iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cfa-020611

Ensembl Protein ID

ENSCAFP00000002118.3

UniProt Accession

F1PH16; F1PH16_CANLF

Genbank Protein ID

ENSCAFP00000002118

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03000522

Gene Name

TLE1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000001462.3	ENSCAFT00000002282.3	ENSCAFP00000002118.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	7.20e-22	76.9	558	596

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gHtd+ +c++  +d t l++G+ D+t++ WDlr+g++l+
   Q: 558  GHTDGASCIDIsNDgTKLWTGGLDNTVRSWDLREGRQLQ 596
           8***********999*********************998 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MQRHYVMYYE MSYGLNIEMH KQTEIAKRLN TICAQVIPFL SQEHQQQVAQ AVERAKQVTM 60
AELNAIIGQQ QLQAQHLSHG HGPPVPLTPH PSGLQPPGIP PLGGSAGLLA LSSALSGQSH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCCCCCCCC CCCCCCAGTT GATGTCTAGA CGGGCGGGCG GGGGCTCCCG GGGGCGCTGG 60
GGTTCTTTCC CGGAGCGATT TCTCCGTCCA CCCCACCCCC TTGCCGAGAC GGGTAGGACG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR005617--Groucho/TLE_N
IPR009146--Groucho_enhance
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF03920--TLE_N
PF00400--WD40

PRINTS

PR01850--GROUCHOFAMLY

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0001106--F:RNA polymerase II transcription corepressor activity
GO:2000811--P:negative regulation of anoikis
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0010628--P:positive regulation of gene expression

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001746	Ailuropoda melanoleuca	94.71	0.00e+00	1146.00
IUUC-Apl-003594	Anas platyrhynchos	94.97	0.00e+00	1217.00
IUUC-Aca-005053	Anolis carolinensis	93.78	0.00e+00	1174.00
IUUC-Bta-013380	Bos taurus	90.21	0.00e+00	1045.00
IUUC-Cja-019135	Callithrix jacchus	99.44	0.00e+00	1197.00
IUUC-Cpo-022495	Cavia porcellus	98.60	0.00e+00	1192.00
IUUC-Csa-024056	Chlorocebus sabaeus	99.30	0.00e+00	1214.00
IUUC-Csv-026174	Ciona savignyi	57.29	6.00e-161	561.00
IUUC-Dno-029011	Dasypus novemcinctus	98.88	0.00e+00	1192.00
IUUC-Ete-032533	Echinops telfairi	85.99	0.00e+00	1080.00
IUUC-Eca-033351	Equus caballus	99.72	0.00e+00	1200.00
IUUC-Eeu-034666	Erinaceus europaeus	99.65	0.00e+00	1080.00
IUUC-Fca-036429	Felis catus	91.67	0.00e+00	1165.00
IUUC-Fal-036696	Ficedula albicollis	97.90	0.00e+00	1258.00
IUUC-Gga-041113	Gallus gallus	98.04	0.00e+00	1243.00
IUUC-Ggo-045164	Gorilla gorilla	99.44	0.00e+00	1216.00
IUUC-Hsa-047011	Homo sapiens	99.44	0.00e+00	1216.00
IUUC-Itr-048040	Ictidomys tridecemlineatus	93.87	0.00e+00	1151.00
IUUC-Lch-050437	Latimeria chalumnae	94.81	0.00e+00	1124.00
IUUC-Loc-052819	Lepisosteus oculatus	90.90	0.00e+00	1125.00
IUUC-Laf-053862	Loxodonta africana	95.86	0.00e+00	1159.00
IUUC-Mcc-055735	Macaca mulatta	94.92	0.00e+00	1199.00
IUUC-Mmr-061207	Microcebus murinus	95.72	0.00e+00	1150.00
IUUC-Mdo-062493	Monodelphis domestica	98.74	0.00e+00	1244.00
IUUC-Mmu-063795	Mus musculus	93.53	0.00e+00	1152.00
IUUC-Mpu-065819	Mustela putorius furo	99.16	0.00e+00	1225.00
IUUC-Mlu-067047	Myotis lucifugus	99.30	0.00e+00	1182.00
IUUC-Nle-069684	Nomascus leucogenys	99.16	0.00e+00	1207.00
IUUC-Opr-071172	Ochotona princeps	99.02	0.00e+00	1196.00
IUUC-Ocu-074592	Oryctolagus cuniculus	95.66	0.00e+00	1201.00
IUUC-Oga-088629	Otolemur garnettii	96.13	0.00e+00	1155.00
IUUC-Oar-089551	Ovis aries	98.88	0.00e+00	1187.00
IUUC-Ptr-091207	Pan troglodytes	99.44	0.00e+00	1216.00
IUUC-Pan-091822	Papio anubis	94.92	0.00e+00	1199.00
IUUC-Psi-093594	Pelodiscus sinensis	94.90	0.00e+00	1180.00
IUUC-Pma-094452	Petromyzon marinus	77.58	0.00e+00	1030.00
IUUC-Pab-097687	Pongo abelii	99.44	0.00e+00	1218.00
IUUC-Pca-100675	Procavia capensis	98.95	0.00e+00	1058.00
IUUC-Pva-102355	Pteropus vampyrus	95.38	0.00e+00	1118.00
IUUC-Rno-106027	Rattus norvegicus	96.51	0.00e+00	1203.00
IUUC-Sha-107419	Sarcophilus harrisii	98.05	0.00e+00	1237.00
IUUC-Sar-113585	Sorex araneus	86.75	0.00e+00	715.00
IUUC-Ssc-116151	Sus scrofa	99.30	0.00e+00	1196.00
IUUC-Tgu-117387	Taeniopygia guttata	97.48	0.00e+00	1220.00
IUUC-Tsy-119342	Tarsius syrichta	92.20	0.00e+00	1026.00
IUUC-Tbe-127881	Tupaia belangeri	96.08	0.00e+00	1180.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence