iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oga-088629

Ensembl Protein ID

ENSOGAP00000011577.2

UniProt Accession

H0X804; H0X804_OTOGA

Genbank Protein ID

ENSOGAP00000011577

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03015177

Gene Name

TLE1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000012917.2	ENSOGAT00000012919.2	ENSOGAP00000011577.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.20e-21	75.9	624	662

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gHtd+ +c++  +d t l++G+ D+t++ WDlr+g++l+
   Q: 624  GHTDGASCIDIsNDgTKLWTGGLDNTVRSWDLREGRQLQ 662
           8***********999*********************998 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MFPQSRHPTP HQAAGQPFKF TIPESLDRIK EEFQFLQAQY HSLKLECEKL ASEKTEMQRH 60
YVMYYEMSYG LNIEMHKQTE IAKRLNTICA QVIPFLSQEH QQQVAQAVER AKQVTMAELN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAAATTGAGC GAAGAATTGA ATTGCCGGGG AGCAGAGCCG CGGCCGCCGC CAGAGCGATG 60
TTCCCGCAGA GCCGGCACCC GGTGAGGCGC GGCCCTGGGC GGGGGTGGGG TGGGGGCGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR005617--Groucho/TLE_N
IPR009146--Groucho_enhance
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF03920--TLE_N
PF00400--WD40

PRINTS

PR01850--GROUCHOFAMLY

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0001106--F:RNA polymerase II transcription corepressor activity
GO:2000811--P:negative regulation of anoikis
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0010628--P:positive regulation of gene expression

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001746	Ailuropoda melanoleuca	93.76	0.00e+00	1256.00
IUUC-Apl-003594	Anas platyrhynchos	93.66	0.00e+00	1241.00
IUUC-Aca-005053	Anolis carolinensis	97.31	0.00e+00	1297.00
IUUC-Bta-013380	Bos taurus	89.63	0.00e+00	1152.00
IUUC-Cja-019135	Callithrix jacchus	98.21	0.00e+00	1309.00
IUUC-Cfa-020611	Canis familiaris	97.93	0.00e+00	1187.00
IUUC-Cpo-022495	Cavia porcellus	97.31	0.00e+00	1300.00
IUUC-Csa-024056	Chlorocebus sabaeus	98.08	0.00e+00	1326.00
IUUC-Dno-029011	Dasypus novemcinctus	97.44	0.00e+00	1300.00
IUUC-Ete-032533	Echinops telfairi	85.64	0.00e+00	1184.00
IUUC-Eca-033351	Equus caballus	98.33	0.00e+00	1309.00
IUUC-Eeu-034666	Erinaceus europaeus	99.31	0.00e+00	1081.00
IUUC-Fca-036429	Felis catus	89.75	0.00e+00	1275.00
IUUC-Fal-036696	Ficedula albicollis	96.41	0.00e+00	1253.00
IUUC-Gmo-038805	Gadus morhua	82.40	0.00e+00	1208.00
IUUC-Gga-041113	Gallus gallus	96.79	0.00e+00	1352.00
IUUC-Gac-041999	Gasterosteus aculeatus	82.00	0.00e+00	1204.00
IUUC-Ggo-045164	Gorilla gorilla	98.21	0.00e+00	1327.00
IUUC-Hsa-047011	Homo sapiens	98.21	0.00e+00	1327.00
IUUC-Itr-048040	Ictidomys tridecemlineatus	96.96	0.00e+00	1274.00
IUUC-Lch-050437	Latimeria chalumnae	93.68	0.00e+00	1118.00
IUUC-Loc-052819	Lepisosteus oculatus	94.24	0.00e+00	1246.00
IUUC-Laf-053862	Loxodonta africana	99.23	0.00e+00	1284.00
IUUC-Mcc-055735	Macaca mulatta	94.10	0.00e+00	1309.00
IUUC-Mmr-061207	Microcebus murinus	99.23	0.00e+00	1281.00
IUUC-Mdo-062493	Monodelphis domestica	97.44	0.00e+00	1353.00
IUUC-Mmu-063795	Mus musculus	97.06	0.00e+00	1280.00
IUUC-Mpu-065819	Mustela putorius furo	97.82	0.00e+00	1333.00
IUUC-Mlu-067047	Myotis lucifugus	97.95	0.00e+00	1292.00
IUUC-Nle-069684	Nomascus leucogenys	97.95	0.00e+00	1318.00
IUUC-Opr-071172	Ochotona princeps	97.05	0.00e+00	1285.00
IUUC-Ont-072102	Oreochromis niloticus	81.15	0.00e+00	1197.00
IUUC-Ocu-074592	Oryctolagus cuniculus	94.49	0.00e+00	1309.00
IUUC-Ola-087267	Oryzias latipes	78.32	0.00e+00	1102.00
IUUC-Oar-089551	Ovis aries	96.93	0.00e+00	1284.00
IUUC-Ptr-091207	Pan troglodytes	97.82	0.00e+00	1321.00
IUUC-Pan-091822	Papio anubis	94.10	0.00e+00	1309.00
IUUC-Psi-093594	Pelodiscus sinensis	98.19	0.00e+00	1289.00
IUUC-Pfo-096239	Poecilia formosa	80.92	0.00e+00	1206.00
IUUC-Pab-097687	Pongo abelii	98.19	0.00e+00	1310.00
IUUC-Pca-100675	Procavia capensis	99.30	0.00e+00	1061.00
IUUC-Pva-102355	Pteropus vampyrus	94.00	0.00e+00	1197.00
IUUC-Rno-106027	Rattus norvegicus	95.65	0.00e+00	1315.00
IUUC-Sha-107419	Sarcophilus harrisii	92.54	0.00e+00	1273.00
IUUC-Sar-113585	Sorex araneus	86.51	0.00e+00	716.00
IUUC-Ssc-116151	Sus scrofa	97.82	0.00e+00	1302.00
IUUC-Tgu-117387	Taeniopygia guttata	96.15	0.00e+00	1329.00
IUUC-Tru-118051	Takifugu rubripes	78.62	0.00e+00	1161.00
IUUC-Tsy-119342	Tarsius syrichta	90.88	0.00e+00	1021.00
IUUC-Tbe-127881	Tupaia belangeri	95.13	0.00e+00	1290.00
IUUC-Xtr-131792	Xenopus tropicalis	89.55	0.00e+00	1237.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence