iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-005044

UUCD1 version

UUC-AnC-00911

Ensembl Protein ID

ENSACAP00000011012.3

UniProt Accession

H9GHB5; H9GHB5_ANOCA

Protein Name

Uncharacterized protein

Gene Name

UBE2E2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000011265.3	ENSACAT00000011240.3	ENSACAP00000011012.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	3.00e-50	169.6	69	204

Active Site

Position(s)	Description	Evidence
149	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkee 89
           R++kel+e++ dpp+++sa+p+ + +++ew+ +ilGp++++YeggvF l+i+f++dYPfkPPkv+f t+i+h+n++++G +Cl+ilk  
   Q: 69   RIQKELAEITLDPPPNCSAGPKGD-NIYEWRSTILGPPGSVYEGGVFFLDITFSPDYPFKPPKVTFRTRIYHCNINSQGVICLDILK-- 154
           9***********************.9************************************************************9.. PP
   S: 90   ekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvre 139
           ++Wspal++++vllsi+sll+++np++pl  ++a+++ +nr+e+++++r+
   Q: 155  DNWSPALTISKVLLSICSLLTDCNPADPLVGSIATQYMTNRAEHDRMARQ 204
           *********************************************99985 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MFVHFYLELK MSTEGQRVDD SPSTSGGSSD GDQREGVQQD QEREQVQPKK KEGKISSKTA 60
AKLSTSAKRI QKELAEITLD PPPNCSAGPK GDNIYEWRST ILGPPGSVYE GGVFFLDITF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTCGATACAA ATTTTATATT TGAAGGTATT GAAATCCAAA GAAAAGTGAC TACTAATATC 60
TGACTACTAA TATTAGTTCT GCTTCTCAAG GAATTAAGAC TGGAGACAAT GAATAACAAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005524--F:ATP binding
GO:0042296--F:ISG15 transferase activity
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0006974--P:cellular response to DNA damage stimulus
GO:0032020--P:ISG15-protein conjugation
GO:1900087--P:positive regulation of G1/S transition of mitotic cell cycle
GO:0070979--P:protein K11-linked ubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0070534--P:protein K63-linked ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Cfa-020524	Canis familiaris	94.53	5.00e-89	320.00
IUUC-Cre-022791	Chlamydomonas reinhardtii	80.13	1.00e-71	261.00
IUUC-Cho-024986	Choloepus hoffmanni	87.56	2.00e-84	304.00
IUUC-Dre-027449	Danio rerio	90.05	3.00e-89	320.00
IUUC-Dno-029130	Dasypus novemcinctus	100.00	1.00e-74	270.00
IUUC-Dme-032042	Drosophila melanogaster	87.65	2.00e-84	304.00
IUUC-Eeu-034931	Erinaceus europaeus	94.03	3.00e-91	327.00
IUUC-Fca-035425	Felis catus	97.51	1.00e-84	305.00
IUUC-Fal-037043	Ficedula albicollis	98.51	6.00e-86	309.00
IUUC-Gmo-039645	Gadus morhua	90.15	2.00e-91	328.00
IUUC-Gga-040236	Gallus gallus	98.51	2.00e-85	307.00
IUUC-Gac-041661	Gasterosteus aculeatus	90.55	1.00e-90	325.00
IUUC-Hsa-046767	Homo sapiens	98.01	2.00e-85	307.00
IUUC-Loc-052673	Lepisosteus oculatus	94.03	4.00e-94	336.00
IUUC-Mcc-055072	Macaca mulatta	98.01	2.00e-85	307.00
IUUC-Meu-056612	Macropus eugenii	94.95	7.00e-82	295.00
IUUC-Mmr-060629	Microcebus murinus	98.01	2.00e-85	307.00
IUUC-Mmu-063733	Mus musculus	97.51	3.00e-97	347.00
IUUC-Mlu-067897	Myotis lucifugus	97.51	2.00e-85	307.00
IUUC-Nle-069421	Nomascus leucogenys	98.01	2.00e-85	307.00
IUUC-Opr-071192	Ochotona princeps	82.88	1.00e-45	174.00
IUUC-Ont-071325	Oreochromis niloticus	91.54	8.00e-92	328.00
IUUC-Oan-073704	Ornithorhynchus anatinus	100.00	2.00e-74	270.00
IUUC-Pfo-097071	Poecilia formosa	86.89	3.00e-89	320.00
IUUC-Pab-098017	Pongo abelii	98.01	2.00e-85	307.00
IUUC-Pca-100367	Procavia capensis	90.55	2.00e-86	310.00
IUUC-Pva-102561	Pteropus vampyrus	98.01	2.00e-85	307.00
IUUC-Tsy-119002	Tarsius syrichta	94.17	1.00e-81	295.00
IUUC-Tni-119832	Tetraodon nigroviridis	73.11	1.00e-84	305.00
IUUC-Ttr-128358	Tursiops truncatus	98.01	2.00e-85	307.00
IUUC-Vpa-130232	Vicugna pacos	98.58	7.00e-81	292.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence