iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pab-098348

Ensembl Protein ID

ENSPPYP00000008183.2

UniProt Accession

H2NQJ8; H2NQJ8_PONAB

Genbank Protein ID

ENSPPYP00000008183

Protein Name

Coronin

Genbank Nucleotide ID

ABGA01371716

Gene Name

CORO1A

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000007238.2	ENSPPYT00000008520.2	ENSPPYP00000008183.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.30e-21	74.2	79	115

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtllvsGsdDgtikvWDlrtgv 34
           gHt++v ++a+   +d+ ++sGs D+t++vW++ +g 
   Q: 79   GHTAPVLDIAWcphNDNVIASGSEDCTVMVWEIPDGG 115
           8***********9877****************98886 PP

Organism

Pongo abelii

Protein Sequence
(Fasta)

MSRQVVRSSK FRHVFGQPAK ADQCYEDVRV SQTTWDSGFC AVNPKFVALI CEASGGGAFL 60
VLPLGKTGRV DKNAPTVCGH TAPVLDIAWC PHNDNVIASG SEDCTVMVWE IPDGGLMLPL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGAAAGGCT GGCGAGGAGG CTGGGGGCGG ACGCAGGGAG GAAAGAAGCA ATGGGGTGTT 60
TTTGCGTTTT GACATTTTAA AAAGAAATGC AGATTCGCTT CCCGGAGCCG GGCTGGCAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR029508--CORO1A
IPR015505--Coronin
IPR015048--DUF1899
IPR015049--Trimer_CC
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08953--DUF1899
PF08954--Trimer_CC
PF00400--WD40

SMART

SM01166--DUF1899
SM00320--WD40

Gene Ontology

GO:0005884--C:actin filament
GO:0030424--C:axon
GO:0005911--C:cell-cell junction
GO:0030864--C:cortical actin cytoskeleton
GO:0005829--C:cytosol
GO:0005769--C:early endosome
GO:0070062--C:extracellular exosome
GO:0001772--C:immunological synapse
GO:0030027--C:lamellipodium
GO:0001891--C:phagocytic cup
GO:0045335--C:phagocytic vesicle
GO:0043234--C:protein complex
GO:0003723--F:RNA binding
GO:0007015--P:actin filament organization
GO:0006816--P:calcium ion transport
GO:0031589--P:cell-substrate adhesion
GO:0071353--P:cellular response to interleukin-4
GO:0061502--P:early endosome to recycling endosome transport
GO:0048873--P:homeostasis of number of cells within a tissue
GO:0030595--P:leukocyte chemotaxis
GO:0043320--P:natural killer cell degranulation
GO:0051126--P:negative regulation of actin nucleation
GO:0043524--P:negative regulation of neuron apoptotic process
GO:0031339--P:negative regulation of vesicle fusion
GO:0038180--P:nerve growth factor signaling pathway
GO:0001845--P:phagolysosome assembly
GO:0050918--P:positive chemotaxis
GO:0030335--P:positive regulation of cell migration
GO:0042102--P:positive regulation of T cell proliferation
GO:0008360--P:regulation of cell shape
GO:0051279--P:regulation of release of sequestered calcium ion into cytosol
GO:0043029--P:T cell homeostasis
GO:0032796--P:uropod organization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002012	Ailuropoda melanoleuca	90.89	0.00e+00	851.00
IUUC-Bta-013168	Bos taurus	90.46	0.00e+00	850.00
IUUC-Cja-019660	Callithrix jacchus	92.62	0.00e+00	866.00
IUUC-Cfa-020938	Canis familiaris	91.97	0.00e+00	859.00
IUUC-Cpo-022056	Cavia porcellus	90.24	0.00e+00	851.00
IUUC-Csa-023193	Chlorocebus sabaeus	93.71	0.00e+00	873.00
IUUC-Dno-029363	Dasypus novemcinctus	91.54	0.00e+00	857.00
IUUC-Dor-030426	Dipodomys ordii	90.46	0.00e+00	845.00
IUUC-Eca-034229	Equus caballus	91.11	0.00e+00	853.00
IUUC-Eeu-034499	Erinaceus europaeus	88.40	0.00e+00	719.00
IUUC-Fca-036472	Felis catus	90.24	0.00e+00	845.00
IUUC-Ggo-045162	Gorilla gorilla	94.14	0.00e+00	877.00
IUUC-Hsa-046874	Homo sapiens	94.14	0.00e+00	877.00
IUUC-Itr-048911	Ictidomys tridecemlineatus	91.11	0.00e+00	857.00
IUUC-Laf-053427	Loxodonta africana	91.11	0.00e+00	845.00
IUUC-Mcc-055750	Macaca mulatta	93.44	0.00e+00	806.00
IUUC-Meu-056083	Macropus eugenii	83.30	0.00e+00	784.00
IUUC-Mmr-060858	Microcebus murinus	91.76	0.00e+00	860.00
IUUC-Mdo-062469	Monodelphis domestica	85.15	0.00e+00	788.00
IUUC-Mmu-063583	Mus musculus	89.37	0.00e+00	842.00
IUUC-Mpu-066451	Mustela putorius furo	90.50	0.00e+00	816.00
IUUC-Mlu-066978	Myotis lucifugus	90.24	0.00e+00	847.00
IUUC-Nle-069815	Nomascus leucogenys	93.93	0.00e+00	875.00
IUUC-Opr-070911	Ochotona princeps	88.07	0.00e+00	821.00
IUUC-Ocu-074429	Oryctolagus cuniculus	80.04	0.00e+00	717.00
IUUC-Oga-089072	Otolemur garnettii	89.42	0.00e+00	839.00
IUUC-Oar-089676	Ovis aries	90.67	0.00e+00	852.00
IUUC-Ptr-091647	Pan troglodytes	93.93	0.00e+00	875.00
IUUC-Pan-092672	Papio anubis	93.71	0.00e+00	873.00
IUUC-Pva-102668	Pteropus vampyrus	90.67	0.00e+00	849.00
IUUC-Rno-105604	Rattus norvegicus	88.72	0.00e+00	833.00
IUUC-Sha-107210	Sarcophilus harrisii	84.60	0.00e+00	808.00
IUUC-Sar-113292	Sorex araneus	89.46	0.00e+00	668.00
IUUC-Tbe-128025	Tupaia belangeri	92.19	1.00e-144	504.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence