iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-090065

Ensembl Protein ID

ENSOARP00000012667.1

UniProt Accession

W5PQE0; W5PQE0_SHEEP

Genbank Protein ID

ENSOARP00000012667

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01012101

Gene Name

AIRE

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000011819.1	ENSOART00000012853.1	ENSOARP00000012667.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/PHD	77.14	4.00e-145	512.00	IUUC-Hsa-046603

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ovis aries

Protein Sequence
(Fasta)

MAGEARAGGD AALRRLLRLH RTEIAVAVDS AFPLLHALAD HDVVPEDKFQ ETLRLKEKEG 60
CPQAFHALLS WLLTQDAGAI LDFWRVLFKD YNLERYVRLQ SILDTFPKDV DLSQSRKGRR 120

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Nucleotide Sequence
(Fasta)

ATGGCGGGCG AGGCCCGGGC CGGTGGGGAC GCGGCGCTGC GCCGCCTGCT GAGGCTGCAT 60
CGCACGGAGA TCGCGGTGGC CGTGGACAGC GCCTTCCCGC TGCTGCACGC GCTGGCCGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR008087--AIRE
IPR004865--HSR_dom
IPR000770--SAND_dom
IPR010919--SAND_dom-like
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51414--HSR
PS50864--SAND
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF03172--HSR
PF00628--PHD
PF01342--SAND

PRINTS

PR01711--AIREGULATOR

SMART

SM00249--PHD
SM00258--SAND

Gene Ontology

GO:0005737--C:cytoplasm
GO:0016604--C:nuclear body
GO:0003682--F:chromatin binding
GO:0000977--F:RNA polymerase II regulatory region sequence-specific DNA binding
GO:0045182--F:translation regulator activity
GO:0008270--F:zinc ion binding
GO:0002509--P:central tolerance induction to self antigen
GO:0032602--P:chemokine production
GO:0006959--P:humoral immune response
GO:0045060--P:negative thymic T cell selection
GO:0002458--P:peripheral T cell tolerance induction
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:2000410--P:regulation of thymocyte migration
GO:0097536--P:thymus epithelium morphogenesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001612	Ailuropoda melanoleuca	80.32	6.00e-162	563.00
IUUC-Aca-004543	Anolis carolinensis	66.13	1.00e-23	100.00
IUUC-Bta-012988	Bos taurus	94.38	0.00e+00	722.00
IUUC-Bci-013636	Botrytis cinerea	46.00	7.00e-10	60.10
IUUC-Bdi-014663	Brachypodium distachyon	57.45	4.00e-13	71.20
IUUC-Cja-019486	Callithrix jacchus	66.20	9.00e-50	190.00
IUUC-Cfa-021069	Canis familiaris	80.37	2.00e-156	545.00
IUUC-Cpo-021649	Cavia porcellus	69.35	9.00e-132	463.00
IUUC-Csa-023960	Chlorocebus sabaeus	79.57	5.00e-141	494.00
IUUC-Cne-026966	Cryptococcus neoformans	56.86	6.00e-12	65.50
IUUC-Dre-028583	Danio rerio	39.33	5.00e-57	215.00
IUUC-Dno-029869	Dasypus novemcinctus	66.67	2.00e-110	392.00
IUUC-Dor-030263	Dipodomys ordii	86.02	1.00e-45	176.00
IUUC-Dse-031258	Dothistroma septosporum	40.30	2.00e-10	61.60
IUUC-Ete-032778	Echinops telfairi	90.91	4.00e-49	189.00
IUUC-Eca-034328	Equus caballus	82.50	2.00e-161	562.00
IUUC-Fca-035400	Felis catus	78.70	8.00e-170	590.00
IUUC-Fal-036644	Ficedula albicollis	50.56	1.00e-74	274.00
IUUC-Fox-038014	Fusarium oxysporum	40.43	3.00e-09	57.80
IUUC-Fso-038262	Fusarium solani	42.55	3.00e-09	58.20
IUUC-Ggo-045250	Gorilla gorilla	78.86	1.00e-133	469.00
IUUC-Hsa-046603	Homo sapiens	78.98	2.00e-133	469.00
IUUC-Hvu-047073	Hordeum vulgare	58.70	1.00e-13	72.80
IUUC-Itr-048977	Ictidomys tridecemlineatus	71.14	2.00e-131	462.00
IUUC-Lch-050310	Latimeria chalumnae	47.99	1.00e-86	313.00
IUUC-Loc-052508	Lepisosteus oculatus	48.19	3.00e-80	292.00
IUUC-Lma-053053	Leptosphaeria maculans	35.14	1.00e-15	79.30
IUUC-Laf-054028	Loxodonta africana	76.33	1.00e-141	496.00
IUUC-Mcc-054935	Macaca mulatta	79.81	2.00e-146	512.00
IUUC-Mga-059318	Meleagris gallopavo	42.07	7.00e-55	207.00
IUUC-Mmr-061557	Microcebus murinus	63.40	1.00e-113	403.00
IUUC-Mdo-062475	Monodelphis domestica	54.55	2.00e-99	356.00
IUUC-Mmu-063994	Mus musculus	73.68	5.00e-159	554.00
IUUC-Mac-065614	Musa acuminata	43.94	4.00e-12	67.40
IUUC-Mpu-066347	Mustela putorius furo	78.73	8.00e-166	576.00
IUUC-Mlu-068239	Myotis lucifugus	72.87	4.00e-54	204.00
IUUC-Nle-069544	Nomascus leucogenys	76.19	2.00e-25	109.00
IUUC-Opr-071199	Ochotona princeps	74.70	1.00e-73	270.00
IUUC-Ont-072571	Oreochromis niloticus	33.14	3.00e-36	146.00
IUUC-Oan-073739	Ornithorhynchus anatinus	59.35	4.00e-123	434.00
IUUC-Ogl-077865	Oryza glaberrima	54.35	4.00e-12	67.40
IUUC-Ola-086528	Oryzias latipes	33.33	6.00e-40	158.00
IUUC-Oga-088353	Otolemur garnettii	75.53	7.00e-166	577.00
IUUC-Ptr-091347	Pan troglodytes	75.53	2.00e-127	449.00
IUUC-Pan-092423	Papio anubis	77.16	2.00e-138	485.00
IUUC-Psi-093798	Pelodiscus sinensis	55.73	2.00e-102	365.00
IUUC-Pfo-096145	Poecilia formosa	72.92	4.00e-20	92.40
IUUC-Pab-098369	Pongo abelii	79.76	4.00e-127	447.00
IUUC-Pca-100537	Procavia capensis	73.52	7.00e-147	513.00
IUUC-Ppe-101215	Prunus persica	60.42	2.00e-14	74.70
IUUC-Pva-102639	Pteropus vampyrus	79.19	2.00e-155	542.00
IUUC-Pte-104185	Pyrenophora teres	40.54	9.00e-14	73.60
IUUC-Pyt-104775	Pyrenophora triticirepentis	38.55	9.00e-14	72.80
IUUC-Rno-105285	Rattus norvegicus	71.66	2.00e-157	549.00
IUUC-Sha-107159	Sarcophilus harrisii	52.87	2.00e-99	356.00
IUUC-Sja-107964	Schizosaccharomyces japonicus	30.84	6.00e-12	65.50
IUUC-Sit-110355	Setaria italica	54.17	1.00e-12	68.90
IUUC-Sbi-113930	Sorghum bicolor	54.17	1.00e-12	69.30
IUUC-Ssc-115773	Sus scrofa	78.33	7.00e-162	563.00
IUUC-Tgu-116922	Taeniopygia guttata	50.29	1.00e-72	266.00
IUUC-Tru-118263	Takifugu rubripes	32.95	1.00e-40	160.00
IUUC-Tsy-119270	Tarsius syrichta	69.43	2.00e-90	326.00
IUUC-Tni-120138	Tetraodon nigroviridis	32.87	1.00e-46	181.00
IUUC-Tca-121757	Theobroma cacao	54.72	8.00e-14	73.60
IUUC-Tae-124715	Triticum aestivum	58.70	1.00e-13	72.80
IUUC-Tur-126422	Triticum urartu	55.32	3.00e-12	68.60
IUUC-Tme-127204	Tuber melanosporum	55.32	6.00e-14	73.20
IUUC-Tbe-128077	Tupaia belangeri	71.06	2.00e-153	535.00
IUUC-Ttr-128781	Tursiops truncatus	87.70	3.00e-89	322.00
IUUC-Xma-133054	Xiphophorus maculatus	33.13	3.00e-43	169.00
IUUC-Yli-134436	Yarrowia lipolytica	39.74	3.00e-11	63.50

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence