iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ptr-091112

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AACZ03038119

Gene Name

ERCC8

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000016905.3	ENSPTRT00000031347.3	ENSPTRP00000028950.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.90e-30	102.3	199	233
UBD/Beta-Prp	7.70e-46	156.6	69	294

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtllvsGsdDgtikvWDlrt 32
           gH  ++ ++++    d +l+++s D  +k+WD+r+
   Q: 199  GHRQEILAVSWsprYDYILATASADSRVKLWDVRR 233
           8**********96543678*************986 PP

UBD/Beta-Prp

   S: 20   pdksllatgsrdgtikvwdvttgkllrslsgheae..............vtavkfspdgk.ilvtgseDrtikvwdlstgkcvhtlkgh 93
            +++++++g+ dg i ++d+++ +  +s++ ++a               v +v++ p++  ++ ++s D+t+kvwd +t ++  +++  
   Q: 69   VEGRYMLSGGSDGVIVLYDLENSSR-QSYYTCKAVcsigrdhpdvhrysVETVQWYPHDTgMFTSSSFDKTLKVWDTNTLQTADVFN-F 155
           2445555555555555555555444.3333333334444444444444455555544433355555555555555555555555555.5 PP
   S: 94   edsvlslsfsp..sg.dklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgg 178
           e++v+s ++sp  ++   +++G++   +++ dl++g+c++ +l+gh++ +  v+++p    +l+++s+D+ v+lWd+            
   Q: 156  EETVYSHHMSPvsTKhCLVAVGTRGPKVQLCDLKSGSCSH-ILQGHRQEILAVSWSPRYdYILATASADSRVKLWDV------------ 231
           5555555555553222333445555555555555555555.555555555555555555445555555555555555............ PP
   S: 179  htdsvyslsfdsngkelvsgsldgtvklwdlq................tgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdl 251
                                          +                ++ +  + ++h+  v+ + f++++ +l++++ D+  r+W++
   Q: 232  -------------------------------RrasgclitldqhngkkSQAVESANTAHNGKVNGLCFTSDGLHLLTVGTDNRMRLWNS 289
           ...............................5443333333333333222223333444455555555555555555555555555555 PP
   S: 252  rsgdl 256
            +g++
   Q: 290  SNGEN 294
           55444 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MATSSAPAGP RTRYAGVFFR TARRTGLEDP LRLRRAESTR RVLGLELNKD RDVERIHGGG 60
INTLDIEPVE GRYMLSGGSD GVIVLYDLEN SSRQSYYTCK AVCSIGRDHP DVHRYSVETV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCTGTTCCAG TCCCGCCCCT GAGCTCTGTC ATGGCGACGT CCAGTGCTCC AGCCGGGCCG 60
AGGACACGAT ATGCTGGGGT TTTTTTTCGC ACCGCACGCC GAACGGGTTT GGAGGATCCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0031464--C:Cul4A-RING E3 ubiquitin ligase complex
GO:0016363--C:nuclear matrix
GO:0000109--C:nucleotide-excision repair complex
GO:0004842--F:ubiquitin-protein transferase activity
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0051865--P:protein autoubiquitination
GO:0000209--P:protein polyubiquitination
GO:0006979--P:response to oxidative stress
GO:0009411--P:response to UV
GO:0010165--P:response to X-ray
GO:0006283--P:transcription-coupled nucleotide-excision repair

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001170	Aegilops tauschii	30.09	7.00e-37	149.00
IUUC-Aml-002201	Ailuropoda melanoleuca	93.38	0.00e+00	778.00
IUUC-Atr-002784	Amborella trichopoda	37.89	1.00e-40	160.00
IUUC-Apl-003202	Anas platyrhynchos	81.32	0.00e+00	659.00
IUUC-Aca-004708	Anolis carolinensis	79.42	2.00e-173	601.00
IUUC-Aly-006144	Arabidopsis lyrata	30.15	5.00e-44	171.00
IUUC-Ath-006673	Arabidopsis thaliana	39.71	5.00e-45	175.00
IUUC-Acl-008195	Aspergillus clavatus	37.92	9.00e-43	167.00
IUUC-Afl-008406	Aspergillus flavus	36.36	9.00e-39	154.00
IUUC-Afu-008759	Aspergillus fumigatus	35.69	7.00e-40	158.00
IUUC-Ani-009380	Aspergillus nidulans	35.10	6.00e-41	161.00
IUUC-Ang-009820	Aspergillus niger	36.76	5.00e-39	154.00
IUUC-Aor-010092	Aspergillus oryzae	36.67	2.00e-43	170.00
IUUC-Ate-010491	Aspergillus terreus	36.30	2.00e-44	172.00
IUUC-Bta-012825	Bos taurus	93.15	0.00e+00	769.00
IUUC-Bci-013856	Botrytis cinerea	31.58	3.00e-52	199.00
IUUC-Bdi-014899	Brachypodium distachyon	32.84	3.00e-64	239.00
IUUC-Bol-015337	Brassica oleracea	38.50	3.00e-44	172.00
IUUC-Bra-018089	Brassica rapa	38.50	4.00e-44	172.00
IUUC-Cja-018725	Callithrix jacchus	96.18	0.00e+00	793.00
IUUC-Cfa-021162	Canis familiaris	93.64	0.00e+00	778.00
IUUC-Cpo-022190	Cavia porcellus	93.64	0.00e+00	781.00
IUUC-Cre-022960	Chlamydomonas reinhardtii	37.14	3.00e-40	159.00
IUUC-Csa-023610	Chlorocebus sabaeus	99.24	0.00e+00	815.00
IUUC-Cho-024689	Choloepus hoffmanni	92.70	0.00e+00	722.00
IUUC-Cin-025324	Ciona intestinalis	40.11	2.00e-80	292.00
IUUC-Csv-026059	Ciona savignyi	38.14	1.00e-73	270.00
IUUC-Cgl-026384	Colletotrichum gloeosporioides	33.23	8.00e-39	154.00
IUUC-Cme-027182	Cyanidioschyzon merolae	28.66	3.00e-13	70.10
IUUC-Dre-028696	Danio rerio	72.04	3.00e-174	604.00
IUUC-Dno-029102	Dasypus novemcinctus	94.12	0.00e+00	781.00
IUUC-Dor-030361	Dipodomys ordii	76.59	8.00e-177	612.00
IUUC-Dse-031167	Dothistroma septosporum	30.41	5.00e-44	171.00
IUUC-Ete-032856	Echinops telfairi	75.06	2.00e-175	608.00
IUUC-Eca-033611	Equus caballus	95.56	0.00e+00	684.00
IUUC-Eeu-034583	Erinaceus europaeus	71.10	6.00e-159	553.00
IUUC-Fca-036481	Felis catus	93.64	0.00e+00	779.00
IUUC-Fal-037327	Ficedula albicollis	77.94	2.00e-165	574.00
IUUC-Fox-037684	Fusarium oxysporum	30.52	1.00e-43	170.00
IUUC-Fso-038306	Fusarium solani	32.55	4.00e-54	205.00
IUUC-Gmo-039043	Gadus morhua	67.35	1.00e-160	558.00
IUUC-Ggr-039783	Gaeumannomyces graminis	33.67	1.00e-37	150.00
IUUC-Gga-041085	Gallus gallus	84.35	2.00e-179	621.00
IUUC-Gac-042328	Gasterosteus aculeatus	66.58	7.00e-156	543.00
IUUC-Gma-043004	Glycine max	33.75	3.00e-56	212.00
IUUC-Ggo-045627	Gorilla gorilla	90.23	0.00e+00	730.00
IUUC-Hsa-046028	Homo sapiens	99.24	0.00e+00	815.00
IUUC-Hvu-047678	Hordeum vulgare	32.06	2.00e-34	139.00
IUUC-Itr-048648	Ictidomys tridecemlineatus	94.40	0.00e+00	788.00
IUUC-Kpa-049386	Komagataella pastoris	30.33	2.00e-43	170.00
IUUC-Lch-050590	Latimeria chalumnae	78.84	8.00e-160	556.00
IUUC-Lpe-051725	Leersia perrieri	32.80	3.00e-35	142.00
IUUC-Loc-051788	Lepisosteus oculatus	74.23	2.00e-179	621.00
IUUC-Lma-053082	Leptosphaeria maculans	33.71	1.00e-54	206.00
IUUC-Laf-053809	Loxodonta africana	93.91	0.00e+00	780.00
IUUC-Mcc-054998	Macaca mulatta	98.20	2.00e-164	571.00
IUUC-Meu-055929	Macropus eugenii	76.71	1.00e-180	625.00
IUUC-Mor-057003	Magnaporthe oryzae	33.63	3.00e-48	186.00
IUUC-Mtr-057921	Medicago truncatula	32.03	8.00e-57	214.00
IUUC-Mga-059449	Meleagris gallopavo	65.59	7.00e-126	443.00
IUUC-Mmr-061609	Microcebus murinus	91.82	0.00e+00	742.00
IUUC-Mdo-062564	Monodelphis domestica	84.52	0.00e+00	713.00
IUUC-Mmu-063904	Mus musculus	89.09	0.00e+00	744.00
IUUC-Mac-064716	Musa acuminata	36.16	3.00e-40	159.00
IUUC-Mpu-066617	Mustela putorius furo	93.64	0.00e+00	779.00
IUUC-Mlu-067054	Myotis lucifugus	90.84	0.00e+00	758.00
IUUC-Nfi-068467	Neosartorya fischeri	36.51	1.00e-34	140.00
IUUC-Nle-069731	Nomascus leucogenys	99.24	0.00e+00	815.00
IUUC-Opr-070297	Ochotona princeps	67.37	2.00e-84	305.00
IUUC-Ont-072558	Oreochromis niloticus	70.35	1.00e-162	565.00
IUUC-Oan-072864	Ornithorhynchus anatinus	85.96	5.00e-27	111.00
IUUC-Ocu-074415	Oryctolagus cuniculus	94.40	0.00e+00	786.00
IUUC-Oba-075759	Oryza barthii	39.47	5.00e-43	168.00
IUUC-Obr-076387	Oryza brachyantha	37.91	5.00e-45	175.00
IUUC-Ogl-077924	Oryza glaberrima	41.13	2.00e-17	82.00
IUUC-Ogu-078186	Oryza glumaepatula	34.20	8.00e-63	234.00
IUUC-Oin-079389	Oryza indica	33.71	1.00e-46	180.00
IUUC-Olo-080916	Oryza longistaminata	28.43	3.00e-16	78.20
IUUC-Ome-081471	Oryza meridionalis	38.95	2.00e-40	159.00
IUUC-Oni-082449	Oryza nivara	38.95	4.00e-40	159.00
IUUC-Opu-083210	Oryza punctata	38.95	1.00e-42	167.00
IUUC-Oru-085159	Oryza rufipogon	39.47	4.00e-43	168.00
IUUC-Osa-085926	Oryza sativa	39.86	5.00e-33	133.00
IUUC-Ola-087084	Oryzias latipes	67.60	3.00e-164	570.00
IUUC-Olu-087853	Ostreococcus lucimarinus	27.23	2.00e-31	129.00
IUUC-Oga-089008	Otolemur garnettii	92.68	0.00e+00	769.00
IUUC-Oar-089259	Ovis aries	93.65	0.00e+00	771.00
IUUC-Pan-092303	Papio anubis	100.00	5.00e-75	271.00
IUUC-Psi-093050	Pelodiscus sinensis	81.77	0.00e+00	688.00
IUUC-Pma-094259	Petromyzon marinus	55.89	1.00e-125	442.00
IUUC-Pno-094798	Phaeosphaeria nodorum	30.89	7.00e-51	194.00
IUUC-Ppa-095477	Physcomitrella patens	31.18	5.00e-53	201.00
IUUC-Pfo-096855	Poecilia formosa	66.17	5.00e-160	556.00
IUUC-Pab-098096	Pongo abelii	98.47	0.00e+00	810.00
IUUC-Pop-098800	Populus trichocarpa	36.40	4.00e-45	175.00
IUUC-Pca-100187	Procavia capensis	90.64	9.00e-110	390.00
IUUC-Ppe-101759	Prunus persica	36.00	2.00e-43	169.00
IUUC-Pva-102438	Pteropus vampyrus	76.24	6.00e-88	317.00
IUUC-Pte-104197	Pyrenophora teres	33.33	5.00e-50	191.00
IUUC-Pyt-104421	Pyrenophora triticirepentis	33.33	9.00e-50	191.00
IUUC-Rno-106087	Rattus norvegicus	89.85	0.00e+00	751.00
IUUC-Sce-106276	Saccharomyces cerevisiae	26.80	2.00e-12	67.00
IUUC-Sha-106831	Sarcophilus harrisii	82.03	0.00e+00	682.00
IUUC-Sja-107681	Schizosaccharomyces japonicus	32.70	6.00e-56	211.00
IUUC-Spo-108294	Schizosaccharomyces pombe	34.59	6.00e-63	234.00
IUUC-Ssl-108613	Sclerotinia sclerotiorum	32.67	5.00e-52	198.00
IUUC-Smo-109008	Selaginella moellendorffii	40.90	2.00e-76	279.00
IUUC-Sit-110300	Setaria italica	30.43	2.00e-52	199.00
IUUC-Sly-111441	Solanum lycopersicum	28.99	2.00e-43	170.00
IUUC-Stu-111995	Solanum tuberosum	29.27	4.00e-45	175.00
IUUC-Sar-113196	Sorex araneus	84.03	2.00e-130	458.00
IUUC-Sbi-113790	Sorghum bicolor	40.00	2.00e-43	170.00
IUUC-Ssc-115609	Sus scrofa	93.64	0.00e+00	783.00
IUUC-Tgu-116927	Taeniopygia guttata	79.29	0.00e+00	654.00
IUUC-Tru-118164	Takifugu rubripes	69.10	6.00e-170	589.00
IUUC-Tsy-119151	Tarsius syrichta	89.06	0.00e+00	730.00
IUUC-Tni-120896	Tetraodon nigroviridis	68.26	4.00e-160	557.00
IUUC-Tca-121592	Theobroma cacao	29.15	2.00e-44	172.00
IUUC-Tre-122023	Trichoderma reesei	34.73	5.00e-49	188.00
IUUC-Tvi-122507	Trichoderma virens	35.10	5.00e-50	191.00
IUUC-Tae-125730	Triticum aestivum	33.89	4.00e-60	225.00
IUUC-Tur-126092	Triticum urartu	30.29	3.00e-34	139.00
IUUC-Tbe-127422	Tupaia belangeri	71.35	2.00e-152	531.00
IUUC-Ttr-129097	Tursiops truncatus	90.84	0.00e+00	758.00
IUUC-Vda-130014	Verticillium dahliae	36.05	4.00e-51	195.00
IUUC-Vpa-130782	Vicugna pacos	94.16	0.00e+00	781.00
IUUC-Vvi-131494	Vitis vinifera	34.67	3.00e-43	169.00
IUUC-Xtr-132165	Xenopus tropicalis	77.11	6.00e-179	619.00
IUUC-Xma-133205	Xiphophorus maculatus	66.83	1.00e-163	569.00
IUUC-Yli-134614	Yarrowia lipolytica	32.62	1.00e-57	217.00
IUUC-Zma-135861	Zea mays	34.15	2.00e-60	226.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence