iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cpo-022147

Ensembl Protein ID

ENSCPOP00000012964.2

UniProt Accession

H0VQX3; H0VQX3_CAVPO

Genbank Protein ID

ENSCPOP00000012964

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02037165

Gene Name

RNF144B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000014390.3	ENSCPOT00000014535.2	ENSCPOP00000012964.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RBR	2.70e-51	174.9	29	221

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RBR

   S: 1    CkvCllelsveeltvlleCehtfCkeClkqylelkikegqvteiscpaaecpek..leeseikellveeelykryekllleevveadaal 88
           Ck+Cl+e+s +++t+l+eC+++fC++Clkqy++l+i+eg+ + i+cp++ c ++  l+e+ei++ lv  ++++ y++l++e++v+ d+++
   Q: 29   CKLCLCEQSLDKMTTLQECQCIFCTACLKQYMQLAIREGCGSPITCPDMVCLNHgtLQEAEIAC-LVPVDQFQLYQRLKFEREVHLDPHR 117
           ***************************************************9988899******.6999********************* PP
   S: 89   kwcpapdCslvvllekea..eklevecekcgkefCveCkeewHeglsCkelkeklakteeekeeaeskelleanskkCpkCkvyiekneg 176
           +wcp +dC++v+ +++++  + + vec++c+ +fC++Ck++wH+++sC++ + +   te   + a   + +ea +k+Cp C+vyie+neg
   Q: 118  TWCPVADCQTVCPVASSDpgQPVLVECPSCHLKFCSCCKDSWHAEVSCRDSQPAILPTE---HGALFGTGTEAPIKQCPVCRVYIERNEG 204
           *************9998877899999****************************99999...99************************** PP
   S: 177  CnhmtCakCkaefCwlC 193
           C++m+C++Ck++fCw+C
   Q: 205  CAQMMCKNCKHTFCWYC 221
           ***************** PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

MGSVGGLYCL TMTENPTPGD LAPAPLITCK LCLCEQSLDK MTTLQECQCI FCTACLKQYM 60
QLAIREGCGS PITCPDMVCL NHGTLQEAEI ACLVPVDQFQ LYQRLKFERE VHLDPHRTWC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGCTCTG TTGGCGGCCT CTACTGTCTC ACCATGACTG AAAACCCAAC ACCTGGAGAC 60
CTGGCTCCTG CCCCCCTCAT CACTTGCAAA CTCTGCTTGT GTGAACAGTC TCTGGACAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR016150--Casein_kin_II_reg-sub_b-sht
IPR031127--E3_UB_ligase_RBR
IPR002867--IBR_dom
IPR001841--Znf_RING
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1

Pfam

PF01485--IBR

SMART

SM00647--IBR
SM00184--RING

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0031966--C:mitochondrial membrane
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001257	Ailuropoda melanoleuca	93.07	3.00e-166	577.00
IUUC-Atr-002709	Amborella trichopoda	27.64	1.00e-16	82.00
IUUC-Apl-004112	Anas platyrhynchos	82.21	6.00e-129	453.00
IUUC-Aca-004533	Anolis carolinensis	76.90	2.00e-136	478.00
IUUC-Ath-007704	Arabidopsis thaliana	29.90	1.00e-13	70.50
IUUC-Bta-012641	Bos taurus	95.07	4.00e-170	590.00
IUUC-Cja-019626	Callithrix jacchus	79.54	1.00e-136	479.00
IUUC-Cfa-020702	Canis familiaris	93.07	2.00e-167	581.00
IUUC-Csa-023473	Chlorocebus sabaeus	94.39	3.00e-169	587.00
IUUC-Cho-024298	Choloepus hoffmanni	90.66	7.00e-138	482.00
IUUC-Dre-028099	Danio rerio	65.79	1.00e-91	329.00
IUUC-Dno-029122	Dasypus novemcinctus	88.49	3.00e-155	540.00
IUUC-Dor-030669	Dipodomys ordii	95.71	1.00e-132	465.00
IUUC-Ete-033141	Echinops telfairi	80.20	1.00e-129	455.00
IUUC-Eca-034360	Equus caballus	95.05	3.00e-169	587.00
IUUC-Eeu-034538	Erinaceus europaeus	73.24	2.00e-85	307.00
IUUC-Fca-036055	Felis catus	93.40	5.00e-168	583.00
IUUC-Fal-037339	Ficedula albicollis	81.00	3.00e-131	461.00
IUUC-Gmo-038780	Gadus morhua	60.44	1.00e-84	306.00
IUUC-Gga-040256	Gallus gallus	79.72	2.00e-130	458.00
IUUC-Gac-042127	Gasterosteus aculeatus	63.21	1.00e-92	332.00
IUUC-Ggo-044867	Gorilla gorilla	96.04	5.00e-171	593.00
IUUC-Hsa-046928	Homo sapiens	95.71	2.00e-170	591.00
IUUC-Hvu-047484	Hordeum vulgare	31.07	3.00e-17	82.80
IUUC-Itr-048250	Ictidomys tridecemlineatus	95.85	6.00e-109	385.00
IUUC-Lch-050168	Latimeria chalumnae	73.77	1.00e-130	458.00
IUUC-Lpe-051649	Leersia perrieri	29.06	3.00e-16	80.90
IUUC-Loc-052150	Lepisosteus oculatus	62.98	7.00e-86	310.00
IUUC-Laf-053967	Loxodonta africana	92.74	4.00e-165	573.00
IUUC-Mcc-055898	Macaca mulatta	94.39	3.00e-169	587.00
IUUC-Meu-056628	Macropus eugenii	94.87	5.00e-42	164.00
IUUC-Mtr-057989	Medicago truncatula	26.76	7.00e-20	90.90
IUUC-Mga-059820	Meleagris gallopavo	79.00	2.00e-129	454.00
IUUC-Mmr-060680	Microcebus murinus	93.07	2.00e-166	578.00
IUUC-Mdo-062839	Monodelphis domestica	85.20	3.00e-151	527.00
IUUC-Mmu-063339	Mus musculus	88.45	6.00e-149	519.00
IUUC-Mac-065414	Musa acuminata	28.91	8.00e-20	90.90
IUUC-Mpu-065973	Mustela putorius furo	91.75	9.00e-165	572.00
IUUC-Mlu-067112	Myotis lucifugus	93.07	7.00e-158	549.00
IUUC-Nle-069795	Nomascus leucogenys	95.38	8.00e-171	592.00
IUUC-Opr-070390	Ochotona princeps	86.80	4.00e-149	520.00
IUUC-Ont-072329	Oreochromis niloticus	63.95	3.00e-88	318.00
IUUC-Oan-072980	Ornithorhynchus anatinus	82.97	7.00e-136	476.00
IUUC-Ocu-073845	Oryctolagus cuniculus	93.40	2.00e-167	580.00
IUUC-Ola-086872	Oryzias latipes	61.42	7.00e-84	303.00
IUUC-Oga-088954	Otolemur garnettii	93.07	2.00e-165	574.00
IUUC-Oar-089879	Ovis aries	95.07	4.00e-170	590.00
IUUC-Ptr-090685	Pan troglodytes	95.71	2.00e-170	591.00
IUUC-Pan-092086	Papio anubis	94.06	4.00e-169	586.00
IUUC-Psi-093481	Pelodiscus sinensis	81.19	3.00e-136	477.00
IUUC-Pfo-096065	Poecilia formosa	64.77	6.00e-91	327.00
IUUC-Pab-098031	Pongo abelii	95.38	3.00e-170	590.00
IUUC-Pop-099816	Populus trichocarpa	27.23	7.00e-15	75.10
IUUC-Pca-100936	Procavia capensis	91.09	2.00e-161	561.00
IUUC-Pva-102864	Pteropus vampyrus	83.83	5.00e-144	503.00
IUUC-Rno-105503	Rattus norvegicus	88.45	1.00e-148	518.00
IUUC-Sha-107425	Sarcophilus harrisii	85.20	2.00e-151	527.00
IUUC-Stu-112736	Solanum tuberosum	27.83	2.00e-18	85.90
IUUC-Ssc-115458	Sus scrofa	92.51	5.00e-156	543.00
IUUC-Tgu-117226	Taeniopygia guttata	79.93	5.00e-131	460.00
IUUC-Tru-118362	Takifugu rubripes	63.53	7.00e-92	330.00
IUUC-Tsy-119255	Tarsius syrichta	95.05	6.00e-171	592.00
IUUC-Tni-120140	Tetraodon nigroviridis	61.37	9.00e-88	316.00
IUUC-Tae-124420	Triticum aestivum	32.16	5.00e-18	85.90
IUUC-Tbe-127306	Tupaia belangeri	94.06	1.00e-167	582.00
IUUC-Ttr-128923	Tursiops truncatus	93.42	5.00e-157	546.00
IUUC-Vpa-130148	Vicugna pacos	93.73	4.00e-167	580.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence