQDSMRNTVD 60
KKKLEQLYSR YKDPQDENKI GIDGIQQFCE DLSLDPASVS ALVIAWKFRA ATQCEFSKKE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CATAAGCTTA AACCATCTCA GAAGGACAAG GTCCGCCAGT TTATGGCATT TACTCAGACT 60
GGCGAAAGAA CCGCCATCTA CTGCCTGACG CAGAATGAGT GGAAACTAGA CCTGGCCACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR014764--DCN-prot
IPR011992--EF-hand-dom_pair
IPR005176--PONY_dom
IPR009060--UBA-like

PROSITE

PS51229--DCUN1

Pfam

PF03556--Cullin_binding

Gene Ontology

GO:0000151--C:ubiquitin ligase complex
GO:0097602--F:cullin family protein binding
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0032182--F:ubiquitin-like protein binding
GO:0051443--P:positive regulation of ubiquitin-protein transferase activity
GO:0045116--P:protein neddylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aca-005059	Anolis carolinensis	87.55	2.00e-124	437.00
IUUC-Cja-018854	Callithrix jacchus	90.56	2.00e-127	447.00
IUUC-Csa-023108	Chlorocebus sabaeus	90.99	8.00e-128	449.00
IUUC-Dre-028410	Danio rerio	84.07	2.00e-118	418.00
IUUC-Dno-029524	Dasypus novemcinctus	91.78	2.00e-122	431.00
IUUC-Dor-030143	Dipodomys ordii	90.13	3.00e-126	444.00
IUUC-Ggo-044972	Gorilla gorilla	89.70	3.00e-126	443.00
IUUC-Hsa-046994	Homo sapiens	88.84	5.00e-126	442.00
IUUC-Mcc-054700	Macaca mulatta	90.99	7.00e-128	449.00
IUUC-Nle-069475	Nomascus leucogenys	90.13	9.00e-127	445.00
IUUC-Oga-088621	Otolemur garnettii	91.85	3.00e-128	450.00
IUUC-Ptr-091595	Pan troglodytes	89.27	1.00e-125	441.00
IUUC-Pan-092825	Papio anubis	91.42	3.00e-128	450.00
IUUC-Pab-098197	Pongo abelii	89.95	3.00e-119	420.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence