• HOME
  • BROWSE
  • SEARCH
  • LINK
  • DOWNLOAD
  • USER GUIDE
  • Protein
  • Gene
  • Annotation
  • Classification
  • Domain Profile
  • Function
  • Protein Sequence
  • Nucleotide Sequence
  • Keyword
  • GO
  • Orthology
  • TOP

Tag Content
iUUCD ID IUUC-Ptr-090542
Ensembl Protein ID ENSPTRP00000013836.5
UniProt Accession H2QB32; H2QB32_PANTR
Genbank Protein ID ENSPTRP00000013836
Protein Name Nucleotide-binding oligomerization domain-containing protein 2
Genbank Nucleotide ID AACZ03103060
Gene Name NOD2
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSPTRG00000008106.5 ENSPTRT00000014943.5 ENSPTRP00000013836.5
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/CARD 7.10e-24 84.2 168 221
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/CARD

   S: 3    eeyrlllstlqdrvrklLdvtdvldkylseflleeekelilaaaetkgnmqaae 56
    +e+rl+++t+++r+r+lLd+++v++++l++fll++++el+++ a + +++++++
   Q: 168 DEIRLPIFTPSQRARRLLDLATVKANGLAAFLLQHVQELPVPLALPLEAATCKK 221
    8***************************************************93 PP
   

Organism Pan troglodytes
Protein Sequence
(Fasta)
MGEEGGSVSH DEEERASVLL GHSLGCEMCS QEAFQAQRSQ LVELLVSGSL EGFESVLDWL 60
LSWEVLSWED YEGFHLLGQP LSHLARRLLD TVWNKGTWAC QKLIAAAQEA QADSQSPKLH 120
It may take some time, please wait.

Protein Fasta Sequence



>IUUC-Ptr-090542|UBD,CARD|Pan troglodytes
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGGGGGAAG AGGGTGGTTC AGTCTCTCAC GATGAGGAGG AAAGAGCAAG TGTCCTCCTC 60
GGACATTCTC TGGGTAAGAG GAGCAGGCAT TGTCCTGTCT CAGCTTGATT CTCAGCCTTC 120
It may take some time, please wait.

Nucleotide Fasta Sequence



>IUUC-Ptr-090542|UBD,CARD|Pan troglodytes
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome

Interpro

IPR001315--CARD
IPR011029--DEATH-like_dom
IPR032675--L_dom-like
IPR001611--Leu-rich_rpt
IPR007111--NACHT_NTPase
IPR027417--P-loop_NTPase

PROSITE

PS50209--CARD
PS51450--LRR
PS50837--NACHT

Pfam

PF00619--CARD
PF13516--LRR_6

Gene Ontology

GO:0016323--C:basolateral plasma membrane
GO:0009986--C:cell surface
GO:0008180--C:COP9 signalosome
GO:0005856--C:cytoskeleton
GO:0005829--C:cytosol
GO:0005794--C:Golgi apparatus
GO:0031982--C:vesicle
GO:0005524--F:ATP binding
GO:0032500--F:muramyl dipeptide binding
GO:0042834--F:peptidoglycan binding
GO:0071225--P:cellular response to muramyl dipeptide
GO:0002374--P:cytokine secretion involved in immune response
GO:0042742--P:defense response to bacterium
GO:0016045--P:detection of bacterium
GO:0032498--P:detection of muramyl dipeptide
GO:0045087--P:innate immune response
GO:0030277--P:maintenance of gastrointestinal epithelium
GO:0070431--P:nucleotide-binding oligomerization domain containing 2 signaling pathway
GO:0050871--P:positive regulation of B cell activation
GO:1900017--P:positive regulation of cytokine production involved in inflammatory response
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0050718--P:positive regulation of interleukin-1 beta secretion
GO:0032740--P:positive regulation of interleukin-17 production
GO:0032755--P:positive regulation of interleukin-6 production
GO:0032757--P:positive regulation of interleukin-8 production
GO:0046330--P:positive regulation of JNK cascade
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:1901224--P:positive regulation of NIK/NF-kappaB signaling
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0032760--P:positive regulation of tumor necrosis factor production
GO:0002830--P:positive regulation of type 2 immune response
GO:0042981--P:regulation of apoptotic process

KEGG ptr:454083
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001822 Ailuropoda melanoleuca 81.83 0.00e+00 1496.00
IUUC-Ame-011021 Astyanax mexicanus 45.97 0.00e+00 878.00
IUUC-Bta-013241 Bos taurus 81.84 0.00e+00 1632.00
IUUC-Cja-019633 Callithrix jacchus 91.16 0.00e+00 1388.00
IUUC-Cfa-020039 Canis familiaris 83.42 0.00e+00 1638.00
IUUC-Cpo-022337 Cavia porcellus 80.17 0.00e+00 1544.00
IUUC-Csa-023906 Chlorocebus sabaeus 96.24 0.00e+00 1922.00
IUUC-Dre-027568 Danio rerio 48.22 0.00e+00 833.00
IUUC-Dno-029098 Dasypus novemcinctus 81.15 0.00e+00 1522.00
IUUC-Dor-031102 Dipodomys ordii 73.35 0.00e+00 701.00
IUUC-Ete-032943 Echinops telfairi 77.31 0.00e+00 1122.00
IUUC-Eca-034310 Equus caballus 84.87 0.00e+00 1631.00
IUUC-Eeu-034589 Erinaceus europaeus 83.48 5.00e-164 572.00
IUUC-Fca-036252 Felis catus 79.22 0.00e+00 818.00
IUUC-Gac-041442 Gasterosteus aculeatus 46.40 0.00e+00 818.00
IUUC-Ggo-044861 Gorilla gorilla 99.42 0.00e+00 1934.00
IUUC-Hsa-046093 Homo sapiens 98.94 0.00e+00 1925.00
IUUC-Itr-048543 Ictidomys tridecemlineatus 81.57 0.00e+00 1481.00
IUUC-Lch-049454 Latimeria chalumnae 54.00 0.00e+00 927.00
IUUC-Laf-053553 Loxodonta africana 83.89 0.00e+00 1519.00
IUUC-Mcc-055772 Macaca mulatta 96.26 0.00e+00 1857.00
IUUC-Meu-056785 Macropus eugenii 69.15 7.00e-116 411.00
IUUC-Mmr-060596 Microcebus murinus 83.67 0.00e+00 1626.00
IUUC-Mdo-062983 Monodelphis domestica 68.02 0.00e+00 1129.00
IUUC-Mmu-063951 Mus musculus 78.26 0.00e+00 1534.00
IUUC-Mpu-066412 Mustela putorius furo 83.32 0.00e+00 1632.00
IUUC-Mlu-067601 Myotis lucifugus 81.13 0.00e+00 1456.00
IUUC-Nle-069913 Nomascus leucogenys 98.03 0.00e+00 1565.00
IUUC-Opr-070999 Ochotona princeps 84.58 0.00e+00 996.00
IUUC-Ont-072512 Oreochromis niloticus 46.60 0.00e+00 884.00
IUUC-Oan-073564 Ornithorhynchus anatinus 62.40 0.00e+00 1106.00
IUUC-Ocu-074837 Oryctolagus cuniculus 86.35 0.00e+00 1645.00
IUUC-Ola-086555 Oryzias latipes 45.73 0.00e+00 815.00
IUUC-Oga-088909 Otolemur garnettii 84.13 0.00e+00 1625.00
IUUC-Oar-089315 Ovis aries 81.16 0.00e+00 1566.00
IUUC-Pan-092545 Papio anubis 95.86 0.00e+00 1883.00
IUUC-Pma-094167 Petromyzon marinus 34.49 9.00e-66 244.00
IUUC-Ppa-095344 Physcomitrella patens 32.63 1.00e-06 48.90
IUUC-Pfo-096976 Poecilia formosa 44.82 0.00e+00 829.00
IUUC-Pab-098481 Pongo abelii 98.65 0.00e+00 1914.00
IUUC-Pca-100135 Procavia capensis 77.06 0.00e+00 1304.00
IUUC-Pva-102127 Pteropus vampyrus 81.50 0.00e+00 1462.00
IUUC-Rno-105783 Rattus norvegicus 80.30 0.00e+00 1518.00
IUUC-Sar-113448 Sorex araneus 74.26 0.00e+00 927.00
IUUC-Tru-118708 Takifugu rubripes 44.54 0.00e+00 781.00
IUUC-Tni-120172 Tetraodon nigroviridis 37.95 2.00e-33 135.00
IUUC-Tbe-127661 Tupaia belangeri 87.15 0.00e+00 857.00
IUUC-Ttr-128318 Tursiops truncatus 77.96 0.00e+00 1454.00
IUUC-Vpa-130502 Vicugna pacos 75.53 3.00e-162 565.00
Created Date 25-Jun-2017

https://dev.news.makassarkota.go.id/public/pgsoft-demo/ https://jdih.sumbawabaratkab.go.id/lato/pg-soft-demo/ https://dev.news.makassarkota.go.id/public/slot-gacor/ http://pbb.tanahbumbukab.go.id/-/slot-gacor/ slot gacor https://siakad.unipra.ac.id/sass/slot-gacor-x500/ http://kpm.dinus.ac.id/assets/images/berita/slot/
Copyright © 2004-2017.The CUCKOO Workgroup. All Rights Reserved