iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-010992

Ensembl Protein ID

ENSAMXP00000019600.1

UniProt Accession

W5LID8; W5LID8_ASTMX

Genbank Protein ID

ENSAMXP00000019600

Protein Name

E3 ubiquitin-protein ligase

Genbank Nucleotide ID

APWO01041643

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000019034.1	ENSAMXT00000019600.1	ENSAMXP00000019600.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	9.10e-58	196.5	587	755

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldl 90
           ++dl++rl+v f+gEegld+gG++re+++lls+e+ np+++lf+y  +++++lq+np+s + np+hl++F f+Gr++++al++g+++d+
   Q: 587  PYDLRRRLYVIFRGEEGLDYGGLAREWFFLLSHEVLNPMYCLFEYAGKSNYCLQINPASTI-NPDHLSYFCFIGRFIAMALFHGKFIDT 674
           6799*******************************************************98.89************************* PP
   S: 91   plsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYv 174
            +s +fyk++l+kkl l+dle++dpe+y+sl +i++n   +iee++l++ fsv+ eilg++++++Lkp+G+ni Vt+eNkeeY+
   Q: 675  GFSLPFYKRMLNKKLILKDLESIDPEFYNSLIWIRDN---NIEECSLEMYFSVDMEILGKITSHDLKPDGANILVTEENKEEYI 755
           ***********************************99...9******************************************9 PP

Organism

Astyanax mexicanus

Protein Sequence
(Fasta)

MATASSRTDC SNNHGRTSQL HAIVSCAKLK RKKTLFGTAI YVEVTAEGES KKTAKSHSSS 60
SPKWEERLTL NVTPHTQLDF KVWSHHTLKA DTLLGKATLD LRQALEQHDR KLENVKEVLK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TAAATTACGT CATTGGACGT GTGGAGGGGT TTCTCTGCGG TGTGTGAATC TGGATATCAG 60
AGAGAGAGAA AGAGAGAGGG AGAGAGAGAC AGACAGACAC AGAGAGAGAG AGAGAGAGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000008--C2_dom
IPR024928--E3_ub_ligase_SMURF1
IPR000569--HECT_dom
IPR001202--WW_dom

PROSITE

PS50237--HECT
PS01159--WW_DOMAIN_1
PS50020--WW_DOMAIN_2

Pfam

PF00168--C2
PF00632--HECT
PF00397--WW

SMART

SM00239--C2
SM00119--HECTc
SM00456--WW

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aca-005388	Anolis carolinensis	69.08	0.00e+00	1007.00
IUUC-Cja-019448	Callithrix jacchus	70.53	0.00e+00	1051.00
IUUC-Eeu-035259	Erinaceus europaeus	59.26	0.00e+00	828.00
IUUC-Fal-037335	Ficedula albicollis	71.45	0.00e+00	1075.00
IUUC-Hsa-046544	Homo sapiens	69.88	0.00e+00	1040.00
IUUC-Itr-048860	Ictidomys tridecemlineatus	69.85	0.00e+00	1008.00
IUUC-Mga-059986	Meleagris gallopavo	72.34	0.00e+00	1071.00
IUUC-Nle-069188	Nomascus leucogenys	70.27	0.00e+00	1043.00
IUUC-Ocu-073891	Oryctolagus cuniculus	66.01	0.00e+00	930.00
IUUC-Ptr-090484	Pan troglodytes	69.88	0.00e+00	1040.00
IUUC-Pan-092117	Papio anubis	70.01	0.00e+00	1039.00
IUUC-Psi-093338	Pelodiscus sinensis	72.37	0.00e+00	1078.00
IUUC-Tgu-117079	Taeniopygia guttata	71.91	0.00e+00	1068.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence