iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000001085.3	ENSCPOT00000022411.1	ENSCPOP00000015687.1
ENSCPOG00000001085.3	ENSCPOT00000001096.2	ENSCPOP00000000981.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	2.20e-07	31.3	351	390

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C iC e+ kd +++ pCgH+ + +Cl +w     + + +++CP Cr
   Q: 351  CKICAERDKD-VRIEPCGHLLCSHCLAAW-----QHKDSQTCPFCR 390
           99********.******************.....6789999****8 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

MAAAAGPRGG QWAEQRALGR AVRLLQSLEE QCGDPRLAMG PPSLRDLLPS TVRLLRAVAR 60
VRHDAGPGGS EGPGGAWNFL QVFLANLEAK AKQVAGLLPG RGRRGASDDL FLEGSRLRQQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTACCCACAA GATCCCCCAG TTCTGGCCTA GTCTGACCAC CACAGGGACT TTAGGACAGC 60
CCCCGGGAGG ACCAGGAAGC CACTGGTCTC AGAGGCTTCC TTTTCAGCTG TTTAGGAGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR024162--Adaptor_Cbl
IPR014741--Adaptor_Cbl_EF_hand-like
IPR003153--Adaptor_Cbl_N_hlx
IPR014742--Adaptor_Cbl_SH2-like
IPR024159--Cbl_PTB
IPR011992--EF-hand-dom_pair
IPR000980--SH2
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51506--CBL_PTB
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF02262--Cbl_N
PF02761--Cbl_N2
PF02762--Cbl_N3

SMART

SM00184--RING

Gene Ontology

GO:0005634--C:nucleus
GO:0005509--F:calcium ion binding
GO:0004871--F:signal transducer activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007166--P:cell surface receptor signaling pathway
GO:0023051--P:regulation of signaling

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002286	Ailuropoda melanoleuca	78.30	9.00e-166	576.00
IUUC-Bta-012705	Bos taurus	74.11	1.00e-172	599.00
IUUC-Cja-019179	Callithrix jacchus	75.76	0.00e+00	635.00
IUUC-Cfa-020593	Canis familiaris	76.47	7.00e-164	570.00
IUUC-Csa-023966	Chlorocebus sabaeus	76.50	6.00e-169	587.00
IUUC-Dor-030246	Dipodomys ordii	74.34	2.00e-118	419.00
IUUC-Eca-033921	Equus caballus	69.75	2.00e-137	482.00
IUUC-Fca-035747	Felis catus	62.35	1.00e-141	496.00
IUUC-Ggo-044622	Gorilla gorilla	80.07	4.00e-145	507.00
IUUC-Hsa-045735	Homo sapiens	76.36	0.00e+00	630.00
IUUC-Itr-049001	Ictidomys tridecemlineatus	79.42	1.00e-155	542.00
IUUC-Laf-053983	Loxodonta africana	70.70	8.00e-177	613.00
IUUC-Mmr-061310	Microcebus murinus	75.86	1.00e-174	605.00
IUUC-Mmu-064155	Mus musculus	71.63	3.00e-172	598.00
IUUC-Mpu-066655	Mustela putorius furo	75.84	2.00e-174	605.00
IUUC-Mlu-067929	Myotis lucifugus	76.82	2.00e-135	474.00
IUUC-Nle-070065	Nomascus leucogenys	63.83	6.00e-141	493.00
IUUC-Ocu-074049	Oryctolagus cuniculus	73.70	5.00e-123	434.00
IUUC-Oga-087952	Otolemur garnettii	77.22	0.00e+00	643.00
IUUC-Oar-089382	Ovis aries	75.43	5.00e-167	580.00
IUUC-Pan-092075	Papio anubis	76.26	1.00e-168	586.00
IUUC-Pab-098100	Pongo abelii	67.38	2.00e-152	531.00
IUUC-Pca-100830	Procavia capensis	73.12	1.00e-101	363.00
IUUC-Pva-102714	Pteropus vampyrus	71.69	8.00e-150	523.00
IUUC-Pgr-103631	Puccinia graminis	35.94	1.00e-06	46.60
IUUC-Rno-105348	Rattus norvegicus	74.34	2.00e-177	615.00
IUUC-Sha-107138	Sarcophilus harrisii	65.42	3.00e-116	411.00
IUUC-Ssc-116424	Sus scrofa	71.96	8.00e-178	616.00
IUUC-Ttr-128807	Tursiops truncatus	78.93	2.00e-124	438.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence