iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-049977

Ensembl Protein ID

ENSLACP00000001025.1

UniProt Accession

H2ZUF4; H2ZUF4_LATCH

Genbank Protein ID

ENSLACP00000001025

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AFYH01261026

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000000916.1	ENSLACT00000001034.1	ENSLACP00000001025.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.30e-06	29.1	32	71
E3 activity/RING/U-box	1.00e-10	41.7	28	96

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlC 45
           C+iC+e f d p++  CgH f+++C+ + w     +++ +++CP+C
   Q: 32   CSICQELFTD-PVIAKCGHNFCRECVcEYW-----EEKMSQSCPIC 71
           **********.999***********98999.....7999999**** PP

E3 activity/RING/U-box

   S: 4    eeflCpIslelMrdPvvlpsGitydrssIekwlasggk.tcPvtrqplteedlvPnltlrrliqawcee 71
           ++  C+I  el++dPv++++G+ + r+++ ++ +++++ +cP++++  + ++l+  +tlr++i+   +e
   Q: 28   DDITCSICQELFTDPVIAKCGHNFCRECVCEYWEEKMSqSCPICGADSAISELITIHTLRNIIETCKKE 96
           5678*************************9999888777************************976555 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

AAKVFKHRGE EAAVCKMDLK RSAGSLEDDI TCSICQELFT DPVIAKCGHN FCRECVCEYW 60
EEKMSQSCPI CGADSAISEL ITIHTLRNII ETCKKESKKS KVQSESICSQ HREELKLYCL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCAGCTAAAG TTTTCAAGCA CAGAGGAGAA GAGGCTGCTG TTTGCAAAAT GGATTTAAAA 60
CGTTCTGCTG GGAGTTTGGA AGATGACATT ACTTGTTCTA TATGTCAGGA ACTGTTTACG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR003613--Ubox_domain
IPR027370--Znf-RING_LisH
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF00643--zf-B_box
PF13445--zf-RING_UBOX

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00589--PRY
SM00184--RING
SM00449--SPRY
SM00504--Ubox

Gene Ontology

GO:0005622--C:intracellular
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Bta-013412	Bos taurus	35.97	1.00e-72	266.00
IUUC-Ete-032949	Echinops telfairi	36.97	2.00e-63	236.00
IUUC-Nle-069798	Nomascus leucogenys	34.85	8.00e-70	257.00
IUUC-Ocu-074797	Oryctolagus cuniculus	36.29	8.00e-70	257.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence