iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-036616

Ensembl Protein ID

ENSFALP00000005148.1

UniProt Accession

U3JQU4; U3JQU4_FICAL

Genbank Protein ID

ENSFALP00000005148

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTO01000871

Gene Name

WSB1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000004939.1	ENSFALT00000005173.1	ENSFALP00000005148.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	9.40e-13	47.5	376	421
E3 adaptor/Cullin RING/DCX/DWD	2.60e-32	109.2	170	204
UBD/Beta-Prp	1.70e-47	161.7	135	380

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 2    sklwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlye 50
           +++w +++++ SLqhLCR+aIrr +++ ++     LP+P +  ++L y+
   Q: 376  VYFWATPRQVSSLQHLCRMAIRRVMPTSQV---RNLPIPCKVLEFLCYQ 421
           689************************777...************9887 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd..tllvsGsdDgtikvWDlrtg 33
           Ht+ v++l f +d   +lvs+s+D+t++vWDl+++
   Q: 170  HTEVVRDLTFaPDgsLILVSASRDKTLRVWDLKDD 204
           9**********8865668*************9987 PP

UBD/Beta-Prp

   S: 16   vkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgk.ilvtgseDrtikvwdls.tgkcvhtlkghedsvlslsf 102
            kf +++ llatg  +g+ik+wdv tgkll  l +h++ v++++f pdg+ ilv++s+D+t++vwdl+ +g ++ +l+gh + v+ ++f
   Q: 135  FKFGQEQLLLATGLNNGRIKIWDVYTGKLLLNLMDHTEVVRDLTFAPDGSlILVSASRDKTLRVWDLKdDGNMMKVLRGHPNWVYGCAF 223
           67889999***********************************************************9799****************** PP
   S: 103  spsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl............tggh 179
           sp+++ l s ++ + + +wd+++++ l+  l+gh+  v   +++pdg ll+++s+D++v +Wd  tg +lr++             g++
   Q: 224  SPDSSILCSVGASKAVFLWDMDKYSMLR-KLEGHHNDVVACEFSPDGALLATASYDTQVYVWDPHTGVILREFghlfppptpifaGGAN 311
           ****************************.999999999999*******************************************98889 PP
   S: 180  tdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWd 250
           ++ v+ +sf+++g +++s ++d+ v++w + ++     + +  +n ++  fs ++  l+ g++Dgs+++W 
   Q: 312  DRWVRAVSFSHDGLHVASLADDKMVRFWRIDEE--YPVQVAPLNNGLCCTFSTDGSVLAAGTQDGSVYFWA 380
           ******************************998..68899******************************2 PP

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

MLLGSPVTDL LCPPARARTV GELLAPTSPF DKKCGRENWT VAFAPDGSYL AWSQGHRVVK 60
LVPWAQCLNN FLLHGTKNGA DAVGARPPRQ GSESSPKNKP CEHVIDCGDI VWSLAFGSSV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGGGGCTCGG GCGGGGGCGG GCGGGCGCTC AGCTCATCCC GCAGCACAGC AGCGCGCTGG 60
GGGCTGCCCG CGGGGAGCGG GCGGGATCCG GGCACACGCG GCTATTGCGG GCACACGGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR020472--G-protein_beta_WD-40_rep
IPR027295--Quinoprotein_ADH-like_fam
IPR001496--SOCS_box
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50225--SOCS
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF07525--SOCS_box
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00253--SOCS
SM00969--SOCS_box
SM00320--WD40

Gene Ontology

GO:0005622--C:intracellular
GO:0035556--P:intracellular signal transduction
GO:0016567--P:protein ubiquitination

KEGG

fab:101818138

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001635	Ailuropoda melanoleuca	87.22	0.00e+00	739.00
IUUC-Apl-003903	Anas platyrhynchos	92.91	0.00e+00	803.00
IUUC-Aca-005214	Anolis carolinensis	75.54	0.00e+00	663.00
IUUC-Ame-011740	Astyanax mexicanus	73.77	0.00e+00	642.00
IUUC-Bta-013475	Bos taurus	86.49	0.00e+00	739.00
IUUC-Cja-019053	Callithrix jacchus	86.21	0.00e+00	746.00
IUUC-Cfa-020103	Canis familiaris	86.73	0.00e+00	738.00
IUUC-Cpo-022438	Cavia porcellus	86.49	0.00e+00	754.00
IUUC-Csa-024062	Chlorocebus sabaeus	86.24	0.00e+00	749.00
IUUC-Cho-024334	Choloepus hoffmanni	75.25	5.00e-180	623.00
IUUC-Cin-025590	Ciona intestinalis	40.20	7.00e-78	283.00
IUUC-Csv-026023	Ciona savignyi	39.76	2.00e-77	282.00
IUUC-Dre-028089	Danio rerio	74.26	0.00e+00	650.00
IUUC-Dno-029436	Dasypus novemcinctus	82.64	8.00e-180	622.00
IUUC-Dor-031107	Dipodomys ordii	79.36	0.00e+00	660.00
IUUC-Ete-032326	Echinops telfairi	84.52	0.00e+00	725.00
IUUC-Eca-033401	Equus caballus	86.49	0.00e+00	737.00
IUUC-Eeu-034520	Erinaceus europaeus	84.52	0.00e+00	736.00
IUUC-Fca-036386	Felis catus	86.49	0.00e+00	738.00
IUUC-Gmo-039335	Gadus morhua	71.74	5.00e-176	609.00
IUUC-Gga-040856	Gallus gallus	92.16	0.00e+00	796.00
IUUC-Gac-042140	Gasterosteus aculeatus	71.67	0.00e+00	625.00
IUUC-Ggo-044619	Gorilla gorilla	86.24	0.00e+00	748.00
IUUC-Hsa-046300	Homo sapiens	86.73	0.00e+00	749.00
IUUC-Itr-048830	Ictidomys tridecemlineatus	86.49	0.00e+00	749.00
IUUC-Lch-049550	Latimeria chalumnae	79.19	2.00e-166	577.00
IUUC-Loc-051769	Lepisosteus oculatus	75.74	0.00e+00	655.00
IUUC-Laf-054576	Loxodonta africana	86.24	0.00e+00	735.00
IUUC-Mcc-054666	Macaca mulatta	88.17	8.00e-141	492.00
IUUC-Meu-055989	Macropus eugenii	85.14	3.00e-179	620.00
IUUC-Mga-059722	Meleagris gallopavo	91.67	0.00e+00	795.00
IUUC-Mmr-060970	Microcebus murinus	86.00	0.00e+00	733.00
IUUC-Mdo-062249	Monodelphis domestica	74.51	8.00e-173	599.00
IUUC-Mmu-063742	Mus musculus	82.76	0.00e+00	713.00
IUUC-Mpu-066518	Mustela putorius furo	86.73	0.00e+00	751.00
IUUC-Mlu-068063	Myotis lucifugus	86.00	0.00e+00	730.00
IUUC-Nle-069561	Nomascus leucogenys	86.49	0.00e+00	748.00
IUUC-Opr-071158	Ochotona princeps	83.25	0.00e+00	719.00
IUUC-Ont-072542	Oreochromis niloticus	70.46	3.00e-178	617.00
IUUC-Oan-073217	Ornithorhynchus anatinus	87.22	0.00e+00	744.00
IUUC-Ocu-074251	Oryctolagus cuniculus	85.50	0.00e+00	733.00
IUUC-Ola-086549	Oryzias latipes	70.22	3.00e-179	620.00
IUUC-Oga-088382	Otolemur garnettii	86.73	0.00e+00	743.00
IUUC-Oar-090263	Ovis aries	85.01	0.00e+00	731.00
IUUC-Ptr-090922	Pan troglodytes	86.73	0.00e+00	751.00
IUUC-Pan-092518	Papio anubis	86.24	0.00e+00	749.00
IUUC-Psi-093512	Pelodiscus sinensis	89.46	0.00e+00	775.00
IUUC-Pma-094324	Petromyzon marinus	58.94	6.00e-131	460.00
IUUC-Pfo-096264	Poecilia formosa	70.87	8.00e-180	622.00
IUUC-Pab-098018	Pongo abelii	84.77	0.00e+00	732.00
IUUC-Pca-101034	Procavia capensis	84.52	0.00e+00	705.00
IUUC-Pva-102862	Pteropus vampyrus	82.92	0.00e+00	676.00
IUUC-Rno-106116	Rattus norvegicus	83.29	0.00e+00	721.00
IUUC-Sha-106952	Sarcophilus harrisii	84.50	0.00e+00	728.00
IUUC-Sar-113211	Sorex araneus	75.16	3.00e-138	484.00
IUUC-Ssc-116440	Sus scrofa	87.22	0.00e+00	741.00
IUUC-Tgu-116675	Taeniopygia guttata	94.12	0.00e+00	799.00
IUUC-Tru-118295	Takifugu rubripes	70.12	4.00e-176	610.00
IUUC-Tsy-118916	Tarsius syrichta	75.18	2.00e-178	618.00
IUUC-Tni-120302	Tetraodon nigroviridis	69.40	4.00e-172	597.00
IUUC-Tbe-127416	Tupaia belangeri	75.43	7.00e-178	616.00
IUUC-Ttr-128185	Tursiops truncatus	86.73	0.00e+00	738.00
IUUC-Xtr-132465	Xenopus tropicalis	81.82	0.00e+00	714.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence