iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pan-092853

Ensembl Protein ID

ENSPANP00000020032.1

UniProt Accession

A0A096P3V7; A0A096P3V7_PAPAN

Genbank Protein ID

ENSPANP00000020032

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHZZ01046604

Gene Name

RFFL

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPANG00000023003.1	ENSPANT00000020905.1	ENSPANP00000020032.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	97.80	0.00e+00	740.00	IUUC-Hsa-045798

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Papio anubis

Protein Sequence
(Fasta)

MWATCCNWFC LDGQPEEVPP PQGARMQAYS NPGYSSFPSP TGLEPSCKSC GAHFARTNQQ 60
QTCLDCKKNF CMTCSSQVGN GPRLCLLCQR FRATAFQREE LMKMKVKDLR DYLSLHDIST 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTGGGCAA CCTGCTGCAA CTGGTTCTGC CTGGATGGAC AGCCTGAAGA GGTCCCACCA 60
CCCCAGGGAG CCAGGATGCA GGCCTATTCC AACCCTGGGT ACAGCTCCTT CCCTTCCCCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001370--BIR_rpt
IPR003034--SAP_dom
IPR011011--Znf_FYVE_PHD
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

SMART

SM00184--RING

Gene Ontology

GO:0010008--C:endosome membrane
GO:0005886--C:plasma membrane
GO:0002947--C:tumor necrosis factor receptor superfamily complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:2001271--P:negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis
GO:1902042--P:negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:1901797--P:negative regulation of signal transduction by p53 class mediator
GO:0010804--P:negative regulation of tumor necrosis factor-mediated signaling pathway
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0070936--P:protein K48-linked ubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001630	Ailuropoda melanoleuca	89.53	0.00e+00	631.00
IUUC-Apl-004124	Anas platyrhynchos	64.93	4.00e-122	431.00
IUUC-Aly-005548	Arabidopsis lyrata	47.06	1.00e-08	55.50
IUUC-Ame-011616	Astyanax mexicanus	58.58	2.00e-102	365.00
IUUC-Bta-012374	Bos taurus	85.40	0.00e+00	631.00
IUUC-Cja-019780	Callithrix jacchus	94.78	0.00e+00	683.00
IUUC-Cfa-021252	Canis familiaris	91.46	0.00e+00	641.00
IUUC-Cpo-022047	Cavia porcellus	90.63	0.00e+00	659.00
IUUC-Csa-023161	Chlorocebus sabaeus	98.62	0.00e+00	744.00
IUUC-Cho-024316	Choloepus hoffmanni	91.42	1.00e-157	548.00
IUUC-Cne-026858	Cryptococcus neoformans	25.15	7.00e-07	48.50
IUUC-Dre-028596	Danio rerio	55.37	1.00e-108	386.00
IUUC-Dno-029333	Dasypus novemcinctus	91.18	0.00e+00	660.00
IUUC-Ete-033163	Echinops telfairi	82.64	1.00e-163	569.00
IUUC-Eca-033994	Equus caballus	91.46	0.00e+00	672.00
IUUC-Eeu-035162	Erinaceus europaeus	87.67	2.00e-133	468.00
IUUC-Fca-036418	Felis catus	90.36	0.00e+00	688.00
IUUC-Fal-037427	Ficedula albicollis	64.85	2.00e-131	461.00
IUUC-Gga-041053	Gallus gallus	66.94	1.00e-129	455.00
IUUC-Ggo-045436	Gorilla gorilla	97.80	0.00e+00	740.00
IUUC-Hsa-045798	Homo sapiens	97.80	0.00e+00	740.00
IUUC-Itr-048077	Ictidomys tridecemlineatus	90.91	0.00e+00	643.00
IUUC-Lch-050639	Latimeria chalumnae	61.71	1.00e-124	439.00
IUUC-Laf-053355	Loxodonta africana	87.70	3.00e-177	613.00
IUUC-Mcc-055222	Macaca mulatta	98.07	0.00e+00	688.00
IUUC-Meu-056692	Macropus eugenii	77.13	6.00e-158	550.00
IUUC-Mga-059298	Meleagris gallopavo	65.84	2.00e-128	452.00
IUUC-Mmr-061792	Microcebus murinus	89.81	0.00e+00	639.00
IUUC-Mdo-062986	Monodelphis domestica	80.72	3.00e-169	587.00
IUUC-Mmu-063356	Mus musculus	87.88	0.00e+00	639.00
IUUC-Mpu-066273	Mustela putorius furo	90.63	0.00e+00	688.00
IUUC-Mlu-066953	Myotis lucifugus	90.36	0.00e+00	674.00
IUUC-Nle-070075	Nomascus leucogenys	97.52	0.00e+00	736.00
IUUC-Opr-070838	Ochotona princeps	88.71	0.00e+00	636.00
IUUC-Ont-071967	Oreochromis niloticus	50.41	6.00e-90	323.00
IUUC-Ocu-074807	Oryctolagus cuniculus	90.08	0.00e+00	675.00
IUUC-Obr-076159	Oryza brachyantha	41.07	4.00e-08	50.40
IUUC-Ola-086903	Oryzias latipes	68.21	8.00e-56	210.00
IUUC-Oga-088536	Otolemur garnettii	89.53	9.00e-179	619.00
IUUC-Oar-089838	Ovis aries	85.95	2.00e-178	617.00
IUUC-Ptr-090962	Pan troglodytes	97.52	0.00e+00	739.00
IUUC-Psi-093164	Pelodiscus sinensis	64.11	6.00e-124	436.00
IUUC-Pma-094104	Petromyzon marinus	44.65	3.00e-57	215.00
IUUC-Pno-094968	Phaeosphaeria nodorum	36.73	2.00e-08	56.20
IUUC-Pab-098304	Pongo abelii	98.35	0.00e+00	740.00
IUUC-Pca-100316	Procavia capensis	88.71	2.00e-176	611.00
IUUC-Ppe-101490	Prunus persica	37.80	1.00e-09	57.80
IUUC-Pva-102612	Pteropus vampyrus	76.86	1.00e-156	545.00
IUUC-Rno-105449	Rattus norvegicus	88.71	0.00e+00	638.00
IUUC-Sha-107578	Sarcophilus harrisii	79.61	2.00e-156	545.00
IUUC-Sar-113638	Sorex araneus	85.40	5.00e-174	603.00
IUUC-Ssc-116401	Sus scrofa	89.81	0.00e+00	681.00
IUUC-Tru-118765	Takifugu rubripes	49.32	2.00e-82	298.00
IUUC-Tsy-118850	Tarsius syrichta	90.10	4.00e-154	536.00
IUUC-Tbe-128086	Tupaia belangeri	83.75	2.00e-179	620.00
IUUC-Ttr-128249	Tursiops truncatus	69.15	1.00e-139	489.00
IUUC-Vpa-130816	Vicugna pacos	87.21	6.00e-41	160.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence