iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tgu-116769

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABQF01055973

Gene Name

WDSUB1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTGUG00000012224.1	ENSTGUT00000012733.1	ENSTGUP00000012594.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	5.30e-25	87.1	402	472
E3 adaptor/Cullin RING/DCX/DWD	1.10e-37	126.2	52	87
UBD/Beta-Prp	8.20e-53	179.3	3	191

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 2    vpeeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqawceens 73
           vp+eflCpI+ elM+dPv++ +G++y+r+++e w+++ ++ +P+t+ pl++ +l+Pn tl+  i++w+e+++
   Q: 402  VPDEFLCPITRELMNDPVIATDGYSYEREAMENWISNRRS-SPMTNLPLHSLMLTPNRTLKMAISRWLETQQ 472
           8**********************************99998.***************************9986 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgv 34
           gH+  v+c++f ++   l+s+s Dgt  +WD+r+g+
   Q: 52   GHAYAVHCCCFsPSgLVLASCSTDGTSVLWDTRDGR 87
           8999*******9665779***************997 PP

UBD/Beta-Prp

   S: 43   kllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgk..cvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcl 129
           +l+++l +h++ v+ + fs++   l+t+s D+ti+v++ls++   + + l+gh + v ++ fspsg +l+s s d t  +wd++ g  l
   Q: 3    TLIHTLADHNDDVNYCAFSSS--CLATCSLDKTIRVYSLSNFAelPYSPLEGHAYAVHCCCFSPSGLVLASCSTDGTSVLWDTRDGRRL 89
           589******************..9****************76622567899************************************** PP
   S: 130  eetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtl 218
             ++++  + v++ +++p++ +l +G++D+ v lW+++++kl r  +  + +s    +f++ng+++v+gs  g++++wd +   c++  
   Q: 90   AVLEQPGASPVRVCRFSPEAAYLLAGAADGSVVLWNVQSMKLYRSGKV-KGGSLMACAFSPNGNFFVTGSSSGDLTIWDDKMR-CLYNE 176
           *888999999***********************************987.99*****************************665.***** PP
   S: 219  nghtdnvksvrfspn 233
           ++h+  v++ + s++
   Q: 177  KAHDLGVTCCDISSH 191
           *********999844 PP

Organism

Taeniopygia guttata

Protein Sequence
(Fasta)

MATLIHTLAD HNDDVNYCAF SSSCLATCSL DKTIRVYSLS NFAELPYSPL EGHAYAVHCC 60
CFSPSGLVLA SCSTDGTSVL WDTRDGRRLA VLEQPGASPV RVCRFSPEAA YLLAGAADGS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGACAT TAATTCACAC TTTAGCAGAT CATAATGATG ATGTTAATTA CTGTGCCTTC 60
TCATCGTCGT GCTTGGCTAC ATGTTCCTTG GACAAAACAA TTCGCGTCTA TTCTTTGAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001660--SAM
IPR013761--SAM/pointed
IPR003613--Ubox_domain
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50105--SAM_DOMAIN
PS51698--U_BOX
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF07647--SAM_2
PF04564--U-box
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00454--SAM
SM00504--Ubox
SM00320--WD40

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

KEGG

tgu:100232488

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001614	Ailuropoda melanoleuca	73.74	0.00e+00	736.00
IUUC-Apl-003529	Anas platyrhynchos	82.56	0.00e+00	823.00
IUUC-Aca-004257	Anolis carolinensis	68.99	0.00e+00	689.00
IUUC-Ame-011357	Astyanax mexicanus	48.77	1.00e-111	396.00
IUUC-Bta-013032	Bos taurus	71.28	0.00e+00	705.00
IUUC-Cja-018743	Callithrix jacchus	72.48	0.00e+00	726.00
IUUC-Cfa-021197	Canis familiaris	73.11	0.00e+00	730.00
IUUC-Cpo-022279	Cavia porcellus	72.69	0.00e+00	725.00
IUUC-Csa-023954	Chlorocebus sabaeus	72.90	0.00e+00	729.00
IUUC-Cho-025083	Choloepus hoffmanni	59.79	2.00e-123	434.00
IUUC-Cin-025786	Ciona intestinalis	35.96	1.00e-86	313.00
IUUC-Dre-028087	Danio rerio	53.69	1.00e-137	482.00
IUUC-Dno-028919	Dasypus novemcinctus	72.06	0.00e+00	717.00
IUUC-Dor-031112	Dipodomys ordii	70.59	0.00e+00	696.00
IUUC-Ete-032405	Echinops telfairi	71.35	8.00e-146	509.00
IUUC-Eca-033254	Equus caballus	71.43	0.00e+00	712.00
IUUC-Eeu-034545	Erinaceus europaeus	68.28	0.00e+00	662.00
IUUC-Fca-035482	Felis catus	74.37	0.00e+00	740.00
IUUC-Fal-036976	Ficedula albicollis	77.85	0.00e+00	728.00
IUUC-Gmo-039213	Gadus morhua	53.19	1.00e-131	462.00
IUUC-Gga-040561	Gallus gallus	82.60	0.00e+00	816.00
IUUC-Gac-041471	Gasterosteus aculeatus	55.53	1.00e-133	469.00
IUUC-Ggo-045503	Gorilla gorilla	73.32	0.00e+00	732.00
IUUC-Hsa-045910	Homo sapiens	73.32	0.00e+00	731.00
IUUC-Itr-048214	Ictidomys tridecemlineatus	71.09	2.00e-161	561.00
IUUC-Loc-052307	Lepisosteus oculatus	56.52	8.00e-165	572.00
IUUC-Laf-053587	Loxodonta africana	71.01	0.00e+00	709.00
IUUC-Mcc-055679	Macaca mulatta	73.11	0.00e+00	731.00
IUUC-Meu-055962	Macropus eugenii	61.34	2.00e-160	558.00
IUUC-Mga-059652	Meleagris gallopavo	81.55	0.00e+00	812.00
IUUC-Mmr-060943	Microcebus murinus	70.08	0.00e+00	693.00
IUUC-Mdo-062592	Monodelphis domestica	71.61	0.00e+00	715.00
IUUC-Mmu-063577	Mus musculus	69.96	0.00e+00	682.00
IUUC-Mpu-066422	Mustela putorius furo	73.74	0.00e+00	736.00
IUUC-Mlu-067250	Myotis lucifugus	71.85	0.00e+00	713.00
IUUC-Nle-069517	Nomascus leucogenys	73.11	0.00e+00	729.00
IUUC-Opr-070776	Ochotona princeps	71.43	0.00e+00	701.00
IUUC-Ont-071821	Oreochromis niloticus	55.72	2.00e-144	504.00
IUUC-Oan-073706	Ornithorhynchus anatinus	72.42	0.00e+00	728.00
IUUC-Ocu-074766	Oryctolagus cuniculus	64.58	5.00e-178	616.00
IUUC-Ola-086531	Oryzias latipes	54.37	1.00e-137	482.00
IUUC-Oga-088388	Otolemur garnettii	71.22	0.00e+00	714.00
IUUC-Oar-089748	Ovis aries	71.49	0.00e+00	704.00
IUUC-Ptr-090616	Pan troglodytes	73.15	0.00e+00	726.00
IUUC-Pan-091769	Papio anubis	72.59	2.00e-149	521.00
IUUC-Psi-093334	Pelodiscus sinensis	77.52	0.00e+00	733.00
IUUC-Pma-094383	Petromyzon marinus	48.44	7.00e-131	460.00
IUUC-Pfo-096801	Poecilia formosa	54.47	5.00e-142	497.00
IUUC-Pab-098139	Pongo abelii	72.16	4.00e-169	586.00
IUUC-Pca-100523	Procavia capensis	61.34	2.00e-168	584.00
IUUC-Pva-102286	Pteropus vampyrus	72.27	0.00e+00	699.00
IUUC-Rno-104831	Rattus norvegicus	70.17	0.00e+00	689.00
IUUC-Sha-107499	Sarcophilus harrisii	73.32	0.00e+00	729.00
IUUC-Sar-113389	Sorex araneus	68.91	0.00e+00	679.00
IUUC-Tru-118774	Takifugu rubripes	52.88	7.00e-137	480.00
IUUC-Tsy-119595	Tarsius syrichta	61.52	7.00e-138	483.00
IUUC-Tni-119850	Tetraodon nigroviridis	55.11	7.00e-142	496.00
IUUC-Tbe-127938	Tupaia belangeri	67.11	6.00e-117	412.00
IUUC-Ttr-128193	Tursiops truncatus	72.88	8.00e-179	619.00
IUUC-Vpa-130275	Vicugna pacos	73.74	0.00e+00	732.00
IUUC-Xtr-131982	Xenopus tropicalis	60.84	1.00e-164	572.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence