iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Sit-110801

Ensembl Protein ID

Si030510m

UniProt Accession

K3ZV79; K3ZV79_SETIT

Genbank Protein ID

KQL22553.1

Protein Name

Eukaryotic translation initiation factor 3 subunit I

Genbank Nucleotide ID

CM003529

Gene Name

LOC101760206; SETIT_030510mg

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Si030510m.g	Si030510m	Si030510m

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	7.30e-24	83.8	50	87
UBD/Beta-Prp	5.60e-41	141.6	6	255

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           gH++ v++++   d  +l++Gs D t k+WD++tg+ l
   Q: 50   GHNGAVWSCDVsRDsARLITGSADQTAKLWDVSTGREL 87
           8**********977799*****************9976 PP

UBD/Beta-Prp

   S: 48   lsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee................ 131
           ++ghe + t +++++dg++l ++++D+t  vw  ++g+ + t++gh+  v+s+++s+++ +l++Gs+d+t+++wd++tg +l +                
   Q: 6    MKGHERPLTFLRYNRDGDLLFSCAKDHTPTVWYADNGDRLGTYRGHNGAVWSCDVSRDSARLITGSADQTAKLWDVSTGRELFSfrfdaparsvefaigd 105
           4789999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999 PP
   S: 132  ...................................tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl..tgghtdsvyslsfdsngke 194
                                              + +g +g +n +v+ p ++ +++++ D t+r+Wd +tgkll++   ++gh++ + sls + +  +
   Q: 106  alavittdnfmdhvptvqvkhiaedlddqtdesalVITGIKGRINRAVWGPLNRTIITAGEDATIRIWDTETGKLLKESdkESGHQKTISSLSKSADWSH 205
           99999999999999999999999999999999999*********************************************9777**************** PP
   S: 195  lvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgs.sDg 244
           +++gsld++ klwd +t + ++t+   +++v+ v+ sp ++ +v g+ +D 
   Q: 206  FITGSLDKSAKLWDSRTLTLIKTYVT-ERPVNAVDISPTHDTVVLGGgQDA 255
           ***********************996.568999999977777777763443 PP

Organism

Setaria italica

Functional Description
(View)

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

Protein Sequence
(Fasta)

MRPILMKGHE RPLTFLRYNR DGDLLFSCAK DHTPTVWYAD NGDRLGTYRG HNGAVWSCDV 60
SRDSARLITG SADQTAKLWD VSTGRELFSF RFDAPARSVE FAIGDALAVI TTDNFMDHVP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGTTTTCTCG TCTCCGCCGC CGACGCATCC AAATCAAACC CTTCCCCATC CACCACCCTC 60
CCCACTTCCG GCGGCGGCGA GCGGCGGCAC CACCACCACC ACGCCACGAT GAGGCCGATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0396--Initiation factor
KW-0648--Protein biosynthesis
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR027525--eIF3i
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0016282--C:eukaryotic 43S preinitiation complex
GO:0033290--C:eukaryotic 48S preinitiation complex
GO:0005852--C:eukaryotic translation initiation factor 3 complex
GO:0003743--F:translation initiation factor activity
GO:0001731--P:formation of translation preinitiation complex
GO:0006446--P:regulation of translational initiation

KEGG

sita:101760206

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000115	Aegilops tauschii	50.00	3.00e-65	241.00
IUUC-Aml-001321	Ailuropoda melanoleuca	45.54	5.00e-85	306.00
IUUC-Atr-002468	Amborella trichopoda	71.60	1.00e-97	347.00
IUUC-Apl-003841	Anas platyrhynchos	45.85	9.00e-85	306.00
IUUC-Aca-005123	Anolis carolinensis	45.71	3.00e-86	311.00
IUUC-Aly-005473	Arabidopsis lyrata	77.13	1.00e-151	528.00
IUUC-Ath-007094	Arabidopsis thaliana	75.61	5.00e-149	519.00
IUUC-Ago-008000	Ashbya gossypii	43.11	6.00e-74	270.00
IUUC-Acl-008098	Aspergillus clavatus	46.22	8.00e-83	299.00
IUUC-Afl-008494	Aspergillus flavus	47.38	1.00e-85	308.00
IUUC-Afu-009080	Aspergillus fumigatus	45.92	5.00e-82	296.00
IUUC-Ani-009230	Aspergillus nidulans	46.79	1.00e-83	302.00
IUUC-Aor-010114	Aspergillus oryzae	47.38	1.00e-85	308.00
IUUC-Ate-010285	Aspergillus terreus	46.48	1.00e-83	302.00
IUUC-Ame-011534	Astyanax mexicanus	45.12	6.00e-86	309.00
IUUC-Bgr-012121	Blumeria graminis	43.21	2.00e-76	278.00
IUUC-Bta-013143	Bos taurus	45.71	1.00e-85	309.00
IUUC-Bci-013950	Botrytis cinerea	46.77	2.00e-85	308.00
IUUC-Bdi-015019	Brachypodium distachyon	88.04	7.00e-174	602.00
IUUC-Bol-015709	Brassica oleracea	77.88	4.00e-153	534.00
IUUC-Bra-017760	Brassica rapa	77.88	2.00e-154	538.00
IUUC-Cel-018226	Caenorhabditis elegans	40.06	1.00e-71	262.00
IUUC-Cja-019741	Callithrix jacchus	45.71	9.00e-86	309.00
IUUC-Cfa-021204	Canis familiaris	45.54	5.00e-85	306.00
IUUC-Cpo-021661	Cavia porcellus	45.23	7.00e-85	306.00
IUUC-Cre-022952	Chlamydomonas reinhardtii	52.45	2.00e-102	365.00
IUUC-Csa-024038	Chlorocebus sabaeus	45.71	9.00e-86	309.00
IUUC-Cin-025597	Ciona intestinalis	47.85	6.00e-89	320.00
IUUC-Cgl-026583	Colletotrichum gloeosporioides	44.65	6.00e-80	290.00
IUUC-Cne-026838	Cryptococcus neoformans	42.90	1.00e-77	282.00
IUUC-Cme-027304	Cyanidioschyzon merolae	51.23	2.00e-86	311.00
IUUC-Dre-028567	Danio rerio	45.09	2.00e-86	311.00
IUUC-Dno-029171	Dasypus novemcinctus	45.54	1.00e-84	306.00
IUUC-Dor-030257	Dipodomys ordii	32.39	5.00e-26	110.00
IUUC-Dse-031191	Dothistroma septosporum	44.07	3.00e-79	288.00
IUUC-Dme-031879	Drosophila melanogaster	48.62	1.00e-88	318.00
IUUC-Ete-032336	Echinops telfairi	38.25	6.00e-42	162.00
IUUC-Eca-033259	Equus caballus	45.54	7.00e-85	306.00
IUUC-Eeu-035153	Erinaceus europaeus	43.07	5.00e-26	110.00
IUUC-Fca-036489	Felis catus	45.54	7.00e-85	306.00
IUUC-Fal-037485	Ficedula albicollis	45.40	2.00e-84	305.00
IUUC-Fox-037860	Fusarium oxysporum	46.46	3.00e-83	301.00
IUUC-Fso-038188	Fusarium solani	45.54	3.00e-79	288.00
IUUC-Gmo-039311	Gadus morhua	44.92	4.00e-84	303.00
IUUC-Ggr-040045	Gaeumannomyces graminis	46.15	4.00e-83	300.00
IUUC-Gga-040645	Gallus gallus	44.91	3.00e-83	301.00
IUUC-Gac-042086	Gasterosteus aculeatus	45.09	3.00e-84	304.00
IUUC-Gma-043246	Glycine max	81.60	3.00e-161	560.00
IUUC-Ggo-045578	Gorilla gorilla	45.71	9.00e-86	309.00
IUUC-Hsa-046734	Homo sapiens	45.71	9.00e-86	309.00
IUUC-Hvu-047553	Hordeum vulgare	89.88	1.00e-176	611.00
IUUC-Itr-048467	Ictidomys tridecemlineatus	45.54	9.00e-85	305.00
IUUC-Kpa-049325	Komagataella pastoris	44.95	2.00e-79	288.00
IUUC-Lch-049620	Latimeria chalumnae	46.18	1.00e-77	282.00
IUUC-Lpe-051338	Leersia perrieri	87.78	1.00e-165	575.00
IUUC-Loc-052094	Lepisosteus oculatus	40.92	2.00e-71	261.00
IUUC-Lma-053047	Leptosphaeria maculans	47.08	3.00e-84	304.00
IUUC-Laf-053801	Loxodonta africana	45.45	3.00e-82	298.00
IUUC-Mcc-055498	Macaca mulatta	40.49	2.00e-67	248.00
IUUC-Meu-056729	Macropus eugenii	41.90	2.00e-75	275.00
IUUC-Mor-057025	Magnaporthe oryzae	45.85	2.00e-80	291.00
IUUC-Mpo-057511	Magnaporthe poae	47.85	1.00e-83	302.00
IUUC-Mtr-058051	Medicago truncatula	80.98	5.00e-160	556.00
IUUC-Mla-059061	Melampsora laricipopulina	43.87	1.00e-80	292.00
IUUC-Mga-059229	Meleagris gallopavo	45.26	3.00e-82	297.00
IUUC-Mvi-060399	Microbotryum violaceum	42.86	2.00e-74	272.00
IUUC-Mmr-060764	Microcebus murinus	45.71	4.00e-86	310.00
IUUC-Mdo-062088	Monodelphis domestica	45.09	2.00e-84	304.00
IUUC-Mmu-064304	Mus musculus	45.40	9.00e-86	309.00
IUUC-Mac-065520	Musa acuminata	80.06	4.00e-158	549.00
IUUC-Mpu-066340	Mustela putorius furo	45.54	7.00e-85	306.00
IUUC-Mlu-067111	Myotis lucifugus	45.40	4.00e-85	307.00
IUUC-Nfi-068478	Neosartorya fischeri	46.22	7.00e-83	299.00
IUUC-Ncr-068820	Neurospora crassa	47.08	6.00e-83	300.00
IUUC-Nle-069903	Nomascus leucogenys	45.54	4.00e-85	307.00
IUUC-Opr-070221	Ochotona princeps	44.17	1.00e-82	299.00
IUUC-Ont-071765	Oreochromis niloticus	45.71	4.00e-87	313.00
IUUC-Oan-073660	Ornithorhynchus anatinus	43.84	3.00e-71	260.00
IUUC-Ocu-074039	Oryctolagus cuniculus	45.54	5.00e-85	306.00
IUUC-Oba-075395	Oryza barthii	83.74	1.00e-159	554.00
IUUC-Obr-076334	Oryza brachyantha	88.04	1.00e-170	591.00
IUUC-Ogl-077751	Oryza glaberrima	92.02	0.00e+00	627.00
IUUC-Ogu-078207	Oryza glumaepatula	90.15	2.00e-176	610.00
IUUC-Oin-079878	Oryza indica	90.49	1.00e-177	614.00
IUUC-Olo-080677	Oryza longistaminata	78.95	8.00e-173	598.00
IUUC-Ome-081228	Oryza meridionalis	70.42	2.00e-91	328.00
IUUC-Oni-082411	Oryza nivara	81.29	1.00e-153	534.00
IUUC-Opu-083136	Oryza punctata	91.72	0.00e+00	625.00
IUUC-Oru-084916	Oryza rufipogon	88.06	4.00e-176	609.00
IUUC-Osa-085776	Oryza sativa	92.02	0.00e+00	627.00
IUUC-Ola-087053	Oryzias latipes	46.01	5.00e-86	310.00
IUUC-Olu-087602	Ostreococcus lucimarinus	60.31	8.00e-117	412.00
IUUC-Oga-088154	Otolemur garnettii	45.85	1.00e-85	308.00
IUUC-Oar-089915	Ovis aries	45.54	5.00e-85	306.00
IUUC-Ptr-091124	Pan troglodytes	36.73	5.00e-57	213.00
IUUC-Pan-092035	Papio anubis	45.71	9.00e-86	309.00
IUUC-Psi-094096	Pelodiscus sinensis	44.04	7.00e-51	192.00
IUUC-Pno-094988	Phaeosphaeria nodorum	43.38	2.00e-73	268.00
IUUC-Ppa-095536	Physcomitrella patens	74.23	1.00e-146	511.00
IUUC-Pfo-096101	Poecilia formosa	44.79	1.00e-85	308.00
IUUC-Pab-097726	Pongo abelii	45.71	9.00e-86	309.00
IUUC-Pop-099617	Populus trichocarpa	78.22	7.00e-155	538.00
IUUC-Pca-101014	Procavia capensis	45.71	6.00e-86	310.00
IUUC-Ppe-101320	Prunus persica	80.98	8.00e-160	555.00
IUUC-Pva-102789	Pteropus vampyrus	42.33	8.00e-75	273.00
IUUC-Pgr-103479	Puccinia graminis	44.48	1.00e-81	295.00
IUUC-Ptt-103981	Puccinia triticina	44.17	3.00e-81	294.00
IUUC-Pte-104278	Pyrenophora teres	45.85	6.00e-81	293.00
IUUC-Pyt-104492	Pyrenophora triticirepentis	45.85	6.00e-81	293.00
IUUC-Rno-105867	Rattus norvegicus	34.67	5.00e-51	194.00
IUUC-Sce-106251	Saccharomyces cerevisiae	41.87	3.00e-74	271.00
IUUC-Sha-107039	Sarcophilus harrisii	44.95	2.00e-84	305.00
IUUC-Sja-107758	Schizosaccharomyces japonicus	44.38	3.00e-82	297.00
IUUC-Spo-108314	Schizosaccharomyces pombe	46.01	2.00e-86	311.00
IUUC-Ssl-108478	Sclerotinia sclerotiorum	46.46	3.00e-85	307.00
IUUC-Smo-108728	Selaginella moellendorffii	71.69	1.00e-140	491.00
IUUC-Sly-111326	Solanum lycopersicum	77.91	8.00e-154	535.00
IUUC-Stu-112458	Solanum tuberosum	79.45	2.00e-155	540.00
IUUC-Sbi-114063	Sorghum bicolor	95.71	0.00e+00	655.00
IUUC-Sre-115096	Sporisorium reilianum	44.18	4.00e-76	277.00
IUUC-Ssc-116080	Sus scrofa	45.71	8.00e-86	309.00
IUUC-Tgu-116988	Taeniopygia guttata	45.54	2.00e-84	305.00
IUUC-Tru-118766	Takifugu rubripes	45.40	8.00e-86	309.00
IUUC-Tni-120197	Tetraodon nigroviridis	45.71	3.00e-86	311.00
IUUC-Tca-121316	Theobroma cacao	81.90	1.00e-160	557.00
IUUC-Tre-122097	Trichoderma reesei	46.48	2.00e-82	298.00
IUUC-Tvi-122442	Trichoderma virens	45.87	2.00e-81	295.00
IUUC-Tae-125800	Triticum aestivum	90.18	3.00e-177	613.00
IUUC-Tur-126334	Triticum urartu	79.75	1.00e-151	528.00
IUUC-Tme-127038	Tuber melanosporum	47.69	5.00e-88	317.00
IUUC-Ttr-128659	Tursiops truncatus	43.56	4.00e-67	247.00
IUUC-Uma-129464	Ustilago maydis	44.18	2.00e-75	274.00
IUUC-Vda-129841	Verticillium dahliae	45.23	1.00e-80	292.00
IUUC-Vvi-131076	Vitis vinifera	80.98	4.00e-161	559.00
IUUC-Xtr-132395	Xenopus tropicalis	47.24	1.00e-87	315.00
IUUC-Xma-133383	Xiphophorus maculatus	44.79	2.00e-85	308.00
IUUC-Yli-134586	Yarrowia lipolytica	44.34	2.00e-70	258.00
IUUC-Zma-135904	Zea mays	96.32	0.00e+00	657.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence